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Oxidized LDL Cholesterol Linked to Metabolic Syndrome

Condition can lead to heart attack and stroke, researchers note TUESDAY, May 20 (HealthDay News) -- Higher levels of LDL cholesterol "packets" that have undergone oxidation are associated with an increased risk of developing metabolic syndrome, a constellation of conditions that can le...

Abbott's Investigational SIMCOR(R) Offers Comparable LDL Lowering to Simvastatin and Significantly Raises HDL and Lowers Triglycerides in Phase III Study

Six Percent of Patients Discontinued Combination Therapy Due to Flushing ORLANDO, Fla., Nov. 4 /PRNewswire-FirstCall/ -- New data released today showed that Abbott's SIMCOR(R), an investigational, fixed-dose combination of Abbott's proprietary extended-release niacin, Niaspan(R), and simvastat...

Women Less Likely to Control LDL Cholesterol Levels Than Men

A new study has found that women are significantly less likely than men to have their LDL cholesterol controlled to recommended levels . Elevated LDL cholesterol is an important modifiable risk factor for cardiovascular disease, the leading single cause of death for both women and men. ...

Low LDL Levels Lead to Parkinson's Disease

Researchers at University of North Carolina at Chapel Hill suggested that low LDL values can increase the incidence of Parkinson’s disease.// LDL stands for low density lipoprotein; the low values of LDL are associated with good cardiovascular status. Previously associations have been made be...

Plants have ability to significantly lower LDL cholesterol through sterol pills

Washington University School of Medicine in St. Louis have investigated the role of plant sterols in cholesterol lowering ability. They have found that pills containing plant substances called sterols which can help lower cholesterol.// The study samples were patients already on a heart-heal...

Elevated LDL levels in Childhood could be Predictors of Heart Disease

Childhood cholesterol levels may predict a person's risk of developing heart disease in adulthood, according to new research.// A new study finds childhood levels of low-density lipoprotein, or LDL, and body mass index (BMI) predict changes in carotid artery wall thickness in young adults. The c...

Hagens Berman Sobol Shapiro: Vytorin and Zetia Makers Settle Class-Action Suit With Proposed $41.5 Million

...ic drug for about one-third the cost. The Food and Drug Administration (FDA) approved Zetia and Vytorin on the basis that the drugs reduced "bad" - or ldl - cholesterol. Defendants failed to present any evidence to the FDA that these drugs actually reduced the risk of heart disease or strokes. Pl...

FDA Approves LIVALO(R) for Primary Hypercholesterolemia and Combined Dyslipidemia

...er control of and treatment for dyslipidemia. According to the American Heart Association, approximately one out of every three American adults has an ldl cholesterol level of 130mg/dL or higher, which is a major risk factor for coronary heart disease (CHD) and stroke. In addition, less than half of pat...

Consumer Reports Swine Flu Survival Kit Prepares Consumers for Potentially Tough Flu Season This Fall

... (ADHD), heartburn, and insomnia that can save consumers hundreds or even thousands of dollars a year. For example, consumers who need to lower their ldl ("bad") cholesterol by less than 30 percent can save nearly $1,000 a year by taking lovastatin, a generic statin, instead of taking Lipitor, a more ex...

AstraZeneca and the Artery Explorer Take California Residents on Virtual Journey Through the Arteries

...an circulatory system as the arteries become narrow and blocked with plaque. Along the way, they will confront common risk factors for athero, such as ldl (bad) cholesterol, high blood pressure, and smoking. The experience concludes with a head-on collision with a blood clot, demonstrating how athero can...

Giving Statins to Kids Provokes Debate

...ile also promoting the ability to clear "bad" (LDL) cholesterol from the bloodstream. "The consensus is that, for children with very high levels of ldl cholesterol at age 8 or older, physicians should consider statins if lifestyle and diet intervention have not been successful," said Dr. Stephen R. Da...

Abbott Reports Strong Second Quarter Results; Confirms Double-Digit Earnings Growth Outlook for 2009

...bination of TRILIPIX and rosuvastatin helped up to three times more patients simultaneously reach all three key lipid targets - HDL, triglycerides and ldl - than the pre-determined monotherapy. These results were presented at the American Diabetes Association's 2009 Scientific Sessions. Extended L...

Blood vessel bends and branches put the brakes on statins

...e action of a commonly-used drug, and could point the way towards new targets to improve artery health throughout the body. Statins lower harmful ldl cholesterol - in 2008 nearly 50 million statin prescriptions were written for people at high risk of heart attack in England², where they are es...

Pluronic L-81 is a potential anti-diabetic drug?

...ylene oxide. It has been reported that a nonionic L-81, effectively inhibits absorption of dietary lipids from the intestine and secretion of VLDL and ldl from the liver. Although L-81 is a potent anti-obesity drug, its potential in alleviating obesity-induced insulin resistance and type 2 diabetes has n...

For Treatment of Dyslipidemia, Surveyed Physicians are Increasingly Switching Patients to a More Potent Statin Following the ENHANCE and SEAS Trials

...es, finds that, in the treatment of dyslipidemia patients who fail to reach ldl goal, surveyed physicians are increasingly switching patients to a more pot...y directors know that ENHANCE showed Vytorin was more effective at reducing ldl cholesterol than simvastatin. The negative press surrounding the results of...

VAP(R) Cholesterol Test Highlighted in Groundbreaking Book on Longevity

...and triglycerides are measured, while the ldl is calculated from the other results. In the VAP test, ldl is measured directly, providing much more...e. those with triglycerides > 150, HDL < 40, ldl >130, total cholesterol > 200) should also o...

Study Supports Wider Use of Statins

...Health has announced that it will review the guidelines for prescribing statins, Gotto said. Those guidelines now focus on reducing elevated levels of ldl cholesterol, the "bad" kind that clogs arteries. The increased benefit of statins is believed to be due to their anti-inflammatory activity, Gotto...

Nuvilex Cites Study that Suggests Red Yeast Rice, an Active Ingredient in Cinnechol, Can Help to Improve Cardiovascular Health

... to decrease levels of low-density lipoprotein, or ldl cholesterol, in dyslipidemic patients. ldl cholesterol is known more informally as "bad" chol...rcise regimen that included red yeast rice reduced ldl cholesterol by an average of 27.3%, compared to 5....

China Pharma Holdings, Inc. Announces SFDA Approval for Rosuvastatin Clinical Trials

...eric version of Crestor(R), which is deemed one of the most potent cholesterol-lowering medicines available and has been shown to significantly reduce ldl cholesterol (so-called "bad cholesterol"). The use of Crestor(R) has translated into a 60% decrease in the number of cardiac events (heart attack, sud...

Exercise improves functional and psycological ability and reduces steroid need in rheumatoid arthritis

...ients reported stopping concurrent NSAID (non-steroidal anti-inflammatory drug) treatment altogether following the exercise programme (p=0.083) Mean ldl (low-density lipoprotein) cholesterol increased from 90mg/dl to 125mg/dl (p=0.018) 40% improvement in the Depression Anxiety Stress Scales (DASS), a...

New Study Shows Coaching to Patient Activation Levels Improves Disease Management Outcomes

...ith an increase of 20% in the control group. The PAM group also experienced statistically significant improvements in diastolic blood pressure and in ldl cholesterol levels relative to the control group, and increased their adherence to recommended immunization and drug regimens, including the influenza...

New Study Shows Coaching to Patient Activation Levels Improves Disease Management Outcomes

...ith an increase of 20% in the control group. The PAM group also experienced statistically significant improvements in diastolic blood pressure and in ldl cholesterol levels relative to the control group, and increased their adherence to recommended immunization and drug regimens, including the influenza...

Another Blood Fat Fuels Heart Attack Risk

...on [heart attack], similar to that for the highest ldl cholesterol levels," said Dr. Borge G. Nordestgaar...ordestgaard said. LPA consists of a molecule of ldl cholesterol, the "bad" kind that clogs arteries, a...otein. The number of protein units attached to the ldl unit can vary widely. Nordestgaard and his coll...

'Eco-Atkins' Diet Sheds More Than Pounds

...rticipants in both groups lost the same amount of weight -- 8.8 pounds. The real triumph, however, was seen in the 0.6 percent greater reduction in ldl ("bad") cholesterol levels in the group eating more plant-based proteins. Improvements in total cholesterol, ratios of proteins that adhere to fats, a...

LSUHSC researchers first to document early signs for diabetes in kids as young as 7

...earchers found that the child's current fat weight is the strongest predictor for poor insulin sensitivity which is a risk factor for type 2 diabetes. ldl (bad cholesterol) was also strongly associated with insulin sensitivity in the prediction model. Previously unidentified Metabolic Syndrome markers di...

Abbott's TRILIPIX(R) (Fenofibric Acid) in Combination With Rosuvastatin Calcium Helps Patients With Mixed Dyslipidemia and Type 2 Diabetes Meet American Diabetes Association Lipid Targets

... reach combined targets for HDL, triglycerides and ldl than the pre-determined therapy alone NEW ORL...l three key lipid targets - HDL, triglycerides and ldl - than the pre-determined monotherapy. Results fr...ne used along with diet to lower triglycerides and ldl (bad) cholesterol, and increase HDL (good) cholest...

Abbott and AstraZeneca Extend Relationship to Include Co-Promotion of TRILIPIX(R) (fenofibric acid)

...escription medicine that is used along with diet to lower triglycerides and ldl (bad) cholesterol, and increase HDL (good) cholesterol. TRILIPIX is also u...igh risk of heart disease and are taking a statin medicine to control their ldl cholesterol. TRILIPIX has not been shown to prevent heart attacks or strok...

Abbott and AstraZeneca Submit New Drug Application to the FDA for CERTRIAD(TM), an Investigational Treatment for Mixed Dyslipidemia

...aggressive management of lipids, including a lower ldl goal for many patients, as well as more aggressive...ared to rosuvastatin monotherapy and the effect on ldl compared to fenofibric acid monotherapy in patient...lesterol diet in adults to lower triglycerides and ldl (bad) cholesterol, and increase HDL (good) cholest...

AstraZeneca, the National Alliance for Hispanic Health and LULAC Join Forces to Promote Needed Heart Health Education in Hispanic Communities

...culatory system as the arteries become narrow and blocked with plaque. Along the way, people are confronted by common risk factors for athero, such as ldl (bad) cholesterol, high blood pressure, and smoking. The experience, which is narrated and illustrated in Spanish, culminates with a head-on collision...

New Survey Shows Consumers Making Effort to Buy Healthy Foods But Buyer Beware: 'Zero' Isn't Always Zero

...ey. Even seemingly insignificant amounts of trans fat can have a significant impact on health. The AHA reports trans fat has been shown to raise ldl ("bad") cholesterol and lower HDL ("good") cholesterol, increasing the risk of coronary disease or stroke; and it has been associated with a higher ri...

Two Studies at AACE 2009 Annual Meeting Highlight Effects of Welchol(R) (colesevelam HCl) on Blood Glucose and LDL-C in Patients with Type 2 Diabetes

...icantly improved glycemic control and reduced mean ldl cholesterol (LDL-C) when added to metformin monoth...ent of patients with type 2 diabetes have elevated ldl cholesterol and are not at the recommended goal of... type 2 diabetes by significantly lowering A1C and ldl or 'bad' cholesterol, thereby offering physicians ...

DASH Diet Has Extra Benefits for Women's Health

...m Hg, a decrease that could lower the rate of heart failure an estimated 12 percent, Levitan noted in a news release from the journal. Lower levels of ldl cholesterol, the estrogen-like effects of some of the nutrients in the diet, and a decrease in oxygen-related cell damage may also contribute to reduc...

More evidence for the benefit of exercise in cardiovascular disease -- and even in heart failure

...tationary handgrip test heart rate, blood pressure and stroke volume were all improved in the exercise group, as were some metabolic markers such as ldl cholesterol. 2. In comparison to PCI in patients with stable coronary disease Percutaneous coronary intervention (PCI) with balloon angioplasty ...

Cholesterol Drugs May Help in Cardiac Emergency

...of those in the statin group versus 20.5 percent of those not taking the drug. There was also an expected 29.5 percent reduction in blood levels of ldl ("bad") cholesterol among those who took the statin, the Czech physicians noted. But the benefit seen in the study most likely was not due to the c...

Managing Blood Pressure, Cholesterol Cuts Stroke Risk

...at over an average of 4.9 years, patients who maintained optimal levels of ldl ("bad") cholesterol, HDL ("good") cholesterol, triglycerides and blood pres...ology's annual meeting in Seattle. "In this study, we show that lowering ldl cholesterol is important to reduce the burden of new stroke and myocardial ...

Controlling Cholesterol, Blood Pressure Adds Up to Prevent Stroke

... American Academy of Neurology's 61st Annual Meeting in Seattle, April 25 - May 2, 2009. Researchers looked at four risk factors for stroke: high ldl cholesterol, low HDL cholesterol, high triglycerides, and high blood pressure. They found that for each risk factor that is controlled at the optimal ...

Many Who Should Use Statins Don't

...777 adults who met the criteria set by the National Cholesterol Education Program for statin therapy. Those criteria consider not only blood levels of ldl cholesterol, the "bad" kind found in artery-clogging plaques (in general, a reading below 100 milligrams per deciliter is recommended), but also other...

PDAs, more education help doctors follow cholesterol treatment guidelines

...y under certain conditions. The complexity of the guideline made it the perfect subject for study, Bertoni said. "The guideline doesn't say if your ldl cholesterol is a specific level, you should treat," he said. "It says you should consider all risk factors before deciding to prescribe a lipid-loweri...

New Study Shows Fish Oil Improves Cholesterol Levels in Professional Football Players

...3 fatty acids per soft gel). "The results illustrated a rather dramatic decrease in triglyceride levels, a healthy increase in HDL, and lowered ldl in the athletes who used a moderately high dose of omega-3 EFA fish oil," relates Joseph Maroon, MD, a board certified neurosurgeon who serves on the ...

The Traveling Nut: Researchers From Around the World Explore the Impact of Almonds on the Body

... Researchers measured body fat, total cholesterol, ldl cholesterol, oxidative stress, blood sugar, insuli...se in body fat by 1%, total cholesterol by 8%, and ldl cholesterol by 13%. Most importantly, researchers ... the blood increased, as well as the resistance of ldl cholesterol against oxidation, when tissues were t...
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