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Olivier Voinnet awarded 2009 EMBO Gold Medal

Heidelberg, Germany, 22 April 2009 - Olivier Voinnet from the CNRS Institute of Plant Molecular Biology in Strasbourg, France, is awarded the 2009 EMBO Gold Medal. The researcher receives this medal for his pioneering work on the mechanisms and roles of gene silencing via RNA in plants. With th...

Stopgap DNA repair needs a second step

...letters after the damaged site; only one repair enzyme is capable of performing this vital second step. These findings were published recently in the embo Journal . Understanding how this major form of DNA repair works can have significant clinical implications. Since defects in this process increase ...

Bioengineered proteins: Trial confirms new way to tackle cancer

...ing and growing has created a potentially powerful therapy for people with many different types of cancer. In a study published in the first issue of embo Molecular Medicine , Canadian researchers modified the tumour inhibiting protein, von Hippel-Lindau (VHL), and demonstrated that it could suppress tum...

Seven life scientists get research boost to set up in Europe

... embo Installation Grants are awarded annually and aim t...science in selected member states of the EMBC, the embo intergovernmental funding body. The EMBC Member St...nity. Grantees are integrated into the prestigious embo Young Investigator network, providing networking o...

Sour comes after a lemon has gone

...f acid stimulus. They call this new type of response as "off-response" of sour taste receptor. They reports their finding in an international journal, embo reports, on June 6, 2008. They investigated the PKD1L3-PKD2L1 channel activity stimulated by acid stimulus with calcium imaging method and electrop...

South African scientists access European research via EMBC agreement

...ing scientists from South Africa to participate in embo programmes and activities. The agreement also provides for some embo activities to occur in South Africa. embo recognises and fosters talented scientists, empowe...

The good and bad side of anti-cancer compounds

... will eventually come in, he says. HDAC inhibition isnt without side effects, however. And another recent paper from Hieberts lab, published in the embo Journal in March, provides some insight into how HDAC inhibition might cause liver damage. In that study, Hieberts group turned off HDAC3 in the l...

The structure of resistance

...s Descartes has solved the structure of two proteins that allow bacteria to gain resistance to multiple types of antibiotics, according to a report in embo reports this month. This work provides new clues as to how bacteria adapt to resist antibiotics and how to design new drugs that counteract this defen...

Lost in the middle: author order matters, new paper says

..., and the order in which the authors names are listed makes a big difference. The new findings appear in the Nov. 1 issue of the scientific journal embo Reports. OMRFs Jonathan Wren, Ph.D., is the first author on the paper, which is entitled The write position. In scientific circles, the long-accept...

How Candida albicans transforms from its normally benign form into life-threatening form

...r other diseases that damage the immunity of the individual. In two separate papers published last month in Developmental Cell and in August in the embo journal, the team of scientists led by Wang Yue, principal investigator at IMCB, have managed to reveal previously unknown mechanisms which are respon...

New prion protein discovered by Canadian scientists may offer insight into mad cow disease

... University of Alberta, Case Western Reserve University (Ohio) and the McLaughlin Research Institute (Montana). The research is published today in the embo Journal and represents a culmination of work initiated at the University of Toronto in 1999, and then continued more recently at the University of Alb...

Research Studies on Molecular Switches of Gene

...ciate member of the Department of Biochemistry at St. Jude. Brindle is senior author of a report on this work that appears in the June 20 issue of The embo Journal. CREB is like a plumber who turns on the water flow in a pipe system by using a certain tool, Brindle said. What we discovered is that th...

Preventing Cancer Without Killing Cells

...nducing senescence in aged cells may be sufficient to guard against spontaneous cancer development, according to a paper published online this week in embo reports//. It was previously unknown whether cellular senescence or programmed cell death – apoptosis – was the more important safeguard mechanism for...

A New Pathway To Deal With Sleeping Sickness

... A research published online in embo says that the parasite that is responsible for sleeping sickness can be// made inactive by a new pathway. Sleeping sickness is caused by Trypanosoma b...

Immune System Gears Up by Specific Enzymes

...author of a report on this work that appears in the January 24 issue of The embo Journal. The investigators performed their studies using animal cells...-3 to rein in these activated effector T cells. The current study in embo extends that finding by showing that cleavage of LAG-3 proteins on the surf...

Europeans Developing First-Ever Dengue Fever Vaccine

...the enzymes, which ultimately lead to blood loss, and have established an innovative treatment strategy. Their work was recently published in Nature’s embo Reports. According to the team of international researchers from France, the UK and Thailand, approximately 60 to 100 million people are at risk o...

Key Gene Controlling Eye Lens Development Identified

... the activity of a series of additional genes that cooperate to form the lens. A report on this work appears in the prepublication online issue of The embo Journal. Previously, the researchers were not able to address the gene’s possible role in mouse eye formation because inactivation of Six3 signi...

Key Gene Controlling Kidney Development Found

...f the St. Jude Genetics and Tumor Cell Biology Department. Oliver is senior author of a report on this finding that appears in the online issue of The embo Journal. 'Our discovery of Six2’s role in the developing kidney suggests that a similar mechanism exists in other developing organs,' said Miche...

Discovery of Agile Molecular Motors Could Aid in Treating Motor Neuron Diseases

...r motors are remarkably flexible in their behavior. In several further papers published in the Proceedings of the National Academy of Sciences and The embo Journal, Goldman and colleagues at the University of Illinois found that a “local delivery” motor, termed myosin V, moves cargo with a variable path s...
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