Johnson & Johnson and Elan Corporation plc Announce Definitive Agreement for Alzheimer's Immunotherapy Program and Equity Investment

NEW BRUNSWICK, N.J. and DUBLIN, July 2 /PRNewswire-FirstCall/ -- Johnson & Johnson (NYSE: JNJ ) and Elan Corporation plc (NYSE: ELN ) today announced a definitive agreement whereby Johnson & Johnson will acquire substantially all of the assets and rights of Elan related to its Alzheime...

Sublingual immunotherapy for inhalant allergies deserves deeper consideration

Alexandria, VA Sublingual immunotherapy for the treatment of allergy symptoms caused by a wide variety of environmental inhalants has been effectively used in Europe. It should be employed to further treatment of allergies in the United States, where allergic symptoms are largely undertreated, ac...

Prostate cancer immunotherapy significantly prolongs survival in men with advanced prostate cancer

CHICAGO, ILSipuleucel-T (Provenge), an experimental immunotherapy improved survival in men with metastatic disease, according to new results to be presented April 28 at the American Urological Association (AUA) Annual Scientific Meeting in Chicago. These data from the Phase 3 Immunotherapy for Pro...

A new light on tumor immunotherapy for gastric cancer

Dendritic cells (DCs) are professional antigen presenting cells (APCs) that both initiate and modulate the immune response. DCs are cells in the pathway of antigen capture and presentation to T cells, with the unique ability to directly prime nave CD4+ and CD8+ T cells. Gastric cancer is one of th...

33rd Annual Hutch Holiday Gala Raises Millions for Cancer Immunotherapy Research

SEATTLE, Dec. 8 /PRNewswire/ -- Saturday's Hutch Holiday Gala raised more than $2.2 million for cancer and related disease research at Fred Hutchinson Cancer Research Center. "Help the Hutch," a portion of the live auction during which guests raise their bid cards for specific contribution...

MaxCyte to Present Targeted Cancer Immunotherapy Product at 50th Annual Meeting of the American Society of Hematology

'A Highly Efficient, Clinical Method to Redirect the Specificity of Immune Cells and Enhance Their Anti-Tumor Capacity' GAITHERSBURG, Md., Dec. 4 /PRNewswire/ -- MaxCyte, Inc., a clinical-stage therapeutics company and pioneer in clinical scale, non-viral cell loading systems, announces ...

OHSU Cancer Institute researcher: radiation, immunotherapy gives greater effectiveness

PORTLAND, Ore. Oregon Health & Science University Cancer Institute researchers have found the right formula of radiation and immunotherapy for fighting lung cancer tumors in mice, which they hope will translate to better treatment in human lung cancers. The study was presented today at the 50...

Latest research on allergies: Specific immunotherapy can help

The German Institute for Quality and Efficiency in Health Care has assessed recent evidence on allergies. It found that the once controversial immune therapy against allergy symptoms can definitely help many people with allergies. When it is green and the flowers have returned, the allergy seas...

Dangerous Side Effect Found in Cancer Immunotherapy Research

Lab experiment resulted in T-cells spreading beyond treatment area TUESDAY, June 3 (HealthDay News) -- When scientists first began looking into using the body's own immune system to target malignancies, it was hoped that the therapy would be able to zero in on a specific cancer withou...

Oral Allergy Immunotherapy Helps Control Asthma

Drops or tablets avoid the pain and side effects of shots, review finds TUESDAY, March 4 (HealthDay News) -- Oral allergy immunotherapy -- in the form of drops or tablets -- is effective at reducing asthma symptoms and the need for asthma medications in children who have what's known a...

A Few Shots Away: Immunotherapy May Relieve Allergy Symptoms

MILWAUKEE, Jan. 9 /PRNewswire/ -- Those who suffer from allergic asthma, rhinitis, conjunctivitis or stinging insect allergies may be good candidates to receive immunotherapy, also known as "allergy shots," according to the American Academy of Allergy, Asthma & Immunology (AAAAI). "Immunothe...

Device aims to decrease wait period for patients needing immunotherapy

HOUSTON - Researchers from the Children's Cancer Hospital at The University of Texas M. D. Anderson Cancer Center have created a device that significantly decreases the time needed to produce genetically manipulated T cells in preclinical tests for leukemia. Paul (Yoonsu) Choi, Ph.D., presente...

Towards improved immunotherapy

Amsterdam, December 1, 2008 A study (doi:10.1016/j.clim.2008.07.027) published by Elsevier this month in Clinical Immunology , the official journal of the Clinical Immunology Society (CIS), describes a new method that facilitates the induction of a specific type of immune suppressive cells, call...

Educational Symposium to Present Panel Discussion on Melanoma Treatments and Immunotherapy

CONCORD, Mass., Nov. 3 /PRNewswire-USNewswire/ -- The Melanoma Foundation of New England invites melanoma patients, survivors, families, and friends to its fall symposium: "Updates in Melanoma Treatment" presented by F. Stephen Hodi, MD, Director of the Melanoma Program at Dana Farber Cancer I...

FDA Says, 'Wait' To Dying Men; Coast-To-Coast Prostate Cancer Demonstrations on May 30th in Protest of FDA Failure to Approve Safe, Effective Immunotherapy

DUBLIN, Ohio, May 12 /PRNewswire/ -- On May 30, 2008, CareToLive will take to the streets with coast-to-coast protests in Chicago, New York, Philadelphia, Cleveland, Madison, Atlanta, Seattle, Dearborn, and Tampa. Joining us will be the Cancer Cure Coalition, the Abigail Alliance, A Right To L...

Cell Genesys Reports Additional Data From Phase 2 Clinical Trial of GVAX Immunotherapy for Pancreatic Cancer

Cell Genesys, Inc. (Nasdaq: CEGE) today announced follow-up data from a Phase 2 clinical trial of GVAX immunotherapy for pancreatic cancer which was conducted by the Johns Hopkins Sidney Kimmel Cancer Center. The trial enrolled 60 patients with operable pancreatic cancer who received GVAX after su...

Passive Immunotherapy Could Prevent Avian Flu from Affecting Humans

According to a pilot study conducted by Jiahai Lu, Ph.D., of the school of public health at Sun Yat-sen University said that passive immunotherapy// is the best way to treat highly pathogenic avian influenza in humans. Passive immunotherapy uses antibodies from horses. Purified antibodies to t...

Ferring Pharmaceuticals Announces Trade Name FIRMAGON(R) (degarelix for injection) for Advanced Prostate Cancer Treatment

...ts from a 1-yr, multicentre, randomised phase 2 dosage-finding study in the treatment of prostate cancer. Eur Urol. 2008;54(4):805-813. (4) Doehn C. immunotherapy of Prostate Cancer. Eur Urol. (2006);53-4:681-683. ...

TGen-led team is 1 of 7 selected for $1 million skin-cancer grants

...arcus Bosenberg, M.D., Ph.D., Yale University Michael Krauthammer, M.D., Ph.D., Yale University David Stern, Ph.D., Yale University Combinatorial immunotherapy for Melanoma with B7-H1/PD-1 Checkpoint Blockade Principal Investigators: Team Lead: Drew Pardoll, M.D., Ph.D., Johns Hopkins University Lieping ...

US HIFU Secures $5 Million Financing From MMV Financial

...financing commitment from Toronto-based MMV Financial ("MMV"). US HIFU continues to pioneer on-going cutting-edge clinical research, including immunotherapy and focal therapy, for the treatment of prostate cancer. The company looks forward to expanding plans for clinical trials that will give patients the ...

A Phase III Alzheimer's Drug Increases Levels of Beta Amyloid in the Brain - But Still Provides Benefits

...f dimebolin could be amyloid-lowering. immunotherapy Against Tau Tangles in Alzheimer's Mouse Models immunotherapy (treatment by inducing, enhancing, or suppressing ...eimer's disease. Earlier, late stage, anti-amyloid immunotherapy trials in people were complicated, and eventually ...

New Report Just Published: World Multiple Myeloma Therapeutics Market Report

...y II-33 Radiation Therapy II-33 Stem Cell Transplants II-33 Biological Therapy II-34 Targeted Therapy II-34 Gene Therapy II-34 immunotherapy II-34 Monoclonal Antibody Treatment II-35 Vaccines II-35 Donor Lymphocyte Infusion II-35 Hematological Cancer Drug Classes II-35 H...

Kids May 'Learn' to Tolerate Food Allergens

...y to food allergies, through processes called oral immunotherapy and sublingual immunotherapy. They believe they...d used in treatment," Sicherer said. Sublingual immunotherapy works by placing an extract of the food allergen u...em without prompting an allergic reaction. Oral immunotherapy takes it a step further by having children eat tin...

CEL-SCI Completes $5.85 Million Registered Direct Offering

... VIENNA, Va., June 30 /PRNewswire-FirstCall/ -- CEL-SCI Corporation (NYSE Amex: CVM ), a late stage cancer immunotherapy company, today announced that it has completed a registered direct offering under which it raised gross proceeds of $5.85 million before deducting pla...

Entest BioMedical Inc. Adds Former National Cancer Institute Researcher to Scientific Advisory Board With Focus on Stem Cell Cancer Patient Therapies

... population of immune cells from a patient's own stem cells to reactivate the patient's immune system. This strategy represents a novel and effective immunotherapy especially for cancer patients and HIV patients who have injured immune systems and are at high risk of infection with bacteria and viruses." Ab...

Researchers work to boost effectiveness of the flu vaccine

...say. That doesn't mean vaccines are bad, it just may help explain why they aren't as good as they could be, says Dr. Andrew Mellor, director of the immunotherapy Center at the Medical College of Georgia and Georgia Research Alliance Eminent Scholar in Molecular Immunogenetics. His team along with viral immun...

Ortho Biotech Oncology Research & Development Announces Collaboration with National Cancer Institute to Develop Novel Cell Therapies to Treat Cancer

...reatments for a variety of cancers. These adoptive immunotherapy technologies are designed to work by helping the i...enberg has been a pioneer in the field of adoptive immunotherapy of cancer for decades. His group developed Tumor ... optimize technologies and to begin testing of our immunotherapy technology in melanoma patients by the end of 2009...

Vaccine shows therapeutic promise against advanced melanoma

...one of the most lethal cancers, advanced melanoma, has shown improved response rates and progression-free survival for patients when combined with the immunotherapy drug, Interleukin-2, according to researchers from The University of Texas M. D. Anderson Cancer Center. The findings, presented today at the Amer...

Experts Optimistic About Melanoma Vaccine

...the American Cancer Society. The study, a phase 3 clinical trial involving 185 people, found that using the peptide vaccine in combination with the immunotherapy drug Interleukin-2 improved response rates and progression-free survival, according to University of Texas M.D. Anderson Cancer Center researchers, wh...

New therapy enlists immune system to boost cure rate in a childhood cancer

...findings online on May 14. Maris explained that immunotherapy for cancer involves triggering the body's immune s...ll transplantation). The patients who received the immunotherapy were 20 percent more likely than those in the stan... the benefits of immunotherapy. "This experimental immunotherapy is poised to become part of the new standard of ca...

DFG establishes nine new collaborative research centers

...assembled Transregional Collaborative Research Centre 60, "Mutual Interaction of Viruses with Cells of the Immune System: From Fundamental Research to immunotherapy and Vaccination". Working together, German and Chinese researchers will study the interaction of persistent viruses and the body's own cells in both c...

Arthritis drug might prove effective in fighting the flu, study suggests

...ending on the results, Dr. Farber hopes to one day bring this promising new immunotherapy to the clinic for the benefit of patients. E. Albert Reece, M.D., Ph.D.,...ken within 48 hours of the first symptoms. Dr. Farber points out that an immunotherapy with a drug such as Abatacept would be effective against different strains ...

Bioniche Phase III Clinical Trial with Urocidin(TM) Progressing Well

...egistration trial evaluating Urocidin in the treatment of non-muscle-invasive bladder cancer that is refractory (unresponsive) to the current standard immunotherapy - Bacillus Calmette-Guerin (BCG). The Data Safety Monitoring Committee (DSMC) held its eighth meeting regarding this clinical trial earlier this wee...

InDex Pharmaceuticals AB Engages PharmaVentures to Facilitate the Licensing of Kappaproct(R) After Phase IIa Trial Achieves Clinical Endpoints Early

... 187 fiona.bishop@pharmaventures.com InDex Pharmaceuticals AB ("InDex") is a clinical stage biopharmaceutical company building a leading immunotherapy franchise based on its DIMS platform (DNA-based immunomodulatory sequence). DIMS drugs are developed to treat diseases within a variety of therapeutic...

Light Sciences Oncology Announces Results of Study on Immunotherapeutic Mechanism of Aptocine(TM), a Novel Light-Activated Drug Therapy for Cancer

...onducted by Dr. Sandra Gollnick at the Roswell Park Cancer Institute in Buffalo, New York. "With mounting evidence that Aptocine may be an active immunotherapy in addition to its demonstrated ability to ablate tumors, this drug may offer greater benefit to cancer patients than initially contemplated. Dr. Goll...

CEL-SCI Corporation Reports 2009 Second Fiscal Quarter Financial Results

...rporation develops immune-based cancer and infectious disease therapies. Its primary product candidate is Multikine, a next-generation, comprehensive immunotherapy that targets newly diagnosed head and neck cancer. Multikine is cleared by the FDA and the Canadian regulators for a global Phase III clinical trial ...

Immunotherapy effective against neuroblastoma in children

...rs reported their findings the first to show that immunotherapy could be effective against childhood cancer onlin... given the standard treatment (retinoic acid) plus immunotherapy (the antibody plus immune-boosting substances), wh... After two years, 66 percent of individuals in the immunotherapy group were living free of cancer compared to 46 pe...

Immune Therapy May Aid Kids With Neuroblastoma

...rvived without a relapse reached 66 percent in the immunotherapy groups, compared with 46 percent among those who d...survival after two years reached 86 percent in the immunotherapy cohort and 75 percent among those who got standard... this disease," Yu said, "and we hope to make this immunotherapy available to more children with neuroblastoma." ...

Vaccine slows progression of skeletal muscle disorder

...ation in muscle cells so they could stay healthy longer," Kitazawa said. immunotherapy approaches such as vaccination are being extensively studied for Alzheimer'...ation of senile plaques, one of two signature Alzheimer's lesions. Although immunotherapy has shown some benefit in human clinical trials, there are significant safe...

Early Detection of Melanoma Plus Regular Skin Exams is Vital For Beating Disease

...reatment plan -- which may include surgical removal of the tumor with wide margins, usually including the affected regional lymph nodes; chemotherapy; immunotherapy or radiation therapy -- is often indicated. When the tumor has spread to a distant site, such as the lung, brain or other organ, this is consider...