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Suppression in Medical News

Herpes Suppression May Not Prevent HIV Infection

Study with antiviral aciclovir shows no added benefit THURSDAY, June 19 (HealthDay News) -- The herpes drug aciclovir (Zovirax) doesn't reduce the risk of HIV-1 infection in people who have sex with men infected with genital herpes, a U.S. study finds. Previous research has shown th...

Vicriviroc Demonstrates Potent and Sustained Viral Suppression Through 48 Weeks of Therapy in Treatment-Experienced HIV-Infected Patients

Results of VICTOR-E1 Phase II Study Presented at 15th Conference on Retroviruses and Opportunistic Infections (CROI) BOSTON, Feb. 6 /PRNewswire-FirstCall/ -- Schering-Plough Corporation (NYSE: SGP ) today reported that final results of a Phase II clinical study showed vicriviroc,...

Ninety-one Percent of BARACLUDE(R) (entecavir) Treated Patients in a Four-Year Cohort Demonstrated Virologic Suppression to Undetectable Levels

- In this Cohort of Nucleoside-Naive Chronic Hepatitis B e-Antigen (HBeAg) Positive Patients, Resistance Monitoring Identified One Patient with Genotypic Resistance to BARACLUDE - BOSTON, Nov. 2 /PRNewswire-FirstCall/ -- Bristol-Myers Squibb Company (NYSE: BMY ) today announc...

MicroRNA undermines tumor suppression

FINDINGS: Scientists at the Whitehead Institute for Biomedical Research and the National University of Singapore have discovered the first microRNA (miRNA) capable of directly tamping down the activity of the well known tumor-suppressor gene, p53, While p53 functions to prevent tumor formation, th...

Safe to Stop the Flow?: Differing Attitudes Found Between Women and Doctors Concerning Menstrual Suppression

Two Thirds of Women Interested in Stopping their Periods, But Unsure About Medical Implications PHILADELPHIA, Oct. 3 /PRNewswire-USNewswire/ -- More than two thirds of women in a national survey say that they are interested in suppressing their menstrual periods but many of them aren't sure ...

Differing attitudes found between women and doctors concerning menstrual suppression

PHILADELPHIA More than the two thirds of the women in a national survey say that they are interested in suppressing their menstrual periods but many of them arent sure if its safe. Yet when physicians are polled, 97 percent say that continuous oral contraceptive therapy to suppress menstruation i...

Pill box organizers increase HIV patients' adherence and improve viral suppression

Inexpensive pill box organizers are an easy, successful, and cost-effective tool to help patients take their medications as prescribed, according to a new study of low-income urban residents living with HIV infection by authors from the Berkeley School of Public Health and the University of Califo...

Role of MicroRNA in Cancer Suppression Identified

Rosetta Genomics Ltd, a leading microRNA company, announced today research published in the journal Molecular Cell by scientists from the Weizmann Institute of Science and Rosetta Genomics . The findings suggest the potential for a specific, single microRNA (miR-34a) to be used as a drug candidate ...

Should Menstrual Suppression Be a Lifestyle Choice?

Menstrual suppression has been recommended for medical conditions such as endometriosis, but it is also being proposed as a lifestyle choice for women who dislike menstruation or find it inconvenient. But is menstrual suppression safe and is it a reasonable lifestyle choice, asks Paula De...

Should Menstrual Suppression Be a Lifestyle Choice?

Menstrual suppression has been recommended for medical conditions such as endometriosis, but it is also being proposed as// a lifestyle choice for women who dislike menstruation or find it inconvenient. But is menstrual suppression safe and is it a reasonable lifestyle choice, asks Paula Der...

Long-time Gastric Acid Suppression Does Not Increase The Risk Of Cancer

The use of H2 blocker drugs such as ranitidine (Zantac) and cimetidine (Tagamet)and proton pump inhibitors like omeprazole //(Prilosec) reduce stomach acid. This was believed to increase the risk of cancer of the esophagus or stomach. However, a new finding says that H2 blockers and proto...

Transplant Cures Rats’ Type 2 Diabetes without Need for Immune Suppression Drug

An approach proven to cure a rat model of type 1 or juvenile-onset diabetes also works in a rat model of type 2 or adult-onset diabetes//, according to a new report from researchers at Washington University School of Medicine in St. Louis. "Finding that we can cure type 2 diabetes in the same ...

Adrenal Suppression not predicted by inhaled corticosteroids

It is proved beyond doubt that asthma is affected beneficially by long-term treatment with inhaled corticosteroids (ICS) in childhood//. Although there is a lot of side affects that are associated with it. Which include adrenal suppression and growth deceleration; continue to be of concern to...

Orexigen(R) Therapeutics Announces Second Quarter 2009 Financial Results

...f of 2009. Each product candidate is designed to act on a specific group of neurons in the central nervous system with the goal of achieving appetite suppression and sustained weight loss, through combination therapeutic approaches. Further information about the Company can be found at http://www.Orexigen.com....

Ferring Pharmaceuticals Announces Trade Name FIRMAGON(R) (degarelix for injection) for Advanced Prostate Cancer Treatment

...treatment advances in the future." FIRMAGON provides fast, long-term suppression of testosterone, a hormone that stimulates prostate cancer growth.(1-3) Ph...epot(R))* in reducing and sustaining castrate levels of testosterone.(1,2) suppression of testosterone to castrate levels occurred significantly faster in patient...

Five Questions About Eczema

...own to be effective on sensitive areas. (21) TCIs have not been associated with certain side effects such as skin thinning, stretch marks, and growth suppression in children. (22) The most common application side effects of TCIs include the sensation of burning or itching. (23) These occur at the beginn...

Millennium Pharmaceuticals Inc./Lymphoma Research Foundation funds lymphoma research

...f a pathway in tumor cells that leads to increased resistance to standard chemotherapy. Dr. Fu will conduct a pre-clinical study to determine whether suppression of miR-17~92 will improve the effect of chemotherapy. His study will thus provide a novel approach to treating MCL patients. "Dr. Fu's elegant pr...

New Anesthesia May Be Safer for Critically Ill

...ically ill patients. "We have shown that making a version of etomidate that is broken down very quickly in the body reduces the duration of adrenal suppression while retaining etomidates benefit of keeping blood pressure much more stable than other anesthetics do," study leader Dr. Douglas Raines, of Massachu...

Orexigen(R) Therapeutics Prices Public Offering of Common Stock

...f of 2009. Each product candidate is designed to act on a specific group of neurons in the central nervous system with the goal of achieving appetite suppression and sustained weight loss, through combination therapeutic approaches. Further information about the Company can be found at http://www.orexigen.com....

Mass. General team develops potentially safer general anesthetic

...d pressure seen with most anesthetics or prolonged suppression of adrenal gland activity, a problem with the orig...uickly in the body reduces the duration of adrenal suppression while retaining etomidate's benefit of keeping blo...often used to induce anesthesia, but since adrenal suppression sets in quickly and can last for several hours to ...

Orexigen(R) Therapeutics Announces Proposed Public Offering of Common Stock

...f of 2009. Each product candidate is designed to act on a specific group of neurons in the central nervous system with the goal of achieving appetite suppression and sustained weight loss, through combination therapeutic approaches. Further information about the Company can be found at http://www.orexigen.c...

Mass. General-based research center will investigate why immune system fails to control hepatitis C

...GH) has been awarded $15 million from the National Institute of Allergy and Infectious Diseases to investigate how the hepatitis C virus (HCV) resists suppression and clearance by the immune system. The five-year grant will support a Cooperative Center for Translational Research in Human Immunology, which also ...

Avidas(TM) Pharmaceuticals and LaRon(TM) Pharma Inc. Announce Co-Promotion Agreement

...e of a potent topical steroid applied to a large surface area or under an occlusive dressing should be evaluated periodically for evidence of HPA axis suppression by using the urinary free cortisol and ACTH stimulation tests. For full Prescribing Information, please visit http://www.scalacortdk.com ...

96-Week Safety and Efficacy Findings Presented for INTELENCE(TM) (etravirine) As Part of HIV Combination Therapy

.... Ninety-one percent of patients in the INTELENCE arm who achieved an undetectable viral load (<50 copies/mL) at week 48 maintained virologic suppression through week 96 vs. 88 percent of patients in the placebo arm. DUET-1 and -2: 96-Week Safety Data In the DUET studies, the ...

-Contrave(R) Obesity Research Phase 3 Program Meets Co-Primary and Key Secondary Endpoints; Exceeds FDA Efficacy Benchmark for Obesity Treatments-

...f of 2009. Each product candidate is designed to act on a specific group of neurons in the central nervous system with the goal of achieving appetite suppression and sustained weight loss, through combination therapeutic approaches. Further information about the Company can be found at http://www.Orexigen.com....

Max Muscle Sports Nutrition Answers Call For Safe Science-Based Weight Loss

...ate fat loss, increase energy and elevate the body's metabolism." Max De-Lite Activated Weight Loss Formula promotes weight loss and appetite suppression by containing three Proprietary Patented ingredients for safe and effective weight loss including, Slimaluma®, Advantra Z®, and Clarinol&trad...

State privacy rules reduce electronic medical sharing by 24 percent, warns Management Insights

...thors find that such statutes reduce EMR adoption by 11% per three-year period or 24% overall. The paper presents evidence that this is because of the suppression of the interactive benefit of this technology by privacy laws. ...

Study finds citrus-derived flavonoid prevents obesity

...as that the effects were independent of caloric intake, meaning the mice ate exactly the same amount of food and the same amount of fat. There was no suppression of appetite or decreased food intake, which are often the basis of strategies to reduce weight gain and its metabolic consequences." While grapefru...

U.S. Women's Chamber of Commerce Advocates Strong Healthcare Reforms in Support of American Values

... other spurious financial manipulation that has nearly ground America's economy to a halt." The report details troubling statistics regarding the suppression of business growth, lack of access to affordable healthcare for women, crippling economic damage caused by America's healthcare crisis and details spe...

Atrial fibrillation in endurance athletes still poses problems for sports cardiologists

...heart fibrosis induced by endurance exercise. The anti-fibrotic effect of losartan, an angiotensin type-II receptor antagonist, appears to be mediated suppression of angiotensin II-induced proliferation of fibroblasts. Again, markers of fibrosis were reduced by administration of losartan. ...

Fears About Pregnancy and cats Should not stop Those who want to Adopt a cat

... In cats, trimethoprim-sulfonamide drugs may be prescribed, but they must be used carefully and for a limited time because they can cause bone marrow suppression resulting in a compromised immune system, she said. Clindamycin and Pyrimethamine are other effective and commonly used drugs, but the later should b...

Inoperable Colon Cancer Responds to New Treatment

...cancer treatment . Most patients never experience effects commonly affiliated with chemotherapy or radiation (nausea, vomiting, hair loss, bone marrow suppression or immune system suppression). An experienced physician prescribes and monitors the outpatient treatment. NeoPlas Innovation's web site, www.neop...

Orexigen(R) Therapeutics Announces In-Licensing of Key Patents to Further Strengthen its Intellectual Property Estate for Contrave(R)

...evelopment. Each product candidate is designed to act on a specific group of neurons in the central nervous system with the goal of achieving appetite suppression and sustained weight loss. Further information about the Company can be found at http://www.orexigen.com . Forward-Looking Statements ...

Immune cells ameliorate hypertension-induced cardiac damage in mice

...nsion II-induced target organ damage. The researchers wanted to know if the suppression of activated immune cells by Treg cells could reduce cardiac damage. An..., it is not known what side effects would occur in human patients following suppression of the immune system with Treg cells . Nevertheless, Dr. Kvakan and Dr. ...

Breast-feeding OK for Most Moms with MS

...during breast-feeding would suggest that pregnancy hormones, which decrease dramatically once the baby is delivered, cannot be the only reason for the suppression of MS. "Previous research has ignored the postpartum factor, and what our study suggests -- if these findings can be repeated -- is that it's proba...

Researchers develop light-treatment device to improve sleep quality in the elderly

... when a person is in a dark environment and low levels during the day. After only one hour of light exposure, the light-induced nocturnal melatonin suppression level was about 35 percent for the low light level and about 60 percent for the high light level. In addition, the higher level of blue light suppres...

Why do people with Down syndrome have less cancer?

...e was right: blood vessels budded in the Down teratomas, but never fully formed. "The studies in the iPS cells helped validate and confirm that the suppression of angiogenesis that we saw in mouse models also holds true in humans," says Ryeom. "It suggests that these two genes might point to a viable cancer t...

Research Reveals How Down Syndrome Shields Against Cancer

...on was blocked," Ryeom said. "This told us that Dscr1 played a critical role in suppressing tumor angiogenesis." Dscr1 alone resulted in some tumor suppression but there may be as many as five genes involved in the action. "Dscr1 is necessary but not sufficient," Ryeom explained. In fact, Ryeom and her c...

Neurocrine Announces Full Year Results from 603 Study (Petal Study) of Elagolix for Treatment of Endometriosis Pain

...of subjects had evidence of ovulation within 4 weeks of stopping. Prolonged suppression of ovulation was documented, even out to Week 48 in the DMPA subjects who a...post-treatment period (mean 0.4 per day). No pattern of excessive estradiol suppression was detected. The twelve-month data from the Petal Study will be prese...

Turmeric extract suppresses fat tissue growth in rodent models

...supplementation," said Meydani, who is also a professor at the Friedman School of Nutrition Science and Policy at Tufts. "In those mice, we observed a suppression of microvessel density in fat tissue, a sign of less blood vessel growth and thus less expansion of fat. We also found lower blood cholesterol levels ...
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