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Lysis in Medical News

New Treatment For Patients With Paralysis

Investigators designed a combination therapy and tested it on rats with spinal cord contusions -- the most common cause of paralysis in humans.// The combination therapy consisted of transplanted Schwann cells, which is a type of cell that insulates nerve cells, a cell messenger molecule called cyc...

Journal of Clinical Oncology Publishes TREANDA Study Demonstrating Significant Improvement in Overall Response and Progression-Free Survival in Chronic Lymphocytic Leukemia

...erious adverse reactions have been associated with TREANDA in clinical trials: myelosuppression, infections, infusion reactions and anaphylaxis, tumor lysis syndrome, skin reactions, and other malignancies. TREANDA has a unique chemical structure that is synthesized to combine an alkylating group an...

MO BIO Laboratories, Inc. Launches PowerFood(TM) Microbial DNA Isolation Kit

...athogens. Further, it is the only complete kit on the market, eliminating the need to purchase additional reagents for post-purification clean up and lysis enzymes. The PowerFood Microbial DNA Isolation Kit incorporates patented Inhibitor Removal Technology(R) (IRT) to remove PCR-inhibiting compounds ass...

Pharmacomechanical Thrombectomy Procedure Adoption to Accelerate Due to More Aggressive Treatment of Deep Vein Thrombosis, According to Millennium Research Group

...which is slated to begin recruitment in July 2009. "Firms are hoping that results of this trial will clarify the association between rapid clot lysis and the prevention of post-thrombotic syndrome in patients with proximal DVT, as well as demonstrate how PMT may have lower bleeding risks compared wi...

NeuroTherm Completes Acquisition of the Micron Epidural Catheter

...g for us to provide an epidural catheter as part of our product mix," continues Davis. The Micron Catheter is used in a procedure called Epidural lysis of Adhesions; a common interventional pain procedure used to remove scar tissue. The scar tissue which typically result from back surgery, inflame su...

Early treatment of systemic onset JIA with anakinra restores the IL-18 response

...During the six month study, numbers of NK cells slightly increased initially but remained stable throughout treatment with anakinra, although specific lysis (the death of a cell by breaking of the cellular membrane) was restored to normal within just three days. Interestingly, the NK cell response after IL...

JCI online early table of contents: April 6, 2009

... melanoma cells and suggest that NK cells could be harnessed to prevent melanoma metastasis. TITLE: NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo AUTHOR CONTACT: Francesco Colucci The Babraham Institute, Cambridge, United Kingdom. ...

New NCCN Guidelines for Primary Cutaneous B-Cell Lymphoma and Updates to NCCN Guidelines for Non-Hodgkin's Lymphomas

... on supportive care for patients with CLL. Lastly, Dr. Zelenetz touched upon a new section detailing hallmarks, symptoms, and treatment for Tumor lysis Syndrome -- a group of metabolic complications that can occur after the treatment of lymphoma. About the National Comprehensive Cancer Network ...

Data on VELCADE(R) (Bortezomib) for Injection Based Therapies to be Presented at the International Myeloma Workshop

...diac and pulmonary disorders, reversible posterior leukoencephalopathy syndrome, gastrointestinal adverse events, thrombocytopenia, neutropenia, tumor lysis syndrome and hepatic events. Women of childbearing potential should avoid becoming pregnant while being treated with VELCADE. Nursing mothers are advi...

GlaxoSmithKline and Genmab Submit Arzerra(TM) (Ofatumumab) Application to FDA for the Treatment of Advanced Stage Blood Cancer

...ase of progressive multifocal leukoencephalopathy (PML), a rare brain infection resulting in death or causing severe disability, and one case of tumor lysis syndrome were reported.(5,6) These data were presented at the 50th Annual Meeting of the American Society of Hematology (ASH) in December 2008. ...

Jennerex Clinical Trial Data with JX-594 Selected for Plenary Session Presentation at Major International Conference

... high levels in cancer cells. To enhance product efficacy, JX-594 is also engineered to express the GM-CSF protein. GM-CSF complements the cancer cell lysis work of the product candidate, leading to a cascade of events resulting in tumor necrosis, tumor vasculature shutdown and an anti-tumoral immune attac...

Publication of Clinical Results Underscores VELCADE(R) (Bortezomib) For Injection Based Therapy As a Standard of Care In Newly Diagnosed Multiple Myeloma Patients

...hy, hypotension observed throughout therapy, cardiac and pulmonary disorders, gastrointestinal adverse events, thrombocytopenia, neutropenia and tumor lysis syndrome. Women of childbearing potential should avoid becoming pregnant while being treated with VELCADE. Cases of severe sensory and motor periphera...

Millennium and Harvard Medical School Sign Cooperative Agreement for Research in Novel Field of Cancer Biology

...hy, hypotension observed throughout therapy, cardiac and pulmonary disorders, gastrointestinal adverse events, thrombocytopenia, neutropenia and tumor lysis syndrome. Women of childbearing potential should avoid becoming pregnant while being treated with VELCADE. Cases of severe sensory and motor periphera...

Millennium Submits sNDA for VELCADE(R) (Bortezomib) for Injection for the Treatment of Front-Line Multiple Myeloma

...hy, hypotension observed throughout therapy, cardiac and pulmonary disorders, gastrointestinal adverse events, thrombocytopenia, neutropenia and tumor lysis syndrome. Women of childbearing potential should avoid becoming pregnant while being treated with VELCADE. Cases of severe sensory and motor periphera...

VELCADE(R) (Bortezomib) for Injection Based Therapy Produced Significant Complete Remission Rates Pre- and Post-Transplantation in IFM Phase III Front-Line Multiple Myeloma Trial

...hy, hypotension observed throughout therapy, cardiac and pulmonary disorders, gastrointestinal adverse events, thrombocytopenia, neutropenia and tumor lysis syndrome. Women of childbearing potential should avoid becoming pregnant while being treated with VELCADE. Cases of severe sensory and motor periphe...

Phase III Trial of VELCADE(R) (Bortezomib) for Injection Showed Dramatic Fourfold Increase in Complete Remission Rates When Combined With the Most Commonly Used U.S. Regimen in Front-Line Multiple Myeloma

...hy, hypotension observed throughout therapy, cardiac and pulmonary disorders, gastrointestinal adverse events, thrombocytopenia, neutropenia and tumor lysis syndrome. Women of childbearing potential should avoid becoming pregnant while being treated with VELCADE. Cases of severe sensory and motor periphera...

Highest Reported Complete Remission Rate of 35 Percent Achieved in a Phase III Front-Line Multiple Myeloma Trial With Velcade(R) (Bortezomib) for Injection Based Therapy

...hy, hypotension observed throughout therapy, cardiac and pulmonary disorders, gastrointestinal adverse events, thrombocytopenia, neutropenia and tumor lysis syndrome. Women of childbearing potential should avoid becoming pregnant while being treated with VELCADE. Cases of severe sensory and motor periphera...

Micromet's BiTE(R) Antibodies Reveal Unique Mode of Action

.../December 2007. 2 Brandl C, Hass C, d'Argouges S et al. The effect of dexamethasone on polyclonal T cell activation and redirected target cell lysis as induced by a CD19/CD3-bispecific single-chain antibody construct. Cancer Immunol Immunother. Vol. 56:1551-1563 (2007). About BiTE(R) Antibod...

Targets on the horizon: Emerging therapies and novel targets

...cancer therapies, BiTE antibodies can recruit killer T cells for redirected lysis of tumor cells, said Roman Kischel, M.D., director of immunotherapy at Micr... expressing the antigen are attacked by T cells, and we can see target cell lysis at very low picomolar concentrations of BiTE antibodies. When MCSP-BiTE...

FDA Expands VELCADE(R) (Bortezomib) for Injection Label for Patients with Multiple Myeloma

...hy, hypotension observed throughout therapy, cardiac and pulmonary disorders, gastrointestinal adverse events, thrombocytopenia, neutropenia and tumor lysis syndrome. Women of childbearing potential should avoid becoming pregnant while being treated with VELCADE. Cases of severe sensory and motor periphera...

Severe Complications of Circumcision: An Analysis of 48 Cases

... follows: meatal stenosis in 11 (23%); urethral fistula in 5 (10.4%); partial glandular amputation in 4 (8%); and a distal urethral fistula in 3 (6%). lysis of adhesions and revisions were performed in all cases of preputio-glandular fusion. The patients with meatal stenosis underwent meatotomies. The uret...

Different Techniques Can Help Ease Chronic Pain, Return Patients’ Smile

...everything from back pain to neuropathic pain. Minimally invasive surgeries are done routinely in order to remove scar tissue – a process called lysis of adhesion – and alleviate pain in people with back or neck problems. Dedicated fluoroscopy is a non-surgical procedure that uses an X-ray syst...
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