Enzyme in Medical News

Weight-Loss Enzyme Identified

Researchers may have found a way to curb hunger, rev up energy TUESDAY, July 21 (HealthDay News) -- Reducing levels of a brain enzyme may curb appetite and boost energy, thereby helping people to control their weight, says a new study. Prolylcarboxypeptidase (PRCP) regulates the al...

LSUHSC research identifies enzyme that makes survival molecule for key vision cells

New Orleans, LA Research lead by Dr. Nicolas Bazan, Boyd Professor and Director of the Neuroscience Center of Excellence at LSU Health Sciences Center New Orleans, identifying an enzyme that makes neuroprotectin D1 which specifically and selectively protects retinal cells key for vision, will be ...

Lung Enzyme Both Friend and Foe

MMP-12 contributes to emphysema, but also guards against infection, study shows WEDNESDAY, June 17 (HealthDay News) -- An enzyme involved in the development of emphysema also defends the lungs against bacterial infection, a new study finds. It had been thought that the only thing ma...

High Activity, Plant Based Diamine Oxidase Enzyme Introduced by Bio-Research Products

NORTH LIBERTY, Iowa, June 15 /PRNewswire/ -- Bio-Research Products announced today the first commercial, plant-based diamine oxidase (DAO). Dr. Bryce Cunningham, President and Chief Technology Officer of Bio-Research, reports that this new diamine oxidase is orders of magnitude more active than DA...

Video: CREON(R) (Pancrelipase) Delayed-Release Capsules First and Only Pancreatic Enzyme Product to Receive FDA Approval Under New Guidelines

- Therapy is medically-necessary for thousands of patients with exocrine pancreatic insufficiency due to cystic fibrosis or other conditions - MARIETTA, Ga., May 1 /PRNewswire/ -- Solvay Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) approved CREON(R) ...

Reversing effects of altered enzyme may fight brain tumor growth

An international team of scientists from the Moores Cancer Center at the University of California, San Diego, the University of North Carolina and several institutions in China have explained how a gene alteration can lead to the development of a type of brain cancer, and they have identified a co...

Durability of dental fillings improves if the enzyme activity of teeth is inhibited

Composite dental fillings have one problematic feature, in that the bond between the filling and the dental tissue deteriorates over time in fact, sometimes by as much as 50 per cent in one year. As the bond deteriorates, it may allow bacteria to enter and this brings a high risk of further tooth...

Unique Glutathione Reductase Enzyme Introduced by Bio-Research Products

NORTH LIBERTY, Iowa, Feb. 3 /PRNewswire/ -- Bio-Research Products announced today that it will offer a high specific activity lyophilized grade of the enzyme Glutathione Reductase (GR). Dr. Bryce Cunningham, President and Chief Technology Officer of Bio-Research, reports that this is the first...

Scientists ID Enzyme Causing Brain Cell Death

Findings could offer new therapies for neurodegenerative diseases WEDNESDAY, Dec. 10 (HealthDay News) -- An enzyme believed to play a role in the death of neurons in the brains of patients with Alzheimer's and other neurodegenerative diseases has been identified by U.S. researchers. ...

Researchers discover new enzyme in cancer growth

OKLAHOMA CITY While studying the mechanics of blood clots, researchers at the University of Oklahoma Health Sciences Center discovered a new enzyme that not only affects the blood, but seems to play a primary role in how cancer tumors expand and spread throughout the body. The research appeared i...

Broccoli compound targets key enzyme in late-stage cancer

Berkeley -- An anti-cancer compound found in broccoli and cabbage works by lowering the activity of an enzyme associated with rapidly advancing breast cancer, according to a University of California, Berkeley, study appearing this week in the online early edition of the journal Proceedings of the...

IDO2 an active enzyme to target in pancreatic cancer

(PHILADELPHIA) An enzyme that is overexpressed in pancreatic cancer cells may hold the key to successfully treating the disease with targeted immunotherapy, researchers from Thomas Jefferson University reported at the 2008 Annual Meeting of the Southern Surgical Association. Previous data show...

CSHL scientists correlate enzyme expression levels with chemotherapy drug response

Why do cancer patients develop resistance to chemotherapy drugs, sometimes abruptly, after a period in which the drugs seem to be working well to reduce tumors or hold them in check? Although largely a mystery to scientists, the result when this occurs is all too familiar: patients relapse and in...

St. Jude Study Reveals a New Function for an Old Enzyme in Fatal Childhood Disease

A ubiquitous housekeeping enzyme has been found to play a major role in keeping the bone marrow environment healthy so it can nurture hematopoietic stem cells MEMPHIS, Tenn., July 7 /PRNewswire-USNewswire/ -- The lack of a single protein usually thought of as a run-of-the-mill enzyme that he...

Scientists ID Enzyme That Allows Dysentery Amoeba to Hide

Finding could lead to more effective treatments for diarrhea worldwide, study says THURSDAY, June 19 (HealthDay News) U.S. researchers say they've identified an enzyme that may help dysentery-causing amoeba evade the immune system. The finding may help lead to new ways to fight d...

Novel enzyme inhibitor paves way for new cancer drug

(PHILADELPHIA) Combining natural organic atoms with metal complexes, scientists at The Wistar Institute have developed a new type of enzyme inhibitor capable of blocking a biochemical pathway that plays a key role in cancer development. Based on studies in human melanoma cells, the research p...

Blood pressure enzyme can have tumor-sensing role

By increasing production of a blood pressure-regulating enzyme in mice, researchers have found they can enhance the mouse immune system's ability to sense tumor growth. When scientists at Emory University School of Medicine engineered mice that make more angiotensin-converting enzyme in white b...

AGI Dermatics Data Indicates 8 Oxo-Guanine Repair Enzyme OGG1 Encapsulated in Liposomes, Reduces MMP-1, Increases Collagen and Enhances DNA Repair

Clinical Data Presented at the 66th Annual Meeting of the American Academy of Dermatology FREEPORT, N.Y., Feb. 11 /PRNewswire/ -- AGI Dermatics presented clinical research that indicates the 8-oxo-guanine DNA glycosylase (OGG1) encapsulated in liposomes is an effecti...

First look at an enzyme target for antibacterial and cancer drugs

The veil has finally been lifted on an enzyme that is critical to the process of DNA transcription and replication, and is a prime target of antibacterial and anticancer drugs. Researchers with the U.S. Department of Energys Lawrence Berkeley National Laboratory (Berkeley Lab) and the University o...

McGill researchers link enzyme to breast cancer malignancy

This release is available in French . McGill University researchers have uncovered the crucial role played by the enzyme focal adhesion kinase (FAK) in the onset of breast cancer. The research, led by Dr. William Muller along with colleagues from McGill and the Beatson Institute for Cancer...

Telomerase enzyme structure provides significant new target for anti-cancer therapies

(PHILADELPHIA) Inappropriate activation of a single enzyme, telomerase, is associated with the uncontrollable proliferation of cells seen in as many as 90 percent of all of human cancers. Since the mid-1990s, when telomerase was first identified in human tumors, scientists have eyed the enzyme as...

Role of a key enzyme in reducing heart disease identified

Virginia Commonwealth University researchers have identified the role of a key enzyme called CEH in reducing heart disease, paving the way for new target therapies to reduce plaques in the arteries and perhaps in the future, help predict a patients susceptibility to heart disease. Furthermore, ...

Tumors use enzyme to recruit regulatory T-cells and suppress immune response

One way tumors fly under the radar of the immune system is by using IDO, an enzyme used by fetuses to help avoid rejection, to recruit powerful regulatory T cells that turn down the immune response, researchers say. It was known tumors assemble a protective barrier of regulatory T cells, or Tre...

UCSD study reveals the regulatory mechanism of key enzyme

Research conducted at the University of California, San Diego (UCSD) School of Medicine has shed new light on the structure and function of one of the key proteins in all mammalian cells, protein kinase A (PKA), an enzyme which plays an essential role in memory formation, communication between ner...

UCSD study reveals the regulatory mechanism of key enzyme

Research conducted at the University of California, San Diego (UCSD) School of Medicine has shed new light on the structure and function of one of the key proteins in all mammalian cells, protein kinase A (PKA), an enzyme which plays an essential role in memory formation, communication between ner...

Structure of TB Enzyme Points the Way to New Drugs: Study

Swiss scientists said Monday that they have further evidence to suggest that an enzyme secreted by the microbe that causes tuberculosis would make a promising target for new drugs to combat the deadly infectious disease. The Swiss team first identified the enzyme, protein kinase G (PknG), ...

Alzheimers Disease Enzyme may Interfere With Brain Function

An enzyme involved in the formation of the amyloid-beta protein associated with Alzheimers disease can also alter the mechanism by which signals are transmitted between brain cells , the disruption of which can cause seizures. These findings from researchers at the MassGeneral Institute for...

Alzheimer's-associated Enzyme Linked to Seizures

Boffins have found that an enzyme beta-secretase or BACE, involved in the formation of the amyloid-beta protein linked with Alzheimer's disease can also alter neural activity in the brain , whose disruption might lead to seizures. The study might put light on the high occurrence of seizures...

Blocking Enzyme Can Treat Breast Cancer

Canadian scientists claim to have found a treatment, which could block the action of an enzyme that fuels the growth of breast cancer. The enzyme PTP1B appears to fuel tumor growth and drugs that block this enzyme may be useful in treating the disease. About 40 percent of human breast cancers...

Scientists Develop Method to Track Immune System Enzyme in Live Animals

Scientists supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) at the National Institutes of Health have created two mouse strains that will permit researchers to trace, in a live animal, the activity of an enzyme believed to play a crucial role both in t...

A Shot in the Arm for Cancer Enzyme Research

Sydney- In what is being termed as a breakthrough in cancer research,// scientists from the Children's Medical Research Institute have cracked the composition of the cancer enzyme, telomerase, a constant in more than 85% of all cancers. This finding could pave the way for the design of precise drug...

Viral Enzyme Recruited in Fight Against Ear Infection

Parents might one day give their children a weekly treatment with a nasal spray of virus enzymes to prevent them from getting a severe middle //ear infection, based on results of a study. Such a treatment would kill the disease-causing bacteria without the use of antibiotics, thereby avoiding the p...

Fetal Heart-Cell Enzyme and Onset of Heart Failure

In almost all forms of heart failure, the heart begins to express genes that are normally only expressed in the fetal heart//. Researchers have known for years that this fetal-gene reactivation happens, yet not what regulates it. Now, investigators at the University of Pennsylvania School of Medici...

Anti-Aging Powers of Enzyme Sirtuins

In the recent years, scientists discovered a family of enzymes called sirtuins, which can dramatically extend life in organisms// as diverse as yeast, worms, and flies. Now, a new study from scientists at The Wistar Institute points to another strategy for activating sirtuins to unleash their...

Sentry Enzyme Blocks Two Paths to Parkinson’s Diseas

The degeneration of brain cells that occurs in Parkinson’s disease may be caused by either externally provoked cell death or internally initiated //suicide when the molecule that normally prevents these fatal alternatives is missing, according to studies in mouse models by investigators at St. Jude...

Suppression of Enzyme Delays a Type of Breast Cancer

Canadian researchers have disclosed that suppression of an enzyme called PTP1B stalls the advancement of a specific type of breast cancer//. This study was conducted on laboratory mice which were genetically modified to develop into a breast cancer condition of humans. This research headed by M...

Run Amok Enzyme Causes Same Problems in Both Humans and Fruit Flies

An enzyme found at elevated levels in several human cancers has been linked to abnormal tumor growth in fruit flies//, a discovery that provides a new model for understanding the link between stem cell biology and cancer, according to researchers. Using fluorescent staining and laser-scanning ...

Naturally Occurring Enzyme Can Break Down Key Part of Alzheimer's Plaques

Scientists have identified a naturally occurring enzyme that can break down a key component of the brain plaques characteristic of Alzheimer's disease.// The finding may provide researchers with new opportunities to understand what goes wrong in the brains of Alzheimer's patients and could one day ...

"Dynamic Energy Landscape" of enzyme in Catalysis

Complex protein molecules called enzymes catalyze specific biochemical reactions in cells. The traditional theory is that dynamic fluctuations//protein conformation or structure play a major role in enzyme catalysis. However, recent findings reveal that it is the "dynamic energy landscape" of the e...

Structure of DNA-modifying enzyme In Small Pox Determined

Researchers have determined the structure of DNA-modifying enzyme that could help fight the smallpox disease better. In a study published in the August 4 issue of Molecular Cell//, the researchers at the University of Pennsylvania School of Medicine have presented their findings on the structure o...