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silico in Medical News

In silico modeling helps predict severity of mitochondrial disease

A team of researchers in Australia, the United Kingdom and the United States has revealed how mitochondrial diseases are passed from the mother to the next generation in a mouse model system. The study, which was published on-line in Nature Genetics*, shows for the first time how mitochondrial dis...

EPIX Pharmaceuticals, Inc. Announces August 25, 2009 for the Auction Sale of Equipment and September 30, 2009 for the Auction Sale of the Intellectual Property

... EPIX's products and services focus on the discovery and development of novel therapeutics through the use of its proprietary and highly efficient in silico drug discovery platform. The company has a pipeline of internally-discovered drug candidates currently in clinical development to treat diseases of ...

URI awarded $13 million grant to develop vaccines for emerging infectious diseases

...formatics, said the new Translational Immunology Research and Accelerated Vaccine Development (TRIAD) program will integrate vaccine design studies in silico (via computer simulation) with in vitro and in vivo research. "While the NIH grant is Professor De Groot's first award since joining the URI facul...

EPIX Pharmaceuticals, Inc. Assigns all Its Assets to Joseph F. Finn, Jr., C.P.A. for the Benefit of Its Creditors

... EPIX's products and services focus on the discovery and development of novel therapeutics through the use of its proprietary and highly efficient in silico drug discovery platform. The company has a pipeline of internally-discovered drug candidates currently in clinical development to treat diseases of ...

Cambridge Healthtech Institute's 7th Annual Bio-IT World Conference & Expo Enabling Technology - Leveraging Data - Transforming Medicine

...hnology and scientific presentations. The program features six parallel tracks in the areas of: IT Infrastructure, Genomic Medicine, Predictive and in silico Science, Computational Chemistry, Clinical and Medical Informatics, and Health IT. Keynote presentations will be featured by Chris Dagdigian, Fo...

Also in the Jan. 27 JNCI

...at is able to predict in vitro interactions between tyrosine kinases and their natural ligands and inhibitors," the authors write. "Accordingly, an in silico approach could be used to predict the biological response to new molecules conceived as small-molecule inhibitors of tyrosine kinases in the future." ...

Gene Network Sciences Announces Creation of Spin-off Entity Focused on Quantitative Finance and E-Commerce

...ual components in the system interact with one another (Reverse Engineering). These computer-assembled models are then simulated using billions of in silico queries (Forward Simulation) to discover the highest-impact components and to predict outcomes for previously unseen scenarios. About Gene Net...

Gene Network Sciences Announces Drug Development Collaboration with Biogen Idec

...nteract with one another in the complete system (Reverse Engineering). These computer-assembled models are then queried rapidly through billions of in silico experiments (Forward Simulation) to discover the highest-impact molecular targets for the disease being studied and the corresponding efficacy and tox...

Salivary diagnostics, the 'magic mirror' to your health ... at your personal computer

...onvenience, and non-invasiveness are the most critical characteristics for any diagnostic tool. A new concept, Salivaomics Knowledge Base (SKB), an in silico (i.e., performed on computer or via computer simulation) saliva diagnostic atlas, is launching today during the 37th Annual Meeting of the American As...

American Chemical Society's Weekly PressPac -- March 5, 2008

...e sorted out without losing considerably more drugs in the succeeding steps, the researchers say. MTS ARTICLE #3 FOR IMMEDIATE RELEASE Gradual in silico Filtering for Druglike Substances DOWNLOAD FULL TEXT ARTICLE http://dx.doi.org/10.1021/ci700351y CONTACT: Michael C. Hutter Saarland Unive...

Advances in drug screening: building a better haystack for the needles of tomorrow

.... The initial screen winnowed the field of potential A1 and A2 inhibitors down to two thousand candidates, enabling researchers to move from the in silico approach to the more traditional wet lab. The researchers then ran the remaining candidates through a gamut of six separate assays, each designed to f...

Grid computing offers new hope in race against bird flu

...o compute the probability that a drug-like molecule will dock with active sites on the virus and thus inhibit its action. Using the results of such in silico screening, researchers can predict which compounds are most effective at blocking the virus. This accelerates the discovery of novel potent inhibitors...

Understanding the Mechanism Underlying Embryo Development

.... This study shows that modelling is a highly useful tool for describing in silico new properties of a biological system and being able to corroborate them su...study the stability of the system they conducted around 45,000 different in silico experiments, introducing variations in twenty parameters. The results have ...

Research on Human Metabolic Disorders

...ctions in real cells." Each type of cell in the human body utilizes only a fraction of all 3,300 metabolic reactions, and scientists can create in silico any type of cell, from a heart cell to a red blood cell, with its particular complement of metabolic enzymes, and adjust their genetic or other proper...
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