vivo in Medical News

CRi to Distribute VisEn Medical's Portfolio of Fluorescence In Vivo Imaging Agents and Labels in North America

Distribution Partnership Expands Industry Adoption and Standardization of Leading Fluorescence Agents and Imaging Applications BEDFORD, Mass., Jan. 20 /PRNewswire/ -- Cambridge Research & Instrumentation, Inc (CRi) and VisEn Medical announced today that they have signed a non-exclusive a...

InNexus Biotechnology Completes Preclinical Study Confirming in Vivo Effectiveness and Safety of Lead Candidate DXL625, Schedules Meeting With FDA

BRITISH COLUMBIA, Canada, Jan. 13 /PRNewswire-FirstCall/ -- InNexus Biotechnology Inc., (OTC Bulletin Board: IXSBF; TSX VENTURE: IXS; http://www.ixsbio.com ), a drug development company commercializing the next generation of monoclonal antibodies based on its Dynamic Cross Linking (DXL(TM)) tec...

[video] Charles Fust, CEO of SinoFresh HealthCare, Inc. Discusses Preliminary Test Results From In Vivo Pilot Study on WallSt.net's 3-Minute Press Show

VENICE, Fla., Aug. 21 /PRNewswire-FirstCall/ -- SinoFresh HealthCare, Inc. (OTC Bulletin Board: SFSH), a developer and marketer of innovative upper respiratory system therapies, today announced that the company's CEO, Charles Fust, is featured in an exclusive interview on WallSt.net's 3-Minute...

Afid Therapeutics Inc.'s New Anticoagulant Heparin Replacement Passes in Vivo Test

LANSING, Mich., Aug. 19 /PRNewswire/ -- Afid Therapeutics, Inc. announced today that it had completed successful in vitro and in vivo (whole animal) demonstrations of the efficacy of its new "traceless" anticoagulant, which is meant to replace heparin in many applications. The in vivo and some...

DyCE(TM) (Dynamic Contrast Enhancement) Technology Now Part of CRi's Analysis Software Suite for the Popular Maestro(TM) in vivo Molecular Imaging System

WOBURN, Mass., March 20 /PRNewswire/ -- Cambridge Research & Instrumentation, Inc. (CRi) is shipping DyCE(TM) (Dynamic Contrast Enhancement), a new technology application, to users of the award-winning Maestro(TM) in vivo molecular imaging system. Customers can now generate all- optical anatom...

Sigma-Aldrich Licenses From NeuroSurvival Technologies a Leading Marker for Molecular Imaging of Apoptosis in Vivo

The marker, Apo-TRACE(TM), offers a breakthrough in advancing apoptosis-related research in a range of fields in biology and medicine ST. LOUIS, Feb. 26 /PRNewswire-FirstCall/ -- Sigma-Aldrich(TM) (Nasdaq: SIAL) and NeuroSurvival Technologies Ltd. (NST) announced today that they have si...

First Study to Show How Immune Cells 'Speak' to Each Other in Vivo

Findings confirm the existence of immunological synapses, microanatomical structures similar to those of nerve cells, in vivo.// Researchers at the Board of Governors' Gene Therapeutics Research Institute at Cedars-Sinai Medical Center have confirmed the existence of anatomical structures tha...

ConvaTec Launches Versiva(R) XC(R) Campaign and Best Practice Statement

... the launch of a new campaign and best practice statement supporting Versiva ((R)) XC ((R)) gelling foam dressing. Backed up by extensive in vivo and in vitro data, the new campaign shows how healthcare professionals can " Expect More" with Versiva ((R)) XC ((R)) dressing. The only cover dre...

Micromet, Inc. Reports Second Quarter 2009 Financial Results

...Russell 3000 index. These developments are further summarized below: On April 22, Micromet presented preclinical data showing activity in vivo and in vitro of EGFR-targeting BiTE antibodies against KRAS- and BRAF-mutated human colorectal cancer cells at the AACR meeting. The non-clinical dat...

ViroPharma Announces Support by Advisory Committee of The Office of Generic Drugs Proposed Guidelines for Developing Generic Versions of Oral Vancomycin Hydorchloride

...turers to use less rigorous standards, including in vitro rather than in vivo testing, for establishing BE rather than using comparative clinical trials...to ViroPharma, the proposed in vitro test conditions do not mimic the in vivo environment of the CDI patient and the qualitative and quantitative samene...

Growth in Personalized Medicine to Drive Alliances Between Diagnostics and Pharmaceutical Industries, According to PricewaterhouseCoopers

...erform tests outside the body, for example in a test tube. By contrast, in vivo diagnostics perform tests inside the living body, as for example in medical imaging. In vivo diagnostics industries are not reviewed in this report. ...

URI awarded $13 million grant to develop vaccines for emerging infectious diseases

...rch and Accelerated Vaccine Development (TRIAD) program will integrate vaccine design studies in silico (via computer simulation) with in vitro and in vivo research. "While the NIH grant is Professor De Groot's first award since joining the URI faculty, she has an outstanding track record of earning s...

Scientists Track Impact of DNA Damage in the Developing Brain

...y and blocked the cells from completing the cell cycle. "The cells appear to undergo permanent arrest," said McKinnon, noting it is one of the few in vivo examples of the p53 pathway leading to cell cycle arrest rather than apoptosis. In the hippocampus, which plays a role in memory and emotion, ...

Neuronal survival and axonal regrowth obtained in vitro

...latter were cultured with neurons, they promoted neuronal survival and triggered axonal growth. The promising results are now to be validated by in vivo studies. The next stage of the work, currently ongoing, applies the same method to the mouse. The approach may be used in the future in patients havin...

Is RTA a new potential option for the treatment of hydatid cysts?

... example in the symptomatic treatment of cysts in polycystic disease; cystic neoplasms; pancreatic pseudocysts, etc. This, of course, would require in vivo study, but before using a new technique on humans, preliminary experimental data are needed. ...

NeurogesX Announces Resignation of Bruce A. Peacock from Board of Directors

...includes pre-clinical compounds, which are prodrugs of acetaminophen and various opioids. The company has evaluated these compounds in vitro and in vivo and is currently seeking development partners for these programs. Safe Harbor Statement This press release contains forward-lo...

Six Scientists Receive Awards for Contributions to Alzheimer's Disease Research

...e 2009 Best Paper in Alzheimer's Disease Neuroimaging Award for his article entitled Ab Plaques Lead to Aberrant Regulation of Calcium Homeostasis In vivo Resulting in Structural and Functional Disruption of Neuronal Networks. Dr. Backsai will receive $5,000. Jennifer Whitwell, PhD, of the May...

6 scientists receive awards for contributions to Alzheimer's disease research

...he 2009 Best Paper in Alzheimer's Disease Neuroimaging Award for his article entitled Ab Plaques Lead to Aberrant Regulation of Calcium Homeostasis In vivo Resulting in Structural and Functional Disruption of Neuronal Networks. Dr. Backsai will receive $5,000. Jennifer Whitwell, PhD, of the Mayo Clini...

American Orthopaedic Society for Sports Medicine (AOSSM) Presents Prestigious Research Awards at Annual Meeting

...lowing reconstruction of an isolated posterior cruciate ligament injury: In vivo analysis during physiologic loading." The paper was voted the best overall research paper based on clinical research or human in vivo research. The authors explored how abnormal movement of the shin bone and d...

Gene's novel role may provide key to treating liver and neurodegenerative diseases

...of the human immune system responsible for fighting viruses and other pathogens that invade the body, the two scientists began developing the first in vivo knockout mouse model to closely examine FAIM's role in preventing programmed cell death. BTI Executive Director Miranda Yap, Ph.D., said, "The Immu...

Crystal Heart Award Presented to Telemundo for Coverage of Organ Donation

...tuted. Telemundo was honored for positively publicizing the message of donation throughout the Hispanic community. The segment, entitled "Al Rojo vivo con Maria Celeste" ("Live Red with Maria Celeste"), provided viewers with an honest and compassionate view of organ and tissue donation and transplant...

Fate Therapeutics Granted Exclusive License By The Regents of the University of California to Stem Cell Modulators for Osteo-Regeneration

...ng, Ph.D., professor of chemistry and biochemistry, and have been shown in vivo to exhibit osteo-regenerative activity. While many current medications ai... of these novel small molecules has been confirmed in several different in vivo proof of concept studies, and we look forward to their continued preclinic...

Scientists Gather to Discuss Novel Uses of Caliper Life Sciences' Discovery Platforms and Technology

...on to discuss the importance of Caliper's automation, microfluidics, and in vivo imaging technologies. Key themes included approaches for obtaining higher f... innovating new technology to bridge the gap between in vitro assays and in vivo results and then translating those results into cures for human disease. Ca...

AlphaRx and Gaia BioPharma Report Positive Efficacy Results in a Pre-Clinical Trial of GAI-122 Injectable Nano-emulsion for Post-operative Delirium

...ogy, providing significant neuro-protection in multiple in vitro and in vivo studies which suggest that this injectable nanoemulsion formulation has...ical results on GAI-122 injectable nanoemulsion in multiple in vitro and in vivo studies of memory impairment after prolonged anesthesia. Delirium is a co...

AUA Foundation announces 2009 Research Scholar Program award winners

...nce of Prostate-Specific Antigen and Kallikrein 2 (hK2) in Prostate Cancer Guang Jia, PhD, The Ohio State University Phase 0 MRI Study to Detect in vivo Protein Levels in Prostate Cancer HaiHong Jiang, MD, PhD, Cleveland Clinic Electrostimulation After Delivery Injury to Treat Urinary Incontinence ...

Adenoviral vector specifically targeted to EphA2 receptor in pancreatic cancer cells

...eatic cancer cell lines. Upon demonstrating specific in vitro targeting, in vivo targeting to subcutaneous growing human pancreatic cancer was tested by int...eatic cancer cells was enhanced almost 10-fold in vitro. In a subsequent in vivo study of a nude (nu/nu ) mouse model however, no increased adenoviral targe...

Frost & Sullivan Selects Bone Solutions for Technology Leadership of the Year Award

...werful binder quality that theoretically allows it to resist tensile forces at time zero, thereby potentially limiting graft-tunnel motion. Several in vivo animal and bench test studies have shown OsteoCrete(TM) to have a peak tensile load to failure that is up to three times higher that of calcium-based ...

NeurogesX and Astellas Enter Commercialization Agreement for Qutenza(TM)

...ncludes pre-clinical compounds, which are prodrugs of acetaminophen and various opioids. The company has evaluated these compounds in vitro and in vivo and is currently seeking development partners for these programs. About Astellas Pharma Europe Ltd. Astellas Pharma Europe Ltd., loca...

St. Jude Scientist Named Pew Scholar

... genome-wide approaches to identify genomic aberrations contributing to leukemogenesis and influencing leukemia outcome; the use of in vitro and in vivo experimental approaches to model genomic abnormalities in leukemogenesis; and the genetics of disease susceptibility and disease phenotype, most nota...

AlphaRx and Gaia BioPharma Provide GAI-122 Development Update

...ble therapeutics, are pleased to provide a progress report on GAI-122. GAI-122 offers significant and direct neuroprotection in both in vitro and in vivo ischemic conditions. Experimental evidence suggests that the neuroprotective action of GAI-122 is related to its' active inhibition of apoptosis or ce...

PEAK Surgical Announces First Use of PEAK PlasmaBlade(TM) in Europe

...cautery devices. In addition, preclinical results have demonstrated that the PlasmaBlade is associated with improved fascia incision healing in an in vivo model compared to the use of traditional electrosurgery. The PlasmaBlade demonstrated reductions in acute thermal injury depth, healed fascial scar wi...

Arete Therapeutics Presents Positive Clinical and Preclinical Data for AR9281

...pharmacokinetic and pharmacodynamic endpoints. In addition, AR9281 has shown favorable results in various published and proprietary in vitro and in vivo assays for potency, selectivity, efficacy, ADME, toxicity and safety. About AR9281 AR9281, an orally-administered soluble epoxide hydrola...

Canary Foundation and Stanford University Commit $20 Million for World-Class Research Center for Cancer Early Detection

...irst in the world to integrate research on both in vivo and in vitro diagnostics to deliver blood and comp...of-its-kind facility that combines in vitro and in vivo strategies to enhance future cancer detection and ...ter, and will include new faculty hires in both ex vivo and in...

Rules-Based Medicine, Inc. Names Tony Barnes to Lead Expanding Diagnostics Business

... for hundreds of proteins cost-effectively in multiple species, and from a small sample volume. The Company also offers innovative and proprietary ex vivo testing systems such as TruCulture(TM), the first fully-closed, reproducible whole blood culture system. RBM is actively developing multiplex diagnos...

A potential drug for liver carcinoma

...ty and clear anxiolytic effect. However, Chrysin is limited in its clinical application because of its modest absorption in the intestine and rapid in vivo glycosylation. To improve the biological activity of chrysin, a number of its derivatives have been prepared for biological testing. 5-allyl-7-gen-dif...

Sagent Pharmaceuticals Announces Extension of Series A Financing

...oday that it has raised $30 million in a second Series A financing extension with pre-existing and new strategic investors. The round was again led by vivo Ventures. This capital will be used to support upcoming product launches, development activities and strategic business objectives. "Sagent's bus...

Peter MacCallum Cancer Centre Expands Cancer Research Efforts with Automation Tool from Caliper Life Sciences

... and diagnostic tests more quickly and efficiently. Caliper is aggressively innovating new technology to bridge the gap between in vitro assays and in vivo results and then translating those results into cures for human disease. Caliper's portfolio of offerings includes state-of-the-art microfluidics, lab...

Light Sciences Oncology Announces Results of Study on Immunotherapeutic Mechanism of Aptocine(TM), a Novel Light-Activated Drug Therapy for Cancer

...that received immune cells from Aptocine-treated mice had significantly (p <0.0007) fewer metastases in their lungs. Aptocine acts as an in vivo vaccine--challenging a naive mouse with tumor 40 days after transferring immune cells from an Aptocine-treated animal still conferred immune protectio...

Cimzia(R) (certolizumab pegol) Now Available for Self-Administration in Adult Patients With Moderate to Severe Crohn's Disease

...rence with certain coagulation assays has been detected in patients treated with CIMZIA. There is no evidence that CIMZIA therapy has an effect on in vivo coagulation. CIMZIA may cause erroneously elevated aPTT assay results in patients without coagulation abnormalities. In controlled Crohn's clini...

Introducing COPPERTONE(R) NutraShield(R) With Dual Defense(R), New Sunscreen Line With Antioxidants To Help Promote Natural Skin Repair

...RTONE NutraShield contains specially-selected antioxidants that continue to function even in the presence of UV light. Based upon the results of an ex vivo study, the formula is proven to reduce free radical formation by 74 percent in skin exposed to UV light(1). In a clinical study conducted by an ...