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'Neglected infections of poverty' in US disable hundreds of thousands of Americans annually

An analysis published June 25th in the open-access journal PLoS Neglected Tropical Diseases highlights that diseases very similar to those plaguing Africa, Asia, and Latin America are also occurring frequently among the poorest people in the United States, especially women and children. These d...

New Cancer Drug Fights Tumors in Those With BRCA Mutations

...al and the department of cancer biology at the Dana-Farber Cancer Institute in Boston, and co-author of an accompanying journal editorial. When you disable PARP, you prevent the cell from repairing itself, he said, and cancer cells that are deficient in BRCA are much more sensitive to this effect. "When y...

SailPoint and Cyber-Ark Partner to Prevent Insider Threats

...McClain agreed, observing that, "The news is peppered with disgruntled or dishonest employees hijacking a company's network, planting malware bombs to disable the entire IT infrastructure or stealing sensitive customer data. Many of these security breaches can be pinpointed to a privileged account, but only ...

4-in-1

...ment in one go: Korean researchers led by Tae Gwan Park and Jinwoo Cheon have developed the basis for a four-in-one agent that can detect, target, and disable tumor cells while also making them macroscopically and microscopically visible. As they report in the journal Angewandte Chemie , their work involves...

Drug shows activity in men with advanced prostate cancer

...ths, and prevented the androgen receptor from activating additional genes later in the process, or "downstream." Other currently approved drugs cannot disable the receptor in such a way. The biopharmaceutical company Medivation, Inc., licensed RD162 and MDV3100 from UCLA in 2006 and has already completed ...

RF Technologies(R) to Release Help Alert(R) Wireless, Staff-Duress Call Solution at HIMSS09 Annual Conference and Exhibition

...data assistant (PDA). This PDA allows mobile access functions, including giving security personnel visual and audible notifications and the ability to disable an alarm at the point of incident. The device also provides communication with the reference tags and pendants for deployment, configuration and gener...

Neuro Kinetics to Release VEST(TM) 6.7 Software at Audiology Conference

... seen while performing more remote tests. The virtual pedals that appear on the guide are fully interactive and the user has the ability to enable or disable audio commands to help communicate pedal functionality. Users can now take advantage of the pedal controls during additional tests, including saccad...

Phyhealth Completes Funding Transaction with AccessKey IP, Inc.

...e and provides anti-theft protection for the PC, itself. With a standard USB connection, a PC user can employ the TeknoVault(TM) device to completely disable the PC preventing the disclosure of selected data on the computer. In addition, two TeknoVault(TM) users can exchange encrypted emails. Mr. Bru...

Warmer-Than-Average Temperatures Raise Migraine Risk

...." An estimated 28 million Americans suffer from migraine headaches, perhaps as many as 17 percent of women and 6 percent of men. The headaches can disable sufferers, forcing some to flee to quiet, darkened rooms for relief. Treatments include painkillers, biofeedback and newer drugs that relieve swell...

Sciton Unveils the JOULE Aesthetic Laser Platform for Physicians Battling the Economic Squeeze

...omic boost: contrary to industry trends, there are no hidden disposable costs, which can be $400 per tip, or charges for handpieces that automatically disable themselves after a limited number of pulses." Highest Value, Lowest-Per-Procedure Cost In addition to cost-optimization through more capabili...

Penn study identifies how ebola virus avoids the immune system

...l from releasing the newly made virus, thus shutting down spread to other cells. However, this study shows that the Ebola virus has developed a way to disable tetherin, thus blocking the body's response and allowing the virus to spread. "This information gives us a new way to study how tetherin works," sa...

New model system may better explain regulation of body weight

...y metabolism. Although low leptin levels are a starvation signal leading to increased food consumption and reduced energy expenditure, mutations that disable the leptin pathway are extremely rare. In fact, obese individuals usually have elevated leptin levels and show evidence of resistance to leptin's eff...

Car key jams teen drivers' cell phones

... I," Curry says. "It struck me pretty hard that something should be done." Curry's initial idea was a GPS system to detect a moving cell phone and disable it when it moved at driving speeds. Meanwhile, someone else developed a similar system based on the same idea. But it cannot distinguish if the cell p...

Gene silencer and quantum dots reduce protein production to a whisper

...ersity. Other co-authors are Maksym Yezhelyev and Ruth O'Regan at Emory and Lifeng Qi at the UW. Short pieces of RNA, the working copy of DNA, can disable production of a protein by silencing, or deactivating, a stretch of genetic code. Research laboratories regularly use the technique to figure out what...

Stanford researchers unmask proteins in telomerase, a substance that enables cancer

...e snippet to a particular gene. With the gene in hand, the researchers could find the protein made by that gene. They also used genetic trickery to disable one of the proteins, which prevented the telomerase from working. Artandi said the next step is to find small molecules that can block that newly disc...

Constant High Blood Sugar Disables Insulin 'Off' Switch

...reversing that pattern offers hope of new diabetes treatments THURSDAY, March 6 (HealthDay News) -- Chronically high blood glucose levels disable the molecular switch that normally turns off sugar production in the liver in response to increasing insulin levels, a California study finds. Thi...

Factors that enhance autonomy of cancer patients

...f not limited by the social health environment in which they live. Moreover, they reveal certain physical and mental limitations that do not generally disable them to take decisions. They are limited in the exercise of their autonomy by the scant, if nor deficient or nonexistent information that they initial...

Stroke Risk Factors Drain Memory

...I think is happening, and what a lot of other people think is happening, is that people develop small strokes that are not significantly big enough to disable you, but cumulatively knock your [mental] condition down," Howard said. Mini-strokes are not that uncommon, he said. Starting at age 55, about 10 p...

New strategies work to put cancer on the firing line

...ediatric hematologist-oncologist, showed in work published in 1998 in Science that fetuses use the enzyme IDO indoleamine 2,3-dioxygenase to locally disable a pregnant womans immune system and avoid rejection. Subsequent studies demonstrated that tumors also use IDO for protection by activating regulatory ...

McGill researchers link enzyme to breast cancer malignancy

...thor is Dr. Hicham Lahlou, a post-doctoral fellow in Dr. Muller's lab. Using transgenic mice with pre-existing cancers, the McGill team was able to disable the function of FAK in the mammary gland. "When we did that, we basically blocked tumour progression in our mouse model," said Dr. Muller, Professor o...

Cancer gene drives pivotal decision in early brain development

...stdoctoral fellow, developed a line of mice in which they could selectively disable the mouse equivalent of the human NF1 gene, Nf1, in neural stem cells. Stud...s colleagues plan to use this unique mouse model that lets them selectively disable Nf1 in brain progenitor cells to better understand the causes of neurofibro...

Northwestern exposing most deadly infectious diseases in 3-D

...view of the disease will offer scientists who design drugs a fresh opening into the bacterias vulnerabilities, and thus enable them to create drugs to disable it or vaccines to prevent it. Anthrax is just the beginning. The Feinberg School is directing an ambitious national project that will map a r...

Advances in drug screening: building a better haystack for the needles of tomorrow

...ng pathways crucial for sustaining the life of cancer cells comes the perplexing dilemma of where to find the next therapeutics that will bind to and disable those targets. While the possibilities for drug designs are near-limitless, the methods to screen drug databases and repositories are often problemati...

ReBuilder Medical Technologies, Inc. Celebrates Five Years and 50,000th Shipment

... the skin disease Molluscum Contagiosum which primarily affects children. This system uses its proprietary form of micronized amorphous silver ions to disable the molluscum pathogen without side effects. The company is currently performing research and development on a number of other products as well. ReB...

ReBuilder Medical Technologies, Inc. Hires Nurses Exclusively to Provide Customer Support

... the skin disease Molluscum Contagiosum which primarily affects children. This system uses its proprietary form of micronized amorphous silver ions to disable the molluscum pathogen without side effects. The company is currently performing research and development on a number of other products as well. ReBu...

ReBuilder Medical Technologies, Inc. Increases Manufacturing Space to Meet Demand

... the skin disease Molluscum Contagiosum which primarily affects children. This system uses its proprietary form of micronized amorphous silver ions to disable the molluscum pathogen without side effects. The company is currently performing research and development on a number of other products as well. ReB...

ReBuilder Medical Technologies, Inc. Announces UK Demand for Safe Molluscum Contagiosum Treatment Leads to Distribution Agreement with UFFE Medical, LTD. Expected 10% Sales Increase.

... the skin disease Molluscum Contagiosum which primarily affects children. This system uses its proprietary form of micronized amorphous silver ions to disable the molluscum pathogen without side effects. The company is currently performing research and development on a number of other products as well. ReBu...

ReBuilder Medical Technologies, Inc. Announces Agreement with Internet Marketer Helio Health; Anticipates 12% Additional Profit

... the skin disease Molluscum Contagiosum which primarily affects children. This system uses its proprietary form of micronized amorphous silver ions to disable the molluscum pathogen without side effects. The company is currently performing research and development on a number of other products as well. ReB...

ReBuilder Medical Technologies, Inc. Contracts with ETS to Manufacture the Newest Version of its ReBuilder Neuropathy Treatment Device; Expects Sales to Increase 30%

... the skin disease Molluscum Contagiosum which primarily affects children. This system uses its proprietary form of micronized amorphous silver ions to disable the molluscum pathogen without side effects. The company is currently performing research and development on a number of other products as well. ReB...

ReBuilder Medical Technologies, Inc. Reports Monthly Sales in 2007 Nearly Doubling Monthly Sales in 2006, Including Record Daily Sales in September 2007

... the skin disease Molluscum Contagiosum which primarily affects children. This system uses its proprietary form of micronized amorphous silver ions to disable the molluscum pathogen without side effects. The company is currently performing research and development on a number of other products as well. ReBu...

ReBuilder Medical Technologies, Inc. Increases Staffing by 30% in Three Weeks Due to Increase in Demand for All ReBuilder Medical Products

...which primarily affects children. This system uses its proprietary form of micronized amorphous silver ions in soap, toothpaste, shampoo and creams to disable the molluscum pathogen without side effects. The company is currently performing research and development on a number of other products as well. ReBu...

Older blacks and Latinos still lag whites in controlling diabetes

... decades and contribute to the much greater impact of diabetes on those two ethnic groups. The results suggest that diabetes will continue to kill and disable black and Latino adults disproportionately for decades to come. But the study delves deeper into the reasons behind this difference in blood sugar ...

ReBuilder Medical Technologies, Inc. Reports International Sales Expansion

... the skin disease Molluscum Contagiosum which primarily affects children. This system uses its proprietary form of micronized amorphous silver ions to disable the molluscum pathogen without side effects. The company is currently performing research and development on a number of other products as well. Dr. ...

Tumors use enzyme to recruit regulatory T-cells and suppress immune response

...ch Alliance Eminent Scholar in Immunogenetics. Their work published in Science in 1998 showed fetuses use IDO indoleamine 2,3-dioxygenase to locally disable a pregnant womans immune system and avoid rejection. They showed then that one way IDO suppresses the immune response is by degrading tryptophan, a na...

Protein Structure of Pathogens Associated With CF and TB Solved

...This work gives us clues to the role of this protein and we hope that future studies will identify the precise role that may provide an opportunity to disable this protein and may identify a new antibiotic that could limit the infections that can be fatal in CF patients, Gulick said. Work from other l...

Genome Annotation by Mutation

...e, then the gene will be mutated. So while the method began as a way to delete large stretches of non-gene DNA, it has the bonus of also being able to disable genes more easily and inexpensively than existing knockout techniques, Wu says. ...

Modified Drug Therapy for Alzheimers Disease

... Oklahoma Medical Research Foundation. The collaborative work of Ghosh and Tang led to the development of a treatment that could intercept and disable the disease at an early stage.In 2000, Tang identified beta-secretase, a key enzyme in the progression of Alzheimer's that triggers the formation of a...

Ex-IITian-designed Alzheimer's Drug's Human Clinical Trials Begin

...e. The drug is based on an inhibitor developed by a team of researchers at the university. The researchers say that it may help intercept and disable the disease at an early stage. "Millions of people suffer from this devastating disease and treatment options are very limited," said Professo...

Gene Thought to Help Kill Cancer Cells may Actually Help Them Thrive

...layed only a 30 percent survival rate. The findings raise the possibility of a new strategy for fighting cancer - namely, developing drugs to disable the functioning of this gene in the tumors of patients undergoing chemotherapy. P53 has long been recognized as a key player in directing chem...

Little Relief for Leprosy Patients from the Government

...hat they can to mitigate the problem. That is a very disturbing trend, say activists. Indications are that leprosy could continue to disfigure and disable Indians well into the 21st Century. GPL...
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