Novel light-sensitive compounds show promise for cancer therapy

SANTA CRUZ, CA--Chemists at the University of California, Santa Cruz, have developed novel compounds that show promise for photodynamic cancer therapy, which uses light-activated drugs to kill tumor cells. The new compounds, called dye-sensitized ruthenium nitrosyls, are absorbed by cancer cel...

Neuromed Announces that Merck & Co., Inc. Terminates Research Collaboration and License Agreement for Compounds Targeting N-Type Calcium Channels

CONSHOHOCKEN, PA and VANCOUVER, BC, June 11 /PRNewswire/ - Neuromed Pharmaceuticals Ltd. announced today that it has received notification that Merck & Co., Inc. will terminate the research collaboration and license agreement for novel compounds targeting N-type calcium channels for the treatm...

Research Findings on Nine GlaxoSmithKline Cancer Compounds to be Presented at ASCO 2009

Data Include First Presentation of Phase III Progression Free Survival Results for Pazopanib in Kidney Cancer LONDON and PHILADELPHIA, May 11 /PRNewswire/ -- GlaxoSmithKline (GSK) Oncology announced that new clinical data from nine of its oncology molecules will be featured in various pre...

Newly Identified Compounds May Inhibit Strep Infection

Discovery shows promise for reducing bacterial growth FRIDAY, May 1 (HealthDay News) -- Six compounds that may help fight strep infections have been identified by U.S. researchers. Antibiotic resistance is becoming more common among infection-causing bacteria, researchers have warne...

PRA SPEAKING EVENT: Phase I Studies with Hepatitis C Compounds in Healthy Volunteers and Patients: Views from Inside

RALEIGH, N.C., April 8 /PRNewswire/ -- PRA International, a leading Clinical Research Organization, announces Dr. Andre van Vliet, Vice President of Medical Affairs - Early Development Services (EDS), will host an audio conference on the development of New Chemical Entities (NCEs) in the treatment...

Stunning finding: Compounds protect against cerebral palsy

Two compounds developed by Northwestern University chemists have been shown to be effective in pre-clinical trials in protecting against cerebral palsy, a condition caused by neurodegeneration that affects body movement and muscle coordination. "The results were just stunning, absolutely amazin...

AstraZeneca Licenses Novel Antidepressant Compounds Discovered by Mayo Clinic and Virginia Tech Collaboration

Agreement includes research collaboration to generate follow-up TRI compounds WILMINGTON, Del., Feb. 9 /PRNewswire-FirstCall/ -- AstraZeneca, Mayo Clinic, and Virginia Tech Intellectual Properties Inc. today announced that AstraZeneca has licensed a portfolio of preclinical Triple Reuptake In...

New platinum-phosphate compounds kill ovarian cancer cells

ATHENS, Ohio (Nov. 19, 2008) A new class of compounds called phosphaplatins can effectively kill ovarian, testicular, head and neck cancer cells with potentially less toxicity than conventional drugs, according to a new study published this week in the journal Proceedings of the National Academy...

Scientists exploring new compounds to target muscular dystrophy

Scientists have identified a promising set of new compounds in the fight against muscular dystrophy. Using a drug-discovery technique in which molecules compete against each other for access to the target the strand of toxic RNA that causes the most common form of muscular dystrophy in adults ...

University of Illinois - Chicago Study: Raisins Contain Compounds that May Inhibit Cavity-causing Bacteria

CHICAGO, Oct. 27 /PRNewswire/ -- New research published in the journal, Phytochemistry Letters, reveals raisins may benefit oral health because the fruit possesses antimicrobial phytochemicals that suppress growth of some oral bacteria associated with dental cavities and gum disease. The study...

Study Finds Spice-Rich Marinades Can Reduce Harmful Compounds When Grilling

Flavorful Marinades Offer Easy Ways to Enjoy Antioxidant Benefits of Spices and Herbs HUNT VALLEY, Md., July 30 /PRNewswire/ -- Marinating that steak before tossing it on the grill may offer a whole lot more than just increased flavor. Antioxidant-rich spice and her...

Drugs With Marijuana Compounds Don't Boost Adverse Events

But Canadian study finds increase in non-serious side effects FRIDAY June 27 (HealthDay News) -- Drugs that contain compounds called cannabinoids from the marijuana plant don't increase the risk of serious side effects but are associated with an increase in some non-serious side effect...

UCR chemists use 'green chemistry' to produce amines, chemical compounds used widely in industry

RIVERSIDE, Calif. Chemists at UC Riverside have discovered an inexpensive, clean and quick way to prepare amines nitrogen-containing organic compounds derived from ammonia that have wide industrial applications such as solvents, additives, anti-foam agents, corrosion inhibitors, detergents, dyes...

Telik Announces Patents on Compounds Related to TELINTRA

PALO ALTO, Calif., June 10 /PRNewswire-FirstCall/ -- Telik, Inc. (Nasdaq: TELK ), announced today that the European Patent Office has issued notices of allowance for two applications covering new compounds related to one of Telik's lead clinical candidates, TELINTRA(R). Corresponding applicat...

Aspirin-like compounds increase insulin secretion in otherwise healthy obese people

Aspirin-like compounds (salicylates) can claim another health benefit: increasing the amount of insulin produced by otherwise healthy obese people. Obesity is associated with insulin resistance, the first step toward type 2 diabetes. Aspirin and other salicylates are known to reduce blood gluc...

AWWA Urges Science-Based Approach in Addressing Pharmaceutical Compounds in Water

Expert from Southern Nevada Water Authority testifies before Senate subcommittee WASHINGTON, April 15 /PRNewswire-USNewswire/ -- To responsibly address the issue of pharmaceutical compounds in drinking water, scientists must know at what concentration these substances impact human health, ...

Drosophila drug screen for fragile X syndrome finds promising compounds and potential drug targets

Scientists using a new drug screening method in Drosophila (fruit flies), have identified several drugs and small molecules that reverse the features of fragile X syndrome -- a frequent form of mental retardation and one of the leading known causes of autism. The discovery sets the stage for deve...

Stevens chemists identify compounds to lure nutria, a rat-like pest ravaging Gulf Coast wetlands

HOBOKEN, N.J. A 10-pound rodent pest called nutria ravaging southern wetlands in the US, which has been especially damaging to the marshland ecology in the Mississippi Delta following Hurricanes Rita and Katrina, may have finally met its match thanks to molecular science that includes the work of...

Research discovers new compounds active against tuberculosis and malaria

University of Navarra PhD in chemistry researcher, Esther Vicente, has discovered new compounds active for treating tuberculosis and malaria. Her thesis, defended at the Faculty of Sciences in her home city of Pamplona, the capital of Navarre, describes the synthesis and characterisation of 65 der...

Active compounds found in Ganoderma lucidum fungus with potential to treat prostate cancer

A new development in the fight against cancer: Recent research at the University of Haifa found that molecules found in common fungus Ganoderma lucidum aid in suppressing some of the mechanisms involved in the progression of prostate cancer. The main action of the fungus: disrupting androgen recep...

Novel Compounds May Battle Diseases of Aging

Rodent trials suggest they could protect against type 2 diabetes WEDNESDAY, Nov. 28 (HealthDay News) -- Experimental compounds aimed at treating diseases such as type 2 diabetes show promise, scientists say. These "novel chemical entities" activate SIRT1, a gene controlling the aging process,...

Organon Signs an Exclusive, Worldwide Licence Agreement on Advanced Antithrombotic Compounds With Endotis Pharma

OSS, The Netherlands, October 30 /PRNewswire/ -- Organon, the human healthcare business unit of Akzo Nobel, today announced that it has signed an exclusive, worldwide license agreement with Endotis Pharma concerning the development and commercialization of several antithrombotic compounds. End...

VioQuest to Present Data on Oncology Compounds VQD-002 and Lenocta(TM) at AACR-NCI-EORTC International Meeting

BASKING RIDGE, N.J., Oct. 19 /PRNewswire-FirstCall/ -- VioQuest Pharmaceuticals (OTC Bulletin Board: VQPH), a New Jersey-based biopharmaceutical company focused on acquiring, developing and commercializing targeted cancer therapeutics, announced today that it will be presenting data in poster ...

Oxford Performance Materials Introduces OXPEKK Colored Compounds

Colors available in industrial and medical compounds Enfield, CT (PRWEB) March 30, 2009 -- Oxford Performance Materials (OPM) has introduced a line of colored compounds. These new compounds are available in the firm's industrial and medical OXPEKK® products. These n...

InNexus Biotechnology Announces Third Antibody and Expands Pipeline of Anticancer Compounds

BRITISH COLUMBIA, Canada, Aug. 6 /PRNewswire-FirstCall/ -- InNexus Biotechnology Inc., (TSX VENTURE: IXS.V; OTC Bulletin Board: IXSBF) ( http://www.ixsbio.com ), a drug development company commercializing the next generation of monoclonal antibodies based on its Dynamic Cross Linking (DXL(TM))...

ChromaDex Licenses Green Chemistry Technology to Manufacture a New Class of Super Fruit Compounds

Anthocyanins, leucoanthocyanidins and anthocyanidins are natural, plant-based colorants with strong antioxidant properties IRVINE, Calif., July 21 /PRNewswire-FirstCall/ -- ChromaDex Corp., (OTC Bulletin Board: CDXC) a leader in phytochemical reference standards and contract research...

The good and bad side of anti-cancer compounds

Compounds known as HDAC inhibitors exhibit cancer-killing activities in cultured cells. While they are currently being tested as anti-cancer agents in clinical trials, just how they execute their effects is unclear. In a pair of recent papers, Vanderbilt-Ingram Cancer Center investigators prov...

WRAIR investigators pioneering work on an exciting new class of antimalarial compounds

March 26, 2008 Silver Spring, MD: Artemisinins in Malaria Therapy, written by WRAIR researchers Dr. Qugui Li, Dr. Wilbur K. Milhous, and Dr. (COL) Peter J. Weina (Division of Experimental Therapeutics at the WRAIR, Silver Spring, MD) provides a fascinating overview of the historical use and recent...

Lixte Biotechnology Holdings, Inc. Announces Further Developments Regarding the Anti-Cancer Activity of Its Patent-Pending Proprietary Compounds

EAST SETAUKET, N.Y., Feb. 26 /PRNewswire-FirstCall/ -- Lixte Biotechnology Holdings, Inc. (OTC Bulletin Board: LIXT:OB) and its collaborator, the Surgical Neurology Branch (SNB), National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH), reported at t...

Researcher of the University of Navarra discovered potential antidepressant compounds

This release is also available in Spanish . Luis Berrade, a researcher with the Drug R&D Unit of the University of Navarra, has discovered new compounds with the potential for anti-depressant activity. All told, the chemist of the School of Sciences synthesized 51 compounds whose biologic...

Bionovo Describes a New Class of Therapeutic Compounds

- Highly selective estrogen receptor beta agonists have promise for safer therapies in women's health - EMERYVILLE, Calif., Nov. 29 /PRNewswire-FirstCall/ -- Bionovo, Inc. (Nasdaq: BNVI ) announced today the publication of a groundbreaking paper in the journal Molecular and...

Pharmacopeia and GlaxoSmithKline Collaboration Identifies Two Additional Lead Compounds

Lead Selections Trigger Milestone Payments Totaling $1 Million to Pharmacopeia PRINCETON, N.J., Nov. 27 /PRNewswire-FirstCall/ -- Pharmacopeia (Nasdaq: PCOP ), an innovator in the discovery and development of novel small molecule therapeutics, announced today t...

List of Compounds That Causes Breast Cancer Identified

In a recent survey, scientists have identified 216 compounds in our environment that may cause breast cancer . The most inclusive survey till date of environmental chemicals linked to breast cancer has listed 216 compounds, many of which are frequently experienced by most women. The...

New Device Against Harmful Compounds in Air

An Indian researcher and fellow scientists in Japan have developed a new system that can effectively remove some harmful compounds from air that lead to smog// and high ozone levels. Many volatile organic compounds (VOCs) in air, including nitrogen oxides and sulfur oxides, contribute to smog a...

Breakthrough In The Identity Of Compounds That Encourage Stem Cell Growth

Scientists at Harvard University have identified key compounds that stimulate stem cell growth in the brain. // The researchers whose findings, is set to appear in the September 2006 issue of The FASEB Journal hope that this discovery might one day lead to restored function for people who are af...

Two Chemical Compounds Restore Healthy Glucose Levels In Obese Mice

Chemical compounds called PBA and TUDCA were found to restore healthy glucose levels and normal insulin action in obese and diabetic mice, according to new research.// The study is published in the August 25 issue of Science and was conducted by researchers from the Harvard School of Public Health ...

CLA Compounds Fight Diabetes

Components called conjugated linoleic acids (CLA) present in dairy products help diabetes in mice, according to a Penn researcher.// These fatty acids have shown good results in trials and could make way for treating the condition without the need for synthetic drugs. "The compounds are predo...

New compounds Help Sustain relief For Patients With Symptoms of Bowel Disorders

In the latest studies that was presented yesterday at Digestive Disease Week? 2006 (DDW) are finding that long-term therapy with new compounds can sustain relief for these patients with symptoms ranging// from constipation to inflammation. These studies are conducted to review the therapeutic benef...

Beans Devoid Of Flatulence Causing Compounds Would Soon Hit The Market

Researchers from the Simon Bolivar University in Caracas found that Lactobacillus casei (L casei), when fermented along with the beans reduced its flatulence capacity// and increased the nutritional value. Beans are a cheap and key source of nutrition especially in the developing countries. Mar...

Five New Anti-Inflammatory Compounds Produced By Indian Scientists

Five new anti-inflammatory compounds (fight against inflammation) that are 10, 000 times more potent than the most commonly used drugs such as nimusulide and aspirin have been developed and patented by Indian researchers.// Researchers from the All India Institute of Medical Sciences (AIIMS), situa...