Master

Protein acts as "Master Switch" that cuts off cells' Cancer-Growth machinery

A Washington University research team headed by Shrikant Anant, PhD, is mighty excited about their new discovery that was reported in the journal, Molecular Cell. They have found a "master switch" - a protein named CUBGP2(cytidine-uridine-guanosine binding protein) - that makes cancer cells self-destruct. The findings that were published// apply only to cancer cells grown in a test tube. Human st...

Researchers discover cardiac master cells

In a breakthrough finding, scientists have zeroed in on cardiac master cells that could develop into several heart tissues. //This has been discovered by different groups of researchers who have been putting their independent efforts to uncover two basic contenders. Research teams from Massachusetts General Hospital have recognized a variety of progenitor cell in mice, and have demons...

Master Switches Found for Adult Blood Stem Cells

Johns Hopkins Kimmel Cancer Center scientists have found a set of "master switches" that keep adult blood-forming stem cells in their primitive state//. Unlocking the switches' code may one day enable scientists to grow new blood cells for transplant into patients with cancer and other bone marrow disorders. The scientists located the control switches not at the gene level, but farther...

Master Regulatory Gene of Epithelial Stem Cells Identified

The skin’s ability to replace the tissue it sloughs off is controlled by a variety of genes. A new study from Harvard Medical School published// in the May 4 issue of Cell, however, identifies a "master regulator" of this regeneration process not only for skin, but for many epithelial tissues including breast, prostate, and urogenital tract. This master regulator of epithelial stem cells turns ou...

Master Regulatory Gene of Epithelial Stem Cells Identified

The skins ability to replace the tissue it sloughs off is controlled by a variety of genes. A new study from Harvard Medical School published in the May 4 issue of Cell, however, identifies a "master regulator" of this regeneration process not only for skin, but for many epithelial tissues including breast, prostate, and urogenital tract. This master regulator of epithelial stem cells turns out...

Scientists Identify "master Switch" for Brown Fat in Mice

Scientists have identified a "master switch" for the production of brown fat, a type of adipose tissue that generates heat and counters obesity caused by overeating , by conducting experiments on mice. Dr. Bruce Spiegelman of Dana-Farber Cancer Institute believes that turning up the equivalent switch in humans may be a new strategy for treating obesity. The researche...