Blood Type May Boost Pancreatic Cancer Risk

New findings are consistent with previous research MONDAY, Aug. 3 (HealthDay News) -- Common variants of a gene that determines blood type are associated with an increased risk of pancreatic cancer, according to U.S. researchers. They studied the genomes of more than 4,300 pancreati...

Metformin May Lower Diabetics' Odds for Pancreatic Cancer

But another study finding suggests insulin treatment could boost the risk SUNDAY, Aug. 2 (HealthDay News) -- Metformin, one of the most widely used diabetes drugs, may offer patients the added benefit of lowering their odds for pancreatic cancer by 60 percent, a new study shows. But...

Smoking increases potential for metastatic pancreatic cancer

(PHILADELPHIA) Smoking has once again been implicated in the development of advanced cancer. Exposure to nicotine by way of cigarette smoking may increase the likelihood that pancreatic ductal adenocarcinoma will become metastatic, according to researchers from the Kimmel Cancer Center at Jeffers...

New drug candidate prolongs the lives of pancreatic cancer patients

Every year, 42,000 Americans are diagnosed with pancreatic cancer. Few live very long, and less than 5% are still alive five years after diagnosis. There's new hope, though, from the lab of Prof. Yoel Kloog, dean of Tel Aviv University's Faculty of Life Sciences. His drug compound Salirasib has...

Dietary fat linked to pancreatic cancer

High intake of dietary fats from red meat and dairy products was associated with an increased risk of pancreatic cancer, according to a new study published online June 26 in the Journal of the National Cancer Institute . This study was undertaken because research relating fat intake to pancre...

Eating Animal Fat May Lead to Pancreatic Cancer

Added risk is tied to red meat and dairy products, study finds,, FRIDAY, June 26 (HealthDay News) -- Fat from red meat and dairy products can increase your risk for pancreatic cancer, researchers from the U.S. National Cancer Institute report. Pancreatic cancer, which is usually fat...

Obesity While Young Boosts Pancreatic Cancer Risk

Study points to yet another reason to maintain a healthy weight,,,,,, TUESDAY, June 23 (HealthDay News) -- Being overweight or obese as a young adult increases the risk for pancreatic cancer, and obesity in middle age is linked with poorer survival from the disease, a new study finds. ...

Being overweight, obese during early adulthood associated with greater risk of pancreatic cancer

Young adults who are overweight or obese have an increased risk of pancreatic cancer, and being obese at an older age is associated with a lower overall survival rate for patients with pancreatic cancer, according to a study in the June 24 issue of JAMA . Pancreatic cancer is the fourth leadi...

Adenoviral vector specifically targeted to EphA2 receptor in pancreatic cancer cells

Pancreatic cancer is a devastating disease with poor prognosis. This warrants the development of novel therapies including gene therapy. However, clinical studies have demonstrated poor efficacy of adenoviral gene therapy because of the absence of adenoviral binding sites on pancreatic cancer cell...

Epeius Biotechnologies' Rexin-G Receives FDA Fast Track Designation for the Treatment of Pancreatic Cancer

SAN MARINO, Calif., June 17 /PRNewswire/ -- Epeius Biotechnologies ( www.epeiusbiotech.com ) announced today that its lead product, Rexin-G, has been granted Fast Track designation by the U.S. Food and Drug Administration (FDA) for use as a second-line treatment for advanced or metastatic pancre...

Jefferson researchers identify critical marker of response to gemcitabine in pancreatic cancer

(PHILADELPHIA) A protein related to aggressive cancers can actually improve the efficacy of gemcitabine at treating pancreatic cancer, according to a Priority Report in Cancer Research , published by researchers at Thomas Jefferson University. The protein, called Hu antigen R (HuR), is a stres...

Mayo Clinic finds new pathology tests double sensitivity to detect bile duct and pancreatic cancers

ROCHESTER, Minn. - Pancreatic cancer and bile duct cancer are difficult to diagnose and often fatal because they are discovered in the advanced stages of the disease. Researchers have developed new tests that double the ability to detect bile duct and pancreatic cancers, according to a Mayo Clinic...

$18 million awarded to TGen and University of Pennsylvania for pancreatic cancer research

PHOENIX, Ariz. May 27, 2009 The Translational Genomics Research Institute (TGen) and the University of Pennsylvania (Penn) will receive $18 million to research pancreatic cancer, Stand Up to Cancer (SU2C) announced today. Dr. Daniel Von Hoff, TGen's Physician-In-Chief, and Dr. Craig B. Thomps...

A New Way to Get Chemo to Pancreatic Tumors

Technique that doubles life span in mice may hold hope for people,, THURSDAY, May 21 (HealthDay News) -- Researchers are reporting that they've discovered a way to boost chemotherapy and slightly extend the lives of mice with pancreatic cancer, potentially paving the way for more effec...

Video: CREON(R) (Pancrelipase) Delayed-Release Capsules First and Only Pancreatic Enzyme Product to Receive FDA Approval Under New Guidelines

- Therapy is medically-necessary for thousands of patients with exocrine pancreatic insufficiency due to cystic fibrosis or other conditions - MARIETTA, Ga., May 1 /PRNewswire/ -- Solvay Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) approved CREON(R) ...

Popular diabetes treatment could trigger pancreatitis, pancreatic cancer

A drug widely used to treat Type 2 diabetes may have unintended effects on the pancreas that could lead to a form of low-grade pancreatitis in some patients and a greater risk of pancreatic cancer in long-term users, UCLA researchers have found. In a study published in the online edition o...

Type of connection procedure after pancreatic surgery influenced rate of pancreatic fistula

(PHILADELPHIA) After surgery to remove the head of the pancreas, invagination of the pancreas into the small intestine resulted in a lower rate of pancreatic fistula, according to researchers at the Jefferson Pancreas, Biliary and Related Cancer Center. The research was published in the Journal o...

Charring Meat May Boost Risk of Pancreatic Cancer

Increases production of carcinogens thought to invite disease, study finds TUESDAY, April 21 (HealthDay News) -- You may love your steak well done, but eating burned or charred meat may increase your risk of pancreatic cancer, a new study suggests. Researchers used data on the meat...

Mayo Clinic researchers formulate treatment combination lethal to pancreatic cancer cells

DENVER - A combination of two targeted therapies packs a powerful punch to kill pancreatic cancer cells in the laboratory, Mayo Clinic cancer researchers report. With further testing of these drugs that are from classes of pharmaceuticals already used in patients, the Mayo research may lead to new...

Research Takes Aim at Pancreatic Cancer

Discovery and testing in mice may lead to better detection and treatment SATURDAY, April 18 (HealthDay News) -- An active receptor found in certain pancreatic cancers might offer hope for treatment of the often fatal disease. A third of human pancreatic cancers looked at by Johns ...

New Drug Being Tested for Pancreatic Cancer

Lab findings show potential for use alone or in combination, scientist says,, WEDNESDAY, April 15 (HealthDay News) -- An experimental drug appeared to reduce pancreatic cancer growth in laboratory tests, according to researchers from the drug's maker, Amgen. Called AMG 479, the drug...

Experimental insulin-like growth factor receptor inhibitor reduced pancreatic cancer growth

PHILADELPHIA Researchers at Amgen are testing a fully human monoclonal antibody that inhibits the activity of insulin-like growth factors (IGF-1 and IGF-2) and appears to reduce pancreatic cancer cells in early testing, according to a report in Molecular Cancer Therapeutics , a journal of the Am...

New technique invented to reveal pancreatic stem cells

Wanted: stems cells. Just like those absconders chased by police all over the world, everybody can tell about their good deeds but none really knows how to recognize them. Yet, as of today, thanks to a study just published in the Proceedings of the National Accademy of Sciences (PNAS) and author...

Fox Chase performs the world’s first successful ViKY robot-assisted surgery for pancreatic tumors

PHILADELPHIA (March 24, 2009)This month Fox Chase Cancer Center performed the world's first successful minimally invasive distal pancreatectomy using the ViKY system's revolutionary robotic, compact laparoscope holder. The technology, developed in France and tested on thousands of patients in Euro...

Obesity Tied to Poor Pancreatic Cancer Surgery Outcomes

Study finds risk of disease recurrence, death nearly twice that of normal-weight patients WEDNESDAY, March 18 (HealthDay News) -- Obese pancreatic cancer patients are more likely than non-obese patients to have worse outcomes after surgery to treat their cancer, say U.S. researchers. ...

NCCN Announces Updates to Pancreatic Adenocarcinoma Guidelines

New updates to the NCCN Guidelines for Pancreatic Adenocarcinoma were announced on March 12 at the NCCN 14th Annual Conference. Notable additions include updates on when a laparoscopy may be beneficial to patients, clarification on diagnostic imaging protocols, and an overall emphasis on systemic ...

Study Links Blood Type and Pancreatic Cancer

Findings shed light on gene serving as marker for others involved in tumor development TUESDAY, March 10 (HealthDay News) --- People with type O blood have a much lower risk of developing pancreatic cancer, a finding that might help explain the origins of the often fatal disease. ...

'Personalized' genome sequencing reveals coding error in gene for inherited pancreatic cancer

Scientists at the Sol Goldman Pancreatic Cancer Research Center at the Johns Hopkins Kimmel Cancer Center have used "personalized genome" sequencing on an individual with a hereditary form of pancreatic cancer to locate a mutation in a gene called PALB2 that is responsible for initiating the disea...

Alcohol consumption may increase pancreatic cancer risk

PHILADELPHIA Consuming two or more drinks per day could increase a person's risk of pancreatic cancer by about 22 percent, according to data published in Cancer Epidemiology, Biomarkers and Prevention , a journal of the American Association for Cancer Research. "Our findings support multiple...

Georgetown researcher: 2 or more drinks a day may increase pancreatic cancer risk

Washington, DC -- Men and women who consume two or more alcoholic drinks a day could increase their risk of developing pancreatic cancer, according to a study published in Cancer Epidemiology, Biomarkers and Prevention , a journal of the American Association for Cancer Research. Previous stud...

U-M Researchers ID Gene Involved in Pancreatic Cancer

ATDC levels average 20-fold higher in cancerous cells ANN ARBOR, Mich., March 2 /PRNewswire-USNewswire/ -- Researchers from the University of Michigan Comprehensive Cancer Center have identified a gene that is overexpressed in 90 percent of pancreatic cancers, the most deadly type of cancer...

Optical techniques show continued promise in detecting pancreatic cancer

EVANSTON, Ill. --- Optical technology developed by a Northwestern University professor of biomedical engineering has been shown to be effective in detecting the presence of pancreatic cancer through analysis of neighboring tissue in the duodenum, according to clinical trial results published in th...

Determining risk for pancreatic cancer

In the latest clinical trial for a technique to detect pancreatic cancer, researchers found they could differentiate cells that are cancerous from those that are benign, pre-cancerous, or even early stage indicators called mucinous cystic lesions. Pancreatic cancer is dangerous to screen for, y...

The Pancreatic Cancer Action Network Celebrates 10 Years of Leadership and Service to the Pancreatic Cancer Community

EL SEGUNDO, Calif., Feb. 9 /PRNewswire/ -- The Pancreatic Cancer Action Network, the only national organization creating hope in a comprehensive way through research, patient support, community outreach and advocacy for a cure, celebrates ten years of progress and service to the pancreatic cance...

Supreme Court Justice Ginsburg Faces Tough Battle Against Pancreatic Cancer

Experts note high recurrence rate, even when malignancy is found early FRIDAY, Feb. 6 (HealthDay News) -- U.S. Supreme Court Justice Ruth Bader Ginsburg will face tough challenges following her surgery on Thursday for early-stage pancreatic cancer, experts say. At this point, it's...

Early Detection Methods for Pancreatic Cancer Urgently Needed: A Statement From the Pancreatic Cancer Action Network

EL SEGUNDO, Calif., Feb. 5 /PRNewswire/ -- The following is a statement in response to the breaking news about Supreme Court Justice Ruth Bader Ginsburg being diagnosed with pancreatic cancer from Julie Fleshman, President and CEO of the Pancreatic Cancer Action Network, the only national organiza...

Stanford study prevents pancreatic tumor growth in mice by inhibiting key protein

STANFORD, Calif. Researchers at Stanford University School of Medicine have identified a protein critical for the growth of pancreatic cancer. Blocking the expression of the protein slowed or prevented tumor growth in mice and made cultured cancer cells vulnerable to the conditions of low oxygen ...

The Pancreatic Cancer Research and Education Act Addresses the Astounding Mortality of the Fourth Leading Cause of Cancer Death in the United States

The Bill is the First Substantive Legislation that would provide Comprehensive Pancreatic Cancer Research Initiatives and Programs to Advance Scientific Progress EL SEGUNDO, Calif., Jan. 29 /PRNewswire/ -- The Pancreatic Cancer Action Network, the only national organization creating hope in a...

Nationally-Recognized Pancreatic Cancer Surgeon Develops Unique Team Approach to Improve Patient Outcomes

By the time pancreatic cancer is discovered, it is often late stage (as has been reported about actor Patrick Swayze) and survival rates are low. Dr. Aaron Chevinsky, a surgical oncologist specializing in pancreatic, liver and gastrointestinal (GI) cancers wasn't satisfied with that reality and ...

Blocking molecular pathway with whimsical name possible therapeutic target for pancreatic cancer

A possible new therapeutic target for pancreatic cancer, the most lethal form of human cancer, has been identified in the proteins whose DNA recipe comes from gene, "Seven-In-Absentia," according to researchers at the American Society for Cell Biology (ASCB) 48th Annual Meeting, Dec. 13-17, 2008 i...