Resistance

New antibiotic already developing resistance

An anti biotic, just a year old, which was developed to fight resistant bacteria, is already becoming stale as the bacteria are showing signs of resistance. The drug linezolid is used to treat Enterococcus faecium (E. faecium) infections that are resistant to the old standby antibiotic vancomycin. The hope has been that the new drug would help tackle the growing problem of vancomycin-res...

Early puberty more resistance

A recent study has found that early puberty and late menopause have better chances of surviving a broken hip.Broken hips are a common symptom of osteoporosis, or brittle bone disease.// Most women who sustain a hip fracture survive, but sometimes death can occur as a result. Researchers in Norway sought to investigate the impact a woman's reproductive variables, such as age when her p...

Training with weights helps building resistance

According to researchers, many people have believed that training with free weights - dumb bells and bar bells is best kept for youthful people.// According to Bruce Craig, of the Human Performance Laboratory at Atlanta University, men and women well past retirement age have much to gain from resistance training. Weight work increases your mobility and improves reaction time - both of w...

Link between birth weight and Insulin Resistance

According to researchers in England, a baby's birth weight is connected to the mother's insulin resistance in late adulthood. The study also shows women with the lightest and heaviest offspring had the highest risk of developing diabetes.// More than 4,100 women ages between 62 and 75 years participated in the study. Researchers found, as birth weight increased every 2.2 lbs, women had...

Easier Methods Required to Screen Insulin Resistance

Insulin resistance is a major medical problem often leading to diabetes and cardiovascular disease. Being overweight greatly increases the odds someone will be insulin //resistant, but not all overweight or obese people are afflicted. The insulin suppression test used to identify insulin resistance, however, it is too difficult to administer to large numbers of people. Researchers have...

Easier Methods Required to Screen Insulin Resistance

Insulin resistance is a major medical problem often leading to diabetes and cardiovascular disease. Being overweight greatly increases the odds someone will be insulin // resistant, but not all overweight or obese people are afflicted. The insulin suppression test used to identify insulin resistance, however, it is too difficult to administer to large numbers of people. Researchers hav...

Insulin Resistance Linked To Difference In Gender

Type 2 diabetes used to be considered an adult disease, but now more children are being diagnosed with type 2 diabetes.// Research has shown girls are affected more than boys. Now, a new study shows sex-linked genes may explain this difference between girls and boys being diagnosed with type 2 diabetes. Researchers in the United Kingdom are conducting a study which aims to establish whi...

Adopting Easier Methods To Screen Insulin Resistance

Insulin resistance is a major medical problem often leading to diabetes and cardiovascular disease. Being overweight greatly increases the odds // someone will be insulin resistant, but not all overweight or obese people are afflicted. The insulin suppression test used to identify insulin resistance, however, it is too difficult to administer to large numbers of people. Researchers have...

Drug Resistance Questioned in Patients With Chronic Sinusitis

Patients with chronic sinus infections, known as chronic rhinosinusitis, do not appear to develop resistance to antibiotics taken over // long periods of time, shows new research. Researchers say guidelines recommend four to six weeks of antibiotics as a first-line treatment for chronic sinus infections before surgery is considered. However, they say little data exist on the appropriate...

Understanding Insulin Resistance

Based on findings of a recent study researchers say girls are affected more than boys. Researchers say sex-linked // genes may explain this difference between girls and boys being diagnosed with type 2 diabetes. Researchers are in the process of conducting a study which aims to establish which children are insulin-resistant and why. The study included 307 healthy children 4 or 5 years ol...

Scientists Unveil Mechanism Behind Resistance to Severe Malaria

Scientists have discovered why some people are less prone to malaria//. The people with a specific type of hemoglobin — the oxygen-carrying molecule that gives red blood cells their color — are less prone to severe malaria. In a series of experiments, the researchers determined how hemoglobin type C impairs the ability of malaria parasites to cause disease symptoms. “This research give...

Junk Food Causes High Level Of Insulin Resistance In Children

Research involving 3,189 school children from Denmark, Estonia and Portugal// reported that children from poor families don’t necessarily have worse health compared to children from children’s of rich and better-educated parents. The results of the study were published in British Medical Journal. The results of the study challenge the results of the earlier reported results that adverse social ci...

Ways Of Tackling Antibiotic Resistance

A recent broadcast by BBC , looked into antibiotic resistance in the food chain. The report was based on the findings of the agencies laboratory which carried out the testing for levels of antibiotic resistant bacteria found in chicken. // Using these results the programme asserted various links between the use of antibiotics in farming, levels of resistant bacteria found in the chic...

Flu-Drugs Are Causing Resistance Across The World

Flu-drugs may be increasing the drug resistance across the world. According to a report // published online in the journal The Lancet, worldwide resistance to drugs used to treat influenza has increased by 12% since the mid-nineties. Adamantanes have been used to treat influenza A virus infections for more than 30 years. Previous surveillance studies have iden...

Bacteria born with drug resistance

Researchers from McMaster University has reported in the Journal Science the results of their research in which they found that the scientists screened 480 strains of Streptomyces species which is a soil bacterium and found that all the strains were multi-drug resistance //as they were tested against a battery of 21 different classes of antibiotics. The researchers were astonished by t...

Malaria May Gain Resistance To Single Drug Prescriptions

Pharmaceutical companies have been called upon to stop marketing a single treatment malarial drug, by the World Health Organization (WHO), as the parasite which causes malaria may develop a resistance to it. // Arata Kochi, director of the WHO's malaria department, said that the practice of using artemisinin, one of the most effective anti-malarials, on its own would result in the par...

Antibiotics Used In Food Animals Causes Antibiotic Resistance In People

The latest research study in Australia shows that less antibiotic used in food animals leads to less drug resistance in people. // Australia has adopted a policy of restricting antibiotic use in food-producing animals and this may be linked with lower levels of drug-resistant bacteria found in its citizens. The bacteria Campylobacter jejuni is known to be one of the leading causes of...

Global Fund Policy Encouraging Drug Resistance

WHO has warned Global Fund, the world's leading funder of treatments for infectious disease, that its current policy of Treating AIDS, Tuberculosis and Malaria// carried a risk of causing drug resistance. Kochi Arata, head of the WHO's malaria programme referring to the compliance list of drugs circulated by the Global Fund which contains advice on the malaria drug artemisinin. It has bee...

A New Anti-Cancer Drug Keeps Resistance Out

An experimental drug named Dasatinib, developed by Bristol-Myers Squibb company offers a valuable treatment against the signs and symptoms of chronic myeloid leukemia// patients than the usual drug named Gleevec. Patients, who are resistant to Gleevec drug can now be treated with dasatinib, which seems to regulate intolerance and complications of chronic myeloid leukemic patients - stu...

A Carrier Protein Associates With Human Insulin Resistance

A study reports that low blood protein levels are found to be associated with reduced insulin resistance and thus risk of diabetes// , metabolic syndrome and cardiovascular disease decreased. A protein in blood called retinol-binding protein 4 (RBP4), when reduced by the effect of modified diet and good exercise programs proved to drop the risk factors of diabetes – finding reports. <br...

Insulin Resistance: An Important Indicator of Heart Disease and Diabetes for Teens

Researchers have pointed out that Insulin resistance during adolescence is an important indicator of diabetes and heart disease in adulthood.// Obesity is indicated by a body-mass index of 30 or higher. The key factor to ward off diabetes and heart disease is to ensure that people do not gain weight in childhood and adolescence, which will certainly reduce the risks of disease during...

Heart Center at Sinai Conducts Landmark Study on Aspirin Resistance

With coronary artery disease the single leading cause of death in the western world, aspirin is used by millions of patients as a prevention and treatment regiment for this deadly disease.// In the largest study to date on the effectiveness of aspirin, researchers at Sinai Hospital of Baltimore recently demonstrated that aspirin resistance is rare, less than 5 percent, at all doses (81 mg, 162 mg...

Efforts to Check Uncontrolled use of Antibiotics and Antibiotic Resistance

Researchers from the Indiana University School of Medicine, the Regenstrief Institute, Inc. and the Richard Roudebush Veterans //Administration Medical Center have noted in a research regarding guidelines that control antibiotics and antibiotic resistance in hospitals, that the hospitals which adhere to national guide lines which have been laid down to control the use of antibiotics report consid...

Bird Flu Virus Shows Moderate Resistance to Tamiflu

According to a latest WHO report, the H5N1 virus showed reasonable resistance to Tamiflu, an antiviral, in two Egyptians who died last month due to bird flu.// This caused anxiety in the medical community. The report also states that the mutated virus strain called as 294S was first found in Vietnam in 2005. The occurrence of this strain in Egypt reveals that it has spread outside Asia...

Secret to AIDS Resistance Is in the Blood

The absence of a specific marker in the blood and tissues of certain monkeys may be part of the key to understanding how they can be infected// for years with SIV, the primate version of HIV, and never develop AIDS, according to research published by Tulane University pathologist Ivona Pandrea in the scientific journal Blood. Pandrea compared the blood, lymph nodes and intestines of f...

Widely Used Hepatitis B Drug Spurs HIV Drug Resistance

A Johns Hopkins study has proven false established medical practice that an antiretroviral drug widely used to treat hepatitis B liver infections was safe to use// on its own in patients co-infected with HIV. Their findings demonstrate that treatment with entecavir leads to cross-resistance to other antiviral drugs used to treat the AIDS virus. “Our results show that entecavir is no d...

Scientists Explore Ways to Reduce Insulin Resistance by ‘handcuffing’ Gens

Scientists from the renowned Salk Institute for Biological Studies, have discovered that silencing a gene for a peptide involved// in insulin secretion will not only reduce insulin resistance, in animal models, it will also help avoid the drawbacks associated with a high calorie diet. The peptide in question is ucocortin 3. This was discovered after ucocortin 2. Both are peptides pro...

Tuberculosis Drug Resistance 'alarming' in India

An alarming 20 percent of the people availing re-treatment of tuberculosis are at the risk// of developing drug resistance in India. According to a leading global health advocacy, India witness nearly 1.8 million fresh cases every year. On the eve of the World TB Day, March 24, the Global Health Advocates (GHA), a Switzerland-based non-profit body, said that TB drug resistance is beco...

Aspirin Resistance Is Higher in Diabetics

Aspirin has long been the industry standard for the prevention and treatment of heart attacks.// However, for the more than 20 million Americans living with diabetes, the standard dose of aspirin might not provide adequate protection against future heart attacks. Researchers have recently demonstrated that aspirin resistance is higher in diabetics with coronary artery disease (CAD) than in non-di...

Study Suggests Some Drug Resistance to Influenza B Medications

Use of certain common antiviral drugs during a recent influenza B epidemic in Japan showed the development of viruses with partial resistance to the drugs//, according to a study. Two antiviral drugs, zanamivir and oseltamivir, which are a type of drugs known as neuraminidase inhibitors, have been effective against influenza and are used extensively. There has been documented evidence...

Resistance Already Emerging in First Months of Treatment Despite Viral Load Decline

The emergence of drug resistance is already detectable in the first months of HIV treatment even if viral load is falling, and is especially pronounced// in people who experience slower viral load declines, a small, intensive German study has found. As selection of drug-resistant virus correlated significantly with the length of time until viral load became undetectable, the researche...

Resistance to Anti-HIV Drugs in Uganda Developed Due to Drug Supply Problems

Some HIV-infected patients in Uganda who self-paid for their antiretroviral medications experienced interruptions in drug supply due to either financial// demands or supply logistical disruptions. These treatment interruptions led to the development of resistance to antiretroviral medications in patients. These findings by a team led by researchers at the Infectious Diseases Institute...

New Mechanism Identified for Resistance to Targeted Lung Cancer Drugs

An international research team, led by investigators from the Massachusetts General Hospital (MGH) Cancer Center and Dana-Farber Cancer Institute (DFCI), has found// a new way that some lung tumors become resistant to treatment with targeted therapy drugs like Iressa and Tarceva. Their report, which will appear in the journal Science and is receiving early online release, describes a totally new...

HIV Drug Resistance can Be Identified by Genome Sequencing

Undetectable drug-resistant forms of HIV have been identified by Yale School of Medicine researcher Michael Kozal, M.D., using an innovative genome sequencing technology that quickly detects rare viral mutations. Kozal, associate professor of medicine at Yale and senior author of the retrospective study that used samples from an earlier clinical trial, presented the findings today at...

Cytokine Resistance Contributes to Pathology of Type 2 Diabetes

A new study by University of Illinois researchers describes how an impaired anti-inflammatory response plays a role in the pathology of type 2 diabetes . Published in the Journal of Immunology, the study focused on a number of cytokines, protein signals that bind to specific receptors on cells and set off a cascade of biochemical reactions within the cell. Interleukins...

Combination Therapy Reduces Tumor Resistance to Radiation

Radiation is used to treat a variety of tumors and the response of tumors to radiation is dependent on endothelial cell death, which in turn limits oxygen delivery to the tumor, causing hypoxia and tumor cell death. Recently, radiation-induced hypoxia was shown to trigger tumor resistance to radiation via the activation of new blood vessel formation (angiogenesis) through molecules known as HIF...

New Insights into Antimalarial Drug Resistance

Researchers at Georgetown University Medical Center say they are moving closer to understanding why the most lethal form of human malaria has become resistant to drug treatment in the past three decades. They have been able to artificially construct, and then express in yeast, a protozoan gene that contributes to such resistance. The gene they laboriously constructed over a two-yea...

AutoGenomics Addresses TB Crisis With a Genetic Drug Resistance Test

CARLSBAD, Calif., "In light of the recent news event where a passenger with extensive drug resistant tuberculosis (XDR-TB) flew on multiple airline flights and potentially infected other passengers, the need for rapid identification of MTB and assessment of drug resistance is critical to control of the spread of the disease" said Dr. Nani Dattagupta, Chief Scientific Officer of AutoGenomics. <br...

Adults Who Are Overweight and Obese Experience a Lowered Response to Resistance Training

A new study in The Journal of Strength and Conditioning Research suggests that adults who are overweight and obese experience a lowered response to resistance training when compared to normal weight adults. The study compared the response to a supervised upper arm, unilateral resistance training program in healthy, young adults who are overweight or obese to the response of normal...

Resistance to Scientific Explanations By Children and Adults

Childrens resistance to scientific explanations is based in what they know and how much they trust the person who told them, Yale researchers report in Science this month. The resistance will continue into adulthood if the scientific claims are challenged and if the nonscientific alternative is based in common sense and championed by people who are thought to be reliable and trustw...