MicroRNA

MicroRNA provides new insight into birth defects

Molecules of microRNAs may be responsible for birth defects, cancer and other health problems.// The researchers of UF Genetics Institute have used genetically modified mice to see how the microRNAs are responsible for the physiological growth of animals. When the mice were grown without the microRNA molecules they grew to be malformed and with nonfunctional limbs. MicroRNA...

Cancer diagnosis easier from microRNA

MicroRNA profile analysis has been developed as a tool to diagnose cancer by scientists of Broad Institute// of MIT and Harvard. Researchers have also been able to develop a technology that will be able to test the microRNA profile through an easy and not expensive diagnostic test. MicroRNA (miRNA) are small RNA molecules that control the level of proteins made from transcribed genes....

microRNA And Its Role In Synaptic Regulation

microRNA belong to the non-coding region of the genome. They play a very important role in regulating the other gene activities like synapses. Researchers at Children's Hospital, Boston says that they are involved in the development of the nervous system.// Synapses are the junctions where the brain cells communicate with each other. This region is very important in the process of developing lea...

Role Of MicroRNAs In Angiogenesis Researched

According to recent research, MicroRNAs are fine targets for future therapies.Researchers belonging to the University of Pennsylvania School of Veterinary //Medicine have demonstrated how microRNA molecules are responsible for the growth of blood vessels in a human colon cancer model. This process, known as angiogenesis, is a result of the ravenous cancer cells using blood vessels to gorge on a...

Pair of MicroRNA Molecules Controls Major Oncogene in Most Common Leukemia

Researchers at Ohio State University have discovered that two microRNA (miRNA) molecules help control the oncogene responsible for a dangerous form of B-cell chronic// lymphocytic leukemia (B-CLL), the most common human leukemia in the world. Their findings, published in the December 15 issue of Cancer Research, demonstrate that miRNAs are emerging as powerful regulators of gene exp...

MicroRNAs Can Be Tumor Suppressors

University of Virginia researchers have discovered that microRNAs, a form of genetic material, can function as tumor suppressors// in laboratory studies. In the May 1 issue of Genes & Development, UVa researchers Drs. Yong Sun Lee and Anindya Dutta have shown that microRNAs can suppress the overexpression of a gene called HMGA2. This gene is related to creation of fatty tissue and cer...

Role of MicroRNA in Cancer Suppression Identified

Rosetta Genomics Ltd, a leading microRNA company, announced today research published in the journal Molecular Cell by scientists from the Weizmann Institute of Science and Rosetta Genomics . The findings suggest the potential for a specific, single microRNA (miR-34a) to be used as a drug candidate in cancer therapy to increase programmed cell-death (apoptosis) in the context of the potent tumor s...