Particle

Gene-Nanoparticle Gene Transfer Is Better Than Viral Vector Transfer System

Nanoparticles can be used in gene therapy to transfer therapeutic genes in to brain cells //and helps in studying genetic mechanism of brain diseases. Gene-nanoparticle complexes developed by scientists at the University of Buffalo, has proved to deliver therapeutic genes directly into the brains of living mice, the transfer rate is comparatively higher to transfer rates of viral vecto...

MRI with nanoparticles highly sensitive in detecting prostate cancer metastases

High-resolution MRI with magnetic nanoparticles is highly sensitive in detecting clinically occult lymph-node metastases in prostate cancer, according to a new report. In fact, routine use of this modality preoperatively could obviate many unneeded surgeries.// The nanoparticles, which are given intravenously 24 hours before scanning, work by binding to lymphatic cells. The particles only...

Gold Nanoparticles: Agents For Noninvasive Cancer Therapy

Gold nanoparticles are potential and very practical agents in therapeutic applications. Researchers from the University of California, San Francisco and Georgia Institute of Technology, writing Cancer Letters // (Available online 28 September) demonstrate the efficiency of gold nanospheres as photothermal agent by selectively delivering gold nanoparticles to oral carcinoma cells that overexpress...

Alzheimer's Can Be Slowed Down By Gold Nanoparticles

A combination of radiation and gold nanoparticles can help in slowing down the progress of Alzheimer's disease, according to a research conducted by scientists from Spain and Chile. The healthy brain // cells will not be affected by this. According to their study, to be published in the American Chemical Society's Nano Letters, the technique, a type of molecular surgery, has the potential to d...

Gold Nanoparticles Are Good Detectors Biological Toxins

Researchers at the University of East Anglia have found that gold nanoparticles are very effective detectors of biological toxins//. These particles they say reveal the presence of poisons far faster than existing techniques that often involve shipping samples back to a lab. This they hope would help in aiding investigations at crime scenes. Researchers led by Professor David Russell...

Scientists To Study Effect Of Nanoparticles On Liver

University of Edinburgh researchers will study the effect of tiny nanoparticles on the health of the liver. These nanoparticles are found in pollution// from traffic exhaust and are also used in making household goods such as paint, sunblock, food, cosmetics and clothes. The scientists will assess if these particles damage liver cells. Nanoparticles are atoms and molecules 80,000 times...

Nanoparticles and Their Damage to Liver Cells

According to the Research conducted by the scientists at the University of Edinburgh, it is understood that nanoparticles present in the air may have an adverse// effect on the liver cells. These nanoparticles are mainly found in the pollution from traffic exhaust, household goods such as paint, sunblock, food, cosmetics and clothes. Nanoparticles are atoms and molecules 80,000 times s...

Effect of Nanoparticles on Liver

Researchers at the University of Edinburgh plan to study how nanoparticles affect the liver. The scientists propose to assess whether the nanoparticles found// in pollution by traffic exhaust as well as in household goods like paint, sunblock, cosmetics, clothes and even food can damage to the cells of the liver. Nanoparticles are molecules and atoms about 80,000 times smaller than the...

Use of Nanoparticles in Sunscreen under Scrutiny

Nanotechnology is the use of particles which are very small. They are submicroscopic particles which are thought to pose a health hazard. // The petition was raised by environmental groups which asked the Food and Drug Administration (FDA) to strengthen its regulation of sunscreens that contain nano-sized titanium dioxide and zinc oxide. These particles are thought to cause inflammatory and immun...

Nano-sized inhaled particles traverse quickly from nose to brain

To understand the health implication when tiny particles in the air is inhaled, University of Rochester Medical Center scientists demonstrated that when rats inhale// , nano-sized particles quickly traverse the pathway and make it to many regions in the brain. This study is published in the August issue of Environmental Health Perspectives. There were also evident changes in gene expression, whic...

Tiny Sphere Of Nanoparticles Can Fight Cancer

Researchers have found in a preclinical trail, that siRNA packed as a tiny sphere can shrink ovarian cancer.// Researchers from the University of Texas M. D. Anderson Cancer Centre had reported in the August 15th edition of Clinical Cancer Research, that siRNA that are wrapped up in a tiny sphere infiltrate deeply into ovarian cancer tumour cells, which could thereby oppress the troub...

Hybrid Nanoparticles for Multimodal Medical Imaging

Since X-rays were discovered more than a century ago, triggering a revolution in medical imaging, clinicians have sought more powerful ways to "see" into the human body.// Now, with a $1.1 million grant from the John R. Oishei Foundation, researchers in the University at Buffalo's Institute for Lasers, Photonics and Biophotonics are turning their expertise in nanomedicine to the devel...

Nanoparticles Used by Researchers to Attack Brain Tumours

Treating brain tumors is traditionally difficult because of the blood-brain barrier, which prevents harmful substances from traveling //through the bloodstream into the brain. In order for chemotherapy to treat a tumor, it must penetrate this barrier. 'Thinking outside the box is a must for developing brain cancer treatments. Drugs don't get into the brain when delivered in the normal...

Inhaled Particles Increases the Risk of Lung Cancer

Exposure to certain types of inhaled particles in occupational settings and in the environment has been linked to increases in lung cancer risk. The December// Journal of Occupational and Environmental Medicine, official publication of the American College of Occupational and Environmental Medicine (ACOEM), is a special issue providing updates on particles and cancer. "A remarkable co...

Link Between Nanoparticles and Kidney Stones

Researchers at Mayo Clinic have successfully isolated nanoparticles from human kidney stones in cell cultures//and have isolated proteins, RNA and DNA that appear to be associated with nanoparticles. The findings, which appear in the December issue of the Journal of Investigative Medicine, are significant because it is one step closer in solving the mystery of whether nanoparticles ar...

Nanoparticle Uptake Zoom by Repetitive Motion

A recent research by North Carolina State University toxologists and Rice University Chemists// has highlighted the role of repetitive movements, in increasing the intake speed of nanoparticles through the skin. Vitro experiments on animal skin exposed to buckyballs formed the basis of the research. These bucky balls contained amino acids. Experiments showed that amino acid penetrated deeper and...

UC Davis Creates New Nanoparticles

Researchers at UC Davis have created a new type of nanoparticle that could be used in tests for environmental pollution// and contamination of food products, as well as for medical diagnosis. The research appears in the Feb. 7 issue of the journal Nanotechnology. Nanoparticles, according to Ian Kennedy, professor in the department of mechanical and aeronautical engineering and senior au...

Common Ingredient in Big Macs and Sodas Can Stabilize Gold Nanoparticles for Medical Use

The future of cancer detection and treatment may be in gold nanoparticles - tiny pieces of gold so small they cannot be seen by the naked eye.// The potential of gold nanoparticles has been hindered by the difficulty of making them in a stable, nontoxic form that can be injected into a patient. New research at the University of Missouri-Columbia has found that a plant extract can be used to overc...

Nanoparticle Research Offers Hope of Artificial Retinas, Prostheses

Researchers have achieved the world’s first direct electrical link between nerve cells and photovoltaic nanoparticle films. The development opens the door to// applying the unique properties of nanoparticles to the possible development of a nanoparticle-based artificial retina. Nanoparticles are artificially created bits of matter not much bigger than individual atoms. The same force...

Proteins in Microparticles Identified in Women With Preeclampsia

Proteins released by the placenta may damage blood vessels in women with preeclampsia (PE).// In PE, a complication of pregnancy linked to life-threatening increases in high blood pressure after 20 weeks of gestation, it has long been recognized that substances called "microparticles" released by the placenta damage maternal blood vessels. Researchers at Yale School of Medicine, led by S...

Nanoparticles can Damage DNA, Increase Cancer Risk

Tissue studies indicate that nanoparticles, engineered materials about a billionth of a meter in size, could damage DNA and lead to cancer, according to research// presented at the 2007 Annual Meeting of the American Association for Cancer Research. Nanoparticles are small enough to penetrate cell membranes and defenses, yet they are large enough to cause trouble by interfering with nor...

Adherence of Nanoparticles to RBC- Very Effective Drug Delivery Method

Researchers at the University of California, have discovered that attaching polymeric nanoparticles to the surface of red blood cells dramatically increases the in vivo lifetime of the nanoparticles. Polymeric nanoparticles are excellent carriers for delivering drugs. They protect drugs from degradation until they reach their target and provide sustained release of drugs. Polymeric n...

Nanoparticle in the Treatment of Glaucoma

Glaucoma is an eye disease that can cause blindness and affects millions of people worldwide. The nanoparticle can safely get past the blood-brain barrier making it an effective non-toxic tool for drug delivery, said Sudipta Seal, an engineering professor with appointments in UCFs Advanced Materials Processing and Analysis Center and the Nanoscience Technology Center. Seal and his col...

Prions Capacity can Be Aggrevated by Solid Particles

According to a new study,the rogue proteins that cause chronic wasting disease (CWD) exhibit a dramatic increase in their infectious nature when bound to common soil particles . Writing in the journal Public Library of Science (PLoS) Pathogens, a group led by University of Wisconsin-Madison prion expert Judd Aiken reports that prions, the protein agents of a family of fatal brain disor...