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EMBL in Medical News

EMBL GeneCore purchases Genomatix's next generation sequencing data analysis solution

...ay, Chief Business Officer at Genomatix says: "We are very pleased that the embl has chosen our GMS and GGA. With our combined hardware/software approach, ...enomics Core Facility (GeneCore) is the in-house genomics service centre at embl equipped with state-of-the-art technologies required for functional genomic...

New research sheds light on the molecular basis of crib death

...ims of SIDS show alterations in those brainstem neurons that communicate using the signalling molecule serotonin. Cornelius Gross and his group at the embl Mouse Biology Unit modified the serotonin system of mice to understand the role of this signalling molecule in the brainstem. They overexpressed an im...

New revelations in epigenetic control shed light on breast cancer

...ion a mechanism of long-term regulation of a gene's activity, because the methylation marks are stable and maintained through cellular replication. embl researchers of the group of Frank Gannon, current director of the Science Foundation Ireland, now found out that methylation marks occur rapidly in br...

Life savers in the gut

...ns throughout the body. Since too little or too much iron is dangerous for our health a range of regulatory proteins tightly controls iron metabolism. embl scientists now assessed the role of two of these proteins, iron regulatory proteins 1 and 2 (IRPs), for the first time in living mice and found that t...

EMBL reaches north

...ersity, Sweden, officially launch their new Nordic embl Partnership for Molecular Medicine. The agreement ...ombining complementary strengths in the new Nordic embl Partnership equips us to tackle some of the most c...The partnership will result in the adoption of the embl model for international recruitment, staff turnove...

Boffins Identify Gene That can Protect Humans from Nephronopthisis

...m has discovered that mutations in the gene GLIS2 can lead to nephronopthisis (NPHP) in both humans and mice. Mathias Treier and his group at embl have paved way to develop innovative treatment for the disease by working on a mouse model. "Our mice show striking similarities with NPHP pat...

New Therapies for Kidney Diseases

...kidney transplantation in early age has been the only way to save patients suffering from NPHP. With a new mouse model Mathias Treier and his group at embl have shed new light on the molecular mechanisms underlying NPHP opening up novel ways to treat the disease. Our mice show striking similari...

Neural Basis of Anxiety: Newer Insights

...ormal mice show less fear towards such ambiguous cues than to clearly threatening stimuli. A team of researchers led by Cornelius Gross at the embl Mouse Biology Unit now discovered that this response to ambiguous stimuli requires a specific receptor molecule for serotonin, a signal many brain cel...

Molecular Basis of Obesity-Revealing the Unknown Facts

...linked. When we are hungry, our spontaneous activity increases and provides us with the drive to go out and find food. Mathias Treier and his group at embl have now discovered the molecule that brings about this link between locomotor activity and food intake in mice. "The molecule is called Bsx a...

Now Fight Iron Disorders With a Drug Against Hypertension

...ollaborators from the University of Heidelberg and embl now found out that nifedipine, a substance commonl...nces its excretion into the urine," says Weiss, an embl alumnus who now heads a lab at the Department for ...e used on patients," says Martina Muckenthaler, an embl alumna who is now at the University of Heidelberg....

LipB Protein Inhibitors Help To Fight Against TB

...ed resistance to drugs. The study results are published in the Proceedings of the National Academy of Sciences (PNAS). Matthias Wilmanns, Head of embl Hamburg reveals the dangerousness and persistence of the bacteria M. tuberculosis. The functions of tuberculosis proteins and their atomic structures...
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(Date:7/24/2014)... A multi-institutional team of researchers has developed a new ... safe, noninvasive method for assessing the function and properties ... to better diagnosis and treatment of gut diseases. ... irritable bowel syndrome and inflammatory bowel disease all occur ... effects in patients with diseases such as diabetes and ...
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