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New Scientific Evidence Suggests Humans Resistant to Phthalate Effect on Lab Rodents

Sharpe et al. Study Finds Dose High Enough to Cause Adverse Effect in Rats and Mice Has No Effect in Male Marmosets ARLINGTON, Va., June 25 /PRNewswire-USNewswire/ -- The American Chemistry Council (ACC) today announced that strong new evidence has emerged that phthalates may not affect the ...

ChemGenex's omacetaxine may provide first viable treatment option for highly resistant form of CML

MELBOURNE, Australia, and MENLO PARK, California U.S.A. (June 1st, 2009) ChemGenex Pharmaceuticals Limited (ChemGenex) (ASX:CXS) announced that the latest data from its pivotal study of omacetaxine in patients with T315I-positive chronic myeloid leukemia (CML) was the subject of an oral presentat...

Telik Presents Results at ASCO From ASSIST-5 Trial of TELCYTA in Platinum Refractory and Resistant Ovarian Cancer

PALO ALTO, Calif., May 31 /PRNewswire-FirstCall/ -- Telik, Inc. (Nasdaq: TELK ) today announced presentation at the 45th Annual Meeting of the American Society of Clinical Oncology (ASCO) in Orlando, Florida, of results from the ASSIST-5 Phase 3 randomized, multinational study of TELCYTA(...

New HIV Drug May Help Those Resistant to Therapy

Study in monkeys finds that it reduces replication of the virus,,,, WEDNESDAY, April 1 (HealthDay News) -- An investigational drug might help people with HIV who don't respond to standard anti-retroviral therapy, a new study suggests. Currently, the "gold standard" treatment for HI...

Cepheid Announces European Release of First On-Demand Molecular Pre-Surgical Screening Test for Simultaneous Detection of Methicillin-Sensitive and Resistant S. aureus

World's Most Comprehensive On-Demand HAI Test Portfolio Now Available to European Hospitals SUNNYVALE, Calif., March 31 /PRNewswire-FirstCall/ -- Cepheid (Nasdaq: CPHD ) today announced the release of the Xpert(R) MRSA/SA Nasal test as a European CE IVD Mark product under the European Direc...

Castrate resistant prostate cancer: New therapeutic approaches

Today Dr. Martin Gleave of the Vancouver Prostate Centre in Canada gave a lecture about new approaches to treat castrate-resistant prostate cancer (CRCP) during the 24th Annual Congress of the European Association of Urology in Stockholm, Sweden. "If we look at the way kidney cancer treatment ...

Antibiotic Combo Fights Resistant TB

2 FDA-approved drugs inhibit both normal and virulent strains, study finds THURSDAY, Feb. 26 (HealthDay News) -- Combination treatment with two FDA-approved drugs shows promise in treating extensively drug-resistant tuberculosis (XDR-TB), a U.S. study shows. In laboratory tests, re...

Study shows rise in antibiotic resistant pediatric head and neck infections

Highlights Prevalence of antibiotic-resistant head and neck infections is increasing. There is growing concern in the medical community about an epidemic of community acquired antibiotic resistant infections. Clinicians must be judicious in prescribing antibiotics. ATLANTA A re...

A Study In This Month's Journal Of Nervous And Mental Disease Reveals Hope For Recovery From Suicidal Thinking And Treatment Resistant Mental Illness

STOCKBRIDGE, Mass., Jan. 15 /PRNewswire-USNewswire/ -- In 1992, the Austen Riggs Center, a small, not-for-profit psychiatric hospital and residential treatment center in Western Massachusetts, began to follow 226 admitted patients in a multidimensional follow-along study that asked, among others...

Common Flu Strain Resistant to Popular Antiviral Drug

But other medications are available that work, CDC officials stress THURSDAY, Jan. 8 (HealthDay News) -- The most common strain of flu this season is resistant to the popular antiviral drug Tamiflu, but government health officials said Thursday there is no reason to panic. The fact ...

Combining targeted therapy drugs may treat previously resistant tumors

A team of cancer researchers from several Boston academic medical centers has discovered a potential treatment for a group of tumors that have resisted previous targeted therapy approaches. In their Nature Medicine report, which is receiving early online release, investigators from Dana-Farber ...

New method to overcome multiple drug resistant diseases developed by Stanford researchers

Many drugs once considered Charles Atlases of the pharmaceutical realm have been reduced to the therapeutic equivalent of 97-pound weaklings as the diseases they once dispatched with ease have developed resistance to them. The problem is well documented for antibiotics, although not confined to...

Scientists Create Mice Resistant to Obesity

Research with a brain chemical might lead to drug treatments for humans SUNDAY, Aug. 10 (HealthDay News) -- Researchers have developed a strain of mice resistant to diet-induced obesity. The findings could one day lead to possible drug treatments for obesity in people. They also sh...

HIV Drug Might Spur Resistant Strains of Virus

Used during breast-feeding to prevent mom-to-baby transmission, nevirapine could have downside, study finds TUESDAY, Aug. 5 (HealthDay News) -- The drug nevirapine -- widely used in developing countries to prevent transmission of HIV from mothers to babies -- persists in the breast mi...

Methadone Kills Resistant Leukemia Cells

Low doses of drug used to treat opioid addiction worked without toxic effects, study finds FRIDAY, Aug. 1 (HealthDay News) -- Methadone, a drug used to break addiction to heroin and other opioid drugs, appears to be a potent killer of leukemia cells, a new study finds. "Methadone ki...

Overweight, insulin resistant women at greater risk of advanced breast cancer diagnosis, says study

Women who have risk factors commonly associated with Type 2 diabetes also have much greater odds of being diagnosed with an advanced breast cancer, according to research to be presented today (Tuesday 8 July 2008). University of Melbourne researcher Dr Anne Cust was a key collaborator on an int...

Future hope for patients with breast cancers resistant to tamoxifen

Researchers have found a new family of therapeutic agents that interferes with the ability of estrogen to stimulate the growth of breast cancer cells. The results of the new study will be presented by Nicole Patterson at The Endocrine Society's 90th Annual Meeting in San Francisco. The cell-ba...

How advanced prostate cancer becomes resistant to androgen-deprivation therapy

SEATTLE For the past 70 years the treatment of choice for advanced, metastatic prostate cancer has been androgen-deprivation therapy. That is, the suppression of circulating testosterone the hormone that fuels prostate-cancer growth via surgical castration (orchiectomy) or medical castration wi...

Combination of 2 novel anti-cancer agents may help fight CML resistant to current therapy

Virginia Commonwealth University Massey Cancer Center researchers have identified that a combination of novel anti-cancer compounds is able to kill chronic myelogenous leukemia cells previously resistant to conventional forms of therapy. Chronic myelogenous leukemia, or CML, is a cancer of the ...

Drug compound leads to death of ovarian cancer cells resistant to chemotherapy

In a discovery that may be useful for maintaining remission in chemo-resistant ovarian cancer, Yale scientists report that pre-clinical studies have shown the drug compound NV-128 can induce the death of ovarian cancer cells by halting the activation of a protein pathway called mTOR. Gil Mor, M...

New Guidelines Tackle Treatment of Resistant Hypertension

Multi-drug regimens, dose timing, adherence to therapy all matter, heart association says MONDAY, April 7 (HealthDay News) -- Lifestyle factors and medication recommendations are among the topics covered in the guidelines for treating resistant hypertension released Monday by the Ameri...

Research could put penicillin back in battle against antibiotic resistant bugs that kill millions

Research led by the University of Warwick has uncovered exactly how the bacterium Streptococcus pneumoniae has become resistant to the antibiotic penicillin. The same research could also open up MRSA to attack by penicillin and help create a library of designer antibiotics to use against a range o...

New study finds resistant organisms at core of soft contact lens corneal infections

In 2006, Bausch & Lomb withdrew its ReNu with MoistureLoc contact lens solution because a high proportion of corneal infections were associated with it. Now in a new study from University Hospitals Case Medical Center, researchers show that these infections were fueled and made resistant to treat...

Stem cells make bone marrow cancer resistant to treatment

Scientists at the Johns Hopkins Kimmel Cancer Center say they have evidence that cancer stem cells for multiple myeloma share many properties with normal stem cells and have multiple ways of resisting chemotherapy and other treatments. A report on the evidence, published in the Jan. 1 issue of ...

Cancer cell line developed that is resistant to new cancer therapy

A cancer cell line that is resistant to one of the newest classes of cancer treatments has been developed by researchers who already are using it to determine what else to give patients when this happens. The ultimate goal is to be able to understand how cancer cells develop resistance and to h...

New drug candidate knocks out resistant form of chronic myeloid leukemia

PORTLAND, Ore. Oregon Health & Science University Cancer Institute researchers have found a new, experimental drug candidate it to be effective against a highly resistant mutation in chronic myeloid leukemia (CML). This drug candidate could build on the legacy of Gleevec, which has been the ...

Ear infection superbug discovered to be resistant to all pediatric antibiotics

Researchers have discovered a strain of bacteria resistant to all approved drugs used to fight ear infections in children, according to an article to be published tomorrow in the Journal of the American Medical Association (JAMA). A pair of pediatricians discovered the strain because it is their s...

MU researchers studying model to learn why certain cancers become resistant to drugs

COLUMBIA, Mo. Resistance to chemotherapy treatments can be the worst news a cancer patient ever receives. A pair of researchers at the University of Missouri-Columbia is working steadfastly to learn why some tumors eventually build a tolerance to the common chemotherapy drug cisplatin, in hopes o...

Genetic Mutation That Makes Common Cancers Resistant to Drugs Identified

Researchers from Eli Lilly and Company and the Phoenix-based Translational Genomics Research Institute (TGen) have identified the genetic mutation that may alter tumour cell proliferation, and make them resistant to certain types of therapies. The researchers say that they found a recurr...

First Genetically Engineered Maize Resistant to Maize Streak Virus Produced in S. Africa

Scientists at the University of Cape Town, South Africa, and colleagues at the South African seed company, PANNAR Pty Ltd, have reportedly developed a resistant variety of maize that could alleviate both food shortages and promote genetically engineered (GE) foods in Africa. The MSV-resist...

Plan to Contain Drug Resistant TB Launched-WHO

The WHO warned on Friday that the new drug resistant TB could create an "apocalyptic scenario" if it not contained. It has already affected more than 30,000 people.. The new plan from WHO and the Stop TB Partnership outlines actions they say are needed to slow the spread of multi-drug resis...

American Who Exposed Air Passengers to Drug Resistant TB Quarantined

Drug-resistant tuberculosis may be the disease generally identified with the third world and the poor. But it is spreading its tentacles everywhere. US authorities fear that an American might have exposed fellow air passengers on two transatlantic flights this month to the potentially lethal disea...

New TB Vaccines in Could Protect Against All Drug Resistant Strains

New tuberculosis (TB) vaccines in development have the potential to provide protection against all strains of TB, including multidrug-resistant (MDR) and extensively drug- resistant (XDR) TB , Dr. Jerald C. Sadoff, president and CEO of the Aeras Global TB Vaccine Foundation, said here today at the ...

Four Gay Men Carrying Highly Multiple-drug Resistant Strain of HIV Reported

It’s a discovery that may well be giving HIV health care workers sleepless nights.// There has been an accounting of four gay men having a highly drug resistant form of HIV in King County, Seattle. This form of AIDS progresses much more rapidly than others and is likewise more difficult to t...

Scientists Come Up With A Powerful Weapon To Fight Drug Resistant Bacteria

The War between scientists and bacteria has been going on for sometime now. Sometimes it appears the scientists have an upper hand when they come up with a new anti-biotic that// successfully conquers the particular strain of bacteria, and when the celebrations are still going on, different resista...

Breast Cancer Stem Cells Appear Resistant to Radiation Therapy

Breast cancer stem cells, seem to be obstinate, as scientists have discovered, as they portray a resistance to radiation therapy. As a result, they are extremely// difficult to annihilate. In fact radiation could even increase the growth of these stem cells, warn researchers from the University of ...

New drugs for resistant forms of TB

An international meeting on breathing disorders in Paris discussed the ongoing research on development of new drugs against tuberculosis. //There is a need to revamp the more than a century old test that takes a long time for detection and drugs to which the strains of TB have become resistant. ...

New Bird Flu Virus Resistant To Vaccine: Study

A new strain of the killer H5N1 avian flu virus that had emerged in early 2006 in China and southeast // Asia appeared to be resistant to the vaccination programme and might even be aided by it. It might have begun the third wave of transmission of H5N1 avian flu and could potentially spread ...

Threat posed by highly resistant strains of TB

An article published online this week in The Lancet warns that tuberculosis (TB) programs and HIV programs may face a threat from tuberculosis strains //that are resistant to both first-line and second-line drugs. The study conducted by a team of researchers from the United States and South A...

Partial-match cell transplants for kids with resistant leukemia

Children with most resistant leukemia can be treated with a superior method of blood stem cell transplantations, when regular treatment fails, as showed by the clinicians at the St. Jude Children's Research Hospital. // The St. Jude technique allows blood stem cells to come from parents or un...
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