Silenced genes as a warning sign of blood cancer
In many types of cancer, parts of the genetic material of tumor cells are switched off by chemical labels called methyl groups. This kind of methyl labeling ranges among the epigenetic changes that do not change the sequence of DNA building blocks. Such labels are found particularly often in genes...
'Suicide' Genes Help Slow Ovarian Tumor Growth in Mice
Treatment could be tested in women within 18 to 24 months, expert suggests
THURSDAY, July 30 (HealthDay News) -- Treatment with "suicide" genes
slowed ovarian tumor growth in mice and may one day offer a way to treat late-stage ovarian cancer in women, U.S. scientists say.
Nanoparticle-delivered 'Suicide' Genes Slowed Ovarian Tumor Growth
Potential late-stage ovarian cancer therapy; currently none available; Diphtheria-encoding genes
delivered to tumor site by nanoparticles; Laboratory research; possible human trials about 18 months away
Philadelphia (Vocus) July 29, 2009 -- Nanoparticle delivery of diph...
Five Hypertension Genes Found in Black Americans
Could be targets for new treatments, researchers say
FRIDAY, July 17 (HealthDay News) -- Federal researchers have identified five genetic variants associated with high blood pressure in black Americans that could hopefully become targets for therapy to prevent and treat this major risk...
Australian researchers identify genes that cause melanoma
Scientists from the Queensland Institute of Medical Research (QIMR) have found two new genes
that together double a person's risk of developing melanoma.
As part of an international study, a team at QIMR, led by Professors Nick Hayward and Grant Montgomery, studied the genes
of almost 6,000 pe...
Hundreds of Genes Could Be Linked to ADHD
Variations would explain different attention-disorder symptoms, study suggests
THURSDAY, June 25 (HealthDay News) -- Hundreds of gene variations that may be associated with attention-deficit/hyperactivity disorder (ADHD) have been identified by U.S. researchers.
Many of these genes...
No Benefit in Testing for Genes Linked to Leg Clots
Taking precautions best way to avoid deep vein thrombosis, report says
TUESDAY, June 16 (HealthDay News) -- There's no proof that genetic testing can help prevent the potentially dangerous blood clots called deep vein thrombosis, a new U.S. government report shows.
The presence of ...
Dad's Genes May Play Greater Role Than Thought
Data on 'packaging' in sperm cells may also help assess infertility,,
MONDAY, June 15 (HealthDay News) -- Biologists say they have discovered a clever packaging scheme that allows the genetic material in sperm to have far more influence over development of a fertilized egg than had bee...
Interleukin Genetics to Present Research Linking Perilipin Genes to Diet Response at the ADA Annual Meeting
WALTHAM, Mass., June 5 /PRNewswire-FirstCall/ -- Interleukin Genetics, Inc. (NYSE Amex: ILI ) announced today that Nazneen Aziz, Ph.D., Vice President of Research and Development, will present findings that highlight significant associations between perilipin gene variants and response to weig...
Researchers Spot Genes Linked to Testicular Cancer
Discovery could help determine which men are at increased risk, scientists say
MONDAY, June 1 (HealthDay News) -- U.S. scientists say they've identified key gene variants tied to an increased risk of testicular cancer.
They said the findings are an important step toward understandi...
Cancer cells need normal, nonmutated genes to survive
BOSTON, Mass. (May 28, 2009) Corrupt lifestyles and vices go hand in hand; each feeds the other. But even the worst miscreant needs customary societal amenities to get by. It's the same with cancer cells. While they rely on vices in the form of genetic mutations to wreak havoc, they must sustain ...
Swine Flu Genes Went Undetected for Years: Report
Sequencing of virus' genome should make finding a vaccine easier, CDC says
FRIDAY, May 22 (HealthDay News) -- Many of the genes
that make up the new H1N1 swine flu virus have been circulating undetected in pigs for more than a decade, researchers reported Friday.
Scientists at the U...
ACMG Joins Lawsuit Challenging Patents on Breast Cancer Genes; Genes Are Naturally Occurring Substances and Should Not Be Patented, Says American College of Medical Genetics
BETHESDA, Md., May 12 /PRNewswire-USNewswire/ -- The American College of Medical Genetics (ACMG) has joined the Association for Molecular Pathology, the College of American Pathologists, and the American Society for Clinical Pathology in a lawsuit filed today charging that patents on the human gen...
Dark hair? Don't burn? Your genes may still put you at risk for melanoma
DENVER New genetic research suggests that the traditional risk factors for melanoma may not be as helpful in predicting risk in all people as previously thought, according to data presented at the American Association for Cancer Research 100th Annual Meeting 2009.
"Traditionally, a clinician ...
Progen Technology Switches on Cancer Fighting Genes and Inhibits Tumor Growth
BRISBANE, Australia, April 20 /PRNewswire-FirstCall/ --Progen Pharmaceuticals Limited (ASX: PGL; Nasdaq: PGLA ) has released data that shows its epigenetic technology successfully inhibits tumor growth.
The results of the pre-clinical experiments, presented by Progen's collaborators at the ...
Rearrangements of multifunctional genes cause cancer in children and young people
A doctoral thesis presented at the Sahlgrenska Academy, University of Gothenburg, Sweden, shows that three genes
that lie behind a number of malignant tumour diseases are normally involved in several fundamental processes in the cell. This may be the reason that the tumours arise early in life and...
2 Genes Implicated in Autism
Finding might lead to better diagnosis, treatment, study suggests
MONDAY, Feb. 9 (HealthDay News) -- Multiple, interacting genetic risk factors may influence the severity of autism, a new study suggests.
Massachusetts Institute of Technology researchers said they've pinpointed two g...
New genes involved in acute lymphoblastic leukemia play fundamental role in prognosis of the disease
This release is available in Spanish .
The inactivity or "silence" of certain genes
plays a fundamental role in the prognosis of acute lymphoblastic leukemia as well as in response to treatment, according to the results of research involving a team made up of specialists from the Universi...
Penn study finds link between Parkinson's disease genes and manganese poisoning
PHILADELPHIA A connection between genetic and environmental causes of Parkinson's disease has been discovered by a research team led by Aaron D. Gitler, PhD, Assistant Professor in the Department of Cell and Developmental Biology at the University of Pennsylvania School of Medicine. Gitler and co...
In Kids, Genes May Affect Leukemia Treatment
Finding could help tailor therapy regimen to individuals, experts say
TUESDAY, Jan. 27 (HealthDay News) -- Genetic variations appear to affect the way children respond to treatment for lymphoblastic leukemia, researchers report.
Although about 80 percent of children suffering from t...
Popular or Not? Your Genes May Help Decide
Twins study suggests that sociability, shyness might be hidden in DNA
MONDAY, Jan. 26 (HealthDay News) -- Tucked away in the twisted strands of DNA that make you human are genes
that may determine whether you are sociable or shy.
A new study comparing the two types of twins shows th...
Common Genes Link Bipolar Disorder, Schizophrenia
Large Swedish study suggests reappraisal of conditions as distinct entities needed
FRIDAY, Jan. 16 (HealthDay News) -- Bipolar disorder and schizophrenia appear to share common genetic causes, a new, far-reaching Swedish study concludes.
In analyzing three decades of generationa...
UCSF Researchers Use New Tools to Move in on Cancer Susceptibility Genes
UCSF researchers have used a new strategy to study inherited susceptibility for skin cancer in mice. In the process, they have identified a network of genes
that may play a key role in controlling this susceptibility. The technique, the scientists say, could be used to identify such genes
9 Genes Are Linked to Alzheimer's
Finding also bolsters tie between vitamin D and the brain disease
WEDNESDAY, Jan. 7 (HealthDay News) -- Researchers have identified nine genes
that might make people more likely to develop Alzheimer's disease.
In addition, they confirmed earlier reports that a variation in the vitam...
Few DNA repair genes maintain association with cancer in field synopsis
Variants of numerous DNA repair genes
initially appeared to be statistically significantly associated with cancer risk in epidemiological studies. When the data from individual studies are pooled, however, few DNA repair gene variants appear truly associated with increased cancer risk, according t...
Studies on Smoking Genes and Transcriptional Control of Chronic Fatigue Syndrome Revealed in Molecular Medicine
Smokers who have an easier time quitting may have the benefit of specific genes
that can foster success, according to a new study by a team of federal scientists at the National Institute on Drug Abuse.
Manhasset, NY (Vocus) December 23, 2008 -- Smokers who have an easi...
SNPs of ABC transporter genes linked to lung cancer risk
Individuals with particular variants of certain genes
involved in metabolizing the most potent carcinogen found in cigarette smoke have an increased risk of developing lung cancer. That is the conclusion of a new study published in the February 1, 2009 issue of CANCER , a peer-reviewed journal of...
11 New Cholesterol Genes Identified
Could be targets for drug treatment, researchers note
MONDAY, Dec. 8 (HealthDay News) -- An international research team that screened the genes
of more than 40,000 people has identified 11 more regions that govern levels of blood fats such as LDL cholesterol and triglycerides.
Researchers ID Suite of Genes in Aging Process
Biomarkers could provide scientific baseline for anti-aging drug trials, study says
WEDNESDAY, Nov. 19 (HealthDay News) -- Genetic biomarkers that are highly accurate in determining physiological age have been identified by researchers at California's Buck Institute for Age Research, w...
Cold Spring Harbor science teams identify 13 new tumor-suppressor genes in liver cancer
Over the years, hunting for cancer-related genes
and understanding how they work has been an important, although time-consuming, exercise. At Cold Spring Harbor Laboratory (CSHL), five different research groups have now combined their expertise to speed up the rate of discovering cancer-related g...
Type-1 diabetes not so much bad genes as good genes behaving badly, Stanford research shows
STANFORD, Calif. Investigators combing the genome in the hope of
finding genetic variants responsible for triggering early-onset diabetes
may be looking in the wrong place, new research at the Stanford
University School of Medicine suggests.
Early-onset diabetes, also known as type-1 diabet...
Researchers Find More Genes Linked to Lung Cancer
Discovery could lead to new targeted, individualized treatments, experts say
WEDNESDAY, Oct. 22 (HealthDay News) -- Researchers have identified 26 genes
associated with the most common type of lung cancer, adenocarcinoma -- more than doubling the number of genes
known to play a role i...
New candidate genes for schizophrenia identified
Schizophrenia is a severe psychiatric disease characterized by disorganized behavior, delusions and hallucinations. Sadly, there is no clear understanding of its cause.
Now, in a collaborative study, UCLA and Dutch researchers have identified three new candidate genes
for schizophrenia that...
Blood Cell Genes May Signal Heart Disease
Small study finds their levels correlate with cardiovascular trouble
WEDNESDAY, Oct. 8 (HealthDay News) -- A test that measures the activity of genes
in white blood cells might someday help doctors determine the proper treatment when someone complains of chest pain, researchers report....
UNC study: Parenting can override effect of genes in how babies respond to stress
CHAPEL HILL Everyone gets stressed, even babies.
Now, it appears how infants respond to stress is linked to if they have a particular form of a certain gene, according to a new study from the University of North Carolina at Chapel Hill.
Just as significantly, researchers say they have als...
Type 1 diabetes may result from good genes behaving badly
WHAT: New research from Stanford University scientists suggests that type 1 diabetes, an autoimmune disease that develops in children and young adults, may not be due to bad genes
but rather to good genes
Because type 1 diabetes typically runs in families, scientists have look...
Beyond PTEN: Alternate genes linked to breast, thyroid and kidney cancer predisposition
A new discovery may lead to more effective screening and treatment for patients with a difficult to recognize syndrome characterized by tumor-like growths and a high risk of developing specific cancers. The research, published by Cell Press in the August 7 issue of the American Journal of Human G...
Researchers Find Genes That Influence West Nile Virus
Could lead to way to prevent, treat disease in humans
WEDNESDAY, Aug. 6 (HealthDay News) -- Researchers have zeroed in on more than 300 human genes
that appear to impact West Nile virus infection of human cells.
Finding ways to interfere with how these genes
work may provide ways to...
Identification of 5 genes involved in the metastasis of breast tumors to the lung
This release is available in Spanish .
The identification of five genes
involve in the metastasis of breast tumours to the lung is the principal finding of a scientific team made up of two bodies from the University of Navarra, the Applied Medical Research Centre (CIMA) and the University H...
Genome sequence of lancelet shows how genes quadrupled during vertebrate evolution
Berkeley The newly sequenced genome of a dainty, quill-like sea creature called a lancelet provides the best evidence yet that vertebrates evolved over the past 550 million years through a four-fold duplication of the genes
of more primitive ancestors.
The late geneticist Susumu Ohno argued in...