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Smallpox in Medical News

Scientists discover how smallpox may derail human immune system

GAINESVILLE, Fla. University of Florida researchers have learned more about how smallpox conducts its deadly business discoveries that may reveal as much about the human immune system as they do about one of the world's most feared pathogens. In findings to be published this week in the onlin...

Japanese Researchers Develop New Smallpox Vaccine

No serious side effects are found in latest test, study reports,, TUESDAY, March 10 (HealthDay News) -- A third-generation tissue-cultured smallpox vaccine shows promise, Japanese researchers report. "The threat of smallpox bioterrorism has prompted reconsideration of the need for s...

NIH awards LIAI major grant to test safety of new smallpox treatment

SAN DIEGO (May 8, 2008) The La Jolla Institute for Allergy & Immunology (LIAI) has received a $7.1 million grant from the National Institutes of Health (NIH) to fund safety and effectiveness testing of an antibody treatment that quickly fights the smallpox virus. The treatment could be the natio...

Bavarian Nordic Reports Positive Data from First EUA Enabling Study with IMVAMUNE(R) Smallpox Vaccine Candidate

WASHINGTON, DC, November 29 /PRNewswire-FirstCall/ -- Bavarian Nordic reports the successful completion of a large, placebo-controlled Phase II trial in 745 healthy subjects who received either one or two doses of IMVAMUNE(R) next-generation smallpox vaccine candidate. The results of this stud...

Genetic Variations Leads to Fever After Smallpox Vaccination

St. Louis researchers have identified common DNA variations that underlie susceptibility to fever after smallpox vaccination. Most of the eight genetic alterations the scientists identified increased the likelihood of fever after smallpox vaccination. A few, however, reduced fever risk. The s...

Study Finds That Lincoln Suffered from Smallpox During Gettysburg Speech

US President Abraham Lincoln delivered his famous Gettysburg Address, he was in the early stages of a deadly form of smallpox, a new study by two University of Texas researchers, has revealed. Some historians, who recognized that Lincoln was ill, following his Gettysburg speech, asserted t...

Toddler Infected With Rare Side Effect Of Smallpox Vaccination Recovering

The quote there is nothing as lovely as the feet of those who bring good tidings, could not be more apt . There is finally, good news from the University of Chicago Comer Childrens Hospital, which was witness to one of the most horrific side effects of the smallpox vaccine, and unfortunately, on...

HHS Buys Next Generation Smallpox Vaccine

WASHINGTON, HHS Secretary Mike Leavitt announced today that HHS has awarded a contract for $500 million to Bavarian Nordic A/S of Copenhagen, Denmark to manufacture and deliver 20 million doses of a next generation modified vaccinia Ankara (MVA) smallpox vaccine. The vaccine would be recom...

New Smallpox Vaccine Contract: Five Years in the Making

On December 13, 2002, fifteen months after the 9/11 terrorist attacks, President George W. Bush went to Room 450 of the Dwight D. Eisenhower Executive Office Building next door to the White House and said: "We know that smallpox still exists in laboratories, and we believe that regimes host...

New Evidence Links Smallpox Vaccination Side Effects to Genetic Factors

Boffins have found new evidence that supports the link between genetic factors and certain adverse reactions related to smallpox vaccination . Immunization with live virus particles, as in the smallpox vaccine, is sometimes found to cause reactions that range from fatigue to serious illness...

Toddler Infected With Rare Side Effect of Smallpox Vaccine

In a gut wrenching tragedy a U.S soldier father passed on a rare side effect of the smallpox vaccination he had taken, eczema vaccinatum, to his 2-year-old son.// The boy who is currently being treated at University of Chicago's Comer Children's Hospital has developed a virulent rash over 80 ...

Penn Researchers Throw Light on the Structure Of Smallpox Virus Protein

Researchers at the University of Pennsylvania School of Medicine have shown the form of a crucial smallpox virus and the manner with which it attaches// itself to the DNA .The enzyme, which is named, as a topoisomerase has become a very important drug target for devising novel methods to combat sma...

Drug Firm Offers to Donate Smallpox Vaccine

There is no treatment for smallpox, which kills about 30% of its victims and leaves others covered in sores. But giving a vaccine within days of exposure can protect against illness. A French drug company offered to donate up to 90 million doses of decades-old smallpox vaccine and the United States...

Problematic Use of smallpox vaccine

The USA is accumulating an abundant supply of smallpox vaccine, but health officials say they are not recommending that it be widely used- yet. The vaccine currently on hand, 16.8 million doses in a government stockpile// and more than 80 million doses that drug maker Aventis Pasteur says it will a...

Is Smallpox Threat Real ?

Smallpox, a highly contagious virus that kills at least 30 percent of its victims and disfigures many who survive, was eradicated from the globe more than two decades ago. Scientists retained stocks of the variola virus, which causes the disease, and stored them in secure laboratories in Atlanta, G...

National Foundation for Infectious Diseases honors VCU physician with Maxwell Finland Award for 2010

...gland Journal of Medicine and was among the leading commentators on swine flu and the SARS outbreak. He was at the forefront of the national debate on smallpox vaccination. His research focuses on the epidemiology of hospital-acquired infections and clinical trials of antisepsis scrub agents to treat or p...

Smallpox -- the death of a disease

...ield staff. On October 26, 1976, the last case of smallpox occurred. The disease that annually had killed two...nd in just over ten years. "The eradication of smallpox was the greatest public health accomplishment of t...Elizabeth Fenn, author of Pox Americana: The Great smallpox Epidemic of 1775-82, and Associate Professor of Hi...

Aethlon Medical Discloses New HIV/AIDS Treatment Data

...rd Flu), the reconstructed 1918 influenza virus (r1918), West Nile virus (WNV), and Vaccinia and Monkeypox (MPV), which both serve as models for human smallpox infection. The studies were conducted with the assistance of researchers representing: The U.S. Army Medical Research Institute of Infectious Disease...

Viroblock SA Reports a 99% Boost of Efficacy of Facemasks Against H5N1

...ology (VCCD Tech) potentially inactivates all families and strains of enveloped viruses, like human, avian and swine Influenzas, SARS, AIDS, Ebola and smallpox viruses. VCCD Tech uses a mechanism of action that greatly limits the development of any viral resistance. The test involved flowing air contam...

Aethlon Medical Confirms Hemopurifier(R) Is a Treatment Candidate Against Swine Flu Virus

...rd Flu), the reconstructed 1918 influenza virus (r1918), West Nile virus (WNV), and Vaccinia and Monkeypox (MPV), which both serve as models for human smallpox infection. The studies were conducted with the assistance of researchers representing: The U.S. Army Medical Research Institute of Infectious Disease...

Aethlon Medical Announces Engagement of RedChip Companies to Initiate Investor and Media Relations Programs

...rd Flu), the reconstructed 1918 influenza virus (r1918), West Nile virus (WNV), and Vaccinia and Monkeypox (MPV), which both serve as models for human smallpox infection. The studies were conducted with the assistance of researchers representing: The U.S. Army Medical Research Institute of Infectious Diseases...

Dr. Larry Brilliant Joins Jeff Skoll to Combat Global Challenges

... with the World Health Organization in eradicating smallpox from Asia. He was the founding executive director ... that led the successful World Health Organization smallpox eradication program in India and South Asia. He la...s authored two books, including The Management of smallpox Eradication in India , and dozens of scientific ar...

Aethlon Medical Announces CEO Interview and Corporate Presentation Available Online

...rd Flu), the reconstructed 1918 influenza virus (r1918), West Nile virus (WNV), and Vaccinia and Monkeypox (MPV), which both serve as models for human smallpox infection. The studies were conducted with the assistance of researchers representing: The U.S. Army Medical Research Institute of Infectious Diseases...

Oklahoma State University researchers make breakthrough against poxviruses

... Stillwater, Okla. smallpox has a nasty history throughout the world. Caused by poxviruses, smallpox is one of the few disease-causing agents against w...first step towards a pharmaceutical medication for smallpox and the emerging human monkeypox. The human imm...

Immunology Center will continue to drive standard methods, better science

...on and cancer, researchers said. The resulting sophistication in understanding of the human immune system, and of how it responds to influenza, HIV or smallpox for instance, will guide the more precise design of near-future vaccines. Since its founding four years ago, the RHIC has proven that it can drive ...

America's 5000 Fastest-Growing Private Companies Revealed

...on-site services for employers and schools include onsite clinics for Flu, Meningitis, and more. Passport Health has provided anthrax vaccinations and smallpox vaccination training and has worked with the US military, Post Office, and Federal employees and currently runs a 24/7 immunization call center for th...

Study of ancient and modern plagues finds common features

...ey have no pre-existing immunity. This last factor played a key role in the smallpox epidemic that afflicted the Aztecs of 16th century Mexico. smallpox had ravaged European communities for centuries, but until the Spanish arriv...

Effective health messages may yield vaccine compliance among ER workers

...o vaccinate 500,000 healthcare workers against the smallpox virus, which theoretically could be used in a biot...;� the importance of various aspects of the smallpox vaccination in four separate scenarios: Today, with no smallpox outbreak4; if another terrorist attack happened in...

Smallpox Drug May Protect Against Common Cold

...y organs TUESDAY, May 20 (HealthDay News) -- An investigational smallpox drug may also protect against adenovirus, which causes upper respiratory in...ropyl-cidofovir (CMX001) -- is currently being developed to protect against smallpox or monkeypox, and as an antiviral agent in transplant patients. The Sain...

1 in 4 U.S. Toddlers Improperly Vaccinated

...death," he said. "Kids these days, and probably most adults, don't even known what an iron lung is -- and that's because of immunization." So far, smallpox has been completely eradicated from the planet thanks to immunizations, while great gains have been made with measles and polio. "People just need...

JCI online early table of contents: April 8, 2008

...jci.org/article.php?id=32878 VIROLOGY A pox on TLR9: the immune molecule TLR9 is crucial to prevent lethal poxvirus infection in mice smallpox is caused by infection with variola virus, a member of a family of viruses known as poxviruses. New data, generated by Hubertus Hochrein and colleague...

MIT's PANTHER sensor quickly detects pathogens

... CAMBRIDGE, Mass.--Researchers at MIT Lincoln Laboratory have developed a powerful sensor that can detect airborne pathogens such as anthrax and smallpox in less than three minutes. The new device, called PANTHER (for PAthogen Notification for THreatening Environmental Releases), represents a signifi...

Nanoemulsion vaccines show increasing promise

...d able to produce a strong immune response against smallpox and HIV in two new studies. The results build o...very diverse materials. We used whole virus in the smallpox vaccine. In the HIV vaccine, we used a single prot...agents and hepatitis B. Potential for a better smallpox vaccine The...

Who found some new mechanisms of HBV virulence?

...uble stranded circle. When made fully double stranded, this genome carries about 3000 base pairs, compared to 200 kilo base pairs of the genome of the smallpox virus. These 3000 base pairs encode an envelope protein, a core protein, a polymerase essential for virus replication and a very special X protein, na...

Researchers discover new battleground for viruses and immune cells

...led the T cells with a fluorescent marker, injected them back into the mice, and then infected the animals with vaccinia virus, the virus used to make smallpox vaccine, engineered to express a brilliantly colored protein. Using a multiphoton microscope, a highly specialized microscope that enables scient...

American Chemical Society's Weekly PressPac -- Jan. 30, 2008

...eypox is caused by a virus closely-related to smallpox. Naturally occurring smallpox has been eradicated worldwide thanks to a vaccine that has occasional serio... virus (MPV) and by the vaccinia virus (VV), which is the basis for current smallpox vaccines. The researchers identified nine proteins that were specific to MP...

Researchers uncover more about how poxviruses evade the immune system

...on about a key protein that allows viruses such as smallpox to replicate and wreak havoc on the immune system....nd rheumatoid arthritis. Of all the poxviruses, smallpox in particular has played a gruesome role in human ... million deaths in the 20th century alone. Though smallpox was declared officially eradicated in 1979, many e...

Columbus Carried Syphilis From New World to Europe, Study Suggests

... contacts between Europeans and Native Americans," Harper said. "As far as diseases go, it seemed like a one-way street: Europeans brought measles and smallpox (to the Indians). But this is an example of disease going the other way. That seems kind of fair." The findings are published in the Jan. 15 issue ...

Smallpox vaccine alternative identified

...iveness of a potential alternative to the existing smallpox vaccine that can replace the current biodefense st...esponse in human and animal studies as the current smallpox vaccine, Dryvax. The study is part of a national e... an effective and safer vaccine to the public. smallpox was declared eradicated worldwide in 1980; the las...

A Major Gift of Art and History: U-M Receives 45 Significant Medical Paintings From Pfizer

...rtifacts and locations intently. Thom's subjects range from the ancient Greek temples of Asclepius, the demigod of medicine, to the first use of a smallpox vaccine by Edward Jenner, to the founding of the American Medical Association, and the discovery of X-rays by Wilhelm Roentgen. His commission cam...
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