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Alba Therapeutics Announces Enrollment of Its First European Patient in Global Phase IIb Study of Larazotide Acetate for Treatment of Active Celiac Disease

- Milestone Marks the First Time a European Patient with Active Celiac Disease has Enrolled in a Clinical Trial for an Investigational Medication from Alba Therapeutics - BALTIMORE, Nov. 11 /PRNewswire/ -- Alba Therapeutics Corporation announced today that for the firs...

Results Published in the Journal 'Cancer' Demonstrate that Oral Talactoferrin Alfa is Active as Monotherapy in Previously Treated Patients with Metastatic Renal Cell Carcinoma

HOUSTON, July 1 /PRNewswire/ -- Agennix Incorporated today announced the publication of final results from a Phase 2 monotherapy trial with talactoferrin alfa in patients who had failed previous treatment for advanced or metastatic renal cell carcinoma (RCC). Results from the study, which were...

Human Genome Sciences Reports Positive Long-Term Data for LymphoStat-B in Patients With Active Systemic Lupus Erythematosus

- Phase 2 data demonstrate sustained improvement in disease activity through three years of LymphoStat-B (belimumab) therapy - - No increase in adverse events, malignancies, infections or laboratory abnormalities over time - ROCKVILLE, Md., June 12 /PRNewswire-F...

Human Genome Sciences Reports Positive Data from Long-Term Treatment with LymphoStat-B(R) in Patients with Active Systemic Lupus Erythematosus

- Sustained improvement in disease activity observed through 2.5 years of LymphoStat-B therapy in a Phase 2 continuation trial - - No observed increase in rates of adverse events, serious adverse events, malignancies and infections over 2.5 years of LymphoStat-B treatment - ROCKVILL...

Semafore's PI3 Kinase Inhibitor SF1126 is Active Against Tumor and Tumor Cells and Synergizes with Standard Chemotherapy Agents

SAN FRANCISCO, Oct. 26 /PRNewswire/ -- Semafore Pharmaceuticals Inc. announced today on the occasion of a poster presentation at the 2007 AACR-NCI- EORTC International Conference in San Francisco that its integrin-targeted PI3 kinase inhibitor, SF1126, showed synergistic effects with certain s...

Positive Clinical Data for TASQ - Active Biotech's Novel Treatment of Prostate Cancer

LUND, Sweden, March, 9, 2007-Active Biotech (ACTI.ST), today announced new positive clinical data from the Phase Ib study of TASQ, for the treatment of prostate cancer. By step-wise dose escalation, a safe dose of 1 mg/day of TASQ was achieved, which corresponds to a doubling of the previously r...

ZIOPHARM Presents Data on Orally Active ZIO-201 at AACR

LOS ANGELES--(BUSINESS WIRE)--Apr 16, 2007 - ZIOPHARM Oncology, Inc. (NASDAQ: ZIOP) announced today the presentation of preclinical data for an orally active form of ZIO-201 (isophosphoramide mustard - IPM) at the American Association of Cancer Research meeting being held in Los Angeles. Data prese...

Aranesp Phase 3 Study in Patients with Active Cancer Not Receiving Concurrent Chemotherapy or Radiotherapy Presented at AACR Annual Meeting

THOUSAND OAKS, Calif.--(BUSINESS WIRE)--Apr 16, 2007 - Amgen (Nasdaq:AMGN) today presented the results from a randomized, double-blind, placebo-controlled Phase 3 study evaluating the efficacy and safety of Aranesp(R) (darbepoetin alfa) for the treatment of anemia in patients with active cancer not...

Fractionated Radioimmunotherapy With (90)Y-epratuzumab in Non-Hodgkin's Lymphoma Appears Safe and Active in a Phase I/II Study

- Results Presented at the 12th Congress of European Hematology Association (EHA) - VIENNA, Austria, June 11, 2007 /PRNewswire-FirstCall/ -- Immunomedics, Inc. , a biopharmaceutical company focused on developing monoclonal antibodies to treat cancer and other serious diseases, today announced that...

New Positive Pre-clinical Data for Active Biotech's RA Project I-3D

LUND, June 15, 2007-Active Biotech (OMX Nordic: ACTI) presented pre-clinical results for the project I-3D at the annual EULAR (The European League Against Rheumatism, www.eular.org ) conference, June 13-16*. "The new pre-clinical data presented s...

Gentium's Defibrotide Seen as Active in Multiple Myeloma

NEW YORK--(BUSINESS WIRE)--Jun 27, 2007 - Gentium S.p.A. (Nasdaq: GENT) announced the presentation of both clinical and preclinical data that support the safety, activity, synergy and potential mechanism of action of Defibrotide in combination with anticancer therapy in multiple myeloma. Investigat...

Controlling the Spread of Healthcare Associated Methicillin Resistant Staphylococcus aureus Requires Active Surveillance

Both methicillin sensitive and methicillin resistant Staphylococcus aureus (MSSA, MRSA) can cause invasive and life-threatening infections such as osteomyelitis, septicemia, endocarditis, and pneumonia. Healthcare associated MRSA is of particular clinical importance because it is not only predict...

Regular Yoga Practice Is Associated With Mindful Eating

...he study participants was within the normal range - not surprising considering that the study sample intentionally consisted of people more physically active than the U.S. population in general. Body-mass index was lower among participants who practiced yoga as compared to those who did not (an average of 2...

Isis Reports Strong Financial Results and Highlights for Second Quarter of 2009

...to inhibit targets that could offer new avenues to treat disease, including cancer and type 2 diabetes. In addition to our clinical programs, we have active programs in many different therapeutic areas as well as established academic relationships with industry and academic leaders that expand our research...

Study Shows Brain Fitness can Save Medicare Billions

...n was based on a total of ten hours of training over one initial six-week period. Participants have been followed for more than five years. The active study team previously reported that participants who performed the computerized brain exercises had significantly improved health outcomes, as measure...

CTMM Becomes One of the World's Largest Public-Private Partnerships in Translational Medical Research

...ortality and diminished quality of life in the western world. CTMM operates by inviting, assessing and funding multidisciplinary projects that involve active participation by Netherlands-based academia and industry. All CTMM projects are judged by an independent International Scientific Advisory Committee a...

Amgen Announces Positive Top-Line Results for Denosumab in Trial for Delay of Skeletal Related Events in Bone Metastases Patients Compared to Zometa(R)

...n at an upcoming medical meeting in the second half of this year. Study Design This was an international Phase 3, randomized, doubleblind, active controlled study comparing denosumab with Zometa in the treatment of bone metastases in patients with advanced cancer (excluding breast and prostate c...

Access Pharmaceuticals Provides Update on ProLindac Clinical Development Program

... novel DACH platinum drug that has shown to be active in many solid tumors in human clinical studies. A...n cancer trial that showed that ProLindac was more active than currently available platinum drugs in that pa...is a novel DACH platinum drug that has shown to be active in many solid tumors in human clinical studies. Pl...

OPAXIO(TM) Combined with Alimta(R) Well Tolerated in Dose-Ranging Study of Patients with Advanced Non-Small Cell Lung Cancer

...ational, biologically enhanced, chemotherapeutic that links paclitaxel, the active ingredient in Taxol(R), to a biodegradable polyglutamate polymer, which res...ve, potentially sparing normal tissue's exposure to high levels of unbound, active chemotherapy and its associated toxicities. Blood vessels in tumor tissue, ...

Popular Breast Cancer Drug Used with Certain Antidepressants Puts New Jersey Women at Risk

...e among a group of antidepressant drugs known as CYP2D6 inhibitors. These drugs prevent the CYP2D6 enzyme from working properly, and cause less of the active form of tamoxifen, called endoxifen, from being produced, making the drug less effective at preventing breast cancer. Women taking tamoxifen along wit...

Economy is Driving Many Osteoporotic Women to Retire Later - But Their Ability to Work May Be Undermined by Sub-Optimal Management of Their Disease

...be passionate about their bone health given their desire and need to remain active as they age. For those with postmenopausal osteoporosis, optimally managin...ickly sought treatment from area doctor, Chad Deal, M.D. and, thanks to her active lifestyle and the benefits of medications, she is able to live a happy and ...

FDA Issues Complete Response Letter for INTUNIV(TM) (guanfacine) Extended Release for the Treatment of ADHD in Children and Adolescents

... delivery of drug throughout the day. INTUNIV is not a controlled substance and has no known potential for abuse or dependence. Guanfacine, the active ingredient in INTUNIV, is thought to work directly by binding selectively to alpha-2A adrenergic receptors located in the prefrontal cortex - an area ...

Wyeth Reports Publication of Phase 3 Data for Bazedoxifene/Conjugated Estrogens, an Investigational Compound Being Studied for the Treatment of Menopausal Symptoms

..., the incidence of treatment-emergent adverse events, breast pain, serious adverse events and withdrawals due to adverse events were similar among the active treatment groups and placebo. About SMART-1 SMART-1 was a two-year, multinational, multicenter, randomized, double-blind, placebo- and act...

R788 in TASKi3 Clinical Trial Does Not Meet Efficacy Endpoints in RA Patients Who Had Previously Failed Biologic Therapies - Results Incongruent

.... The most common adverse events in the trial overall were related to infections, though these were generally evenly distributed among the placebo and active dose group. The mean increase in blood pressure from baseline at 3 months, using a last observation carry forward methodology, was 3.2-3.6 mm...

Takeda Provides Update on the Investigational Fixed-Dose Combination of alogliptin and ACTOS(R) (pioglitazone HCl)

...experience unusually fast weight gain, fluid retention (swelling), shortness of breath, or unusual tiredness. Do not take ACTOS if you have active liver disease. Your doctor should perform a blood test to check for liver problems before you start ACTOS and periodically thereafter. Talk to your do...

Schering-Plough Announces U.S. Filing of Mometasone Furoate/Formoterol Fumarate Combination for the Maintenance Treatment of Asthma

...mbination for the maintenance treatment of asthma in patients 12 years of age and older. Mometasone furoate/formoterol fumarate combines the active ingredients of an inhaled corticosteroid, ASMANEX((R) )(mometasone furoate inhalation powder), with the long-acting beta2-agonist, FORADIL((R)) (formo...

Swissmedic Grants Debiopharm Marketing Authorisation for Moapar(R), a New Therapeutic Avenue for the Treatment of Sexual Deviations

...A), and there are fewer side effects. The approval is based on two studies showing that, combined with psychotherapy, regular injections of the active ingredient, triptorelin, over a period of eight months to seven years in male patients with sexual deviations demonstrated a good efficacy and safety ...

Swissmedic Grants Debiopharm Marketing Authorisation for Moapar(R), a New Therapeutic Avenue for the Treatment of Sexual Deviations

...A), and there are fewer side effects. The approval is based on two studies showing that, combined with psychotherapy, regular injections of the active ingredient, triptorelin, over a period of eight months to seven years in male patients with sexual deviations demonstrated a good efficacy and safety ...

National Cancer Institute Research Identifies Unique Mechanism of Brostallicin's Anti-Tumor Effectiveness

...ns can be followed by induction of a specific DNA binding protein foci that can be detected in circulating blood cells. Importantly, brostallicin was active in a trabectedin-resistant cell line. "These preclinical data provide important further insights into the specific bio-marker (tumor glutath...

Teeth and Gums Also Benefit from the Healing Power of Aloe Vera

...ility to heal burns and cuts and soothe pain has been documented as far back as the 10th century. Recently, aloe vera has gained some popularity as an active ingredient in tooth gel. Similar to its use on skin, the aloe vera in tooth gels is used to cleanse and soothe teeth and gums, and is as effective as ...

Cardax Pharmaceuticals Nominates Clinical Candidate Heptax for Liver Disease; Heptax Ameliorates Inflammation and Oxidative Stress Related to Liver Disease and Metabolic Syndrome

...as diabetes. Preclinical animal studies with the Company's compounds or its active metabolite have demonstrated reductions in blood pressure, triglycerides, c...dose control required for clinical study and it is converted to the natural active metabolite in the gastrointestinal tract. It effectively combines the prope...

Lupus Research Institute Highly Encouraged by Benlysta(TM) Trial Results

...BLISS-52, both dose levels of Benlysta(TM) plus standard of care were more effective than a placebo plus standard of care in people with serologically active systemic lupus. A total of 867 participants at 90 clinical sites in 13 countries, primarily in Asia, South America and Eastern Europe, were enrolled i...

Human Genome Sciences and GlaxoSmithKline Announce Positive Phase 3 Study Results for BENLYSTA(TM) in Systemic Lupus Erythematosus

...otal Phase 3 trials in patients with serologically active systemic lupus erythematosus (SLE). In the placeb...end the findings that emerged in the serologically active subgroup of SLE patients at Week 52 in our Phase 2...us placebo plus standard of care, in serologically active (i.e., autoantibody-positive) patients with SLE. T...

Cognition Therapeutics Closes Series A Financing to Advance Drug Candidates for Alzheimer's Disease

...expertise to the most promising early-stage technology companies in Southwestern PA to help them grow and succeed. Innovation Works is one of the most active seed-stage investors in the country, having invested in more than 120 emerging technology companies since beginning their seed fund in 1999. Those co...

PTSD Associated With Higher Alzheimer's/Dementia Risk; Moderate Alcohol Consumption May Lower it

...ble association between heart health and brain health. If people learn about and do some simple lifestyle modifications, such as being more physically active and eating a brain healthy diet, it could have an enormous impact on our nation's public health and the cost of healthcare," Carrillo added. ...

Iontophoretic Drug Delivery System (IDDS) Containing Lidocaine and Epinephrine is Effective in Reducing Pain Associated With Insertion of an Intravenous Catheter in a Phase 2 Clinical Trial

...pore Exchange Limited) announced that its improved active transdermal delivery technology, which administers...ng the venipuncture procedure were 16.4 mm for the active treatment versus 24.0 mm for the Placebo treatment...emonstrated statistically lower VAS scores for the active group as compared to the Placebo group. In additio...

Rigel's R788 Significantly Improves Rheumatoid Arthritis in Phase 2b Clinical Trial

.... The most common adverse events in the trial overall were related to infections, though these were generally evenly distributed among the placebo and active dose groups. The mean increase in blood pressure from baseline at 6 months, using a last observation carry forward methodology, was less than 0.5...

Procter & Gamble Pharmaceuticals Launches Asacol(R) HD (mesalamine) Delayed-Release Tablets

...hich are indicated for the treatment of moderately active ulcerative colitis (UC), a form of inflammatory bo...lares followed by periods of remission. Moderately active UC is characterized by tougher symptoms than mildly active UC. Asacol HD is proven to help treat these toughe...

Landmark Study for GSK's Cervical Cancer Vaccine Published in The Lancet

...tended to represent general population of sexually active young women TVC-naive included all women w...at risk of HPV infection throughout their sexually active lives. Approximately 100 types of HPV have been id...mpanies and a leader in innovation. The company is active in the fields of vaccine research, development and...

Orkin Warns of Four Pests to Avoid this Fourth of July

...ording to the Centers for Disease Control and Prevention, mosquitoes that spread WNV are most likely to bite between dusk and dawn. Ticks , most active from May through September, can transmit Lyme disease and Rocky Mountain spotted fever. To fight the bite of mosquitoes and protect family ...
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