RNA in Medical News

Quark Pharmaceuticals Announces the Presentation of Data Indicating Potential Utility of QPI-1002 in Chronic Kidney Disease at the RNA Interference Summit

FREMONT, Calif., June 9 /PRNewswire/ -- Quark Pharmaceuticals, Inc., a development-stage pharmaceutical company discovering and developing novel RNA interference (RNAi)-based therapeutics, today announced that Bruce A. Molitoris, M.D., Director, Division of Nephrology and Professor of Medicine, I...

Intradigm Announces Issuance of RNA Interference (RNAi) Patent Covering Potent siRNA Sequence

First Patent to be Issued from Among Intradigm's Large Collection of Pending siRNA Sequence Patents PALO ALTO, Calif., May 19 /PRNewswire/ -- Intradigm Corporation, a leading developer of targeted, systemic RNA interference (RNAi) therapeutics, today announced the issuance of United States pa...

Study first to show that RNA interference can facilitate vaccine development

Athens, Ga. - Pharmaceutical companies and universities are racing to develop drugs that use the gene silencing mechanism known as RNA interference to treat a host of diseases. Now, a new study opens up an entirely new possibility for this powerful tool: Researchers at the University of Georgia ha...

Scientists at CSHL uncover new RNA processing mechanism and a new class of small RNAs

A very small fraction of our genetic material--about 2%-- performs the crucial task scientists once thought was the sole purpose of the genome: to serve as a blueprint for the production of proteins, the molecules that make cells work and sustain life. This 2% of human DNA is converted into interm...

Caltech engineers build first-ever multi-input 'plug-and-play' synthetic RNA device

PASADENA, Calif.--Engineers from the California Institute of Technology (Caltech) have created a "plug-and-play" synthetic RNA device--a sort of eminently customizable biological computer--that is capable of taking in and responding to more than one biological or environmental signal at a time. ...

The 'febit science lounge' presents: Webinar About Role of Non-Protein-Coding RNA in Human Genome Set for 11 a.m. EDT on June 12

'The human genome as an RNA machine' with Prof. John Mattick with Institute for Molecular Bioscience at University of Queensland, Australia LEXINGTON, Mass. and HEIDELBERG, Germany, June 5 /PRNewswire/ -- febit holding gmbh today unveiled plans for the first of a series of educational Webinar...

Short RNA strand helps exposed skin cells protect body from bacteria, dehydration and even cancer

Every minute, 30,000 of our outermost skin cells die so that we can live. When they do, new cells migrate from the inner layer of the skin to the surface of it, where they form a tough protective barrier. In a series of elegant experiments in mice, researchers at Rockefeller University have now di...

The RNA drug revolution -- a new approach to gene therapy

New Rochelle, NY, January 23, 2008RNA interference (RNAi) represents an innovative new strategy for using small RNA molecules to silence specific genes associated with disease processes, and a series of review articles describing the state-of-the-art and potential therapeutic applications of RNAi ...

Tiny RNA Molecules Control Breast Cancer's Spread

Finding could lead to better prognosis, treatments, researchers say WEDNESDAY, Jan. 9 (HealthDay News) -- Researchers have zeroed in on a handful of tiny ribonucleic acid (RNA) molecules that seem to control whether or not breast cancer travels to the lung and bone. These "microRNAs...

MCG selected as RNA laboratory for worldwide diabetes study

The Medical College of Georgia Center for Biotechnology and Genomic Medicine has been selected to isolate RNA and DNA from the blood of thousands of children involved in a worldwide study of the causes of type 1 diabetes. MCG also is enrolling children in the mammoth study that will eventually ...

SuperArray Bioscience Corporation Licenses RNA Interference Patent From The Carnegie Institution

FREDERICK, Md, Nov. 30 /PRNewswire/ -- SuperArray Bioscience Corporation announced today that it has entered into a RNA Interference (RNAi) license agreement with The Carnegie Institution. Under the agreement, SuperArray Bioscience Corporation will develop, manufacture and distribute worldwide...

New class of RNA molecules may be important in human cancer

COLUMBUS, Ohio Research here shows that an obscure form of RNA, part of the protein-making machinery in all cells, might play an important role in human cancer. These ultraconserved non-coding RNAs (UCRs) have been considered junk by some researchers, but a new report in the September issue o...

Role of RNA in Checking the Development of Tumors

Scientists at the University of Oxford have discovered a unique way to switch off a gene involved in cell division.// The system is a form of RNA, a chemical found in cell nuclei, whose role until now had remained a mystery; scientists are presently exploring this area and its role in offsetting th...

HIV RNA Level Seen As Little Value In Predicting Treatment

A study in the September 27 issue of JAMA says that initial research indicates that the HIV RNA level in untreated HIV positive patients has little or no effect on CD4 cell count decrease. //This finding may lead to conflicts in opinion as to when antiretroviral therapy must begin. Depletion o...

Toxic Strand Of RNA Causes Myotonic Muscular dystrophy

Studies have indicated that myotonic dystrophy in adults, which is the most common type of myotonic dystrophy could be due to a toxic RNA. // br> Doctors at the University of Virginia Health System have shown for the first time that by getting rid of poisonous RNA (ribonucleic acid) in muscle ce...

Non-Coding RNA Vital For Gene Activation And Protein Expression

Scientists at University of California have gained valuable insights about the differentiation of embryonic stem cells of fruit fly// , a finding that may eventually accelerate current research on stem cells and cancer. The research is a joint effort by Dr. Frank Sauer (UCR Biochemistry Profe...

Understanding the RNA binding protein and its functions inside the cell

Researchers at the University Of Pennsylvania School Of Medicine developed a new technique which will help us to understand the way RNA molecule interacts with the other molecules present in the cell.// RNA-binding proteins are special molecules that play a key role in managing some of the cell...

Scientists Decode HIV Genome

... Breakthrough finding shows virus carries huge rna genetic code WEDNESDAY, Aug. 5 (Health...carries its genetic information as single-stranded rna rather than double-stranded DNA. Information encoded in rna is more complex. The HIV...

GenVault's GenSolve(TM) Reagents Enable State-of-the-Art Genomic Analysis of Dried Blood Spots

...latform enables the extraction, preservation, recovery, and distribution of DNA at room temperature. Future systems will also accommodate proteins and rna to provide a comprehensive solution. From GenPlate to the Dynamic Archive, GenVault is continuously developing and refining best practices for DNA sam...

Isis Pharmaceuticals to Present at Canaccord Adams' 29th Annual Global Growth Conference

...is Web site within 48 hours and will be archived for a limited time. About Isis Pharmaceuticals, Inc. Isis is exploiting its expertise in rna to discover and develop novel drugs for its product pipeline and for its partners. The Company has successfully commercialized the world's first anti...

Hologic Announces Third Quarter Fiscal 2009 Operating Results

... preterm birth risk assessment, mini C-arm for extremity imaging and molecular diagnostic products including HPV and reagents for a variety of DNA and rna analysis applications. Hologic, Adiana, AEG, BioLucent, Cervista, Cytyc, MammoSite, MammoPad, NovaSure, R2, Selenia, Suros, ThinPrep and Third...

Quark Pharmaceuticals to Participate in IBC's Oligonucleotide Therapeutics: From Concept to Implementation Conference

...a development-stage pharmaceutical company discovering and developing novel rna interference (RNAi)-based therapeutics, today announced that James D. Thomp...of the field. Panelists will include Paul Burke, Ph.D., Executive Director, rna Therapeutics, Merck & Co., Inc.; Klaus Giese, Ph.D., Chief Scientific O...

Photos: One Million Patients Choose Hologic's NovaSure(R) System Over Hysterectomy

... preterm birth risk assessment, mini C-arm for extremity imaging and molecular diagnostic products including HPV and reagents for a variety of DNA and rna analysis applications. For more information, visit www.hologic.com . Forward Looking Statement Disclaimer This News Release may contain ...

Millennium Pharmaceuticals Inc./Lymphoma Research Foundation funds lymphoma research

...terized by over expression of the gene cyclin D1 due to a chromosomal translocation. A subset of MCL also expresses higher levels of a group of small rna molecules, called miR-17~92. Dr. Fu and his co-workers have found that higher expression of miR-17~92 is directly correlated with poorer patient surv...

Quark Pharmaceuticals Announces Data Indicating Potential Utility of QPI-1007 for Treatment of Glaucoma

... FREMONT, Calif., July 27 /PRNewswire/ -- Quark Pharmaceuticals, Inc., a development-stage pharmaceutical company discovering and developing novel rna interference (RNAi)-based therapeutics, today announced data suggesting that QPI-1007 prevents progressive retinal ganglion cell (RGC) loss in an incr...

Neuronal survival and axonal regrowth obtained in vitro

...to do so, they used gene therapy based on use of interfering RNA. The short rna sequences, which were made to measure, were inserted into the cytoplasm of ...cultured astrocytes using a viral therapeutic vector. Once in the cell, the rna activates mechanisms which block the synthesis of the two proteins secreted...

Webcast Alert: Isis Pharmaceuticals' Second Quarter 2009 Financial Results Conference Call

...webcast will be available for a limited time at www.isispharm.com. ABOUT ISIS PHARMACEUTICALS, INC. Isis is exploiting its expertise in rna to discover and develop novel drugs for its product pipeline and for its partners. The Company has successfully commercialized the world's first anti...

Orlando Regional Medical Center (ORMC) Implements PNA FISH(R) Tests to Help Provide Better Care for Patients with Bloodstream Infections

...ensitive and specific fluorescence in situ hybridization (FISH) assay that uses PNA (peptide nucleic acid) probes to target species specific ribosomal rna (rRNA) in live bacteria and yeast. PNA FISH tests enable microbiology labs to provide rapid and accurate identification of bloodstream pathogens, incl...

96-Week Safety and Efficacy Findings Presented for INTELENCE(TM) (etravirine) As Part of HIV Combination Therapy

...adults with non-nucleoside reverse transcriptase inhibitor (NNRTI) and protease inhibitor (PI) resistance had an undetectable viral load (<50 HIV-1 rna copies/mL) while taking INTELENCE(TM) (etravirine) tablets plus background regimen (BR) compared with placebo plus BR. These findings were presented ...

New HIV Study Shows That Large Numbers of Women and People of Color Can Be Successfully Enrolled In U.S. HIV Clinical Studies

...agents, is indicated for the treatment of human immunodeficiency virus (HIV-1) infection. This indication is based on analyses of plasma HIV rna levels and CD4+ cell counts from 2 controlled Phase 3 trials of 48 weeks duration in antiretroviral treatment-naive and treatment-experienced patients...

Study Shows a Link Between Schizophrenia & Genetic Mutations

...ink between schizophrenia and ultra-rare variants in microRNA genes on the X-chromosome has been identified. Mutations in a subset of these regulatory rna genes may strongly predispose to schizophrenia. The recently published study in PLoS ONE by the laboratories of Steve S. Sommer, MD, PhD and John J. ...

Small Molecule Might Play Big Part in Lung Cancer

...-21 and EGFR may make attractive targets for therapy, the researchers tested two experimental compounds: an antisense molecule designed to bind to the rna and essentially turn it off; and a compound called AG1478, which targets the cell's EGFR and tyrosine kinase pathway. The researchers found that t...

Scientists Reverse Muscular Dystrophy in Mice

... the overproduction of a certain type of messenger rna (mRNA) in cells, which affects muscle control and ... in the DNA translate into expanded repeats in the rna which then bind up various cellular proteins. Thes...ative Research Center. This is the first time rna has emerged as a culprit in a disease process, he ...

MO BIO Laboratories, Inc. Launches PowerFood(TM) Microbial DNA Isolation Kit

...ic acid purification procedure. For samples that do not require inhibitor removal, MO BIO's UltraClean(R) line includes optimized products for DNA and rna isolation from a variety of sample types. Also for clinical samples, the Bi O stic(TM) kits provide solutions for higher yields and purity of nucleic ...

Six Researchers to Receive Prestigious Awards from the American Society of Hematology

...edictors of survival. He further showed that each molecular subtype of cancer has its own "Achilles heel," which can be discovered by loss-of-function rna interference-based genetic screens. His work established a new paradigm for understanding the pathways of lymphomagenesis and the interactions of the ...

Hologic to Release Third Quarter Fiscal 2009 Operating Results on Monday, August 3, 2009

...essment, preterm birth risk assessment, mini C-arm for extremity imaging and molecular diagnostic products including reagents for a variety of DNA and rna analysis applications. For more information, visit www.hologic.com . Contact: Deborah R. Gordon Vice President, Investor R...

Hologic to Present at the 29th Annual Canaccord Adams Global Growth Conference

... preterm birth risk assessment, mini C-arm for extremity imaging and molecular diagnostic products including HPV and reagents for a variety of DNA and rna analysis applications. For more information, visit www.hologic.com . Contact: Deborah Gordon Vice President, Investor Re...

Stem Cells' "Suspended" State Preserved by Key Step, Scientists Report

...er of Regeneration Medicine and Stem Cell Research at UCSF. The scientists discovered the pivotal role of Chd1 by using the powerful technique of rna interference, or RNAi, to screen this gene and 40 other candidate genes. (RNAi is a naturally occurring process in which small RNAs bind to other RNAs...

International conference on reproductive science to be held in Pittsburgh July 18-22

...scientists working on the impact of obesity and reproductive health, the impact of the environment on reproductive cancers, and the potential of micro rna therapy for diseases such as diabetes and other endocrine-associated diseases. The meeting concludes Wednesday, July 22, after a morning of scientific...

New Report Just Published: World Hepatitis C Virus And Therapeutics Market Report

... Complications Due to Chronic HCV Infection II-34 Diagnosis II-34 Tests to Confirm HCV Presence II-35 HCV IgG Antibody Test II-35 HCV rna Test II-35 HCV Core Antigen EIA II-36 Genotype Tests II-36 Liver Biopsy II-36 Treatment for HCV Infection II-36 Monotherapy II-36 ...