Renal

Renal problem alleviated

The cognitive problems that can occur in patients with chronic renal failure might be alleviated by certain antioxidants, say US researchers. Scientists at the University of California, Irvine, found that rodent models of chronic renal failure had higher levels of nitrotyrosine, a marker of oxidative damage caused by the interaction of oxygen free radicals with nitric oxide, in areas...

Increase in renal problems

The cognitive problems that can occur in patients with chronic renal failure might be alleviated by certain antioxidants, say US researchers. Scientists at the University of California, Irvine, found that rodent models of chronic renal failure had higher levels of nitrotyrosine,// a marker of oxidative damage caused by the interaction of oxygen free radicals with nitric oxide, in areas of their c...

Effect of drug on Renal Cancer

According to the researchers of University of Houston, a new study shows thalidomide at higher doses in kidney cancer patients is associated with manageable side effects.// The study also shows long-term use may lead to neuropathy.They examined the effects of escalating thalidomide doses in kidney cancer patients. Patients received oral thalidomide starting at 200 mg per day. Researchers increase...

Renal problem increased

The cognitive problems that can occur in patients with chronic renal failure might be alleviated by certain antioxidants, say US researchers. Scientists at the University of California, Irvine, found that rodent models of chronic renal failure// had higher levels of nitrotyrosine, a marker of oxidative damage caused by the interaction of oxygen free radicals with nitric oxide, in areas of their c...

Drug Spironolactone Provides Renal And Cardioprotection In Diabetic Patients

Professor Kaspar Rossing and his colleagues from the Steno Diabetes Center, Denmark has found that supplementation of Spironolactone drug to diabetes patients taking //antihypertensive drugs, reduced the chances of developing kidney failure and reduced blood pressure and albumin protein in urine of these patients. Diabetes patients with high blood pressure are more prone to kidney dis...

Acute Toxicity Of Nano-Scale Zinc Powder: Severe Renal Damage And Anemia

Zinc finds wide use in brass, bronze, die casting metal, alloys, rubber, and paints, etc. In recent years, nanoscale metal powders, because of their unique properties, are being widely used //in the traditional industries, such as dyes, paints, medical diagnosis, sunscreens and cosmetics. Nano Zn powder is used as highly reactive catalyst in organic hydrogen reaction, automobile tail gas disposal...

A Novel Method Of Detection Of High Nuclear Grade Localized Renal Cell Carcinoma

Elective nephron-sparing surgery (NSS) is considered appropriate for small renal cell carcinoma (RCC) tumors; however, it is still difficult to detect high nuclear grade RCC preoperatively. // Although no specific tumor markers have been identified for RCC, immunosuppressive acidic protein (IAP) is a variable predictor of lymph node and distant metastasis in patients with RCC. At present...

Negative Impact Of Hepatitis C Infection In Renal Transplant Recipients

Recent research demonstrates that hepatitis C virus infection is a bad prognostic indicator for patient and graft survival duration in renal transplant recipients//. Hepatitis C virus (HCV) infection is reported in 3%-64% of renal allograft recipients; the prevalence depends on the geographic area. Infections are the commonest cause of death in renal transplant recipients. Researchers...

Clinical Renal Trails Do Not Have Sufficient Women Participants

New findings that are being presented during the American Society of Nephrology’s 38th Annual Meeting and Scientific Exposition in Philadelphia, Pennsylvania, say that women are not being adequately represented during medical trials // more specifically renal trials. Through analyses of the recently conducted renal trials showed this shortcoming. It is theorized that this may be the r...

Adrenal Suppression not predicted by inhaled corticosteroids

It is proved beyond doubt that asthma is affected beneficially by long-term treatment with inhaled corticosteroids (ICS) in childhood//. Although there is a lot of side affects that are associated with it. Which include adrenal suppression and growth deceleration; continue to be of concern to physicians that treat asthmatic children. The main researchers were Kostas N. Pri...

Sunitinib a Promising Agent for Treatment of Renal Cell Cancer

Sunitinib has been found to be an effective agent for treating metastatic renal cell cancer, a disease for which no effective treatment options are available so far//. There is an urgent need for more active agents for the treatment of metastatic (spread of cancer from point of origin to another part of the body) renal cell carcinoma (RCC). The 5-year survival rate for metastatic RCC...

Genetic Link to Adrenal Tumor Revealed

Recent research has revealed that a genetic deficiency of an important enzyme can result in a rare tumor of the adrenal glands appears //. The enzyme is one of a class of enzymes involved in halting a cell's response to hormones and appears to stop cells from dividing. The study, published in Nature Genetics, was conducted by researchers in NIH's National Institute of Child Health and...

Adrenaline Associated With Adventurers Risk Taking

Andrew Murr and his friend David Thacher had once taken a camping trip to Quinault Rain Forest, which is the wettest forest in the U.S and which may lead to fatal accidents// . It is reported that the night temperatures fell to freezing and the mudslides could even throw their tent over 3 inches of mud. We have heard about Kit DesLauriers skiing down Mount Everest recently and one can'...

New Biotech Drugs to Aid in Renal Cell Carcinoma Treatment

Two biotech drugs produced by Bayer AG, Pfizer and Onyx pharmaceuticals are astounding doctors with their effects on decreasing the progression// of metastatic kidney cancer. The drugs, sunitinib (marketed under brand name Sutent) and sorafenib (brand name Nexavar) have been found to delay the progression of renal cell carcinoma by 3 to 6 months. Renal cell carcinoma is th...

Stock of Adrenaline Runs Out, in New Zealand Hospitals

New Zealand: A crucial drug, ‘Adrenaline’, known to save the day during life-threatening allergic reactions// and heart attacks, is going out of stock, causing panic amongst medics. Wellington-based Mayne Pharma, New Zealand's sole supplier is facing a problem with its German manufacturers. This has led to the interruption in the supply of this drug to New Zealand. Hospita...

MRI Contrast Agent Linked to Complication in Renal Patients

A "mysterious" condition called nephrogenic systemic fibrosis (NSF)— which occurs only in patients with advanced kidney disease—is strongly// related to use of gadolinium dyes for MRI scans, reports a study in the March Clinical Journal of the American Society of Nephrology. An accompanying editorial identifies specific groups of patients in whom gadolinium exposure should be avoided,...

Targeting the Adrenal Gland Could Be Key Against Heart Failure

Scientists have staved off heart failure in animals by using gene therapy to shut down the adrenal gland’s excessive// output of fight or flight hormones such as epinephrine and norepinephrine. By blocking GRK2, an important regulatory enzyme, they cut the hormone production that forces the heart to pump too hard, leading to heart failure. Such a novel approach – targeting the adrenal gland in ad...

Biocon Unveils Renal Therapies for Kidney Disorders

India's premier biotechnology firm Biocon Ltd Thursday announced the launch of renal therapy products for treating kidney disorders and reducing// the risk of such disease. As the leading producer of immuno-suppressants in the subcontinent, the company has set up a nephrology division to market the new products -- Renodapt (Mycophenolate Mofeti), Tacrograf (Tacrolimus), Cyclophil Me (...

Renal Transplantation in Children Younger Than 6 Years Old

Garcia, et al reported their experience with renal transplantation in 38 children //(40 transplant), ages 1-5 years over a 16 year period. Demographics as well as patient and graft survivals were all reported. The mean age at transplantation was 3.3 ± 1.3 years and the mean weight was 14 kilograms with a range of 5.7-25 kg. The population consisted of 92.5% Caucasian, 7.5% African Brazilian. The...

New Balloon Catheter Available Worldwide for Carotid and Renal Angioplasty

Today at the 61st Annual Meeting of the Society for Vascular Surgery, Cordis Endovascular, division of Cordis Corporation, announced the worldwide launch of the Cordis AVIATOR (TM) Plus Balloon Dilatation Catheter for use in angioplasty procedures for patients with carotid and or renal artery blockages. AVIATOR(TM) Plus combines a unique high-pressure expansion and low profile .014 inch rapid exc...

Pazopanib Shows Positive in Advanced Renal Carcinoma, Ovarian Cancer and Soft Tissue Sarcoma

CHICAGO, GlaxoSmithKline today announced results from ongoing Phase II studies of pazopanib in advanced or metastatic renal cell carcinoma (RCC), ovarian cancer and soft tissue sarcoma (STS). These trials were presented at the 43rd Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago. The results observed in these trials with pazopanib support further investigations. <br...