Expression in Medical News

MDS Nordion Submits Expression of Interest Proposal to Government of Canada on Medical Isotope and Generator Production

MAPLE Reactors Could Solve the Isotope Crisis within 24 months OTTAWA, July 30 /PRNewswire-FirstCall/ - MDS Nordion, a leading provider of medical isotopes and radiopharmaceuticals, has submitted a Proposal to the Government of Canada's Expert Review Panel on Medical Isotope and Technetium-99...

Covance to Acquire Seattle-Based Gene Expression Laboratory from Merck & Co., Inc.

PRINCETON, N.J., July 29 /PRNewswire-FirstCall/ -- Covance (NYSE: CVD ) today announced it has entered into a definitive agreement with Merck & Co., Inc. relating to the supply of genomic analysis services. Under the terms of the agreement Merck has committed to ...

Mapping gene expression with Gene Expression Atlas

Hinxton, 15 June 2009 Today, researchers at the European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI) launch a new database, the Gene Expression Atlas, which allows scientists to search and compare gene expression data at unprecedented detail and scope. Observing how...

Turning down gene expression promotes nerve cell maintenance

February 2, 2009, Cambridge, UK Anyone with a sweet tooth knows that too much of a good thing can lead to negative consequences. The same can be said about the signals that help maintain nerve cells, as demonstrated in a new study of myelin, a protein key to efficient neuronal transmission. ...

Tau protein expression predicts breast cancer survival -- though not as expected

SAN ANTONIO - Expression of the microtubule-binding protein Tau is not a reliable means of selecting breast cancer patients for adjuvant paclitaxel chemotherapy, according to research led by The University of Texas M. D. Anderson Cancer Center. Presented today, Dec. 13, at the CRTC-AACR San Ant...

Estrogen and progesterone receptor isoforms expression in the stomach of Mongolian gerbils

We have previously shown that E2 and P4 have clear and distinct effects on inflammatory response and gastric epithelial changes during early H. pylori infection. Recently, Ohtani et al., have shown a protective role of E2 administration in H. pylori-infected InGas mice. Other studies have demonstr...

Longs Drug Stores Confirms Receipt of Expression of Interest from Walgreens

WALNUT CREEK, Calif., Sept. 14 /PRNewswire-FirstCall/ -- Longs Drug Stores Corporation ("Longs") (NYSE: LDG ) today confirmed that it had received an unsolicited, non-binding expression of interest from Walgreens. The expression of interest suggests an offer of $75.00 per share in cash for al...

CSHL scientists correlate enzyme expression levels with chemotherapy drug response

Why do cancer patients develop resistance to chemotherapy drugs, sometimes abruptly, after a period in which the drugs seem to be working well to reduce tumors or hold them in check? Although largely a mystery to scientists, the result when this occurs is all too familiar: patients relapse and in...

Lack of CHFR gene expression sets stage for breast cancer

ANN ARBOR, Mich. A University of Michigan study reveals in detail how breast cells produce new cells that are predisposed to become cancerous, unless they receive the protective action of the CHFR gene. CHFR expression is missing in more than a third of breast cancers. Analysis of this gene i...

MicroRNA controls expression of oncogenes

A new study demonstrates that microRNAs can modulate the expression of well known tumor-specific oncogenic translocation proteins and may play a significant role in some human cancers. The research, published by Cell Press in the June issue of the journal Cancer Cell, is likely to lead to new stra...

Is increased Slug expression associated with the progression to esophageal cancer?

Real-time reverse transcription-polymerase chain reaction (RT-PCR), semi-quantitative immunohistochemistry and tissue array reveal that the progression to adenocarcinoma is associated with increased Slug expression and this may represent a mechanism of E-cadherin silencing. This study, perform...

COX-2 expression is marker for cancer development in some benign breast biopsies

ROCHESTER, Minn. -- Its a good news, bad news situation. Some women who have a breast biopsy are told that while they dont have cancer, they do have atypical hyperplasia -- cells that arent quite normal and might become cancerous someday. This happens to one-fourth of women undergoing breast biops...

Gene expression differences between Europeans and Africans affect response to drugs, infections

Differences in gene expression levels between people of European versus African ancestry can affect how each group responds to certain drugs or fights off specific infections, report researchers from the University of Chicago Medical Center and the Expression Research Laboratory at Affymetrix Inc....

NEJM editorial on significance and limitations of new lupus gene expression research

Some 1.5 million Americans, most of them women, suffer from lupus, a disease where the persons immune system attacks the bodys own tissue. This week marks a significant step forward in understanding how the disease works with the online publication of four new studies identifying genes involved in...

How does Fu-Zheng-Jie-Du-Decoction act on PTEN expression in hepatocellular carcinoma?

Many hepatocellular carcinoma (HCC) patients in China may be treated with Traditional Chinese medicine (TCM). Some say it works, others doubt its effectiveness. These stated that a research group in China had found TCM can down-regulate the expression of PTEN in HCC, which may suppress tumor cell ...

iNOS expression may links chronic biliary inflammation to malignant transformation

It is well known that chronic biliary inflammation is a risk factor for biliary carcinogenesis. However, the molecular mechanisms of biliary carcinogenesis as a consequence of chronic biliary inflammation remain unclear. Inducible nitric oxide synthase (iNOS) is induced in inflamed tissues and ...

Biolytix to Offer Industrial Gene Expression Analysis and Genotyping Services Using Affymetrix' GeneChip(R) Technology

WITTERSWIL, Switzerland, November 29 /PRNewswire/ -- Biolytix AG ( http://www.biolytix.ch ) signed a service provider agreement with Affymetrix UK Ltd ( http://www.affymetrix.com ) and offers genomic analysis services for the academic and industrial R&D community under conditions compliant wit...

Flip-flopping gene expression can be advantageous

One gene for pea pod color generates green pods while a variant of that gene gives rise to the yellow-pod phenotype, a feature that helped Gregor Mendel, the 19th century Austrian priest and scientist, first describe genetic inheritance. However, many modern-day geneticists are focused on the stra...

New study shows that therapeutic gene expression can be sustainable for 1 year

Researchers at the Board of Governors Gene Therapeutics Research Institute at Cedars-Sinai Medical Center have shown for the first time that it is possible to sustain therapeutic gene expression in the central nervous system for up to a year, even in the presence of an anti-viral immune response m...

Altered expression of ultraconserved noncoding RNAs linked to human leukemias and carcinomas

A new study provides evidence that noncoding RNAs and interactions between noncoding genes play a much greater role in human cancer than was previously understood. The research, published by Cell Press in the September issue of the journal Cancer Cell, may be useful for identifying tumor-specific ...

The Healing Power of Art, Dance and Expression

CHICAGO, July 31 /PRNewswire/ -- The calming strokes of a paint brush and the expression of dance and movement have an incredible ability to soothe, heal and inspire. Experiential and expressive therapies, such as art therapy, dance and movement therapy and equine therapy, have...

Unspoken memories of Holocaust survivors find silent and nonpathological expression

A faculty member of the Department of Sociology and Anthropology at the University of Haifa presented the results of a new research at an international Holocaust conference held at the University of Haifa. The findings presented: Unspoken memories of Holocaust survivors find silent and non-pat...

War and Musculoskeletal Injury Prompt Artistic Expression

The American Academy of Orthopaedic Surgeons seeks war injury related art ROSEMONT, Ill., June 10 /PRNewswire-USNewswire/ -- The following was released today by the American Academy of Orthopaedic Surgeons: WHAT: Wartime experiences not only affect the military personnel and their lov...

War and Musculoskeletal Injury Prompt Artistic Expression

The American Academy of Orthopaedic Surgeons seeks war injury related art ROSEMONT, Ill., April 30 /PRNewswire-USNewswire/ -- Wartime experiences not only affect the military personnel and their loved ones, but the physicians and medical teams who treat them. As a tribute to injured troops ...

Synthetic gene circuit allows precise dosing of gene expression

HOUSTON - Researchers have crafted a gene circuit that permits precise tuning of a gene's expression in a cell, an advance that should allow for more accurate analysis of the gene's role in normal and abnormal cellular function. This gene "dosing effect" is achieved by installing a negative fee...

K-State helps nursing home staff become comfortable with residents' sexual expression

MANHATTAN "Do not disturb" signs aren't just for newlyweds anymore. They are also a way to give nursing home residents some privacy for sexual expression, according to Kansas State University aging experts. "By law you can't always lock a room, but you can offer residents some privacy," sai...

Scientists identify key roadblock to gene expression

A team of scientists has provided, for the first time, a detailed map of how the building blocks of chromosomes, the cellular structures that contain genes, are organized in the fruit fly Drosophila melanogaster. The work identifies a critical stop sign for transcription, the first step in gene e...

Allegro Diagnostics Closes $4 Million Round to Develop and Commercialize Lung Cancer Molecular Diagnostics Based on Gene Expression

Jerome Brody, MD Joins Company as Chief Scientific Officer BOSTON, March 7 /PRNewswire/ -- Allegro Diagnostics, a leader in the field of molecular diagnostics for lung cancer, has announced completion of $4 million in Series A financing. Kodiak Venture Partners led the round and was joi...

High zinc status in lung cells slows growth and induces DNA damage-induced gene expression

Researchers at the University of Maryland at College Park have discovered that Normal Human Bronchial Epithelial (NHBE) cells cultured in medium with elevated zinc level, at the high end of plasma zinc attainable by oral supplementation, demonstrated inhibition of cell growth, up-regulation of gro...

Jefferson scientists uncover role of cancer stem cell marker: controlling gene expression

(PHILADELPHIA) Scientists at Jeffersons Kimmel Cancer Center in Philadelphia have made an extraordinary advance in the understanding of the function of a gene previously shown to be part of an 11-gene signature that can predict which tumors will be aggressive and likely to spread. The gene, USP22,...

Gene Expression in Blood may Hold Clues About Chronic Fatigue Syndrome

Researchers have linked gene expression with the disease process that lies behind chronic fatigue syndrome (CFS). The new study has found that blood may hold key information about what goes on in the brain of CFS patients. CFS is marked by severe, chronic mental and physical exhaust...

New Platform for Regulating Expression of Therapeutic Genes Unveiled

A new platform for regulating the expression of therapeutic genes, which will have major implications for gene and cell therapy, was presented today at the 10th Annual Meeting of the American Society of Gene Therapy (ASGT) in Seattle. Carefully regulating gene expression is crucial to the ...

Accuracy of Gene Expression Test for Heart Transplant Patients Confirmed

For many Americans living with a heart transplant, invasive heart-muscle biopsies that check for organ rejection are a fact of life. // Now, a simple blood test that analyzes a patient’s genes has been evaluated by leading transplant centers and shows that it can accurately detect the absence...

Telomerase Expression Linked To Body Mass

Telomerase is an enzyme that is known to have healing properties. It was earlier considered that the lifespan of an organism and the amount of telomerase expressed were// related but it is now been linked to body mass. Telomerase is also known to increase the rate of cancer. Vera Gorbunova, ...

Brain protein expression can be damaged with prolonged alcohol exposure

Researchers at the University at Buffalo probing into the effects of alcohol on the brain, and studying the zebra fish as a model, have zeroed in on many proteins in the central nervous system//, that are impacted negatively with severe alcohol exposure. The scientists were now confident about the ...

New Diagnostic Tool Uncovered Gene Expression Patterns in Recessive Genetic Disorders

A new diagnostic method has been discovered by two scientists Vivian Cheung and Warren Ewens from the University of Pennsylvania to study //medical disorders that are recessively inherited. Gene expression patterns in carriers of genetic diseases would differ significantly and this new diagnost...

Innocent Expression of Compassion, Children Draw For HIV kids

A function was held at Al Bustan Palace Hotel to place on record the exemplary work of art by students from grades V to XII // , as part of the effort by Oman in the ‘Unite for children Unite against Aids’ campaign initiated world-wide by the Unicef and UNAids. ‘Unite for Children Unite Agai...

Protein Expression to Serve as Marker for Head and Neck Cancer

Recent studies have revealed that the blood of patients with head and neck cancer have some unique patterns of protein expression which could serve as a screening test for this highly aggressive cancer. // Studies comparing protein expression in 78 patients with head and neck cancer to 68 healt...

High expression of interferon induces lupus disease

Scientists had been able to find a biomarker that will help in medical practitioners to diagnose lupus disease in their early state only for effective treatment.// Lupus is a condition that happens when the body’s tissues are affected by the body’s own immune system. Patients affected with lup...

How Blood Flow Dictates Gene Expression

Researchers at the University of Pennsylvania School of Medicine have pinpointed a key regulatory protein that translates blood flow into gene expression. The// investigators showed that in a model of mouse embryonic development a transcription factor called Klf2, which resides in cells that line b...