AlphaRx Presents Positive Preclinical Data on Zysolin(TM) Inhalable Nanoparticles at Controlled Release Society Annual Meeting

MARKHAM, ON, July 23 /PRNewswire-FirstCall/ - AlphaRx, Inc. (OTCBB: ALRX) announced positive preclinical results which demonstrated that an inhaled tobramycin nanoparticle (Zysolin(TM)) formulation was a more effective treatment in animal models of acute Pseudomonas aeruginosa pneumonia when compa...

Making nanoparticles in artificial cells

This release is available in German . Two new construction manuals are now available for the world's smallest lamps. Based on these protocols, scientists from the Max Planck Institute of Colloids and Interfaces have tailor-made nanoparticles that can be used as position lights on cell prot...

UCF researcher's nanoparticles could someday lead to end of chemotherapy

Nanoparticles specially engineered by University of Central Florida Assistant Professor J. Manuel Perez and his colleagues could someday target and destroy tumors, sparing patients from toxic, whole-body chemotherapies. Perez and his team used a drug called Taxol for their cell culture studies,...

Novel approach estimates nanoparticles in environment

DURHAM, N.C. Without knowing how much of an industrial chemical is being produced, it is almost impossible for scientists to determine if it poses any threat to the environment or human health. Civil engineers at Duke University believe they have come up with a novel way of estimating how much...

Stanford researchers harness nanoparticles to track cancer-cell changes

STANFORD, Calif. The more dots there are, the more accurate a picture you get when you connect them. A new imaging technology could give scientists the ability to simultaneously measure as many as 100 or more distinct features in or on a single cell. In a disease such as cancer, that capability w...

Team Designs Gold Nanoparticles to Deliver Multiple Drugs

New technique might better control treatment of diseases like cancer, AIDS FRIDAY, Jan. 9 (HealthDay News) -- Massachusetts Institute of Technology (MIT) researchers have developed a drug-delivery system using gold nanoparticles that, when exposed to infrared light, can release multipl...

Gold nanoparticles for controlled drug delivery

CAMBRIDGE, Mass. -- Using tiny gold particles and infrared light, MIT researchers have developed a drug-delivery system that allows multiple drugs to be released in a controlled fashion. Such a system could one day be used to provide more control when battling diseases commonly treated with mor...

Consumers Union Urges FDA to Conduct Full Scale Safety Review of Nanoparticles in Sunscreen

Consumer Reports Test Reveals Nanoparticles Present in 4 out of 5 Sunscreens, Even When Companies Claim They Are Not YONKERS, N.Y., Oct. 30 /PRNewswire-USNewswire/ -- Consumers Union, nonprofit publisher of Consumer Reports, today released new product tests showing that 4 out of 5 sunscreens ...

Researchers use nanoparticles to deliver treatment for brain, spinal cord injuries

WEST LAFAYETTE, Ind. - Purdue University researchers have developed a method of using nanoparticles to deliver treatments to injured brain and spinal cord cells. A team led by Richard Borgens of the School of Veterinary Medicine's Center for Paralysis Research and Welden School of Biomedical En...

New disease-fighting nanoparticles look like miniature pastries

Ultra-miniature bialy-shaped particles called nanobialys because they resemble tiny versions of the flat, onion-topped rolls popular in New York City could soon be carrying medicinal compounds through patients' bloodstreams to tumors or atherosclerotic plaques. The nanobialys are an importan...

Using magenetic nanoparticles to combat cancer

Scientists at Georgia Tech have developed a potential new treatment against cancer that attaches magnetic nanoparticles to cancer cells, allowing them to be captured and carried out of the body. The treatment, which has been tested in the laboratory and will now be looked at in survival studies, ...

Iowa State University researcher looks to use nanoparticles for food safety

Ames, Iowa Byron Brehm-Stecher, assistant professor in food science and human nutrition, has some big ideas for his work with tiny particles. His latest research project will allow him to study the potential of using silver nanoparticles to improve the safety of the worlds food supply. Althoug...

Symposium to explore role nanoparticles may play in disease

BETHESDA, Md. (April 2, 2008) Two Mayo Clinic researchers who study the role nanoparticles may play in hardening of the arteries and in the formation of kidney stones, will lead a symposium on how these super-small particles may affect the bodys physiology. The symposium will take place April 8 a...

Brown chemists create cancer-detecting nanoparticles

PROVIDENCE, R.I. [Brown University] Magnetic resonance imaging (MRI) can be a doctor's best friend for detecting a tumor in the body without resorting to surgery. MRI scans use pulses of magnetic waves and gauge the return signals to identify different types of tissue in the body, distinguishing ...

Novel 3-D cell culture model shows selective tumour uptake of nanoparticles

A nanoparticle drug delivery system designed for brain tumour therapy has shown promising tumour cell selectivity in a novel cell culture model devised by scientists at The University of Nottingham. The project, conducted jointly by the Schools of Pharmacy, Biomedical Sciences and Human Developmen...

Adherence of Nanoparticles to RBC- Very Effective Drug Delivery Method

Researchers at the University of California, have discovered that attaching polymeric nanoparticles to the surface of red blood cells dramatically increases the in vivo lifetime of the nanoparticles. Polymeric nanoparticles are excellent carriers for delivering drugs. They protect drugs from...

Common Ingredient in Big Macs and Sodas Can Stabilize Gold Nanoparticles for Medical Use

The future of cancer detection and treatment may be in gold nanoparticles - tiny pieces of gold so small they cannot be seen by the naked eye.// The potential of gold nanoparticles has been hindered by the difficulty of making them in a stable, nontoxic form that can be injected into a patient. New...

Link Between Nanoparticles and Kidney Stones

Researchers at Mayo Clinic have successfully isolated nanoparticles from human kidney stones in cell cultures//and have isolated proteins, RNA and DNA that appear to be associated with nanoparticles. The findings, which appear in the December issue of the Journal of Investigative Medicine, ar...

Hybrid Nanoparticles for Multimodal Medical Imaging

Since X-rays were discovered more than a century ago, triggering a revolution in medical imaging, clinicians have sought more powerful ways to "see" into the human body.// Now, with a $1.1 million grant from the John R. Oishei Foundation, researchers in the University at Buffalo's Institute f...

Tiny Sphere Of Nanoparticles Can Fight Cancer

Researchers have found in a preclinical trail, that siRNA packed as a tiny sphere can shrink ovarian cancer.// Researchers from the University of Texas M. D. Anderson Cancer Centre had reported in the August 15th edition of Clinical Cancer Research, that siRNA that are wrapped up in a tiny sp...

Use of Nanoparticles in Sunscreen under Scrutiny

Nanotechnology is the use of particles which are very small. They are submicroscopic particles which are thought to pose a health hazard. // The petition was raised by environmental groups which asked the Food and Drug Administration (FDA) to strengthen its regulation of sunscreens that contain nan...

Effect of Nanoparticles on Liver

Researchers at the University of Edinburgh plan to study how nanoparticles affect the liver. The scientists propose to assess whether the nanoparticles found// in pollution by traffic exhaust as well as in household goods like paint, sunblock, cosmetics, clothes and even food can damage to the cell...

Scientists To Study Effect Of Nanoparticles On Liver

University of Edinburgh researchers will study the effect of tiny nanoparticles on the health of the liver. These nanoparticles are found in pollution// from traffic exhaust and are also used in making household goods such as paint, sunblock, food, cosmetics and clothes. The scientists will assess ...

Gold Nanoparticles Are Good Detectors Biological Toxins

Researchers at the University of East Anglia have found that gold nanoparticles are very effective detectors of biological toxins//. These particles they say reveal the presence of poisons far faster than existing techniques that often involve shipping samples back to a lab. This they hope would he...

MRI with nanoparticles highly sensitive in detecting prostate cancer metastases

High-resolution MRI with magnetic nanoparticles is highly sensitive in detecting clinically occult lymph-node metastases in prostate cancer, according to a new report. In fact, routine use of this modality preoperatively could obviate many unneeded surgeries.// The nanoparticles, which are give...

UC Davis Creates New Nanoparticles

Researchers at UC Davis have created a new type of nanoparticle that could be used in tests for environmental pollution// and contamination of food products, as well as for medical diagnosis. The research appears in the Feb. 7 issue of the journal Nanotechnology. Nanoparticles, according to Ian...

Alzheimer's Can Be Slowed Down By Gold Nanoparticles

A combination of radiation and gold nanoparticles can help in slowing down the progress of Alzheimer's disease, according to a research conducted by scientists from Spain and Chile. The healthy brain // cells will not be affected by this. According to their study, to be published in the American...

Nanoparticle-delivered 'Suicide' Genes Slowed Ovarian Tumor Growth

...anoparticle delivery of a DNA encoding diphtheria toxin suicide gene. These nanoparticles were injected into mice with primary or metastatic ovarian tumors. To ... grow at all, while all control tumors increased in size. Administration of nanoparticles to three different ovarian cancer mouse models prolonged lifespan by nearly...

Scientists Test New Way to Get Drugs to Cancer Cells

...ve to chemo, expert says WEDNESDAY, July 29 (HealthDay News) -- nanoparticles that can carry cancer-killing radioisotopes directly to tumors show promise, U.S. researchers report. The nanoparticles are made with liposomes, small chemical spheres made of fatty molecules tha...

Remote-control closed system invented for inserting radio-active atoms inside fullerenes

...Fatouros at VCU have funding from the National Institutes of Health's National Cancer Institute (NCI) to further develop, produce, and test fullerene nanoparticles that can identify brain tumor cells and selectively target them for radiation therapy. What if the radioactive material could also be encased in a ...

'Chemical Nose' May Sniff Out Cancer Earlier

... Rotello, of the University of Massachusetts, said in a news release. The sensors use the polymer PPE, or para-phenyleneethynylene, and three gold nanoparticles that tend to bond with the surface of chemically abnormal cells. When an abnormal cell surface grabs on to the gold nanoparticles, the PPE breaks off ...

Strides Made in Hemophilia Research

... Investigation . In the study, researchers used nanoparticles coated with hyaluron to target liver sinusoidal endothelial cells. The nanoparticles contained a therapeutic gene (Factor VIII) as well...eeks after the treatment, mice injected with these nanoparticles had Factor VIII levels that were the same as those...

Report: Asbestos Litigation Disaster for Investors Could Be Repeated With Nanotechnology Unless SEC and FASB Close Eight Major Loopholes Now Preventing Honest Disclosures

...s taking place despite evidence that the different size and surface area of nanoparticles may result in dramatically enhanced toxicity and harm to living organisms. ...f substances which could pose new and increasing risks to workers. It puts nanoparticles at the top of the list of substances from which workers need protection. ...

Scientists advance safety of nanotechnology

...identified for the first time a mechanism by which nanoparticles cause lung damage and have demonstrated that it c...ffects, particularly damage to the lungs. Although nanoparticles have been linked to lung damage, it has not been ...rticularly appealing for medicine. Scientists hope nanoparticles will be able to improve the effectiveness of drug...

Effective over-the-counter prostate cancer test kit likely in next few years

...articles, which she first mixes in a solution. The nanoparticles are engineered to attach themselves to cancer-prod...e places a drop of blood in the solution, the gold nanoparticles seek out the protein. If the protein is present, the gold nanoparticles cluster around it. Using a dynamic light-scatterin...

'Nanotechnology' May Simplify Antibiotic Treatment

... Study using nanoparticles in aerosal spray shows promise TUESDAY, May 19 (HealthDay New...died, whereas all of the mice that received just two doses of SCC22-loaded nanoparticles spaced 24 hours apart survived," investigator Dr. Carolyn L. Cannon, of the...

MIT's implantable device offers continuous cancer monitoring

...man tumor cells. The cylindrical, 5-millimeter implant contains magnetic nanoparticles coated with antibodies specific to the target molecules. Target molecules e...ble membrane, which allows target molecules to enter but keeps the magnetic nanoparticles trapped inside, is made of polycarbonate, a compound used in many plastics....

4-in-1

...egrin, a membrane protein that is anchored to metastasizing tumor cells in much higher amounts than in healthy tissue. The integrins with RGD-equipped nanoparticles are actively brought into the cell interior with their cargo intact (receptor-mediated endocytosis). The magnetic particles not only act as an aide...

Delivering Chemo Directly Into Brain Tumors Shows Promise

...time using nanoparticles. After injecting cancerous glioma cells into immunocompromised mice, researchers injected the mice with controlled-release nanoparticles that were able to carry the chemotherapy drug fluorouracil (Adrucil) to the tumor site. The University of Virginia researchers then used high-inten...

Researchers design unique method to induce immunity to certain STDs

... The researchers were able to uncover a surprising connection between vault nanoparticles and mucosal immunity. Vaults are barrel-shaped nanoscale capsules found in ...overall inflammation caused by infection," Kelly said. "We found that vault nanoparticles containing immunogenic proteins can act as 'smart adjuvants' for inducing p...