Therapeutic

Tetanus causing toxin has therapeutic properties

Tetanus toxin, that causes the disease tetanus, have therapeutic properties that can be effective// against mental disorders like anxiety disorder, depression and anorexia. Researchers of the Universitat Autònoma de Barcelona in Spain have discovered the beneficial effects of the tetanus toxin by isolating a harmless part of the toxin called the carboxy-terminal domain. This part of th...

Understanding Chronic Infections May Help in Developing Therapeutic Vaccines

Vaccines for prophylaxis are well known. Famous vaccines include the ones against tetanus, polio, diphtheria, measles, // mumps etc.; Therapeutic vaccines to cure a condition are more recent innovation. The current vaccines tested in this area include the ones against HIV and hepatitis. The therapeutic vaccines aim to enhance the immune system's ability to combat an infectious agent, such as a vi...

Therapeutic cloning by regenerating stem cells from heart muscles

Professor Hiroaki Matsubara and colleagues from Kyoto University Hospital has regenerated stem cells from cardiac muscle cells. The cardiac muscle cells were obtained from the heart tissue// of human volunteers. The researchers injected the regenerated stem cells from humans into the heart of the mouse, which had a damaged heart muscle and blood vessels, the scientists found that the therapy heal...

Therapeutic Genes Transferred By Viral Vector Through T Cell Masking

Dr. Richard Vile, Mayo Clinic Molecular Immunologist and his team has found a new virus based gene therapy delivery system for the treatment of cancer, inflammation and autoimmune diseases. The new delivery system acts as a “T // cell Therapeutic hitchhiker”, by which the Therapeutic virus containing the required genes are transferred into the T cells in the immune system, as the T cells are the...

Therapeutic Monoclonal Antibody Production Is More Profitable Than Small Molecule Drugs

New study has suggested that therapeutics based on monoclonal antibodies (mAbs) are fare more likely to be commercially successful than their small molecule predecessors. According to a study completed by // consultancy Propagate Pharma, about half the mAbs launched so fare appear to be profitable. That means mAbs are recouping more in revenues than their estimated $1 billion to $1.8 billion cost...

Simplest therapeutic regimen found less effective against HIV

Antiretroviral therapy for treatment of Human Immunodeficiency Virus type 1 (HIV-1) infection has improved steadily since the advent of combination therapy in 1996//. More recently, new drugs have been approved, offering added dosing convenience and improved safety profiles, while some previously popular drugs are being used less often as their drawbacks become better defined. Resistance testing...

Mice model to study bacterial therapeutic pathway

Researchers from Flanders Interuniversity Institute for Biotechnology are finding out the mechanism behind bacterial resistance from studying certain mice which had the capacity to resist bacterial infection. // The researchers are using this mice model to find out new therapeutic pathways which could help in treating bacterial infections. Bacterial infections are the most common infe...

Functional Differences In Estrogen Receptor Could Be A Therapeutic Target

Differences in a newly uncovered estrogen receptor could turn out to be an important therapeutic target besides playing a vital role in signaling //other target tissues like uterus and prostate tissues. These new findings could significantly advance the understanding of the effects of estrogen in breast cancer and point the way towards new and potentially more effective treatments of...

Clinical-trials Show Increased Therapeutic Activity of Pycnogenol than Daflon

A new research has found that Pycnogenol? is more effective than Daflon?, a combined form of diosmin and hesperidin commonly used to treat chronic venous insufficiency// (CVI). According to the journal of Clinical and Applied Thrombosis/Hematosis, the supplementation of Pycnogenol? shows increased symptom reduction in the patients suffering from Chronic venous insufficiency. It is an...

Safety of Cancer Therapeutic Viruses Enhanced

Cancer killing viruses have been made more specific to cancer tumor cells in addition to enhancing its therapeutic effectiveness by Mayo Clinic researchers working with colleagues in Germany.// This was a much-needed multilevel safety feature for viruses used to treat cancer. They did this by engineering a modified measles virus that turns on only in the presence of secretions specific...

Researchers Enhance Safety and Effectiveness of Therapeutic Virus that Fights Cancer

Mayo Clinic researchers working with colleagues in Germany have devised a much-needed multilevel safety feature for viruses used to treat cancer. In the process of making// cancer-killing viruses more specific to cancer tumor cells, they report having improved the therapeutic effectiveness of viruses. They did this by engineering a modified measles virus that turns on only in the presence of secr...

Human Embryonic Stem Cells Could Be Later Used In Therapeutic Cloning

according to the research conducted by the stem cells researchers across the world and researchers from the Burnham Institute //for Medical Research (BIMR)and Illumina Inc., it was found that embryonic stem cell research has inherent characteristics which make it pluripotent and totipotent. This sets aside the embryonic stem cell from that of the other normal adult cells. These characte...

Contemporary Therapeutic Guidelines For HIV Patients

In its quest to vanquish the big time killer AIDS/ HIV infection worldwide Center for AIDS Research at Case Medical Center spearheaded// by Dr Benigno Rodriguez M.D and his extensive team of experts on AIDS/HIV in the U. S. have presented their latest findings in the current issue of Journal Of American Medical Association. Current therapeutic guidelines have been questioned by the latest finding...

Potential New Therapeutic Target for Asthma, Allergies and Cancer

Virginia Commonwealth University researchers have identified how a bioactive molecule involved with allergy, inflammation and cancer is transported out of mast cells, according to findings //published online this week in the Proceedings of the National Academy of Sciences. Mast cells are specialized cells that react to allergy-causing agents by releasing substances that trigger the bod...

VBI Provides Potential Targets to Diabetes Therapeutics

Virginia Bioinformatics Institute (VBI) Assistant Professor Biswarup Mukhopadhyay has provided important information for researchers designing drugs for type 2 diabetics in the// December 22, 2006, Journal of Biological Chemistry. The information should in time help researchers to identify potential targets for docking inhibitors that will slow down, but not fully eliminate, the body'...

Germany's Therapeutic Mud Baths Have Healing Qualities

At first glance, it is difficult to believe anyone would willingly get into a mud bath. But thousands of Germans bathe in them every year to benefit their health//, and these warm baths have a long history as a natural cure. Patients have sought out the brownish-black mud in Bad Wilsnack in Brandenburg for more than a century, originally to ease back pain or arthritis. Today, it is al...

Macca Finds Making Music Therapeutic

For Beatles singer Sir Paul McCartney, making music is what helps relieves his tensions. The 64-year-old who is in between a nasty divorce battle with estranged wife Heather Mills insisted that his music is not affected by his personal life. "I don't see it as anything to do with my personal circumstances," Contactmusic quoted McCartney, as saying. The singer, songwriter and multi-...

CELL THERAPEUTICS PAYS Heavily to Resolve Dispute FOR ALLEGED ILLEGAL MARKETING OF CANCER DRUG

Cell Therapeutics Inc (Seattle WA) has agreed to pay the US $10.5 millon to resolve allegations of the company's alleged illegal marketing// of the anti-cancer prescription drug Trisenox, the US Justice Department announced earlier this month. According to the government's complaint, CTI promoted the drug for various uses that were unapproved by the US Food & Drug Administration (FDA)...

Legalization of Therapeutic Abortion in UAE on the Cards

A senior official of the United Arab Emirates (UAE) said the government is working to draft a law allowing therapeutic abortions, as part of the country's prevention// programme of genetic disorders. "We are studying it from two ways: on the mother or child's health. But the choice to have the abortion will be under the umbrella of religion. Whatever we decide has to be within the rel...

New Therapeutic Approach for Autoimmune and Inflammatory Diseases

Researchers at the La Jolla Institute for Allergy & Immunology (LIAI) made an important finding, which could eventually lead to a new therapeutic approach for treating autoimmune and inflammatory diseases such as rheumatoid arthritis, colitis, psoriasis and others. .The studies, conducted in laboratory mice, demonstrated the role of retinoic acid, a substance derived when Vitamin A is...

Australian State Approves Therapeutic Cloning

Lawmakers in Australia's most populous state voted Thursday to overturn a ban on the use of cloned human embryos for stem cell research despite strong opposition from the Catholic church. Controversial new legislation allowing therapeutic cloning was passed in New South Wales by 65 votes to 26. The legislation needs to be approved by the upper house of the state parliament before b...

New Platform for Regulating Expression of Therapeutic Genes Unveiled

A new platform for regulating the expression of therapeutic genes, which will have major implications for gene and cell therapy, was presented today at the 10th Annual Meeting of the American Society of Gene Therapy (ASGT) in Seattle. Carefully regulating gene expression is crucial to the success of gene and cell therapy. For many applications, gene transfer is being employed to en...

Legalization of Therapeutic Abortion in UAE on the Cards

A senior official of the United Arab Emirates (UAE) said the government is working to draft a law allowing therapeutic abortions, as part of the country's prevention programme of genetic disorders. "We are studying it from two ways: on the mother or child's health. But the choice to have the abortion will be under the umbrella of religion. Whatever we decide has to be within the re...

Genopole(R) is Organizing an Advanced Course on Stem Cells and Their Therapeutic Applications

From November 18th to 22nd, 2007, under the responsibility of Marc Peschanski, director of I-Stem(1), Genopole(R) is organizing an advanced course on stem cells and their therapeutic applications, aimed at exploring the latest advancements of research in this field, with input from 17 renowned specialists worldwide. Major topics to be covered include embryonic stem cells, mesenchymatic, hematopo...

China Biopharma to Introduce an Immunotherapeutic Vaccine into China

China Biopharma, Inc., has reached a tentative agreement with Delmont Laboratory to introduce its immunotherapeutic vaccine Staphage Lysate that treats diseases of staphylococcal infection . According to this initial agreement, Delmont Laboratory will supply bulk materials and China Biopharma will contract local manufactures for the final packaging in China. CBPC will also conduct a...

Cytokine IL6 as a New Chemotherapeutic Target for Ras-driven Cancers

Dr. Christopher Counter and colleagues at the Duke University Medical Center have identified IL6 as a new target in the battle against Ras-induced cancers . Ras is a key intracellular messenger protein that directs, among other things, cell growth and proliferation. Over-expression of the Ras oncogene, or of its growth-promoting pathway, is an integral step in the development of a numb...

Therapeutic Cancer Vaccine Trials

Ongoing therapeutic cancer vaccine trials have yet to show evidence of vaccines spurring a patients immune system to shrink tumors -- yet patients who receive these vaccines in trials tend to live longer and respond better to subsequent treatment. In the July 1 issue of Clinical Cancer Research, a journal of the American Association for Cancer Research, a team of National Cancer I...