Insuli

Link between birth weight and Insulin Resistance

According to researchers in England, a baby's birth weight is connected to the mother's insulin resistance in late adulthood. The study also shows women with the lightest and heaviest offspring had the highest risk of developing diabetes.// More than 4,100 women ages between 62 and 75 years participated in the study. Researchers found, as birth weight increased every 2.2 lbs, women had...

Animal insulin product to be discontinued by drug major Eli Lilly

The Chairman and Managing Director of Eli Lilly and Co., India, disclosed on January 3rd, during the announcement of a price cut in the company's human insulin product 'Huminsulin', that its animal insulin product 'Iletin' will be phased out from the market by the end of this year. He added that the company// resorted to this move due to the growing use of human insulin products and the p...

Easier Methods Required to Screen Insulin Resistance

Insulin resistance is a major medical problem often leading to diabetes and cardiovascular disease. Being overweight greatly increases the odds someone will be insulin //resistant, but not all overweight or obese people are afflicted. The insulin suppression test used to identify insulin resistance, however, it is too difficult to administer to large numbers of people. Researchers have...

Easier Methods Required to Screen Insulin Resistance

Insulin resistance is a major medical problem often leading to diabetes and cardiovascular disease. Being overweight greatly increases the odds someone will be insulin // resistant, but not all overweight or obese people are afflicted. The insulin suppression test used to identify insulin resistance, however, it is too difficult to administer to large numbers of people. Researchers hav...

Insulin Resistance Linked To Difference In Gender

Type 2 diabetes used to be considered an adult disease, but now more children are being diagnosed with type 2 diabetes.// Research has shown girls are affected more than boys. Now, a new study shows sex-linked genes may explain this difference between girls and boys being diagnosed with type 2 diabetes. Researchers in the United Kingdom are conducting a study which aims to establish whi...

Adopting Easier Methods To Screen Insulin Resistance

Insulin resistance is a major medical problem often leading to diabetes and cardiovascular disease. Being overweight greatly increases the odds // someone will be insulin resistant, but not all overweight or obese people are afflicted. The insulin suppression test used to identify insulin resistance, however, it is too difficult to administer to large numbers of people. Researchers have...

Another Alternative For Diabetics On Insulin

New research shows inhaled insulin is effective and well tolerated in patients with type 1 diabetes. // The treatment also provides glycemic control comparable to a conventional insulin regimen. For the study, 335 participants randomly received either inhaled insulin with bedtime Ultralente or two to three injections of regular insulin for six months. Hypoglycemia, or the abnormal decrea...

Understanding Insulin Resistance

Based on findings of a recent study researchers say girls are affected more than boys. Researchers say sex-linked // genes may explain this difference between girls and boys being diagnosed with type 2 diabetes. Researchers are in the process of conducting a study which aims to establish which children are insulin-resistant and why. The study included 307 healthy children 4 or 5 years ol...

Caffeine Intake May reduce Insulin Sensitivity

In a study published in Diabetes Care, March 2005, scientists have reported that caffeine may cause insulin// sensitivity in people. Insulin sensitivity is the measure for the risk of heart disease. If a person is more insulin sensitive then he has a lower risk of heart problems. Diabetes type 2 happens when body cannot use its own insulin to control blood sugar. As this ha...

Brain stem cells to help in producing insulin

Researchers from Stanford University had found out that it is possible to generate insulin from brain stem cells// Since the time the first does of insulin was given to patient suffering from type 1 diabetes mellitus, the demand for insulin had often overcame its supply. Moreover, where there is availability of insulin, even there remains a lack in control of diabetes in patients. On...

Junk Food Causes High Level Of Insulin Resistance In Children

Research involving 3,189 school children from Denmark, Estonia and Portugal// reported that children from poor families don’t necessarily have worse health compared to children from children’s of rich and better-educated parents. The results of the study were published in British Medical Journal. The results of the study challenge the results of the earlier reported results that adverse s...

Increasing Insulin Response In Type 2 Diabetics With New Protein Mixture

Diabetes remains one of the significant health problems to be tackled despite significant medical// advancement. It requires a multi faceted approach. A protein-based diet could help in improving resistance in Type II diabetes. A recent study shows that consuming a protein hydrolysate and amino acid mixture with carbohydrates increases insulin production in type 2 diabetics, and could...

Now insulin can be inhaled

In a breakthrough that would alter the lives of millions, scientists at the University of Scarthclyde and Glasgow have developed and patented a simple method of administering protein based drugs such as insulin using inhalers. The manufacture of tiny protein coated micro crystals can pass through the lung wall and into the blood stream using dry powder inhalers similar to those...

Elevated Insulin Levels To Influence Levels Of Inflammatory Markers

Increase in the levels of insulin can raise the level of inflammatory makers that influence the Alzheimer’s’ Disease. The study is being published by Archives of Neurology. Conditions of insulin resistance and hyper-insulinemia are associated with elevated levels //of inflammatory markers and increase the risk for Alzheimer disease (AD). Inflammation has been proposed as a key pathogen...

Alzheimer's Disease Caused By Insulin Increase

Mark A. Fishel, M.D., from the University of Washington, Seattle, and colleagues, have investigated the role of insulin increase in Alzheimer’s disease. Moderately elevated levels of insulin increase the levels of inflammatory markers and beta-amyloid // in plasma and in cerebrospinal fluid and these markers may contribute to Alzheimer's disease The test was conducted in 16 healthy ol...

New Drug Exubera (Oral Inhaled Insulin) To Be Monitored By Pfizer

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Exubera could mean the end of an insulin injection era for diabetics

Diabetes and cancer remain the most feared diseases all around the world. Researchers have now come up with an insulin inhaler, potentially offering adult diabetics an alternative to injections// for controlling their blood sugar. The drug is yet to be approved by the FDA. If approved, the drug, known as Exubera, would mean an end to the insulin injections taken by millions worldwide. Th...

Use of a fast-acting insulin analog to control diabetic ketoacidosis in Children

Diabetic ketoacidosis (DKA) is a life-threatening condition that frequently requires hospitalization in children with type 1 diabetes.// The critical factors in the treatment of DKA include careful and frequent monitoring of the patient, skillful fluid and electrolyte adjustment, and the initiation of insulin therapy after the initial restoration of fluid volume has been achieved. Continu...

HIIP- A Novel Inhaled Insulin Delivery System As An Alternative To Injectable Insulin Therapy

The disease burden of diabetes continues to grow and currently affects more that 18 million Americans and their families. These data emphasize a need for alternative diabetes therapies with earlier more physiologic use of insulin.// The delivery of insulin by the lung may provide an attractive alternative for many patients with diabetes. However, alternative insulin delivery systems mus...

Tea Found To Boost Insulin Production And Prevent Cataract

Diabetes is a multifactorial disorder that can lead to a multitude of complications if left untreated. A new research conducted on animal models suggests the possibility of using tea as a form of treatment for the chronic disorder. More specifically, //it has been found to prevent the incidence of cataracts, a significant health problem faced by majority of the diabetics worldwide. Re...

Nurse Held Responsible For Insulin Overdose

A massive overdose of insulin led to the death of 62-year-old Moira Pullar on 17 January 2004 at Monklands General Hospital. The wrong dose was administered by a nurse who failed to cross check// the records in the hospital, or consult a doctor. The overdose of insulin resulted in bronchial pneumonia after cardiac arrest and brain damage. The poor handwriting of one nurse was misread by...

Inhaled Insulin To Be Made Available in India

The world's largest drug maker, Pfizer has announced that it intends to fast track its inhaled insulin Exubera in India. Exubera received regulatory approvals from the US Food and Drug Administration // and the European Commission last week. The drug has been developed in collaboration with Sanofi-Aventis and Nektar Therapeutics. It is a relatively harmless form of insulin in that no n...

Inhaled Insulin Could Rock The Drug Market Soon

Following approval of Exubera, an oral insulin formulation by the U.S. Food and Drug Administration and the European Commission, the sales of the new treatment // modality is expected to soar in the next couple of months. The drug is a combined effort of three major pharmaceutical companies Sanofi-Aventis, Pfizer and Nektar Therapeutics. The new formulation could eventually save the tro...

Islet cells producing insulin cultivated in the lab

Now there is an answer, not to far, to the complexities of Type I diabetics and insulin injections.This is according to researchers at the University of Calgary whose bioengineering team announced //that they have developed a way of growing pancreatic cells in their laboratory. In the words of Dr. Leo Behie, “This is a significant milestone on the path to effectively producing huma...

Oral Human Insulin to Soon Go on Trial

Biocon's 'oral human insulin' is to soon go on Phase I trial. It maybe as early as a month – declared the MD of Biocon, Ms.Kiran Mazumdar Shaw. Ms.Shaw was speaking at the conference organized in Chennai by Madras Diabetes Research Foundation(MDRF) on awards for innovation and R&D.// There are close to 34 million diabetics in India and any research related to diabetes should always b...

Medtronic’s Insulin Pump Receives Regulatory Approva

The U.S. Food and Drug Administration has approved Medtronic's MiniMed Paradigm insulin pump, which is also a glucose monitor. This is the first device to deliver // insulin as well as monitor glucose levels in the blood. The MiniMed takes blood glucose every five minutes and gives 288 readings per day. It consists of two components, one of which is an electrode inserted under the skin....

Boca Recalls Insulin Syringe Product Due To Contamination

Boca Medical Products, Inc., based in Coral Springs, Florida, have decided to recall around 4000 boxes of Ultilet Insulin Syringe 30g 1/2cc due to possible // contamination of Bacillus Cereus and Staphylococcus Intermedius. The products if not recalled, may degrade the insulin thereby leading to problems such as maintaining the insulin levels. The concern is on the process of evaluating t...

High Cost Forces NHS To Reject Inhaled Insulin

Exubera, a new form of insulin that could revolutionize diabetic treatment has been rejected by the NHS on account of high cost. // The drug can be inhaled and provides an ideal alternative to the daily insulin injections taken by numerous diabetics, worldwide. Patients with both Type 1 and Type 2 diabetes can use the new form of insulin. The annual cost associated with this form of i...

A New study Throws Light On The Growth & Functions Of Insulin Producing Beta Cells

The latest study that was lead by Joslin Diabetes Centre throws much needed light on how insulin-producing beta cells grow and function. These findings// they hope will help in new treatments for people with diabetes. The Joslin Diabetes Centre in Boston, have conducted a study that now proves conclusively that two receptors in the insulin-producing beta cell do not affect in the deve...

Insulin Crystals Holds Promise In Diabetes research

A novel method to aid the formation of insulin crystals in the pancreas is a major discovery effected by a University of Houston professor and his student, which holds promise in the field of diabetes research and diagnosis. // Peter Vekilov, associate professor of chemical engineering, and Dimitra Georgiou, a recent doctoral graduate in chemical engineering, both in UH's Cullen College...

Insulin and Growth Hormone, Expands Life Span?

Life-span facts have always been shrouded in ambiguity, though studies have hinted at the connection between reduction in calories and longevity. // Now, a novel report has suggested that growth hormone, as well as insulin has a bearing on the influences of calorie restriction and does contribute to extending life. Dr. Andrezej Bartke from Southern Illinois University in Springfield...

Pfizer vouches safety of long-term inhaled insulin.

Los Angeles: Pfizer has indicated that recent clinical trials of inhaled insulin has received the approval from the drug regulators and is found to be useful in regulating blood sugar levels spanning a 2 year period. // This product, named Exubera, is slated to be introduced into the United States market soon after the U.S. Food and Drug Administration approves it for use in adults wit...

Inhaled Insulin: A New Modality for Management of Diabetes

It is widely known that diabetes, one of the world’s leading debilitating diseases, has reached overwhelming proportions // . It affects an estimated 194 million adults worldwide. Therefore, there is a huge demand for innovative and effective therapeutic options that are beneficial to the patients. There are two types of diabetes: Type-1: Also known as Juvenile Diabetes, i...

A Carrier Protein Associates With Human Insulin Resistance

A study reports that low blood protein levels are found to be associated with reduced insulin resistance and thus risk of diabetes// , metabolic syndrome and cardiovascular disease decreased. A protein in blood called retinol-binding protein 4 (RBP4), when reduced by the effect of modified diet and good exercise programs proved to drop the risk factors of diabetes – finding reports. <...

NICE Setback Rules for Pfizer's Inhaled Insulin

Diabetics with needle phobia and patients with severe problems in injection sites get benefited from Pfizer’s Exubera, an inhaled insulin product (short-acting, powder form of insulin) //– said The National Institute for Health and Clinical Excellence (NICE), Britain's watchdog. A suggestion has already said by the National Institute for Health and Clinical Excellence (NICE) that inhale...

Menin Gene Mutation made Insulin Secreting Cells to Proliferate

Acute loss of a protein named menin – involved in tumor-suppression or cell-proliferation-suppressing function resulted in the proliferation of pancreatic islet cells, which again affected blood sugar// regulation - researchers at the University of Pennsylvania School of Medicine reports. In humans menin gene (Men1) mutation can lead to a genetic disease called Multiple Endocrine Neopla...

Bayer to Market Biocon Insulin in China

Indian biotech major Biocon Ltd has roped in Bayer HealthCare to market its recombinant human insulin Insugen in the Chinese market, the company //said in a statement Wednesday. The Bangalore-based biotech firm plans to launch Insugen in China by 2007-08 after completing the registration trials and seeking the regulatory approvals. "The marketing tie-up with Bayer will be...

European Commission Clears Diabetic Insulin for Pregnant Women

Healthcare major Novo Nordisk Friday said the European Commission (EC) had approved its rapid-acting insulin NovoRapid for use by pregnant women with diabetes.// According to a company statement here, the EC approval follows results of the random trials of modern insulin in pregnant women with type 1 diabetes. "NovoRapid is the first modern insulin that can be used in preg...

Insulin Resistance: An Important Indicator of Heart Disease and Diabetes for Teens

Researchers have pointed out that Insulin resistance during adolescence is an important indicator of diabetes and heart disease in adulthood.// Obesity is indicated by a body-mass index of 30 or higher. The key factor to ward off diabetes and heart disease is to ensure that people do not gain weight in childhood and adolescence, which will certainly reduce the risks of disease during...

A New Gene to Contribute in Insulin Metabolism

Chemists and biologists from the new interdisciplinary LIMES (Life and Medical Scientists) Center at University of Bonn have found a new gene //which might, if defect, contribute to the development of Type II diabetes. Flies in which this hereditary factor is defective are also significantly smaller than other members of their species and live appreciably longer. The gene seems to have...