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gene in Medical News

Covance to Acquire Seattle-Based Gene Expression Laboratory from Merck & Co., Inc.

PRINCETON, N.J., July 29 /PRNewswire-FirstCall/ -- Covance (NYSE: CVD ) today announced it has entered into a definitive agreement with Merck & Co., Inc. relating to the supply of genomic analysis services. Under the terms of the agreement Merck has committed to ...

Developing gene therapy to fight blindness

An international team of scientists and clinicians from the United States and Saudi Arabia are working to develop gene therapy for treating a rare, hereditary retinal disease. The therapy has been shown to restore lost vision in animal models of retinitis pigmentosa (RP). Their work is being fun...

Bcl6 gene sculpts helper T cell to boost antibody production

HOUSTON - Expression of a single gene programs an immune system helper T cell that fuels rapid growth and diversification of antibodies in a cellular structure implicated in autoimmune diseases and development of B cell lymphoma, scientists at The University of Texas M. D. Anderson Cancer Center r...

Immune System Gene Discovery Sheds Light on Staph Infections

Findings could lead to better therapies for severe forms of the disease TUESDAY, July 21 (HealthDay News) -- Researchers at the University of Texas Southwestern Medical Center have figured what genes turn on and off in a person's immune system when he or she has a severe staph infectio...

New Gene May Signal Aggressive Breast Cancer

Finding provides insight into tumor growth, metastasis, researchers say MONDAY, July 20 (HealthDay News) -- Scientists have identified a new gene that may contribute to aggressive breast cancer, new research shows. Using a new method of analyzing "microarray expression profiles" of ...

Catastrophic Epilepsy Caused by Defect in One Gene

Mouse study led to discovery of mutation and could advance treatments WEDNESDAY, July 8 (HealthDay News) -- A mutation in a single gene causes catastrophic epilepsy, U.S. scientists say. And that finding, they say, could lead to treatments or a cure for the disorder. People with cat...

Possible Gene Regions for Schizophrenia Located

Immune function genes also in the same area, researchers say WEDNESDAY, July 1 (HealthDay News) -- Immune function may play a role in schizophrenia, say scientists who found that schizophrenia patients have genetic variations on a section of chromosome 6 that contains numerous genes as...

Second gene linked to familial testicular cancer

Specific variations or mutations in a particular can gene raise a man's risk of familial, or inherited, testicular germ-cell cancer, the most common form of this disease, according to new research by scientists at the National Institutes of Health. This is only the second gene to be identified th...

Cancer Researchers Link DICER1 Gene Mutation to Rare Childhood Cancer

Finding may have implications for gene's role in other cancers Washington, DC (Vocus) June 25, 2009 -- Research published today in Science Express from the journal Science demonstrates the first definitive link between mutations in the gene DICER1and cancer. By studying...

Study pinpoints novel cancer gene and biomarker

BOSTON--Dana-Farber Cancer Institute scientists' discovery of a cancer-causing gene the first in its family to be linked to cancer demonstrates how the panoramic view of genomics and the close-up perspective of molecular biology are needed to determine which genes are involved in cancer and whic...

Clinical Studies Validate Cancer Gene Delivery Platform: Landmark Publication Confirms Rexin-G Effectively Targets Metastatic Cancers and Improves Patient Survival

SAN MARINO, Calif., June 22 /PRNewswire/ -- Epeius Biotechnologies ( www.epeiusbiotech.com ) stuns the medical and scientific communities with a dramatic demonstration of single-agent efficacy with its lead product, Rexin-G, for metastatic cancer. The landmark article (accessible online as of Ju...

Promising biomarker and candidate tumor suppressor gene identified for colorectal cancer

Researchers have identified a new candidate tumor suppressor gene in colorectal cancer and examined its use as a potential biomarker in stool samples, according to a new study published online June 17 in the Journal of the National Cancer Institute . In the study, Manon van Engeland, Ph.D., of...

Study Refutes Depression Gene Finding

But stressful life events can trigger the condition, researchers say TUESDAY, June 16 (HealthDay News) -- A new analysis upends a previous, highly acclaimed study that had concluded that a particular gene variation was associated with an increased risk of major depression. The new a...

Clarient Launches New Gene Mutation Test to Help Select Therapy for Non-Small Cell Lung Cancer

Epidermal Growth Factor Receptor Mutation Test May Be Key To Identifying Patient Response to Drug Therapies ALISO VIEJO, Calif., June 16 /PRNewswire-FirstCall/ -- Clarient, Inc. (Nasdaq: CLRT ), a premier anatomic pathology and molecular testing services resource for pathologists, oncologis...

Mapping gene expression with Gene Expression Atlas

Hinxton, 15 June 2009 Today, researchers at the European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI) launch a new database, the Gene Expression Atlas, which allows scientists to search and compare gene expression data at unprecedented detail and scope. Observing how...

LSUHSC research finds single gene controls growth of some cancers

New Orleans, LA Research led by Ashok Aiyar, PhD, Associate Professor of Microbiology at LSU Health Sciences Center New Orleans, showing that a single gene can control growth in cancers related to the Epstein-Barr virus and that existing therapeutics can inactivate it, will be published in the Ju...

Vaporized viral vector shows promise in anti-cancer gene therapy

A new lung cancer therapy employing a vaporized viral vector to deliver a cancer-inhibiting molecule directly to lung tissue shows early promise in mouse trials, according to researchers at the Ministry of Education, Science and Technology in Korea. Gene therapy is an area of great promise, bu...

Quest Diagnostics Introduces First Comprehensive Laboratory Test To Analyze KRAS, NRAS, and BRAF Gene Mutations in Reflex Testing Service

EGFR Pathway Test analyzes in sequential reflex fashion more mutations potentially inhibiting anti-EGFR therapy response in metastatic colorectal cancer patients MADISON, N.J., June 1 /PRNewswire-FirstCall/ -- Quest Diagnostics Incorporated (NYSE: DGX ), the world's leading cancer diagnost...

Findings in Epilepsy Gene in Animals May Guide Treatment Directions for Infants

PHILADELPHIA, June 1 /PRNewswire-USNewswire/ -- Researchers studying a difficult-to-treat form of childhood epilepsy called infantile spasms have developed a line of mice that experiences seizures with features closely resembling those occurring in patients with infantile seizures. These genetical...

Findings in epilepsy gene in animals may guide treatment directions for infants

Researchers studying a difficult-to-treat form of childhood epilepsy called infantile spasms have developed a line of mice that experiences seizures with features closely resembling those occurring in patients with infantile seizures. These genetically engineered mice provide a new opportunity for...

Cardium Presents Gene Activated Matrix Technology and Update on Excellarate Clinical Development Program at ASGT Annual Meeting

SAN DIEGO, May 28 /PRNewswire-FirstCall/ -- Cardium Therapeutics (NYSE Amex: CXM ) and its subsidiary Tissue Repair Company (TRC) today announced a presentation entitled "Phase 2b Study of GAM501 (Ad5PDGF-B/Collagen) in the Treatment of Diabetic Ulcers" at the Late Stage Industry Clinical Trials...

'Happy hour' gene discovery suggests cancer drugs might treat alcoholism

A class of drugs already approved as cancer treatments might also help to beat alcohol addiction. That's the conclusion of a discovery in flies of a gene, dubbed happyhour, that has an important and previously unknown role in controlling the insects' response to alcohol. Animals with a mutant v...

UCSF creates fast, affordable tool for finding gene 'on-off' switches

UCSF scientists have created a method of quickly identifying large numbers of the genetic material known as short hairpin RNA also called shRNA that turns genes on and off. The method, which the research team has used to create a library of 22,000 of these "on-off" switches for roughly 600 h...

CAP Joins Landmark Lawsuit Challenging Legality of Myriad Genetics Gene Patents

The College of American Pathologists today joined a lawsuit against the U.S. Patent and Trademark Office and Myriad Genetics, challenging the legality of Myriad's patents for the genes known as BRCA1 and BRCA2, which are indicators for hereditary predisposition to breast and ovarian cancer. ...

Breast Cancer Action Sues to End Gene Patenting

Lawsuit Seeks Increased Access to Information for Patients of Breast Cancer SAN FRANCISCO, May 12 /PRNewswire-USNewswire/ -- Breast Cancer Action (BCA) is challenging the legality of patenting human "breast cancer genes." BCA is joining the American Civil Liberties Union in suing Myriad Genetics...

Scientists identify gene in breast cancer pathway

May 12, 2009 (BRONX, NY) Scientists at Albert Einstein College of Medicine of Yeshiva University have discovered how a gene crucial in triggering the spread of breast cancer is turned on and off. The findings could help predict whether breast tumors will metastasize and also reveal potential dru...

Researchers identify the gene responsible for a rare form of congenital anemia

This press release is available in French . Montreal, May 8, 2009 The latest electronic edition of the journal Nature Genetics reports the discovery of a new gene responsible for congenital sideroblastic anemia, a rare disease, mainly characterized by the presence of ringed sideroblasts in...

Novel gene predicts local recurrence in early onset breast cancer

HOUSTON - A newly discovered gene known as DEAR1 is mutated in breast cancer and is an independent predictor of local recurrence-free survival in early-onset breast cancer, a research team headed by scientists at The University of Texas M. D. Anderson Cancer Center reports in the journal PLoS Med...

Novel gene predicts local recurrence in early-onset breast cancer

HOUSTON - A newly discovered gene known as DEAR1 is mutated in breast cancer and is an independent predictor of local recurrence-free survival in early-onset breast cancer, a research team headed by scientists at The University of Texas M. D. Anderson Cancer Center reports in the journal PLoS Med...

World's largest DNA scan for autism uncovers new gene variant for disorder

UCLA scientists, in partnership with 30 research institutions across the country, have identified a new gene variant that is highly common in autistic children. And when researchers scrutinized the activity of the gene, known as CDH10, in the fetal brain, they discovered that it is most active in ...

Mayo clinic study finds gene bringing together animal and human research in alcoholism

ROCHESTER, Minn. -- An important genetic study conducted through Mayo Clinic has identified vital new information concerning alcoholism in subjects with European ancestry, according to a recent issue of Alcohol: Clinical and Experimental Research . Research findings indicate that alcohol dep...

Mayo Clinic Study Finds Gene Bringing Together Animal and Human Research in Alcoholism

ROCHESTER, Minn., April 23 /PRNewswire-USNewswire/ -- An important genetic study conducted through Mayo Clinic has identified vital new information concerning alcoholism in subjects with European ancestry, according to a recent issue of Alcohol: Clinical and Experimental Research . ...

Throwing the micro switch: MicroRNA may link smoking risk gene to neurobiology of addiction

Philadelphia, PA, April 23, 2009 During the past several years, significant progress has been made in identifying susceptibility genes for nicotine dependence through genetic linkage and association analyses. Although a large number of genes have been associated with tobacco smoking, only a very...

Genetic source of rare childhood cancer found; gene is implicated in other cancers

St. Louis, April 20, 2009 The search for the cause of an inherited form of a rare, aggressive childhood lung cancer has uncovered important information about how the cancer develops and potentially sheds light on the development of other cancers. The finding by researchers at Washington Unive...

International team cracks mammalian gene control code

An international consortium of scientists, including researchers from The University of Queensland (UQ), have probed further into the human genome than ever before. They have discovered how genes are controlled in mammals, as well as the tiniest genetic element ever found. Their discoverie...

Mayo Clinic-led researchers confirm gene variants associated with the most common adult leukemia

DENVER - A national team of researchers led by Mayo Clinic has found that patients with chronic lymphocytic leukemia (CLL) are more likely to have similar DNA changes or variants in up to six genes, compared to people who do not have the cancer. The findings, being presented at the annual meeti...

Scientists Identify Key Gene That Protects Against Leukemia

Researchers have identified a gene that controls the rapid production and differentiation of the stem cells that produce all blood cell types -- a discovery that could eventually open the door to more streamlined treatments for leukemia and other blood cancers, in which blood cells proliferate ou...

Study IDs Gene Variants Tied to Sudden Cardiac Death

Finding could prevent fatal arrhythmias by limiting meds in those with risk factor MONDAY, March 23 (HealthDay News) -- Fourteen common genetic variants associated with a risk factor for sudden cardiac death have been identified by researchers who analyzed genetic data from more than 1...

Researchers Use Gene to End High Blood Sugar in Mice

Whether method might someday help people awaits further study WEDNESDAY, March 18 (HealthDay News) -- Delivering a gene called neurogenin3 into the livers of diabetic mice activates adult stem cells that promote steady insulin production, say researchers at the Baylor College of Medici...

Progress Reported Against Gene Involved in Hepatitis C

Finding could lead to new treatments for the disease, researchers say,,,, WEDNESDAY, March 18 (HealthDay News) -- Nearly 100 genes that support replication of the hepatitis C virus (HCV) in the human body have been identified by Massachusetts General Hospital researchers. They also...
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