Leukaemia in Medical News

Funding boost in fight against leukaemia

University of Manchester researchers have been awarded 1.6 million to study a group of genes identified as playing a key role in leukaemia. The grant, by Leukaemia Research, will fund work analysing a wide range of cancer-causing genes in the hope of targeting their common mechanisms of action ...

Stem cells give clues to understanding cancer and make breakthrough in childhood leukaemia

Scientists in Switzerland are uncovering new clues about how cancer cells grow and how they can be killed by studying stem cells, blank cells that have the potential to develop into fully mature or differentiated cells and other scientists in UK have made a breakthrough in understanding the caus...

Gene Mutation That Increases the Risk of Chronic Lymphocytic Leukaemia Found

Scientists at Ohio State University Comprehensive Cancer Center have discovered an inherited gene mutation that makes a person more vulnerable to chronic lymphocytic leukaemia (CLL). The study shows that the inherited mutation greatly reduces the gene's protective activity. Furthermore, a...

'Good' And 'Evil' Clones Of Acute Lymphoblastic Leukaemia cells

According to Australian scientists, there are two types of acute lymphoblastic leukaemia (ALL) cells, good and bad. //The latter type of cells are those that have a pre-existing immunity to drugs used to treat ALL, that is responsible for relapse after treatment. The discovery means that now re...

Southeast Asian Children With Leukaemia To Get New Treatment

According to experts a hospital in US is all set to use Singapore as a base in order to treat the children, who are suffering from leukaemia// , of the developing Southeast Asian countries. The breakthrough enables the bone marrow cells of the parents to be used in the transplants the children...

Mom's Stomach Bacteria Can Cause Leukaemia In Children

A bacterium strain known as Helicobacter pylori may raise the risk of childhood leukaemia, according to a new study.// Two-thirds of the world population carries H. pylori, which is responsible for ulcers. Leukaemia accounts for 25 percent of all childhood cancers worldwide. Acute lymphoblast...

New Treatment Boosts Survival Chances for Child Leukaemia

A prototype method of treating infants with a form of leukaemia boosts their chances of survival compared with the standard drug regimen, according to a paper published in next Saturday's Lancet. In general, children with acute lymphoblastic leukaemia have a good chance of survival -- abou...

New Engineered Drug Shows Promise in Treating Lymphocytic Leukaemia

A recent research has found that a new type of engineered drug may have the potential to treat chronic lymphocytic leukaemia. The study by researchers at the Ohio State University Comprehensive Cancer Center was published online in the journal Blood. The research has established t...

Artificial sweetener, Aspartame, may be the potential cause of lymphoma, leukaemia

It has been found through an animal study that Aspartame can cause lymphoma, leukaemia. The study points out that drinking four to five 20-ounce bottles of diet soda sweetened with aspartame each day would be the //cause of cancers. The study would be published in March issue of Environmental H...

Human sperm created from embryonic stem cells

...lly their own." "It will also allow scientists to study how cells involved in reproduction are affected by toxins, for example, why young boys with leukaemia who undergo chemotherapy can become infertile for life and possibly lead us to a solution." The team also believe that studying the process of for...

New data on cancer survival in Europe show more patients are cured

...dults. Survival improved over time for all the main cancer types affecting the young. The improvement was statistically significant for acute lymphoid leukaemia and central nervous system tumours in children and for non-Hodgkin lymphoma in adolescents and young adults. "Cancer survival in patients aged less...

Study finds biological clue in brain tumor development

...f young sufferers. Clinician scientists at the University's Children's Brain Tumour Research Centre, working on behalf of the Children's Cancer and leukaemia Group (CCLG), have studied the role of the WNT biological pathway in central nervous system primitive neuroectodermal tumours (CNS PNET), a type of br...

Cell Biosciences Announces First UK System Sale

... systems to life science researchers, today announced the sale of its flagship protein analysis system to The University of Manchester's Stem Cell and leukaemia Proteomics Laboratory, led by Professor Tony Whetton. Professor Whetton is a pioneer in the use of advanced proteomics technologies to understand biol...

World first treatment for leukemia being developed in Australia

... the impact of the bone marrow microenvironment on leukaemia development and progression a relatively new fiel...n the world to use the new class of drugs to treat leukaemia patients in 2010" Said Dr Wei. The leukaemia Foundation today announced that Dr Wei's and Dr Pu...

New genes involved in acute lymphoblastic leukemia play fundamental role in prognosis of the disease

...University Hospital, Kiel Campus in Germany also participated in the study and the publication of results. It is notable that acute lymphoblastic leukaemia is the most common oncological illness amongst children. It makes up 25% of all cancers amongst paediatric patients and approximately 75% of cases of ...

New study aims to reduce risk of childhood leukemia

... might affect the unborn baby's risk of developing leukaemia in childhood. Dr Cooke sees the study as a uniq...m of reducing the risk of childhood leukaemias. leukaemia is a cancer of the bone marrow and white blood cel...r cent of cases, it is still rare. Only 1 in 10 of leukaemia patients are children, accounting for 500 child di...

Genmab Announces 2008 First Half Year Results

... the positive top-line results from a Phase III pivotal study evaluating ofatumumab (HuMax-CD20(R)) in two groups of patients with chronic lymphocytic leukaemia (CLL). The study met the primary endpoint in both patient populations and the results from the secondary endpoints also supported the primary endpoint...

Researchers unveil vital key to cancer

...eutical industry. Over 100 kinase inhibitors are currently in clinical trials, and the revolutionary kinase inhibitor Glivec was approved for treating leukaemia in the UK in 2001. Mps1 is particularly important as it controls a 'checkpoint' that cells use to encourage accurate chromosome sorting during mito...

Hey fever! The surprise benefit of allergies

...c diseases are up to 25 percent less likely to get the most common type of Non-Hodgkin Lymphoma (NHL). The InterLymph Symposium is co-hosted by the leukaemia Foundation, the Cancer Institute NSW, UNSW and the National Centre in HIV Epidemiology and Clinical Research. The more atopic diseases the individu...

Heavy birthweight babies twice as likely to develop rheumatoid arthritis

...betes, coronary heart disease, and high blood pressure, for example, have been linked to low birthweight, while an increased risk of breast cancer and leukaemia have been linked to high birthweight. The findings are based on over 87,000 women taking part in the US Nurses' Health Study between 1976 and 2002. ...

Increased cancer risk following the use of radioactive Radium-224 in the therapy

...aematopoietic system: In all, 19 observed cases of leukaemia were documented compared with 6.8 cases that would...ion. In particular, the incidence of acute myeloid leukaemia was significantly increased with 7.0 cases compare...nd no cases in the control group. The frequency of leukaemia was not increased significantly in the control gro...

Organizers of cancer clinical trials are neglecting teenagers and young adults

...vel of 10-14 year-olds entering trials is because they tend to be treated in specialised paediatric units, which, in the UK, run Children's Cancer and leukaemia Group (CCLG) trials. No such co-ordinated body exists for teenagers and young adults aged 17-24 years. They will most likely be treated in an adult wa...

Teenagers and young adults with cancer can face long delays before finally being diagnosed

...d depending on tumour type, with the shortest wait being seen in those with leukaemia (an average of 4.5 weeks) and the longest for bone tumours (an average of 2...welling most commonly in the neck, but it can be elsewhere in the body." leukaemia was the quickest of the cancers to be referred to a specialist, probably be...

Insights into cancer earn Premier's Award Commendation

...rospective new drugs that target Bcl-x could be effective in killing tumour cells. In other notable work, Dr Kelly showed that in several types of leukaemia the frequency of cells sustaining tumour growth is very high. This discovery runs counter to the widely held belief that tumours are sustained only by...

Connecting cancer genes

...d Adams, Experimental Cancer Genetics, from the Wellcome Trust Sanger Institute and are published in Cell. The team used a virus called the murine leukaemia virus to produce mutations in cancer genes: the virus targets white blood cells, resulting in lymphoma, a common tumour of the blood system. "Huma...

New analysis finds daycare attendance early in life cuts childhood leukemia risk by 30 percent

...sk of developing the most common type of childhood leukaemia than those who do not, according to a new analysis..., to be presented Tuesday at the 2nd CHILDREN with leukaemia Causes and Prevention of Childhood leukaemia Conference in London, is the first comprehensive a...

An unexpected way to cause leukemia

... leukaemia cancer of blood or bone marrow is caused by muta...rapies it is crucial to know which mutations cause leukaemia and which cell type gives rise to leukaemic cells....engineering to introduce a mutation found in human leukaemia patients into mice. In the current issue of Cancer...

Leicester scientist announces 'unexpected and exciting advance' in study of cancer type

...ch project at the University of Leicester investigating acute lymphoblastic leukaemia (ALL). Professor Martin Dyer, in the Universitys Department of Cancer St...l Research Fellowship to investigate various aspects of Chronic Lymphocytic leukaemia (CLL) This year Hope Against Cancer (formerly The Hope foundation for C...

Debate over safety of gene therapy trials focuses on issue of informed consent

... a commentary entitled, If It Is Broken Shouldnt it Be Fixed? Informed Consent and Initial Clinical Trials of Gene Therapy. Another, entitled, Case of leukaemia Associated with X-Linked Severe Combined Immunodeficiency Gene Therapy Trial in London, was prepared by the Board of the European Society of Gene and ...

A young star in childhood cancer research

...a for Medical Research. Ms Bachmanns research centred on glucocorticoids, which play a central role in the treatment of childhood acute lymphoblastic leukaemia (ALL). Some tumours develop resistance against the drug and the reasons behind this remain poorly understood. Ms Bachmanns research has led to the id...

BioReliance Appoints Executive Chairman to be Interim CEO and Announces Recent Senior Executive Additions

...Chief Scientific Officer and a member of the Board of BioReliance. He was formerly Chief Medical Officer of Invitrogen and before that Director of the leukaemia Research Fund's Virus Centre and Professor of Veterinary Virology at the University of Glasgow. Dr. Onions was a founding director of Q-One Biotech wh...

T vs. B: Re-engineered human T cells effectively target and kill cancerous B cells

... fight infections can be effective in fighting malignancies associated with B cells (immune cells that create antibodies) such as chronic lymphocytic leukaemia (CLL), ALL, non-Hodgkin's lymphoma (NHL). The researchers have an ongoing study using these T cells in CLL, and have recently begun the planning stag...

New Nano-power Could Make Biopsies Sensitive and Efficient

...tes. In the lab, the researchers showed that a magnetised needle could draw leukaemia cells surrounded by nanoparticles and suspended in blood or other synthetic...with techniques that have recently made it easier to detect tiny amounts of leukaemia cells in biopsies. "I am tempted to think that this technique will...

Chennai Hospital Conducts Bone Marrow Transplantation Successfully

...and a new destination for the cure. It is the first time that an unrelated transplant of stem cells and bone marrow for patients with advanced leukaemia and bone marrow failure has been done in India. A host of reasons contributed to the delay in the procedure being made available in the country. ...

Some Cancers Linked to Very Low Frequency Electromagnetic Fields

...mphoma, and brain tumours. But there was some evidence that higher levels of electromagnetic field exposure had an impact on rates of myeloid leukaemia and Hodgkins lymphoma. Drivers were more than four times as likely to die of myeloid leukaemia, and over three times as likely to die of Hodgk...

Canadian Scientists Create Human Cancer in Mouse

...o human stem cells, John Dick, the lead author of the study and a senior scientist at Princess Margaret Hospital, and his colleagues were able to seed leukaemia - a cancer of the blood in specially bred lab mice. "We haven't proven it, but we believe this process could be used for other cancers too," Dic...

HIV Eradication Unlikely Following Bone Marrow Transplantation

... bone marrow transplant in an HIV-positive individual on HAART. The individual, a young man who required a transplant to treat monocytic acute myeloid leukaemia (AML) had achieved an undetectable viral load for 18 months before the transplant, and remained on HAART – with a short interruption – following the t...

ALL Relapses in Most Children After Treatment

...tected at diagnosis because of their very small numbers, this population of leukaemia cells remained in the patient’s body throughout the disease and continued to thrive even after the major population of sensitive leukaemia cells were destroyed and the patient appeared to have gone into remission. ...

US Student Raising Funds For Cancer-Ridden Indian American

...rican university student in Chicago has launched a leukaemia awareness campaign and fundraiser for the benefit ...p owner, has been diagnosed with acute myelogenous leukaemia (AML). AML is a cancer of the myeloid line o... helps my son with the medicine and the treatment. leukaemia is a very bad kind of cancer from what I have expe...

Gene Therapy for Hereditary Immunodeficiency Diseases

...ficiency and chronic granulomatous disease. There are also initial indicators that point to the efficacy of gene therapy in treating chronic lymphatic leukaemia and haemophilia B. But successes in clinical testing come with their share of setbacks, such as the currently slight margin of therapeutic effectivene...