Placebo in Medical News

Newer Blood Pressure Drug No Better Than Placebo in Preventing Stroke

Patients may need to be on telmisartan longer to see positive effect, researchers say WEDNESDAY, Aug. 27 (HealthDay News) -- The blood pressure drug telmisartan does not lower the rate of stroke, cardiovascular events or diabetes better than a placebo in patients who have had a stroke,...

Review of probiotic research finds only Bifantis can claim efficacy vs. placebo for IBS symptoms

PHILADELPHIA October 15, 2007 A new analysis of randomized controlled trials evaluating probiotics in the treatment of irritable bowel syndrome (IBS) has found that Bifantis, Bifidobacterium infantis 35624, the sole ingredient in Align (manufactured by Procter & Gamble), is the only probiotic cu...

Hip Osteoarthritis Therapy No Better Than Placebo

FDA-approved injection for knees less effective in deep joint areas, study finds FRIDAY, March 6 (HealthDay News) -- A single injection of hyaluronic acid is no more effective than a placebo in treating hip osteoarthritis (OA), a new French study finds. Hyaluronic acid (HA), a sub...

Popular alternative therapy for psoriasis performs no better than placebo

Anecdotal evidence touting the healing power of the Indian spice turmeric for psoriasis received a setback in a prospective study published this month by a leading dermatology journal stating that the low response rate of patients who ingested the active ingredient of the exotic spice was probably...

Placing a Finger on Responses to Placebo Types

The placebo effect has been a raging topic for several years, gaining momentum over the past one year with lab trials being conducted to // analyze physiological responses to them. A new study, published in the Feb1 issue of the British Medical Journal examines the perceptible effect of types of p...

Mystery Of The Placebo Effect, Yet To Be Solved

Placebo is usually given to patients who psychologically feel that they are unwell but are actually hale and healthy// . Some people are always under the notion that they are unwell and ask medicines to be prescribed by their General Practioners. But too much of medicines also lead to various...

Homeopathic preparation better than placebo in perennial allergic

A homeopathic preparation for perennial allergic rhinitis appears to be more effective than placebo. A multicenter team studied 50 patients with perennial allergic rhinitis. The subjects were randomized to receive either 30cc of a homeopathic preparation of principal inhalent allergen or placebo. I...

Common PTSD Drug is No More Effective Than Placebo

Guanfacine, a medication commonly prescribed to alleviate symptoms of post-traumatic stress disorder, is no more effective than a placebo, according to a study// led by researchers at the San Francisco VA Medical Center. “There was no benefit at all, and there were several adverse side effect...

Codeine As Useful As A Placebo

Codeine, which is used extensively in cough syrups, is actually no better than placebo or dummy drugs, according to a new study. The drug seems to deal effectively with suppressing cough, but actually does not treat it//. Manchester University researchers conducted a study on 24 patients with ...

Study Shows No Difference between Policosanol and Placebo

According to a trial result it is said that the dietary supplement policosanol is no better than a placebo. This drug is used as an alternative to reduce cholesterol.// It is made from the waxy coating on sugar cane and sometimes from beeswax, wheat germ and rice bran. The study results were publi...

Beetroot Juice May Boost Stamina

...bike. The same tests were repeated after the men drank the same amount of a placebo (blackcurrant cordial) for six days. After drinking the beetroot juice, ...r an average of 11.25 minutes -- 92 seconds longer than after consuming the placebo drink. The men also had a lower resting blood pressure after they drank the...

Steroid Can Ease Severe Sore Throat

...istant bacteria, the U.K. researchers say. For the study, Heneghan's group analyzed eight trials comparing the effectiveness of corticosteroids to placebo in adults or children with severe sore throats. In total, the studies included 743 patients, 369 of whom were children. The researchers found that ...

Arizona Pain Specialists Contend Recent Vertebroplasty Studies are Misleading: Studies Actually Show it is Effective at Reducing Pain

..."The conclusion that vertebroplasty does not help back pain is completely wrong. If you look closely at the study design, what they are calling a placebo is actually a facet injection." "These studies actually show that both treatments are effective," said Paul Lynch, MD, co-founder o...

Orexigen(R) Therapeutics Announces Second Quarter 2009 Financial Results

...least 5% of their body weight after 56 weeks, approximately three times the placebo categorical response rates of 16.4% and 17.1%, respectively (ITT, p<0.00...their body weight after 56 weeks, more than double the 18.9% of patients on placebo (p<0.001). Contrave patients also showed a 0.6% reduction in HbA1c from ...

Transcept Pharmaceuticals to Report Second Quarter 2009 Results

...t, Intermezzo (R) demonstrated a statistically significant decrease versus placebo in the time it took patients to return to sleep as measured by Latency to P...nt seen in these trials was headache (2.7 percent active versus 1.4 percent placebo in the outpatient study). The FDA has established October 30, 2009 ...

Surgery, 'Sham' Equal in Treating Compression Fracture Pain

... Injecting cement into spine no better than placebo procedure, study finds WEDNESDAY, Aug....r a "sham" surgery without cement. Those in the placebo arm went through the motions of surgery, including...e of the cement," Kallmes said. It could be the placebo effect or something as simple as the effect of the...

Kefir, a Probiotic-Rich Drink, May Benefit Specific Groups of Children

...active Kefir to use with their antibiotic tablet each day for ten days or a placebo drink, in which the probiotics were previously destroyed by heat (placebo)....that received the active Kefir, compared with 31% in the group that got the placebo or inactive Kefir. In another recent study published in the Journal...

Arena Pharmaceuticals Announces Second Quarter 2009 Financial Results and Recent Developments

...rage weight loss in this responder population was 26 pounds. Treatment with lorcaserin also resulted in highly significant improvements as compared to placebo in multiple secondary endpoints associated with cardiovascular risk. Lorcaserin was very well tolerated, did not result in increased risk of depressio...

Keryx Biopharmaceuticals Announces Agreement with FDA on a Special Protocol Assessment for Phase 3 Trial of KRX-0401 (Perifosine) in the Treatment of Multiple Myeloma

... placebo-controlled trial comparing the efficacy and safety of KRX-0401 vs. placebo when combined with bortezomib and dexamethasone. The trial, powered at 90%... (1:1), double-blind trial comparing the efficacy and safety of KRX-0401 to placebo when combined with bortezomib and dexamethasone in approximately 400 patien...

Boehringer Ingelheim to Commence Phase III Study Investigating the Role of BIBW 2992 as First-Line Treatment for Non-Small Cell Lung Cancer (NSCLC) Patients with EGFR Mutations

... 2008;27:4702-4711. (2) BIBW 2992 and BSC Versus placebo and BSC in Non-Small Cell Lung Cancer Patients Fai...ME-Lung 1: BIBF 1120 Plus Docetaxel as Compared to placebo Plus Docetaxel in 2nd Line NSCLC. Available at: ht...LUME Lung 2: BIBF 1120 Plus Pemetrexed Compared to placebo Plus Pemetrexed in 2nd Line Nonsquamous NSCLC. Ava...

Diagnostic tools and innovative therapies improve patient prognosis

...orescent and white light bronchoscopies with biopsies taken at six different standard sites. Subjects were then randomized to receive oral iloprost or placebo for six months. A second bronchoscopy and repeat biopsies were completed at the end of the treatment period. All biopsies were scored on a 1-8 scal...

Advanced targeted therapies effective as first-line treatment for lung cancer

...nged progression-free survival (PFS) over those on placebo a 29 to 31 percent reduction in risk of progressi...treated them with either 150mg/day of erlotinib or placebo after four cycles of platinum-based doublet chemot... 3. EFFICIENCY OF MAINTENANCE ERLOTINIB VERSUS placebo IN PATIENTS WITH UNRESECTABLE STAGE III NON-SMALL ...

FDA Approves INVEGA(R) SUSTENNA(TM) for the Acute and Maintenance Treatment of Schizophrenia

...STENNA to placebo. INVEGA SUSTENNA was superior to placebo in improving positive and negative syndrome scale ...ials and significantly delayed time to relapse vs. placebo in the longer-term maintenance study. The m...elapse (10% [n=15/156]) compared with those in the placebo group (34% [n=53/156]). Because maintenanc...

INVEGA(R) Approved as the First and Only Treatment for Schizoaffective Disorder

...l study (12 mg/day with option to reduce to 9 mg/day) were each superior to placebo in the PANSS. Numerical improvements in mood symptoms were also observed, a...tion to reduce to 3 mg/day), INVEGA(R) was not significantly different from placebo as measured by the PANSS. The most common adverse events (incidence ...

Clinical Trial by Licensee Does Not Meet Primary Endpoint

...patients with secondary progressive multiple sclerosis (SPMS). In addition, there were no statistically significant differences between dirucotide and placebo on the secondary endpoints of the study. Lilly and BioMS also announced that they would discontinue ongoing clinical trials and review available data...

FDA Approves TYVASO (Treprostinil) Inhalation Solution for the Treatment of Pulmonary Arterial Hypertension

...ment in six-minute walk distance over those taking placebo (p<0.0005). The safety and effectiveness in pat...n side effects (>= 10%) seen with TYVASO in the placebo controlled clinical study were cough, headache, na...n side effects (>= 10%) seen with TYVASO in the placebo controlled clinical study were cough, headache, na...

QuatRx Announces Further Positive Phase 3 Results For Ophena(TM) (Ospemifene Tablets) in Postmenopausal Vaginal Atrophy

...d will report out in late summer of this year. The latest results showed statistically significant changes from baseline to week 12 compared to placebo in four co-primary endpoints: the percentages of both parabasal cells and superficial cells in the vaginal maturation index, changes in vaginal pH (al...

Viagra Trial for Sickle Cell Lung Problems Halted

...id there was no indication that the drug is not safe in other populations. Pfizer, which makes Viagra and Revatio, provided the drug as well as the placebo for the trial. More information The U.S. National Heart, Lung and Blood Institute has more on sickle cell disease . ...

NHLBI stops study of pulmonary hypertension treatment in sickle cell patients

...esearchers found that, compared to participants on placebo (dummy pill), participants taking sildenafil (Reva...ey were randomly assigned to receive sildenafil or placebo for 16 weeks. Participants could also receive oth...es -- compared to 8 percent of participants in the placebo group. "Although these preliminary results are...

HOWARU(R) Protect Clinically Shown to Reduce the Incidence and Severity of Cold and Flu Symptoms in Children

...bination of Lactobacillus acidophilus NCFM((R)) and Bifidobacterium lactis Bi-07. The third group received a placebo. When compared to the placebo group, the groups that received the single and combination probiotic supplements reduced their fever incidence by 53% and 72.7% respectively. Their co...

Research Scientist Reports On Time-Tested Solution To Current Medical Crisis

... embrace health as any state of optimal functioning, well being, or progress, 2) publicize the power of the physician's bedside manner as a controlled placebo effect now known to cure without deadly side effects and 3) publicize the ancient suppressed methods of increasing the body's inner higher energies ne...

Human Genome Sciences Announces Second-Quarter 2009 Financial Results and Key Developments

...ENLYSTA (belimumab) met the primary efficacy endpoint of superiority versus placebo at Week 52 in BLISS-52, the first of two pivotal Phase 3 trials in patients...y well tolerated, with adverse event rates comparable between belimumab and placebo treatment groups. HGS plans a full presentation of BLISS-52 results at an a...

Quigley Corporation Announces Final Results of Quigley Pharma's Phase IIb Study

...but no statistical differences, between active and placebo groups for the primary and secondary endpoints mea...is was a double-blind, randomized, parallel-group, placebo controlled study conducted at 22 sites with 1 to 2...topically to the feet three times daily (tid) with placebo or QR-333 for 12 weeks. Number of pa...

Nexavar in Combination with Chemotherapy Shown to Extend Progression-Free Survival in Patients with Advanced Breast Cancer

...ized to receive 400 mg of oral Nexavar or matching placebo twice daily, in addition to 1000 mg/m(2) of capeci...rdless of causality was 15% for Nexavar vs. 8% for placebo and the incidence of treatment-emergent cardiac is...ts, respectively, were 45% for Nexavar vs. 32% for placebo and 38% for Nexavar and 28% for placebo. Women of ...

AcelRx Announces Perfect Performance of Handheld Component of ARX-01 Sufentanil NanoTab PCA System in a Phase 2 Study

...in patients undergoing major abdominal surgery. Both of those studies demonstrated highly significant efficacy results for the 15 mcg dose relative to placebo in reducing pain intensity over the 12-hour study periods. About Acute Post-Operative Pain Annually, approximately 8 million patients i...

New Alzheimer's Treatment Could Be on the Horizon

...trial testing IVIg as an Alzheimer's treatment is under way, also sponsored by Baxter. Participants in the trial are getting infusions of IVIg or a placebo every two weeks for 70 weeks, according to the U.S. National Institute of Health's online registry of clinical trials, www.clinicaltrials.gov. The...

96-Week Safety and Efficacy Findings Presented for INTELENCE(TM) (etravirine) As Part of HIV Combination Therapy

...tablets plus background regimen (BR) compared with placebo plus BR. These findings were presented today at t...pies/mL) compared to 36 percent of patients in the placebo arm (p<0.0001). "These data are impor...ive INTELENCE 200 mg twice daily (599 patients) or placebo (604 patients), each given in addition to a BR. F...

-Contrave(R) Obesity Research Phase 3 Program Meets Co-Primary and Key Secondary Endpoints; Exceeds FDA Efficacy Benchmark for Obesity Treatments-

...ight after 56 weeks, approximately three times the placebo categorical response rates of 16.4% and 17.1%, res...6 weeks, more than double the 18.9% of patients on placebo (p<0.001). Contrave patients also showed a 0.6...trial. Patients were randomized to receive either placebo or Contrave, BID, with a four week titration perio...

Econiche(TM) Vaccine Efficacy Summarized in July Issue of Foodborne Pathogens and Disease

...ens within three treatment regions of the feedyard. One group received two doses of vaccine (ALLVAC); a second group received two doses of adjuvant as placebo (NOVAC); and in a third group, half received two doses of vaccine, while the other half received adjuvant (HALFVAC). Fecal shedding of E. coli O157:H7...

Study Evaluating Efficacy and Safety of Two Low-dose Regimens of PREMARIN Vaginal Cream for the Treatment of Moderate to Severe Vaginal Atrophy Now Published

...g (equivalent to a low-dose of CE cream 0.3 mg) or placebo once daily (21 days on/7 days off) or twice weekly...Cream 0.5 g were significantly greater relative to placebo ( P <0.001). Results from the 12-week phase als...improved the most bothersome symptoms score versus placebo at 12 weeks ( P less than or equal to 0.001), inc...