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Malarial in Medical News

Insecticide and Repellent Combo Effective in Eliminating Malarial Mosquitoes

Researchers have revealed that combining a non-pyrethroid insecticide, propoxur, and a repellent, N,N-diethyl toluamide may prove to be an effective insecticide-repellent synergy against mosquitoes responsible for malaria transmission to humans. A combination of the two had proved to be mu...

Controlling Malarial Transmission Not Easy!

Malaria remains a dreaded human infection with around 300 million clinical cases and 3 million deaths reported every year. Controlling this disease// requires an understanding of its transmission and this involves a study of its basic reproductive number, R0. The basic reproduction number is th...

Clothes Treated with Insecticide Reduces the Risk of Malarial Infection

Wearing clothes treated with the common insecticide permethrin can reduce the chances of malarial infection by 70 percent, says a new study.// The conclusion was arrived at after Elizabeth Kimani of the African Population and Health Research Center in Nairobi and other researchers studied Soma...

Infants Malarial Risk Lowered by Preventive Measures

As a preventive measure, single dose of a common anti-malarial drug could help to reduce the risk of developing malaria in infants – study finds//. According to a new study, intermittent preventive measures of giving anti-malarial drugs to 3, 4, and 9-month old-infants lowered their risk of con...

Bahama’s Malarial Outbreak Need Contro

In Bahamas an outbreak of malarial attack has made people to be feared and need the Ministry of Health to do work to prevent its spread //. This non-endemic malarial attack has not been spread through any human or other transmissions instead it is due to a mosquito (female anopheles) in Bahamas. ...

Death Toll from Malarial Epidemic Raises To 75

According to health officials in Assam the malaria epidemic is continuing to spread with the death toll rising to 75 people and more than 300,000 others have fallen sick//. The eastern Lakhmipur district has been worst hit by the outbreak with nearly 30 deaths reported and up to 150,000 sick. ...

Older Malarial Drugs Vs New Ones

In the 2000 World Health Organization (WHO) report it was stated that Malaria affects 300 to 500 million people every year across the world and is one of the leading// cause of illness and death in the sub-Saharan African countries. A new study conducted by Dr. Hasifa Bukirwa of the Uganda Malaria ...

Chloroquine and Primaquine combination Malarial drug for resistant parasites.

Researchers from LaTrobe University of Australia have found a new combination drug for combating Plasmodium falciparum, the parasite responsible for causing malaria. They used a combination of Chloroquine and Primaquine for treatment // helps in killing P. falciparum which is resistant to Chloroqui...

A View from Rwanda: Congressional Briefing Highlights Impact of U.S. funded Anti-Malaria Programs

...ugh TRACPLUS). "We have proven in Rwanda that we can dramatically increase the number of lives saved through funding and implementing programs in malarial countries. Now, we must recognize the opportunity facing not just Rwanda, but the world: for the first time in the history of this disease, we have a...

Key to virulence protein entry into host cells discovered

...esearchers also demonstrated that the RXLR and dEER motifs could be replaced by similar targeting sequences found in effector proteins produced by the malarial parasite Plasmodium. This hints that the targets of the effectors in the soybean and human hosts may be very ancient. VBI Professor Brett Tyler rem...

Exeter engineers create new technique for malaria diagnosis

... (MOT) to detect haemozoin, a waste product of the malarial parasite, in the blood. Haemozoin crystals are wea...mical agent to detect antigens associated with the malarial parasite. One of the problems with RDTs is that th...as a matter of course. This has contributed to the malarial parasite becoming increasingly resistant to the co...

Discovery to hasten new malaria treatments, vaccines for children

...- which focused on children in remote Nigerian villages who were younger than 6 and infected with Plasmodium falciparum, the most virulent form of the malarial parasite -- has shed much-needed light on heretofore poorly understood remnants of white blood cells that have long been known to circulate in malaria...

International health experts to enlist the public in war on African malaria

...e is divided into segments and each segment has a mother trained to oversee malarial fever management in small children. Community owned resource persons (COR... tried to drive out the evil spirits they believed were causing degedege or malarial convulsions. That began to change in Tanzania thanks to a project to con...

Huge virulence gene superfamily responsible for devastating plant diseases

... for amino acids) are required for entry of the proteins into plant host cells. Similar motifs are also found in the effector proteins produced by the malarial parasite Plasmodium as it invades red blood cells. The team also detected some conserved amino acid motifs (W, Y and L) at the other end (C terminus) ...

WRAIR investigators pioneering work on an exciting new class of antimalarial compounds

...atitis E. The history of using artemisinins for malarial like conditions dates back more than 2000 years to...in Traditional Chinese Medicine as a treatment for malarial like conditions. Artemisinins are derived from th...ns are the first line of therapy for most cases of malarial illnesses. Artemisinins are also being investigat...

Supplementary approach to malaria

...nce malaria in the supplemented group (34%) compared to the placebo group (3.5%)," they explained. Supplementation also increased the time to onset of malarial symptoms and reduced the frequency of episodes. "Supplementation thus may play a key role in malaria control strategies for children in Africa," they ...

You can teach an old dog new tricks: anti-malarial prevents cancer in mice

...ommentary by Chi Dang, from Johns Hopkins University School of Medicine, Baltimore, these results complement an old epidemiology study suggesting that malarial prophylaxis with chloroquine diminished the incidence of Burkitt lymphoma. In the study, chloroquine was shown to inhibit the development of Myc-in...

JCI table of contents: Dec. 20, 2007

...ommentary by Chi Dang, from Johns Hopkins University School of Medicine, Baltimore, these results complement an old epidemiology study suggesting that malarial prophylaxis with chloroquine diminished the incidence of Burkitt lymphoma. In the study, chloroquine was shown to inhibit the development of Myc-in...

To fight disease, animals, like plants, can tolerate parasites

... They exposed five different strains of mice to malaria, and monitored the rate at which the mice lost weight and red blood cells, a common feature of malarial infections. The team found that the number of days it took for the parasites to reach peak density when parasite numbers are at a maximum differed...

Collaborative Drug Discovery, Inc. and St. Jude Children's Research Hospital Make Malaria Research Data Available to Speed Drug Development

...ude researchers are conducting a comprehensive analysis of "relevant chemical space" of these molecules, something that has never before been done for malarial drug research, Guy said. Relevant chemical space refers to the study of individual families of molecules whose members all share a similar structure t...

Genetic Factors Behind Mosquitoes Resistance to Malaria Identified

...t the genetic differences between mosquitoes resistant to or susceptible to malarial parasite manifest mainly in a region of the TEP1 protein called the warhead...s the parasite. TEP1 is a scout that finds the enemy, in this case malarial parasites, then plants a homing signal on the enemy and calls in the air st...

New Insights into Antimalarial Drug Resistance

...t with the addition of the recreated gene, PfMDR1 and its protein, they have all the biomolecular tools necessary to molecularly understand how the malarial parasite Plasmodium falciparum ( P. falciparum ), has become resistant to most of the drugs that could once destroy it. They have already described ...

Cheap Anti-malarial Drug

...have been missing out on one tablet in most cases. This has resulted in the malarial parasite developing a resistance to artesunate which is the main component in the malarial therapy. But with ASAQ, the therapy is a combination of artesunate and ...

South-East Asia Flooded With Spurious Drugs

... Vientiane, the drugs have been well disguised making it difficult for the user to find out. World Health Organization states that majority of the malarial deaths could be prevented if patients had been treated with the original drug. They also add that many of the third world countries do not have a stri...

BMC Rushes With Samples as Mystery Fever Rings Alarm Bell in Bombay

...rmine what this new virus is that apparently looks like encephalitis-fever. The reports appearing in section of Bombay media say that dengue and malarial tests on these cases came up negative. Rising to the alarm bell, the local civic authorities in Bombay have conducted a surveillance of 2500 odd...

Malaria Grips Jamaica, Nearly 160 Affected

... Jamaica – In what is thought to be the first malarial outbreak in 40 years, health officials report that an estimated 160 people have come down with malaria.// No fresh cases of malaria have been re...

New Compound for Anti-Malarial Prophylaxis

... the liver stages of human and mouse malaria. One of its semisynthetic derivatives, NCP-tazopsine, completely protected mice from a challenge with malarial parasites, and was specifically active against the liver stage, but inactive against the blood forms of the malaria parasite. This unique specifi...

The Deadly Duo – Why Malaria and HIV Coexist in Afric

...her HIV patients suffer weakened immune systems and are hence vulnerable to malarial bouts. In the light of this connection between malaria and HIV, it is...ple about the importance of abstaining from sex for eight weeks following a malarial fever, which would considerably lower HIV spread, though researcher's are n...

Malaria: The Invincible Might of a Parasite, Nestled in a 'Mite'

...ater. An infected anopheles mosquito spreads the infection by injecting the malarial parasites into the blood of a person it bites. The malarial parasites course through the bloodstream and find their way to the liver, w...

Experimental Malaria Vaccine Shows Results

...aboration, an organisation that reviews clinical trials of the vaccine, found that it protected 41 percent of volunteers in the US who were exposed to malarial mosquitoes in the lab. The RTS, S vaccine showed extremely promising results, the researchers said. The review appears in the latest issue of Th...

New method to treat malaria in pregnant women

...d out after team in Ghana and at the London School of Hygiene & Tropical Medicine (LSHTM) conducted a radomised trial. Complete elimination of the malarial parasite without any serious side effects in the women being treated was observed when they were treated either only with the drug amodiaquine or in c...

Antiretroviral Drugs: A Shot in the Arm to Fight Malaria?

...he presence of nelfinavir (Viracept), amprenavir (Agenerase) and the NNRTI nevirapine (Viramune) in thereapies did not hamper the proliferation of the malarial parasite. According to researchers, the life of the parasite is entirely dependent on the protease enzymes released by the plasmodium species, w...

A slum in Mumbai – breeding ground for disease

...en reported in 2 weeks from this area. The water source and drains in this area are contaminated with dengue transmitting Aedes aegypti mosquitoes and malarial parasites. According to the BMC health department statistics, dengue has taken 3 lives in this area; 2 in September and 1 in August. Totally, ...

Child death reduction needs five times more funds

...eatment is possible with antibiotics. According to another paper in the Lancet series, insecticide-treated bednets for protection against bites of malarial mosquitoes is available to only 3% of the children. The countries affected by malaria have not been getting sufficient funds for providing nets. "...

Malarial Parasite Hides In Placenta

...inska Institutet in Sweden and Makerere University in Uganda finds that the malarial parasite hides in the placenta of pregnant women// and this is the reason f...PNAS, can enable the development of vaccines and therapies to combat severe malarial infections. During one particular phase of its lifecycle, the parasite...

Malaria Parasite Kills Liver Cells Before Infecting Red Blood Cells

...cht Institute for Tropical Medicine in Hamburg, Germany, has found that the malarial //parasite avoids the immune system by killing the liver cell occupied by them. Till now it was known that after infecting man, malarial parasites head to the liver and then to infect the red blood cells, but it ...

Malaria a 'Near-Epidemic' in Dooars, says RSP Legislator

...that were affected by a virulent form of malaria and the affected got "very little" medical attention, he alleged. Claiming that the incidence of malarial attacks was much higher than last year, he said there was a dearth of medical and para-medical staff, as well as medicines. The RSP leader urged ...

Malaria Claimes 60 Lives In Terai, Dooars Areas

...r without blood test and confirmation of the desese. However, Health Minister Suryakanta Mishra said at the assembly in Kolkata yesterday that 40 malarial deaths were reported from three North Bengal districts of Darjeeling, Jalpaiguri and Coochbehar so far this year, with Alipurduar sub-division alone a...

Tourists Face Health Risks by Missing Vaccinations

... they should take before they left. In fact 25 per cent of such people who neither took precautions or who stopped taking them while still in a malarial area did so because they felt they would not catch the disease. Complacency also seems to be a factor governing such actions in the Britons’. 21...

Dengue In City: KMC To Appoint 30 Contract Doctors

... With dengue, viral fever and malarial attacks reported in the city areas, the Kolkata Municipal Corporation today decided to appoint 30 doctors on contract and engage para-medical staff to...
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