Stemedica Discovers Significant Breakthrough in the Use of Stem Cells and Stem Cell Factors for the Treatment of Retinal Degeneration
...oidal space prevented the animal's RPE cell's degeneration as well as preventing degeneration of the overlying photoreceptors proven by very objective erg
testing and histopathology. Secondarily, and even more interesting, is that the fellow contra lateral eye also showed a beneficial effect. This crosso...
QLT announces completion of Phase Ia safety trial of its synthetic retinoid product
...on of QLT091001 showed evidence of having corrected the biochemical defect in the retinoid cycle in light-sensing cells (rods) and appeared to restore erg
responses to light in both models of LCA.
About Leber's Congenital Amaurosis
LCA is an inherited degenerative retinal disease characterized ...
Tests Might Diagnose, Predict Prostate Cancer
...am developed a urine test that can identify particular gene fusions associated with prostate cancer. The gene fusions involve the TMPRSS2 gene and the erg
gene. This particular fusion is found in about 50 percent of men with prostate cancer and can be identified in urine, Groskopf said.
"This is an id...
U-M researchers discover traits of aggressive form of prostate cancer
...l gene fusion associated with prostate cancer occurs when one of two genes, erg
or ETV1, merges with a prostate-specific gene called TMPRSS2.
Before thi...te cells, and that it was found exclusively in cancers that did not involve erg
or ETV1 gene fusions.
For more information:
U-M Comprehensive Cancer ...
Dual functions of gene revealed, for better and for worse
...d sarcoma. American scientists showed in 2005 that erg
is mutated in more than half of all prostate cancers.
It was unclear, however, what function erg
normally performs in the human body and why it is ...n and fight infection.
The study suggests that erg
causes cancer by convincing normal cells to behave...
A Novel Technique That Detects "Cancer Genes" From The Breath Of Smokers
...androgen, and ERG, which is a potential oncogene, are located close to one another on chromosome 21. When fused, TMPRSS2 drives over-expression of the erg
gene. According to Perner, fusion can occur when the piece of DNA separating the genes breaks off and the genes merge (a process described as "fusion ...