DNA in Medical News

Scientists Track Impact of DNA Damage in the Developing Brain

St. Jude technique yields clues about brain cells targeted by faulty single-strand DNA repair and offers new hints about the roots of neurological disease MEMPHIS, Tenn., July 27 /PRNewswire-USNewswire/ -- Switching off a key DNA repair system in the developing nervous system is...

MO BIO Laboratories, Inc. Launches PowerFood(TM) Microbial DNA Isolation Kit

CARLSBAD, Calif., July 16 /PRNewswire/ -- MO BIO Laboratories, Inc., the leader in soil and microbial nucleic acid purification, announces the launch of an innovative new product, PowerFood(TM) Microbial DNA Isolation Kit, designed to isolate high-quality genomic DNA from food cultured...

ZyGEM Releases Data Confirming Its prepGEM(R) Bacteria Kit Is a Simple, Universal Method for Extracting DNA from Different Bacteria Species

SOLANA BEACH, Calif. and HAMILTON, New Zealand, July 9 /PRNewswire/ -- ZyGEM Corp. Ltd., a provider of innovative enzyme-based products for DNA extraction and other life sciences applications, today announced the availability of a new application note documenting that its prep GEM(R) Bacteria DNA...

Daily sex helps to reduce sperm DNA damage and improve fertility

Amsterdam, The Netherlands: Daily sex (or ejaculating daily) for seven days improves men's sperm quality by reducing the amount of DNA damage, according to an Australian study presented today (Tuesday) to the 25th annual meeting of the European Society of Human Reproduction and Embryology in Amste...

BRIT1 allows DNA repair teams access to damaged sites

HOUSTON - Like a mechanic popping the hood of a car to get at a faulty engine, a tumor-suppressing protein allows cellular repair mechanisms to pounce on damaged DNA by overcoming a barrier to DNA access. Reporting online at Nature Cell Biology this week, a research team led by scientists at ...

USC researchers identify DNA mutation that occurs at beginning point of T-cell lymphoma

Researchers at the Keck School of Medicine of the University of Southern California (USC) have identified a key mechanism that causes chromosomes within blood cells to breakan occurrence that marks the first step in the development of human lymphoma. The study provides researchers with the clea...

Novel DNA vaccine leads to kidney damage prevention in systemic lupus erythematosus models

Copenhagen, Denmark, Thursday 11 June 2009: DNA vaccination using lupus autoantigens and interleukin-10 (IL-10, a cytokine that plays an important role in regulating the immune system) has potential as a novel therapy to induce antigen specific tolerance and may help to prevent kidney damage in pa...

New antibiotics could come from a DNA binding compound that kills bacteria in 2 minutes

A synthetic DNA binding compound has proved surprisingly effective at binding to the DNA of bacteria and killing all the bacteria it touched within two minutes. The DNA binding properties of the compound were first discovered in the Department of Chemistry at the University of Warwick by Professor...

Improved DNA stool test could detect digestive cancers in multiple organs

ROCHESTER, Minn. -- Mayo Clinic researchers have demonstrated that a noninvasive screening test can detect not only colorectal cancer but also the common cancers above the colon -- including pancreas, stomach, biliary and esophageal cancers. This is one of more than 100 Mayo Clinic studies being p...

RevGenetics Releases Its New Science-Based Telomere Health Supplement Formulation for DNA and Chromosome Health

Astral Fruit, a new health supplements product, helps slow and repair some of the natural telomere DNA shortening that happens as we age MIAMI, May 18 /PRNewswire/ -- RevGenetics announces the update and release of its latest science-based telomere health supplements , Astral Fruit. To...

Stopgap DNA repair needs a second step

One can have a dream, two can make that dream so real, goes a popular song. Now a Weizmann Institute study has revealed that it takes two to perform an essential form of DNA repair. Prof. Zvi Livneh of the Weizmann Institute's Biological Chemistry Department has been studying DNA repair for som...

World's largest DNA scan for autism uncovers new gene variant for disorder

UCLA scientists, in partnership with 30 research institutions across the country, have identified a new gene variant that is highly common in autistic children. And when researchers scrutinized the activity of the gene, known as CDH10, in the fetal brain, they discovered that it is most active in ...

ASHG hosts fourth annual DNA Day essay contest, supports genetics education efforts

BETHESDA, MD April 24, 2009 In celebration of National DNA Day, the American Society of Human Genetics (ASHG) and the Genetics Society of America (GSA) have joined with corporate sponsor Life Technologies Corporation (NASDAQ:LIFE) through its Life Technologies Foundation, to educate students and...

Upside-down world: DNA protecting protein helps cancer drug to kill cells

Some DNA repair enzymes can become double-edged swords If they work too slowly, they can block necessary cell maintenance and contribute to cell death. This could explain the somewhat mysterious success of the widely used cancer drug 5-Fluorouracil (5FU) and help clinicians to predict patient's r...

K-State engineers create DNA sensors that could identify cancer using material only one atom thick

Kansas State University engineers think the possibilities are deep for a very thin material. Vikas Berry, assistant professor of chemical engineering, is leading research combining biological materials with graphene, a recently developed carbon material that is only a single atom thick. "The...

Covaris Introduces DNA Shearing Service

WOBURN, Mass., April 2 /PRNewswire/ -- Covaris Incorporated today announced the introduction of DNA shearing service using Covaris instruments and technology. Over the past few years, Covaris instruments have become the gold standard for DNA shearing application, as a sample preparation step ...

Microfluidic Systems (MFSI) is Granted a Microfluidic Cartridge Patent for DNA Separation

FREMONT, Calif., March 30 /PRNewswire/ -- Microfluidic Systems, a privately-held company, announced today that they were granted US patent number 7,491,527 for an automated microfluidic DNA separation cartridge. This microfluidic cartridge technology was developed specifically to automate the sepa...

Genetic changes outside nuclear DNA suspected to trigger more than half of all cancers

A buildup of chemical bonds on certain cancer-promoting genes, a process known as hypermethylation, is widely known to render cells cancerous by disrupting biological brakes on runaway growth. Now, Johns Hopkins scientists say the reverse process demethylation which wipes off those chemical bon...

Penn researchers identify new protein important in breast cancer gene's role in DNA repair

PHILADELPHIA -- For years, researchers have known that under normal conditions, the breast cancer protein BRCA1 orchestrates the repair of damaged DNA, but the details of just how BRCA1 moves to the damaged site and recruits the right nuclear repairmen for DNA restoration remains a mystery. No...

Researchers develop DNA 'patch' for canine form of muscular dystrophy

Using a novel genetic technology that covers up genetic errors, researchers funded in part by the National Institutes of Health have developed a successful treatment for dogs with the canine version of Duchenne muscular dystrophy, a paralyzing, and ultimately fatal, muscle disease. The technolo...

Important new model shows how proteins find the right DNA sequences

Researchers at Uppsala University and Harvard University have collaboratively developed a new theoretical model to explain how proteins can rapidly find specific DNA sequences, even though there are many obstacles in the way on the chromosomes. The findings are being published today in the scient...

New DNA Test Is Basis for Groundbreaking IVF Refund Plan, Easing Financial Burden for Patients

NEW YORK, March 5 /PRNewswire/ -- The Sher Institutes of Reproductive Medicine (SIRM) announced today the introduction of the world's first CGH-Risk Sharing Plan that guarantees qualified IVF patients a baby or offers a full refund of the clinic's medical fees. CGH is an acronym for Compara...

Variations in Gene DNA Boost Drinkers' Cancer Risk

Changes to 2 alcohol-metabolizing enzymes are responsible, study says FRIDAY, Jan. 30 (HealthDay News) -- Variations in the DNA of certain genes can increase the risk of cancer in people who drink alcohol, according to researchers who reviewed studies on alcohol consumption, genetic po...

HPV18 DNA levels are not prognostic for precancerous cervical lesions

Perhaps surprisingly, the number of copies of the carcinogenic human papillomavirus type 18 (HPV18) relative to cellular DNA is not associated with the likelihood of progression to advanced precancerous lesions of the cervix, according to a study in the January 27 online issue of the Journal of t...

Rubicon Genomics Announces a Licensing Agreement With Abbott to Develop and Commercialize DNA Methylation Cancer Tests

ANN ARBOR, Mich., Jan. 12 /PRNewswire/ -- Rubicon Genomics today announced a licensing agreement with Abbott, which marks the achievement of significant milestones within their on-going Research and Option Agreement for development and commercialization of Rubicon MethylPlex(TM) methylation detect...

Burnham researchers illuminate mechanisms that regulate DNA damage control and replication

LA JOLLA, Calif., January 5, 2008Scientists at Burnham Institute for Medical Research (Burnham) have demonstrated important new roles for the protein kinase complex Cdc7/Dbf4 or Cdc7/Drf1 (Ddk) in monitoring damage control during DNA replication and reinitiating replication following DNA repair. S...

Few DNA repair genes maintain association with cancer in field synopsis

Variants of numerous DNA repair genes initially appeared to be statistically significantly associated with cancer risk in epidemiological studies. When the data from individual studies are pooled, however, few DNA repair gene variants appear truly associated with increased cancer risk, according t...

Work with fungus uncovering keys to DNA methylation

Researchers in a University of Oregon lab have shed more light on the mechanism that regulates DNA methylation, a fundamental biological process in which a methyl group is attached to DNA, the genetic material in cells of living organisms. DNA methylation is essential for normal growth and dev...

Transgenomic Obtains Exclusive License to Mitochondrial DNA Damage Detection Technology

OMAHA, Neb., Dec. 4 /PRNewswire-FirstCall/ -- Transgenomic (OTC Bulletin Board: TBIO) today announced that the Clayton Foundation for Research of Houston, Texas through its technology transfer entity, the Research Development Foundation, has granted the Company an exclusive license to patents cove...

Hepatitis C Therapeutic DNA Vaccine Delivered by Inovio Biomedical's Electroporation Technology Reduces Viral Load by Up to 99.7% : Clinical Data Presented at Annual Scientific Meeting of the American Association for the Study of Liver Diseases

Inovio Biomedical Corporation (AMEX:INO), a leader in enabling the development of DNA vaccines using electroporation-based DNA delivery, announced today that its partner, Tripep AB, reported positive additional interim results from its ongoing phase I/II clinical study of its therapeutic DNA vacc...

Does HBV infection induce acute cellular DNA damage?

Eukaryotic cells employ multiple strategies of checkpoint signaling and DNA repair mechanisms to monitor and repair damaged DNA. There are two branches of the checkpoint response pathway, ataxia telangiectasia-mutated (ATM) pathway and ATM-Rad3-related (ATR) pathway. Virus replication presents the...

NIH awards Rutgers Cell and DNA Repository $57.8M

NEW BRUNSWICK, N.J. The Rutgers University Cell and DNA Repository (RUCDR) has received two major awards worth more than $57.8 million from the National Institutes of Health (NIH). One will fund genetic studies of mental disorders and the other will support investigations into the causes of diges...

White blood cell uses DNA 'catapult' to fight infection

SALT LAKE CITY U.S. and Swiss scientists have made a breakthrough in understanding how a type of white blood cell called the eosinophil may help the body to fight bacterial infections in the digestive tract, according to research published online this week in Nature Medicine. Hans-Uwe Simon...

Therapeutic DNA Vaccine Company Inovio Biomedical Reports Second Quarter 2008 Financial Results

Inovio Biomedical Corporation (AMEX: INO) (“Inovio”) today reported financial results for the three and six months ended June 30, 2008. SAN DIEGO (Business Wire EON) August 7, 2008 -- Total revenue for the three and six months ended June 30, 2008 was $663,...

Tufts researchers discover link between DNA palindromes and disease

MEDFORD/SOMERVILLE, Mass. - In the past 10 years, researchers in genome stability have observed that many kinds of cancers are associated with areas where human chromosomes break. More recently, scientists have discovered that slow or altered replication causes chromosomal breaking. But why does ...

Vical to Present Phase 1 Data for Vaxfectin(R)-Formulated Pandemic Influenza DNA Vaccines

SAN DIEGO, July 14 /PRNewswire-FirstCall/ -- Vical Incorporated (Nasdaq: VICL ) today announced the scheduled presentation of preliminary human safety and immunogenicity data from a Phase 1 trial of the company's Vaxfectin(R)-formulated H5N1 pandemic influenza DNA vaccines on Thursday, July 1...

Penn animal study identifies new DNA weapon against avian flu

PHILADELPHIA - Researchers at the University of Pennsylvania School of Medicine have identified a potential new way to vaccinate against avian flu. By delivering vaccine via DNA constructed to build antigens against flu, along with a minute electric pulse, researchers have immunized experimental a...

Faulty DNA repair could be a risk factor for lung cancer in nonsmokers

PHILADELPHIA People who have never smoked but whose cells cannot efficiently repair environmental insults to DNA are at higher risk of developing lung cancer than those with effective genomic repair capability, according to researchers from the Department of Epidemiology at The University of Texa...

Novel DNA microarray chip predicts functional impairment and remission in rheumatoid arthritis

Paris, France, Friday 13 June 2008: A new DNA microarray chip can predict severe disability and remission in patients with rheumatoid arthritis (RA), as presented today at EULAR 2008, the Annual Congress of the European League Against Rheumatism in Paris, France. The chip (called the 'ARTchip') ha...

Whatman, Now Part of GE Healthcare, to Distribute GenVault DNA Recovery Kits in North America

CARLSBAD, Calif., May 29 /PRNewswire/ -- GenVault Corporation, the leader in dry-state, room temperature biosample management solutions announced on May 29, 2008 that Whatman, Now part of GE Healthcare, will become a non-exclusive distributor of GenVault's GenSolve DNA recovery kits in North A...