Sequence in Medical News

Arizona researchers to sequence West African rice strain

A $1.5 million grant from the National Science Foundation will allow University of Arizona researchers to unlock the genetic code of West African cultivated rice and along the way to gain knowledge that could help commercial rice strains to better withstand dwindling resources, a changing climate...

New MR sequence helps radiologists more accurately evaluate abnormalities of the uterus and ovaries

A new MR imaging sequence, T2-weighted BLADE, used to image the female pelvis improves image quality and helps radiologists make a more accurate diagnosis, according to a study performed at the University of Maryland School of Medicine in Baltimore, MD. A total of 26 patients were imaged usi...

Scientists From 25 Countries Sequence Cow Genome

Could lead to better breeding techniques, shed light on human genome THURSDAY, April 23 (HealthDay News) -- A consortium of more than 300 researchers in 25 countries has succeeded in sequencing the entire genome of the placid, farm-dwelling cow. The feat has implications for underst...

Genome sequence of lancelet shows how genes quadrupled during vertebrate evolution

Berkeley The newly sequenced genome of a dainty, quill-like sea creature called a lancelet provides the best evidence yet that vertebrates evolved over the past 550 million years through a four-fold duplication of the genes of more primitive ancestors. The late geneticist Susumu Ohno argued in...

Researchers Publish Genome Sequence for Duck-Billed Platypus

One of the few mammals that lays eggs offers clues to evolution of all mammalian genes WEDNESDAY, May 7 (HealthDay News) -- An international team of scientists has published the first analysis of the genome sequence of the duck-billed platypus, one of the few mammals that lays eggs. ...

Gene sequence that can make half of us fatter is discovered

A gene sequence linked to an expanding waist line, weight gain and a tendency to develop type 2 diabetes has been discovered as part of a study published today in the journal Nature Genetics. The study also shows that the gene sequence is significantly more common in those with Indian Asian th...

Molecule Disrupts DNA Sequence in Ewing's Sarcoma

Finding could yield first targeted therapy for the rare disease, researchers say MONDAY, April 14 (HealthDay News) -- A molecule that disrupts the oncogene that causes Ewing's sarcoma has been identified by Georgetown University Medical Center researchers. Ewing's sarcoma is a rar...

Panacea Pharmaceuticals Announces Selection of PAN-622 - A Fully Human Sequence Monoclonal Antibody Against HAAH - As Its Lead Cancer Therapeutic Product

GAITHERSBURG, Md., Dec. 5 /PRNewswire/ -- Panacea Pharmaceuticals, Inc. announced today the selection of PAN-622 -- a fully human sequence monoclonal antibody against HAAH -- as its lead cancer therapeutic product. Developed in collaboration with the Massachusetts Institute of Technology, PAN-...

Photo: Scientists Complete Genome Sequence of Fungus Responsible for Dandruff, Skin Disorders

Research Findings to Impact Human Health, Agricultural Science CINCINNATI, Nov. 5 /PRNewswire-USNewswire/ -- Today, scientists from P&G Beauty announced that they successfully sequenced the complete genome for Malassezia globosa (M. globosa), a naturally occurring fungus responsible for the ...

Intradigm Announces Issuance of RNA Interference (RNAi) Patent Covering Potent siRNA Sequence

First Patent to be Issued from Among Intradigm's Large Collection of Pending siRNA Sequence Patents PALO ALTO, Calif., May 19 /PRNewswire/ -- Intradigm Corporation, a leading developer of targeted, systemic RNA interference (RNAi) therapeutics, today announced the issuance of United States pa...

Scientists Map Genome Sequence Dengue Mosquito

Scientists have completed the first draft of the genome sequence of Aedes aegypti mosquito, thereby moving one step further towards the development of new strategies to prevent and control yellow fever and dengue fever. The genome sequencing was done by researchers from 24 universities an...

Babies with Cleft Conditions, Pierre Robin Sequence May Need Extended Treatment for Poor Feeding Skills

A new study looking at the feeding skills of newborns with cleft conditions found that the prevalence of poor feeding steadily decreased within one year//, but that longer treatment may prove necessary for those with Pierre Robin sequence (PRS) or a syndrome. The study is published in the latest is...

The Bovine DNA Sequence Unplugged

Scientists have achieved a very important milestone in the mapping of the bovine genome, which will make it possible to enhance the health and aid better disease// control in cattle. This research is slated to benefit the beef and diary industry immensely. Scientists firmed up on a sequence o...

NHGRI Aims To Sequence Primate Genomes

The National Human Genome Research Institute (NHGRI) a part of National Institutes of Health (NIH) has announced that it would be sequencing the genome of Northern// white-cheeked gibbon (Nomascus leucogenys). The main aim is to sequence the genome of primates along the evolutionary tree that will ...

New Technique Enables Better Nursing Of Robin Sequence Infants

A considerable improvement in the oral feeding habits of infants with breathing problems was observed in less than 11 days following institution of feeding facilitating techniques. // The only option for such infant’s had been the use of a feeding tube. Prolonged use of this was however was ass...

Identification Of Gene Sequence To Promote Growth Of New Arteries

A Research headed by the vascular surgeon Rajabrata Sarkar, MD, PhD, at the San Francisco VA Medical Center has unraveled the genetic mechanism that helps in the growth of new arteries // . He demonstrated in mice that the MMP2 gene is the key factor for the development of new arteries especially w...

Human Complexity Can Be Attributed To Regulatory Sequence

Joseph M. Miano, Ph.D associate professor within the Cardiovascular Research Institute at the University of Rochester Medical Center said that // small regulatory DNA sequences control the genes and their functions. The researchers scanned the vast human DNA code to reveal 60 genes controlled...

New Research Suggests Most Are Willing to Make Tradeoffs and Would Embrace Comprehensive Health Care Reform

... public's assumptions and definitions differ from those of experts. sequence the conversation. People have to work through certain questions before they are ready to consider others. The report suggests a sequence of questions that leaders and others can use to structure the conversation ...

Scientists Decode HIV Genome

...would help unlock additional roles of RNA genomes that are important to the life cycle of HIV and other viruses. "One approach is to change the RNA sequence and see if the virus notices," co-author Ron Swanstrom, a professor of microbiology and immunology, said in the release. "If it doesn't grow as well w...

Silenced genes as a warning sign of blood cancer

... methyl labeling ranges among the epigenetic changes that do not change the sequence of DNA building blocks. Such labels are found particularly often in genes w...ed into proteins. Unlike genetic mutations, which permanently change the sequence of the DNA building blocks, all epigenetic mutations are reversible and, th...

Why anorexic patients cling to their eating disorder

...ent a test that measured their capacity for flexible behavior modification of recently learned behavior. In this test, the subjects were shown a rapid sequence of various geometric shapes and asked to match them. After one test run, the matching principle was changed. "In this study, we confirmed that ano...

GeneGo Awarded NIH Grant to Develop Pharmacogenomics Software Suite

...ecifically designed for the study of mutations and sequence heterogeneity in human genes and their controlling...regions, as well as the biological consequences of sequence variations on disease susceptibility and drug resp...ful tools for researchers to be able to link these sequence variations to the specific mechanisms and biologic...

Teaming Up to Tackle a Deadly Cancer

... demonstrated that patients benefited significantly from this therapy. The foundation has also funded the launch of the Chordoma Genome Project to sequence the chordoma genome to identify the mutations that drive the tumor. "This should lead to a lot of answers," Sommer said, adding that the findings will...

Fluorescent probes may permit monitoring of chemotherapy effectiveness, Stanford study shows

...he Stanford University School of Medicine have found a way to do just that, by lighting up cells as they die. Apoptosis is a carefully orchestrated sequence of intracellular events that leads to the cell's death. "The cell takes itself apart in a finite series of steps," said Matthew Bogyo, PhD, associate ...

The GenoMEL project identifies a new region of the genome associated with the risk of melanoma

...sana Puig and Dr. Josep Malvehy are the only Spanish authors of this article. Single-nucleotide polymorphisms (SNPs) are small variations in the sequence of nucleotides that make up DNA and can be associated with many genetic diseases. The study published in Nature Genetics performs an exhaustive sear...

Gene's novel role may provide key to treating liver and neurodegenerative diseases

...pedes an important pathway to apoptosis, which is mediated by a key protein called Fas. Using their mouse model, the scientists elucidated part of the sequence of molecular events that regulates Fas-mediated apoptosis. They found that FAIM functioned as a key switch in the Fas cell death circuit, which cou...

Cancer Researchers Link DICER1 Gene Mutation to Rare Childhood Cancer

... grow quickly, setting the stage for additional genetic mutations in cells that then become cancerous. Hill's team will now focus on demonstrating the sequence of events that result from loss of DICER1. Only 50 or 60 cases of PPB are diagnosed worldwide each year. The cancer presents as cysts in early s...

Sleep May Be Essential for Long-Term Memory

...trisynaptic circuits were disabled, researchers reported. "Our conclusion is that the trisynaptic pathway-mediated replay of the hippocampal memory sequence during sleep plays a crucial role in the formation of a long-term memory," said Tonegawa. More information Learn more about this and other stu...

Standard IQ Test May Undervalue People With Autism

...essive Matrices, a 60-item test of abstract reasoning ability. The questions, which are highly visual in nature, ask participants to identify the next sequence of a larger pattern or the missing segment of complex geometric shapes. During the test, MRIs indicated that people with autism showed more activit...

Lung Enzyme Both Friend and Foe

...quentially unique. "Humans, mice, rats and rabbits all have that special sequence and structure in MMP-12, but not in other MMPs," Houghton said. The stud... to penicillin." The researchers plan to investigate whether the special sequence and structure in MMP-12 can kill viruses and fungi. More information ...

TGen and USC researchers find genetic markers to help fight diabetes

...r variants that predict response to TZDs, TGen researchers performed a genome-wide analysis of 115,352 single nucleotide polymorphisms, or SNPs (a DNA sequence variation within the more than 3 billion base pairs in the human genome). In addition, the scientists also systematically screened 28 key genes involv...

Enigma Diagnostics Announces Patent On Real-Time Monitoring of Amplification Reactions Upheld In Entirety Following Opposition From BD at European Patent Office

...ostics by the Secretary of State for Defence. The technology involves the use of a thermostable endonuclease to cut a probe that recognises a specific sequence in the target amplification product. The system may be applied to a wide variety of molecular diagnostic applications including the rapid detection of...

Mayo Genomic Discovery: Protecting Kidney Function During Heart Failure

...The Mayo investigators discovered an alternative splicing (AS) of BNP in messenger RNA (produced by the same gene). When they shortened the amino acid sequence of ASBNP for testing, they found that it had the same therapeutic benefits as BNP, but without the side effects to blood pressure. Positive impacts in...

Lethality of H1N1 Influenza Virus Increasing According to Latest Replikin Analysis of Virus Peptide Genomic Data

...obal outbreak of H1N1 is increasing in its capacity for lethality. The new sequence data on PubMed of the past two weeks through June 10, 2009 showed an increa... lethality. Since the software also permitted the automated analysis of all sequence data available on PubMed for all previous years, it was noted that this is ...

Ovarian Cancer Breakthrough Heralds New Era of Treatment

...he beginning of a new era of cancer genomics, in which the complete genetic sequence of cancers and the mutations that cause them can be identified, researchers...ples from across Canada and around the world. In the past, analyzing the sequence of a tumor was a laborious process, and most studies could only look at on...

Fast pandemic detection tool ready to fight flu

... Velocity11. The system will be able to automatically determine the genetic sequence of viruses such as influenza hundreds of times faster than any other method...wer. The new genotyping system features two robots and the ability to fully sequence 10,000 or more influenza viruses per year. This makes it much faster and mo...

New accurate diagnostic test for swine H1N1 influenza using RT-PCR technology

...specifically amplifies and characterizes the viral genetic material, enabling rapid detection of new viral strains as they evolve. Using these genetic sequence data and making minor alterations to the PCR primers used in the assay, the test could be easily modified to detect newly emerging viral variants, inc...

CEL-SCI Expands Testing of Its Vaccine to Determine Efficacy Against More Virulent Strain of H1N1 Swine and Other Influenza Viruses

... novel T-cell modulation platform technology that enables CEL-SCI to design and synthesize proprietary immunogens. Any disease for which an antigenic sequence has been identified, such as infectious, parasitic, malignant or autoimmune diseases and allergies, are potential therapeutic or preventive sites for ...

Sangamo BioSciences Presents Positive Phase 2 ZFP Therapeutic Data at ADA 2009

...g Zinc Finger DNA-binding Protein (ZFP) Technology for therapeutic gene regulation and modification. By engineering ZFPs that recognize a specific DNA sequence Sangamo has created ZFP transcription factors (ZFP TF(TM)) that can control gene expression and, consequently, cell function. Sangamo is also developi...

Study Finds Multitude of Bacteria on Human Skin

...me Project, an offspring of the Human Genome Project, which mapped all the genes in the body. The same techniques used to go through the human genetic sequence now can be applied to bacteria, Segre said. The diversity found as the investigators sequenced bacteria found in moist sites (inside the nose, the ...