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Variant in Medical News

World's largest DNA scan for autism uncovers new gene variant for disorder

UCLA scientists, in partnership with 30 research institutions across the country, have identified a new gene variant that is highly common in autistic children. And when researchers scrutinized the activity of the gene, known as CDH10, in the fetal brain, they discovered that it is most active in ...

Gene Variant Tied to Schizophrenia

Discovery advances search for better treatments, experts say,,,, FRIDAY, April 10 (HealthDay News) -- U.S. researchers say they've spotted a gene variant that may raise the risk of schizophrenia in some people, a finding that may lead to new drug treatments. The study involved a gen...

New risk variant for atopic dermatitis identified

Scientists of the Max Delbrck Center for Molecular Medicine (MDC) Berlin-Buch and Charit University Medical School, Berlin, Germany, in collaboration with researchers from the Klinikum rechts der Isar of Technical University Munich and Christian Albrecht University, Kiel, have identified a gene v...

Gene Variant Tied to Cocaine-Induced Paranoia

Finding may shed light on physiology of phobias in general, study suggests WEDNESDAY, March 4 (HealthDay News) -- Genetic variants that increase cocaine addicts' risk of paranoia have been identified by U.S. researchers. In their study of almost 4,000 people of African and European ...

Gene Variant Allies Autism, Gastrointestinal Woes

It's associated with both brain development and GI system functions, study finds MONDAY, March 2 (HealthDay News) -- Researchers have identified a gene variant that is associated with both autism and gastrointestinal problems in individuals with autism. The finding may represent ear...

Gene Variant Raises Risk of Uterine Fibroids

Mutation discovered more common in white women, but different genes might raise risk in black women TUESDAY, Feb. 24 (HealthDay News) -- Researchers have found a genetic marker that may indicate if a woman has a greater chance of developing uterine fibroids, a new study says. Shorte...

Gene Variant Tied to Severity of Drinking

Marker could be used to identify those at risk and tailor treatment methods FRIDAY, Feb. 20 (HealthDay News) -- A variation in one gene may explain why some people are more heavily dependent on alcohol than are others. University of Virginia Health System researchers linked the DN...

Gene Variant Raises Risk for Brain Cancer at Young Age

But researcher stresses risk is still low MONDAY, Jan. 26 (HealthDay News) -- A gene variant that may increase the risk of developing brain cancer at a young age has been identified by French researchers. They studied 254 people with malignant brain tumors and 238 people with no can...

Gene Variant May Hike Women's Risk of Alzheimer's

Men can carry the variation as well, study finds MONDAY, Jan. 12 (HealthDay News) -- Scientists have discovered a gene variant on the X chromosome that appears to increase the risk of developing Alzheimer's disease. The risk was most pronounced in women with the variant on both X ch...

Gene Variant Tied to Smokers' Risk of Lung Cancer

2 transporters normally help protect lungs by removing inhaled toxins, study say MONDAY, Dec. 22 (HealthDay News) -- People may face an increased risk of lung cancer if they have a gene variant that metabolizes the most potent of cigarette smoke carcinogens, a new study says. The ...

NEW Line of Pushbutton Pill Cases Launched by Variant Products

ROCHESTER, N.Y., Dec. 8 /PRNewswire/ -- Variant Products, Ltd. is launching its latest new pill case designs to retailers across America and Canada. An innovative pushbutton technology was invented in-house to address ease-of-use concerns. The new look is decidedly upscale and has already been rec...

Gene Variant May Contribute to Alzheimer's Disease

The finding could open the door to improved treatments WEDNESDAY, June 25 (HealthDay News) -- Researchers say they've discovered a gene that may make it easier for people to develop Alzheimer's disease, and it could become a target for drug treatments. "This new work not only provi...

Common Genetic Variant Tied to Lung Cancer Risk

It may explain why some nonsmokers contract the disease, study says TUESDAY, May 27 (HealthDay News) -- A common genetic variant increases the risk of lung cancer, even in nonsmokers, researchers report. The findings -- that certain forms of the alpha1-antitrypsin gene double someon...

Gene Variant Boosts Risk of Severe Diabetic Eye, Kidney Diseases

Finding suggests careful use of blood-boosting drugs in anemia patients THURSDAY, May 8 (HealthDay News) -- A gene called erythropoietin (EPO) is linked to severe diabetic eye and kidney diseases, a new study finds. The study, led by a researcher at the John A. Moran Eye Center at ...

Gene Variant Boosts Risk for Stress-Related Ischemia

Patients 3 times more likely to suffer dangerous spike in blood flow to heart, study finds TUESDAY, April 22 (HealthDay News) -- Researchers have identified a gene variation in heart disease patients who are so vulnerable to the physical effects of mental stress that it causes a major ...

Gene Variant Protects Black Heart Failure Patients

Has same effect as beta blocker drugs in 40% of blacks, study finds MONDAY, April 21 (HealthDay News) -- Researchers have discovered a gene variant carried by about 40 percent of blacks that protects them after heart failure as much as widely used beta blocker drugs do. The finding ...

Gene variant predicts medication response in patients with alcohol dependence

Patients with a certain gene variant drank less and experienced better overall clinical outcomes than patients without the variant while taking the medication naltrexone, according to an analysis of participants in the National Institutes of Health's 2001-2004 COMBINE (Combined Pharmacotherapies a...

Gene variant linked to moderated symptoms of beta-thalassemia

What: Beta-thalassemia is a serious, potentially life-threatening disease that affects red blood cells, cells that carry oxygen via hemoglobin throughout the body. As part of the SardiNIA Study of Aging, supported by the National Institute on Aging (NIA), a component of the National Institutes of ...

Gene Variant Tied to More Aggressive Prostate Cancer

Men with differing version of tumor suppressor appear at increased risk, researchers say TUESDAY, Dec. 11 (HealthDay News) -- Men with a variant in the tumor suppressor gene DAB2IP may have an increased risk of aggressive prostate cancer, say researchers who examined genetic clues in Swedish and...

Gene Variant Doubles Risk of Prostate Cancer in Black Men

It may also affect other populations, researcher says FRIDAY, Nov. 2 (HealthDay News) -- A variant of a gene that doubles the risk of prostate cancer in black men has been identified, and researchers say the discovery could lead to new treatments. Almost twice as many black men dev...

Scientists discover genetic variant associated with prostate cancer in African Americans

Wednesday, October 31, 2007 Today researchers report a newly identified genetic variation that is linked to higher incidence of prostate cancer in African American men. This study, which emphasizes the importance of characterizing genetic markers associated with prostate cancer in high-risk po...

Scientists demonstate link between genetic variant and effectiveness of smoking cessation meds

A genetic variant present in nearly half of Americans of European ancestry is linked to greater effectiveness of the smoking cessation medication bupropion (Zyban), according to research by scientists supported by the National Institute on Drug Abuse (NIDA) and the National Cancer Institute (NCI),...

International Collaboration led by Dr. Pablo V. Gejman,Researcher At NorthShore University HealthSystem's Research Institute, Finds Genetic Association of Schizophrenia to Chromosome 6p Variant

The July 1, 2009 advance online edition of the journal Nature includes three companion papers describing the results of genome-wide association studies (GWAS) of schizophrenia. Schizophrenia is an elusive and severe psychiatric disorder that affects up to 70 million people worldwide. The causes o...

Gene Variant Responsible for Acquiring Intellect and Memory in Humans Identified

Chinese scientists have identified a unique gene variant linked with learning and memory, which may help understand how humans acquired intellect and language skills much faster than their closest relatives, monkeys. Researcher Bing Su and his colleagues at the Kunming Institute of Zoology...

You may Live Long and Think Clear With a Variant Gene

A variant gene has been identified by researchers that help those who have it, to live really long.// Strangely this gene seems to confer a preserving effect upon the mental faculties also. This new research work was presented by scientists from the Albert Einstein College of Medicine of Yeshiva Un...

Gene Variant associated with Schizophrenia identified

According to a team of researchers from the Edinburgh University, the risk of development of psychotic symptoms is higher in people with a variant of a gene called// neuregulin. This study was published in the journal Nature Neuroscience. 200 youths at high risk of developing schizophrenia w...

Tougher Guidelines Needed To Prevent Variant Creutzfeldt-Jakob Disease

Scientist want tougher guidelines to be imposed on re-use of surgical instruments to prevent the spread of variant Creutzfeldt-Jakob disease// (vCJD), the human form of Bovine Spongiform Encephalopathy (BSE) or mad cow disease. Even though most of the 161 cases of vCJD are linked to patients e...

Sugar variant may make a world of difference to Alzheimers disease

A novel study by Canadian researchers has revealed that variants of a sugar, is found to improve Alzheimers disease in mice//. Though these studies are still in ithe nascent stages, these findings could mean better methods of treatment to manage Alzheimers and even offset the onslaught. A typ...

Gene variant foretells diabetic neuropathy

A gene variant that is linked to an increase in the risk of Alzheimer's disease also predicts which people with diabetes are most likely to suffer neuropathy. In diabetes, impaired circulation may cause neuropathy in the lower limbs - that is, //peripheral nerve damage leading to pain and numbness....

Carnegie Mellon develops innovative method to detect genetic causes of complex diseases

...eased power in detecting gene variants associated with complex symptoms compared with other methods. In one test, GFlasso successfully detected a gene variant already implicated in severe asthma and identified two additional variants that had not previously been associated with the condition. More study of t...

Growth in Personalized Medicine to Drive Alliances Between Diagnostics and Pharmaceutical Industries, According to PricewaterhouseCoopers

...articular condition. A biomarker could be, for example, the concentration of a particular protein in someone's blood or the occurrence of a particular variant of a gene. 2. In vitro diagnostics: Diagnostic devices to perform tests outside the body, for example in a test tube. By contrast, in vivo ...

Genetic testing may be valuable in treating colorectal cancer

...of irinotecan. With genetic testing, irinotecan dosage was reduced 25 percent in individuals identified using the genetic test as having the UGT1A1*28 variant allele. The dose reduction is specified in the Food and Drug Administrationapproved drug label to minimize cases of neutropenia. Dr. Bruce Schackm...

Gene linked to increasingly common type of blood cancer

...nia and Arizona researchers have identified a gene variant that carries nearly twice the risk of developing a...ceptibility to follicular lymphoma. The SNP, a DNA variant within the more than 3-billion base pairs in the h...lymphoma. Dr. Brown said individuals who had the A variant were nearly twice as likely to develop follicular ...

Genetic Variation Associated With Survival Advantage in African Americans With HIV

...opean Americans with leukopenia. Previous studies showed that the same DARC variant conferred protection for persons of African ancestry against a particular f...ture studies will need to decipher whether the interaction between the DARC variant and low white blood cell counts results in a reduced inflammatory state," s...

Sysmex America Debuts High-end Sample Management System During AACC

...m for ESR analysis, the TS-2000 automated sample management system, Bio-Rad variant II TURBO Link "on-demand" A1c analysis instrument and kiosk-presented infor...ex HST-N hematology automation platform and the Bio-Rad Laboratories, Inc. variant II TURBO Link, enabling on-demand, automated diabetes testing in a random a...

June 2009 Mayo Clinic Health Letter Highlights Probiotics, Carotid Artery and Breast Cancer Treatments

...oesn't work well for 8 to 10 percent of women -- those who have an inactive variant of the CYP2D6 enzyme. Now, genetic markers from the blood can determine whi...moxifen. Other effective treatment options are available for women with the variant CYP2D6 enzyme. Mayo Clinic Health Letter is an eight-page monthly ne...

New Report Just Published: World Hepatitis C Virus And Therapeutics Market Report

...4 Viramidine - Next-Generation Ribavirin Drug II-4 High Mutation Rates Keep HCV Elusive II-4 Genotype I - Least Responsive and Most Common variant of HCV II-4 Table 4: Distribution of Genotypes: As a Percentage of Total Infected Population in Select Pharmaceutical Markets - USA, Franc...

Pharmasset Nominates PSI-938 as a New Nucleotide Analog Inhibitor of Hepatitis C for Preclinical Development

...ential to be combined with other direct acting antivirals targeting HCV. In addition, these purine analogs are also active against the S282T resistant variant selected in vitro by the pyrimidine analogs, and are metabolized to the active triphosphate form through a different phosphorylation pathway than th...

Living Alone Increases Odds of Developing Dementia

...variant, a known risk factor for Alzheimer's disease. The study found the highest risk of developing Alzheimer's disease among people with the gene variant who live alone after losing their partner. The findings add to a growing body of evidence that shows that social factors play an important role in ...

Study shows PET can measure effectiveness of novel breast cancer treatment

...affect the targeted tumors and how long the effects last. In the study, researchers attached the radioactive nuclide flourine-18 to an HER2-binding variant of a small protein known as an Affibody molecule. PET scans can detect the Affibody compound and allow researchers to visualize breast cancer tumors w...
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