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Consensus on "Combination Therapy" for Breast Cancer

Breast cancer is the commonest cancer among women in the world. There has been some on going controversy on certain aspects of treatment modalities of this cancer. Besides surgery there are other options to treat the cancer including radiation, chemotherapy and hormonal therapy. Now at a three-day conference at the National Institutes of Health doctors have agreed to a consensus on the c...

The bad combination

People who drink and smoke have to drink more to feel drunk than non-smoking drinkers – placing them at greater risk of damage to their brains, livers and hearts, a new study suggests. The study shows nicotine substantially reduces blood alcohol levels in rats, which are considered a good model for humans.Since alcohol abusers generally "drink to effect", they will end up drinking mor...

Drug Combinations May Boost Stroke Risk

People who combine different types of serotonin-enhancing medications, such as certain antidepressants and migraine medications, may be increasing their risk of stroke. //The study reports on three patients who developed ischemic strokes related to the use of serotonin-enhancing medications, which include certain antidepressants, anti-migraine drugs, decongestants and diet pills. Ischemic...

Combination therapy to treat breast cancer

The combination of two targeted drug therapies results in dramatic reduction in breast cancer cell growth in vitro, indicating a potentially powerful new approach to treating the condition.// The two drug agents – trastuzumab and ZD1839 were found to work synergistically to inhibit the action of two different growth factors receptors, HER2 and epidermal growth factor receptor (EGFR). P...

Combined scan gives exact cancer diagnosis

A new device makes detection more easier. A combined scanner detects more lesions in cervical and ovarian cancer than the conventional method. It is notoriously difficult to get an accurate picture of ovarian and cervical tumours,// because the tissue is dense and so it's not always possible to detect the border between malignant and normal areas. Doctors at the University of Texas now sa...

Diet combined to Alzheimer's disease

Researchers at the Colulmbia University found that eating more calories and fats may increase the risk of developing Alzheimer's disease in some people. Previous research has shown that mice and rats on a restricted diet tend to live longer. //Researchers feel this is because of fewer destructive molecules formed during the breakdown of food and oxygen. These destructive molecules, known...

Air pollution combined with greater medical needs

Cities with the worst pollution in the US have more hospital admissions for respiratory conditions. There's increasing proof for a tie between environmental pollution and public health. Now doctors at the University of California report upon the effect// of air pollution on Medicare costs in a large group of the population. They looked at medical records and pollution measures in 185...

Combination regime may work against prostate cancer

A recent study published in the Journal of Clinical Oncology suggests that men with advanced Prostate Cancer respond better to a combination of Vitamin D with the chemotherapy drug// Taxotere. A phase II clinical trial of 35 men treated with a combination of Taxotere and Calcitriol found that this combination regime was more effective than treatment with Taxotere alone. This was measur...

Smoking and Breast Cancer - A Deadly Combination

A new study shows women who smoke while undergoing therapy for breast cancer are more than twice as likely to die than non-smokers or those who quit smoking.// Researchers studied more than 1,000 non-smokers and more than 850 smokers who underwent therapy for breast cancer between 1970 and 2002. The study was the first of its kind to examine the effect of long-term smoking on breast canc...

New Drug Combination Found To Improve Memory in Alzheimer’s Patient

New research shows combining the drugs memantine and donepezil may improve // memory in patients with Alzheimer’s disease. Researchers studied more than 300 patients with moderate to severe Alzheimer’s. Participants were already taking the drug donepezil when the study began. Donepezil works by preventing the breakdown of acetylcholine, a chemical messenger in the brain that is important...

A Combination Of Drugs Effective In The Treatment Of Hormone-Refractory Prostate Cancer

A recent study has shown that a chemotherapy regimen combining vinorelbine (Navelbine) and mitoxantrone (Novantrone)// with the corticosteroid prednisone is effective in the treatment of hormone-refractory prostate cancer . Specialists say this treatment should be offered to symptomatic patients earlier in their disease. However researchers added that a larger phase 2 study of this tre...

Combination Therapy Effective In Improving Lung Cancer Survival

Researchers from Japan say that the combination of chemotherapy with a new medication could improve survival among lung cancer patients.// In the study of close to 1,000 patients, the overall survival rate was significantly higher in patients who received chemotherapy and the oral drug uracil-tegafur. Results of the study show 65 patients who received the combined therapy died within...

Combination Therapy Found To Improves Stroke Recovery

Stroke patients treated with ultrasound therapy in addition to medication show an improved clinical recovery // compared to patients only treated with medication, according to a new study. Researchers examined 126 patients who suffered acute ischemic stroke due to a blockage in the middle cerebral artery. All the patients were treated with tissue plasminogen activator (t-PA) within three...

Combination Therapy Found To Be More Effective In Treating Brain Cancer

Researchers say adults suffering from the most common form of brain cancer might fare better with a combination of radiotherapy and // chemotherapy than radiotherapy alone . Based on findings of the study it was seen that most people with the type of cancer known as glioblastoma receive surgery to remove as much of the cancer as safely possible and then undergo radiotherapy. The current...

Combination of Clopidogrel-aspirin is better for preventing stroke than only aspirin

In reducing blood clots, the combination of Clopidogrel and aspirin is more effective than only aspirin//. The results were declared after 107 participants across four countries of the Europe were given the combination medication or only aspirin. Each of the participants of the study had had a stroke or transient ischemic attack (TIA). All the patients have at least 50% narrower caro...

Warding off symptoms of premenstrual syndrome by combination therapy

Based on findings of a recent study researchers say that a diet rich in calcium and Vitamin D //abundantly available in milk, cheese, yogurt and fortified orange juice can actually help women reduce the risk of Pre - Menstrual Syndrome (PMS) symptoms. Studies in the past have shown that calcium has helped women cope with PMS, however more recent studies suggest that when calcium is combi...

New Combination Therapy Option for HIV Patients

A HIV protease inhibitor Aptivus ( tipranavir ) , has been recently approved by the Food and Drug Administration // . The capsules are to be given in combination with ritonavir for treatment of HIV-1 infected adults. This is the second drug approved for patients with advanced HIV disease, and provides a new therapy for patients with limited treatment options. The benefits of Aptivus i...

Cholesterol can be lowered using combination of Soy Proteins and Sterols

Heart disease is responsible for nearly half (49 per cent) of all deaths //in Europe, killing more than 4.35 million people each year. Reducing cholesterol is one of the most important preventable factors in the disease. Both soy protein and plant sterols extracted from soy are already well established in the heart health foods market, with the US Food and Drug Administration backing he...

Combing Hair More Effective Than OTC Medicine For Head Lice

Researchers have shown that fine combing of wet hair may be far more effective treatment of head //lice than over-the-counter (OTC) treatment. Researchers have used single blind randomized controlled trial for comparing the Bug Buster kit with over the counter insecticide treatments against head lice in United Kingdom. Fine combing of wet hair is far more effective than curre...

Malignant virus in polio vaccine combined to Cancer

Researchers have found traces of a monkey virus that contaminated the polio vaccine in the early 50's in a common form of highly malignant human cancer that has mystically doubled in incidence over the past 30 years. Two studies, found a link between the virus, called SV40, and non-Hodgkin lymphomas, a disorder ranked fourth or fifth among cancer deaths in the United States among women a...

New combined therapy for Knee Joint pain

Knee pain is the most common problem among women. However statistics show that among people affected than others. However statistics show that among people affected with knee joint pain, obese people are in the majority. We have to consider many factors before we can be definite about the reasons for the knee pain. //Majority of the people are affected by Osteoarthritis. It is explained b...

Nanocells cancer combination therapy acts as chemotherapy as well as anti-angiogenic drug

Cancer chemotherapy is not effective in treating cancer efficiently due to its non-specificity and inability to target the cancer cells alone. Due to this non-specificity there is increased // development of drug resistance shown by these cancer cells. Normal cells and cancer cells depend on blood supply for sustenance and oxygen. Cutting off blood supply could be one way to kill the ca...

A Protein-Rich Diet Combined With Exercise Found To Be More Effective In Weight Loss

The trial on almost 50 overweight women confirms previous studies showing that a high-protein diet can lead to greater fat loss than a low-calorie, high carbohydrate diet. Researchers have also demonstrated that when both regimes are combined with an exercise programme, the protein-rich diet is still more effective at reducing body fat. // Researchers say there's an added interactive ef...

Calcitriol [Vitamin D] with combination of painkillers for cancer treatment

Professor David Feldman and his colleagues from the Stanford University School of Medicine have reported the results of their study in the journal Cancer Research. The result of the study has found that //high doses of Vitamin D with pain killers were found to reduce the growth of cancer in patients with prostate cancer. The study result say that the combination of these two drugs reduces...

Combined modality approach for effective treatment and enhanced survival in bile duct cancer

Hilar cholangiocarcinoma is a type of bile duct cancer. Conventional therapy for this for of cancer is to remove (resect) the tumor, which may require removing part of the liver. Survival for patients// with this type of operation is only 25 to 35 percent, and many patients cannot be treated this way because the tumors can involve both sides of the liver. Cholangiocarcinoma is a relati...

Combination Therapy To Avoid Prostate Cancer Recurrence

Researchers from National Cancer Institute has tested the efficacy of a new combination therapy of combining cancer vaccines and Anti-androgen hormone therapy to Prostate cancer patients who showed resistance to hormone therapy // but had no metastatic disease. The Phase II trial was conducted in 42 Prostate cancer patients with no metastatic spread but having high Prostate Specific Anti...

Chloroquine and Primaquine combination Malarial drug for resistant parasites.

Researchers from LaTrobe University of Australia have found a new combination drug for combating Plasmodium falciparum, the parasite responsible for causing malaria. They used a combination of Chloroquine and Primaquine for treatment // helps in killing P. falciparum which is resistant to Chloroquine drug. Chloroquine is a largely used drug in the treatment of malaria since 1950s. Chlo...

Eloxatin combination reduces bowel cancer recurrences

Bowel cancer is one of the most common cancers occurring in humans. A clinical study involving patients taking supplementation of Eloxatin drug with other chemotherapeutic cancer drug for treatment of bowel // cancer has found better prognosis and reduced recurrence in these patients. This study which is called as NICE study has proved a combination of Eloxatin with chemotherapeutic drugs...

Tamiflu Shortage Can Be Better Handled By Combining It With Probenecid

Drug Synergism refers to the enhancement in action or effect of a particular drug than the individual effect of both the drugs combined. The phenomenon could be exploited in the present scenario where the avian bird flu is posing a serious threat across different regions of the globe. // Tamiflu is a prescribed drug for seasonal flu, because it will be a first line of defense if the H...

HRT And Alcohol Combine Increases Risk Of Breast Cancer

In what is a huge indictment of the hormone replacement therapy (HRT), Swedish scientists at the Karolinska Institutet say that alcohol is contraindicated in women on HRT since it increases the risk of developing the most // common form of breast cancer in these women. Hormone Replacement Therapy is the option that most women take to after reaching menopause. This method of replacing th...

Death from heart attack can be reduced by new drug combination

Heart attack remains one of the significant causes for mortality in more than 10 million people all over the world. It accounts for 29.2 percent of total global deaths according to the World Health Organization.// People who survive the episode require long-term care and support. Amongst the risk factors, the important ones are obesity, smoking, diabetes, high blood pressure and high chol...

Combination drugs for emergency heart attacks

Professor Zhengmin Chen and his team from Oxford University have found that combining anti-clotting drug Clopidogrel to aspirin to heart attack patients may have more good effect in saving lives compared to single drug medications. //Anti-clotting drugs help in thinning of blood during a heart attack and help in removing clots and do not have any serious side effects of bleeding. Resear...

Vision Loss in Elderly Caused By Combined Effect of Genes and Bacterium

A definitive link has been established between age-related macular degeneration and the genetic mechanisms underlying the disease process. The finding has been confirmed by the identification of a bacterium //called Chlamydia pneumoniae in the diseased tissue of the affected individuals. It is also notable that the microorganism is associated with chronic inflammation and heart disease....

Combination Therapy With ENBREL And Methotrexate Found Effective In RA Treatment

Combination therapy with anti-TNF agents (etanercept) and chemotherapy drug methotrexate has been shown to be effective in the treatment of Rheumatoid Arthritis.// Furthermore, the progression of joint damage has been considerably slowed down in over three quarters of patients. The chronic nature of the severe disabling condition necessitates the need for prevention of long-term joint dam...

New tetanus-diphtheria combination vaccine launched by Serum Institute of India

A combination vaccine for immunization against tetanus and diphtheria, Td-Vac priced at Rs. 7.50 has been launched by Serum Institute of India // . The vaccine is aimed at combating the fatal tetanus and diphtheria (Td) in adolescents and adults. It is much different than the currently existing dual antigen vaccine used in children and would be used as an alternative to the TT (Tetanu...

Combination therapy for patients treated with Implantable Cardioverter Defibrillator

Professor Stuart J. Connolly and his team from McMaster University in their clinical trial reported in the journal JAMA that a combination of Antiarrhythmic drugs such as amiodarone combined with beta blockers such as Sotalol // found to reduce the painful shocks in ventricular arrhythmia patients undergoing Implantable Cardioverter defibrillator (ICD). ICD treatment produces high voltage...

New Drug Combination For Fighting Tuberculosis

The Government of Zimbabwe has applied for a financial grant amounting to approximately 110// million U.S. dollars, to develop a new drug for combating tuberculosis, said the Cabinet Minister. // The application has been forwarded to the Global Fund on AIDS, TB and Malaria, according to the Health and Child Welfare Minister. It is anticipated that approximately 15 and 30 million doll...

More effective Antiretroviral HIV drug combination

Professor Joel Gallant and his team from Johns Hopkins University School of Medicine as reported in the Journal The New England Journal of Medicine // that Antiretroviral combination drug of Tenofovir, Emtricitabine and Efavirenz is found to be effective in controlling HIV load compared to most widely used drug combination Zidovudine, Lamivudine and Efavirenz. The clinical trial calle...

Combination growth factors for Stem cell proliferation

Professor Harvey Lodish and his post-doc Chengcheng Zhang from Whitehead Institute for Biomedical Research in Cambridge have found a combination of growth factors// which enriches and increases the number of stem cells in the laboratory before it could be injected into the recipient. Stem cell therapy as shown that the quantity of stem cells required for a therapy is very high and it r...

Combination of Schizophrenia drugs not beneficial

Professor William Honer and researchers have reported the results of the study in New England Journal of Medicine in which they found in a trial conducted in 68 patients over // the benefits of combining two antipsychotic drugs Clozapine and Risperdal for treatment of Schizophrenia. The researchers found that this combination drug did not work positively in controlling the symptoms of S...
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