Carcinoma in Medical News

What is the relationship between hepatocellular carcinoma and type 2 diabetes mellitus?

Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide and the third leading cause of cancer-related deaths. Type 2 diabetes mellitus has been associated with HCC. However, the relationship between type 2 diabetes mellitus and the underlying liver cirrhosis, and the effects o...

The small cell neuroendocrine carcinoma of the ampulla of vater

Ampullary small cell neuroendocrine carcinoma is extremely rare and has only been documented in few case reports and retrospective study. The patients with ampullary small cell neuroendocrine carcinoma usually presented after the age of 60 years, and a male predilection was observed. Only two case...

Recurrent low-grade carcinoma of the ovary less responsive to chemo than more common ovarian cancers

Tampa, Fla.- Recurrent low-grade serous carcinoma, a rare type of ovarian cancer, is less sensitive to chemotherapy and therefore more difficult to treat than more common high-grade ovarian cancers, according to researchers from The University of Texas M. D. Anderson Cancer Center. The findings we...

Al Copeland Day Lives on Through Efforts To Cure Merkel Cell Carcinoma

20th Anniversary of Al Copeland Day Honored with $150K Donation to the University of Pittsburgh Cancer Institute NEW ORLEANS, June 30 /PRNewswire/ -- After losing a battle to Merkel Cell Carcinoma, an aggressive and deadly form of skin cancer, the memory of Al Copeland will be honored t...

A potential drug for liver carcinoma

Looking for efficient anti-tumor drugs is a hot research area. Chrysin (5,7-dihydroxy flavone), a natural widely-distributed flavonoid, has been reported to have many different biological activities such as anti-oxidant, anti-virus, antidiabetogenic activity and clear anxiolytic effect. However, C...

A novel marker of colorectal carcinoma

The colorectal cancer is thought to be resulted from a combination of environmental factors, diet, lifestyle, chronic inflammation and accumulation of specific genetic alterations. The pathogenesis and development of colorectal cancer involve multi-genes and multi-steps. TSPAN1 (GenBank Accession ...

A feasible, simple and convenient model for study of rectal carcinoma

The method of building a rabbit rectal VX2 carcinoma model by injecting the cell suspension of VX2 cells into the wall of the rectum guided by X-ray fluoroscopy is feasible. The advantages of the model are ease of establishment, short growth period, and high stability. The rectal VX2 carcinoma est...

Future for radioembolisation in patients with advanced hepatocellular carcinoma

Copenhagen, Denmark, Friday 24 April: Radioembolisation with Yttrium-90 (Y-90) glass microspheres is a safe and effective treatment for patients with advanced HCC portal vein thrombosis, according to new research presented today at EASL 2009, the Annual Meeting of the European Association for the...

NCCN Presents Updates to NCCN Guidelines for Thyroid Carcinoma

NCCN presented new updates to the NCCN Clinical Practice Guidelines in Oncology(TM) for Thyroid Carcinoma at the NCCN 14th Annual Conference on March 14. Notable updates include a new page on Thyroid Stimulating Hormone (TSH) Suppression, the expanded recommendation of small molecule kinase inhibi...

Molecular Breast Imaging Has Greater Sensitivity Over Mammography, Ultrasound and MRI for Invasive Lobular Carcinoma

CHICAGO, Dec. 2 /PRNewswire/ -- Breast-Specific Gamma Imaging (BSGI) has been proven to be a highly sensitive imaging technique for the diagnosis of invasive lobular carcinoma (ILC), a difficult to diagnose breast cancer. BSGI is a molecular breast imaging technique that can see lesions independen...

A useful imaging modality for monitoring treatment response to hepatocellular carcinoma

TACE has been widely accepted as a choice of treatment for advanced HCC. CT perfusion is a non-invasive and reproducible technique for assessing perfusion changes due to TACE therapy for locally advanced HCC. However, there are few reports on the application of this technique in evaluating the eff...

A potential targets for the prevention or treatment of esophageal carcinoma

Expression of Livin in fresh esophageal cancer tissues was detected by immunohistochemistry (IHC), Western blotting and reverse transcriptase-polymerase chain reaction (RT-PCR), VEGF by Its correlation Western blotting and RT-PCR. Livin positivity was also significantly correlated with tumor stage...

LOH analysis on 4q in sporadic colorectal carcinoma

Thirteen fluorescent labeled polymorphic microsatellite markers were analyzed in 83 cases of colorectal carcinoma and matched normal tissue DNA by polymerase chain reaction (PCR). PCR products were eletrophoresed on an ABI 377 DNA sequencer. Genescan 3.7 and Genotype 3.7 software were used for los...

A new chemotherapeutic target for hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a major health problem worldwide. Currently, the only chance for obtaining a cure in patients with HCC is by either a surgical resection or liver transplantation. However, many HCCs with scattered tumors cannot be operated on. In such patients, effective alternati...

Intra-arterial combination chemotherapy induces long-term survival for hepatocellular carcinoma

Portal venous tumor thrombus (PVTT) is a crucial factor that can worsen the prognosis of patients with hepatocellular carcinoma (HCC). It often leads to extensive spreading of the tumor throughout the liver, and can increase portal venous blood pressure, resulting in the fatal rupture of esophagea...

A Chinese medicine compound has satisfactory anti-cancer effects on hepatocellular carcinoma

Traditional Chinese medicine is world renowned. It has supernatural effects on some diseases, but the reason is still unknown. One such article was recently reported in the November 7 issue of the World Journal of Gastroenterology dealing with the great significance of a Chinese medicinal compound...

New Biotech Drugs to Aid in Renal Cell Carcinoma Treatment

Two biotech drugs produced by Bayer AG, Pfizer and Onyx pharmaceuticals are astounding doctors with their effects on decreasing the progression// of metastatic kidney cancer. The drugs, sunitinib (marketed under brand name Sutent) and sorafenib (brand name Nexavar) have been found to delay t...

Bronchiolo-alveolar Carcinoma Shows Sonographic Pattern Of Pneumonia

Recent research conducted in Germany indicates that bronchiolo–alveolar carcinoma frequently shows a sonographic pattern of ‘pneumonia’//. The acoustic–physical conditions of the thorax produces the most serious limitations for the sonographic diagnosis of pulmonary diseases. ...

Differentiated Thyroid Carcinoma Can Widely Infiltrate The Larynx

The proximity of the thyroid gland to the larynx, trachea, pharynx, and cervical esophagus allows thyroid cancer// to invade these structures. Invasion of the larynx by differentiated thyroid gland carcinoma is uncommon, but causes serious morbidity and mortality when present. A recent article, ...

A Novel Method Of Detection Of High Nuclear Grade Localized Renal Cell Carcinoma

Elective nephron-sparing surgery (NSS) is considered appropriate for small renal cell carcinoma (RCC) tumors; however, it is still difficult to detect high nuclear grade RCC preoperatively. // Although no specific tumor markers have been identified for RCC, immunosuppressive acidic protein (IAP)...

Probable Biomarkers for Squamous Cell Carcinoma

Genetic alterations have been found to be to be associated with the development of skin cancers related to smoking//. These cancers; squamous cell carcinomas(SCC), are seen in the head and neck area. Charis Eng of the Genomic Medicine Institute at the Cleveland Clinic Foundation and colle...

Micromet, Inc. Reports Second Quarter 2009 Financial Results

... (MT201) also binds to EpCAM and is being developed under a collaboration with Merck Serono. Adecatumomab is in a phase 2 clinical trial in colorectal carcinoma patients after complete resection of liver metastases, and a phase 1b clinical trial evaluating adecatumumab in combination with docetaxel for the tre...

Diagnostic tools and innovative therapies improve patient prognosis

... by comparing non-small cell lung cancer (NSCLC) cell lines and examining their production of VOCs. Ten adenocarcinoma (AC) and two squamous cell carcinoma (SCC) cell lines were grown in standard conditions and compared to control. Gas-chromatography mass spectrometry was used to examine the chemical natu...

Virus May Affect Survival in Head and Neck Cancer

...There is currently no consensus on why blacks fare worse with squamous cell carcinoma of the head and neck than whites, but this is the first clue that it may be...n at the University of Texas M.D. Anderson Cancer Center. "Squamous cell carcinoma of the head and neck is one of the fastest- growing cancers, and this study...

HPV Infection May Be Linked to Poor Head and Neck Cancer Survival Rates in African Americans

...lomavirus (HPV) improves survival in squamous cell carcinoma of the head and neck. Furthermore, African America...sensus on why blacks fare worse with squamous cell carcinoma of the head and neck than whites, but this is the ...t;practice changing." "Squamous cell carcinoma of the head and neck is one of the fastest growing...

HPV infection may be linked to poor head and neck cancer survival rates in African-Americans

...lomavirus (HPV) improves survival in squamous cell carcinoma of the head and neck. Furthermore, African America...sensus on why blacks fare worse with squamous cell carcinoma of the head and neck than whites, but this is the ...d the study "practice changing." "Squamous cell carcinoma of the head and neck is one of the fastest growing...

Low prevalence of HPV infection may be tied to poor prognosis for blacks with head and neck cancer

...the study, "practice-changing." "Squamous cell carcinoma of the head and neck is one of the fastest growing...nly 4 percent of black patients with squamous cell carcinoma in the study were HPV-positive, compared with 34 p...sensus on why blacks fare worse with squamous cell carcinoma of the head and neck than whites, but our findings...

QuatRx Announces Further Positive Phase 3 Results For Ophena(TM) (Ospemifene Tablets) in Postmenopausal Vaginal Atrophy

...ds were apparent in severe treatment-emergent adverse events and no cases of pelvic organ prolapse, venous thromboembolism, endometrial hyperplasia or carcinoma were observed. Overall, the results of this double-blind, placebo-controlled, long-term safety extension study demonstrated that daily doses of 60mg ...

Amgen's Second Quarter 2009 Adjusted Earnings Per Share Increased 13 Percent To $1.29

...update on several of its clinical programs: AMG 102: In Phase 2 studies, limited efficacy was seen in glioblastoma multiforme and renal cell carcinoma when AMG 102 was administered in monotherapy, but the effect size was not large enough to warrant moving forward with late-stage studies in these indi...

Smoking increases potential for metastatic pancreatic cancer

...ary & Related Cancers Center. Nicotine promotes the expression osteopontin, and high levels of osteopontin have been reported in pancreatic ductal carcinoma (PDA). Dr. Arafat and her research team analyzed PDA samples and confirmed that the isoform, called OPNc, was also expressed on invasive PDA lesions. ...

Xoft Expands Cancer Treatment Platform With Launch of Skin Cancer Electronic Brachytherapy Trial at AAPM Meeting

... melanoma is the most serious form of skin cancers, it accounts for less than 10 percent of all cases. Non-melanoma skin cancers, such as basal cell carcinoma and squamous cell carcinoma, represent the majority of all new cases. "I am very excited to be the principal investigator for the first clinic...

Nexavar in Combination with Chemotherapy Shown to Extend Progression-Free Survival in Patients with Advanced Breast Cancer

...ns For Patients Taking Nexavar Based on the currently approved U.S. package insert for the treatment of patients with unresectable hepatocellular carcinoma and advanced kidney cancer, hypertension may occur early in the course of therapy and blood pressure should be monitored weekly during the first six w...

Amgen Announces KRAS Safety Update to U.S. Prescribing Information for Vectibix(R) (Panitumumab)

...h epidermal growth factor receptor (EGFr)- expressing metastatic colorectal carcinoma after disease progression on, or following fluoropyrimidine-, oxaliplatin- ... a single agent for the treatment of EGFr-expressing, metastatic colorectal carcinoma is based on progression-free survival. Currently no data demonstrate an imp...

Innovative Prostate Cancer Treatment Known as Sonablate(R) HIFU Now Available at Third Site in India

... Mr. Mukesh Rana, Country Manager, India HIFU "Sonablate HIFU on initial use is very patient friendly for those who are suffering from carcinoma prostate as there is no immediate morbidity which is expected if the patient chooses radical surgery. The long term side effects are also reduced sinc...

Study Evaluating Efficacy and Safety of Two Low-dose Regimens of PREMARIN Vaginal Cream for the Treatment of Moderate to Severe Vaginal Atrophy Now Published

...n women who completed the 52-week study period and had evaluable endometrial biopsies. There were no reports of endometrial hyperplasia or endometrial carcinoma in these women in either regimen. In this study, the most common treatment emergent AE's were headache, infection, arthralgia and vaginitis. ...

JNCI news brief: Hepatitis B virus mutations may predict risk of liver cancer

... a large meta-analysis in the Journal of the National Cancer Institute , published online July 2. HBV infection is a known cause of hepatocellular carcinoma (HCC), the most common form of liver cancer. Previous studies have looked at whether patients with specific mutations in the viral DNA may be at incre...

Positive CHMP Opinion for JAVLOR(R) in Metastatic Treatment of Bladder Cancer After Failure of a Prior Platinum-Containing Regimen

...e treatment of adult patients with advanced or metastatic transitional cell carcinoma of the urothelial tract after failure of a prior platinum-containing regime...e treatment of adult patients with advanced or metastatic transitional cell carcinoma of the urothelial tract after failure of a prior platinum-containing regime...

First Day of Summer Has Come: Enjoy the Summer Sunshine Without Putting Yourself at Risk

...our chance of getting melanoma increases significantly if you've already had a previous melanoma, but also increases if you have had either basal cell carcinoma or squamous cell carcinoma, the more common forms of skin cancer Melanoma appears most frequently on the torso area in fair-skinned men and on...

Phase 1 Study Initiated with Micromet Anti-GM-CS Human Antibody MT203

... (MT201) also binds to EpCAM and is being developed under a collaboration with Merck Serono. Adecatumomab is in a phase 2 clinical trial in colorectal carcinoma patients after complete resection of liver metastases, and a phase 1b clinical trial evaluating adecatumumab in combination with docetaxel for the tre...

Nicotine Receptors Could Be Lung Cancer Treatment Target

...α-CbT), which specifically targeted the area most linked to increased cell growth. In the study, researchers grafted human non-small-cell lung carcinoma (NSCLC) onto the lungs of mice and then delayed treatment, allowing the tumors to become well-established. The mice were then divided into three gr...