Fox Chase researchers identify differences in treatments and outcomes of patients with second primary lung cancers versus those with one primary lung cancer

SAN FRANCISCO (August 1, 2009)Patients with second primary lung cancers (SPLC), when compared to those with one primary lung cancer (OPLC), are more likely to have localized disease at the time of diagnosis and are more likely to receive surgical treatment rather than radiation treatment. However,...

AIDS patients face higher risk of HPV-related cancers as immunosuppression grows

Risk of human papillomavirus (HPV)-associated cancers is greater for people living with AIDS and increases with increasing immunosuppression, according to a new study published online July 31 in the Journal of the National Cancer Institute. Although the risk of HPV-associated cancers is known...

Clinical Studies Validate Cancer Gene Delivery Platform: Landmark Publication Confirms Rexin-G Effectively Targets Metastatic Cancers and Improves Patient Survival

SAN MARINO, Calif., June 22 /PRNewswire/ -- Epeius Biotechnologies ( www.epeiusbiotech.com ) stuns the medical and scientific communities with a dramatic demonstration of single-agent efficacy with its lead product, Rexin-G, for metastatic cancer. The landmark article (accessible online as of Ju...

New Tests Spot Tough-to-Detect Cancers Sooner

Researchers devise method for early confirmation of bile duct, pancreatic cancers,, WEDNESDAY, June 3 (HealthDay News) -- Mayo Clinic researchers say they have developed new tests that make it easier to diagnose cancers of the pancreas and bile ducts. In a study, the new tests more ...

Improved DNA stool test could detect digestive cancers in multiple organs

ROCHESTER, Minn. -- Mayo Clinic researchers have demonstrated that a noninvasive screening test can detect not only colorectal cancer but also the common cancers above the colon -- including pancreas, stomach, biliary and esophageal cancers. This is one of more than 100 Mayo Clinic studies being p...

Breast MRI detects additional 'unsuspected' cancers not seen on mammography or ultrasound

Nearly 20% of patients with recently diagnosed breast cancer had additional malignant tumors found only by MRI, according to a study performed at Dartmouth Hitchcock Medical Center. A total of 199 patients with newly diagnosed breast cancer underwent breast MRI. "We found additional, unsuspect...

Video: Research in Women's Cancers Leading the Personalized Medicine Revolution

TAMPA, Fla., May 6 /PRNewswire/ --- With more than 223,000 American women estimated to be diagnosed with breast or gynecologic cancers in 2008, Moffitt Cancer Center is leading the current movement toward focusing more on personalized cancer care treatment techniques to break new ground with...

Multifocal lung cancers appear to originate from single cancer clone

Multiple, anatomically distinct lung cancer tumors may frequently arise from a single cancer cell, according to a retrospective analysis of patient tumor samples published in the April 7 online issue of the Journal of the National Cancer Institute. Some lung cancer patients have multiple anat...

Ovarian cancers detected early may be less aggressive, questioning effectiveness of screening

DURHAM, N.C. -- The biology of ovarian cancers discovered at an early stage may render them slower growing and less likely to spread than more aggressive cancers, which typically are discovered in an advanced stage, according to a study led by investigators in the Duke Comprehensive Cancer Center....

Early detection of second breast cancers halves women's risk of death

A group of international researchers has found the first reliable evidence that early detection of subsequent breast tumours in women who have already had the disease can halve the women's chances of death from breast cancer. According to the research published online today (Wednesday 18 March)...

Freezing Kidney Cancers Shows Promise

Study found noninvasive technique eradicated smaller tumors FRIDAY, March 13 (HealthDay News) -- Most kidney cancer tumors can be eradicated using a noninvasive freezing technique that eliminates the need for surgery, a pair of studies from Johns Hopkins Hospital suggests. The findi...

Report: Many Cancers Could Be Prevented in US

Comprehensive, Evidence-Based Recommendations for All Levels of Society WASHINGTON, Feb. 26 /PRNewswire-USNewswire/ -- A new global policy report estimates that approximately 45 percent of colon cancer cases and 38 percent of breast cancer cases in the US are preventable through diet, physica...

Landmark Policy Report: Many Cancers Could Be Prevented Across the Globe

Comprehensive, Evidence-Based Recommendations for All Levels of Society WASHINGTON, Feb. 26 /PRNewswire-USNewswire/ - A new global policy report estimates that approximately 37 percent of colon cancer cases and 2 8 percent of breast cancer cases in middle-income countries like Mexico a...

Landmark Report: Many Cancers Could be Prevented

LONDON, February 26 /PRNewswire/ -- Over 40 per cent of colon and breast cancer cases in some countries are preventable through healthy patterns of diet, physical activity and weight maintenance, according to estimates in a report that has set out recommendations for policies and actions to pr...

2 gene mutations linked to most common brain cancers -- and longer survival

Scientists at the Johns Hopkins Kimmel Cancer Center and Duke University Medical Center have linked mutations in two genes, IDH1 and IDH2, to nearly three-quarters of several of the most common types of brain cancers known as gliomas. Among the findings: people with certain tumors that carry thes...

Black women with uterine cancers more likely to die than white patients

Black women with cancers of the uterus are less likely to survive the disease than white women, and relatively little progress has been made over the past two decades to narrow this racial difference. That is the conclusion of a new study published in the March 15, 2009 issue of CANCER , a peer-r...

Better MRI scans of cancers made possible by TU Delft

Researcher Kristina Djanashvili has developed a substance that enables doctors to get better MRI scans of tumours. On Tuesday 13 January, Djanashvili will be awarded a doctorate by TU Delft for her work in this field. The medical profession's ability to trace and visualise tumours is increasing...

Gene plays dual role in breast cancers with poor prognosis

A new study reveals that the metadherin gene (MTDH) plays a role in both cancer metastasis and resistance to chemotherapy. The research, published by Cell Press in the January 6th issue of the journal Cancer Cell , identifies MTDH as a promising therapeutic target for high risk breast cancers. ...

Diet may cut second breast cancers in women without hot flashes

A secondary analysis of a large, multicenter clinical trial has shown that a diet loaded with fruits, vegetables and fiber and somewhat lower in fat compared to standard federal dietary recommendations cuts the risk of recurrence in a subgroup of early-stage breast cancer survivors women who didn...

Some Breast Cancers May Regress on Their Own

Study of women receiving mammography suggests it happens TUESDAY, Nov. 25 (HealthDay News) - Some breast cancers may naturally disappear without treatment, a study of women undergoing mammography suggests. The Norwegian study found that more cases of breast cancer were diagnosed aft...

Mammograms may detect some cancers that would have otherwise regressed

Breast cancer rates increased significantly in four Norwegian counties after women there began undergoing mammography every two years, according to a report in the November 24 issue of Archives of Internal Medicine , one of the JAMA/Archives journals. Rates among regularly screened women remained...

Study finds racial disparities increasing for cancers unrelated to smoking

ATLANTA November 6, 2008A new American Cancer Society study finds that recent progress in closing the gap in overall cancer mortality between African Americans and whites may be due primarily to smoking-related cancers, and that cancer mortality differences related to screening and treatment may s...

U.S. Reported 25,000 Cases of HPV-Related Cancers Annually

Most frequent tumor sites were cervix, head and neck, government study finds MONDAY, Nov. 3 (HealthDay News) -- An estimated 25,000 cases of cancers associated with human papillomavirus (HPV) occurred in 38 states and the District of Columbia between 1998 and 2003, U.S. officials repor...

HPV virus helps cervical and head and neck cancers resist treatment and grow and spread

The human papillomavirus (HPV) allows infected cervical and head and neck cancer cells to maintain internal molecular conditions that make the cancers resistant to therapy and more likely to grow and spread, resulting in a poor prognosis for patients, researchers with UCLA's Jonsson Cancer Center ...

Grupo IMO Hosts Symposium on Use of TomoTherapy for Stereotactic Radiosurgery and Stereotactic Body Radiation Procedures : Experts Detail HiArt Platform Advantages for Treatment of Brain, Lung, Pancreatic and Metastatic Cancers

TomoTherapy Incorporated (NASDAQ: TOMO) announced today that Grupo IMO of Madrid, Spain, recently hosted a symposium on the clinical use of the HiArt treatment system for stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT). Symposium speakers highlighted the HiArt syste...

Study Suggests How Cancers Spread to Lungs

A complex signaling system paves the way for metastasis, researchers say MONDAY, Sept. 29 (HealthDay News) -- Cancers typically spread -- or metastasize -- to specific, predictable locations. Now researchers have a deeper molecular understanding of why, at least for lung metastases in...

Broad Screening of Blood Clots May Find Cancers Earlier

Analysis suggests CT scan could boost detection 21% in those with unexplained masses FRIDAY, Sept. 12 (HealthDay News) -- Doing more thorough screening of people with unexplained blood clots -- particularly in the legs, arms and lungs -- could increase the rate of cancer detection amon...

Gene Activity May Explain Deadlier Breast Cancers Among Younger Women

Study finds more than 350 common sets of genes in patients under 45 WEDNESDAY, July 9 (HealthDay News) -- Genetic activity in breast cancer cells from younger patients could explain why tumors tend to more aggressive when they strike at a younger age. "We haven't had a good reason w...

Future hope for patients with breast cancers resistant to tamoxifen

Researchers have found a new family of therapeutic agents that interferes with the ability of estrogen to stimulate the growth of breast cancer cells. The results of the new study will be presented by Nicole Patterson at The Endocrine Society's 90th Annual Meeting in San Francisco. The cell-ba...

U.S. Childhood Cancers Vary by Sex, Region

Pediatric malignancies are more common in the Northeast, and boys are at higher risk than girls, study finds,,,, MONDAY, June 2 (HealthDay News) -- A sweeping government study of childhood cancers has found numerous differences in cancer types depending on a child's age, sex, race and...

Kidney Cancers More Likely to Be Diagnosed Early

Widespread use of medical imaging now catching smaller tumors at treatable stages MONDAY, May 19 (HealthDay News) -- Compared to a decade ago, kidney cancer patients in the United States are much more likely to be diagnosed with smaller tumors in the earliest, most treatable stage of t...

Majority of kidney cancers diagnosed at earliest stage

Patients in the United States today are now much more likely to be diagnosed with smaller tumors, in the earliest, most treatable stage of kidney cancer than a decade ago, leading to a slightly higher survival rate, according to the results of a national study led by a UC San Diego Medical Center ...

Potential viral therapy weapon for difficult cancers is safe and effective in study

CINCINNATI Combining a herpes virus genetically altered to express a drug-enhancing enzyme with a chemotherapy drug effectively and safely reduced the size of highly malignant human sarcoma grafted into mice. This new finding may add to the growing arsenal of so called oncolytic viruses under dev...

Genomic Profiling of Breast Cancers a Better Treatment Tool

Findings point to personalized therapies that help predict disease recurrence TUESDAY, April 1 (HealthDay News) -- Determining the genetic profile of a breast tumor, along with an assessment of a patient's clinical characteristics, can help predict prognosis and guide treatment choices...

Targeting aggressive breast cancers by putting them to sleep

It is well established that Id1, a gene normally produced only in embryonic development, is reactivated in many 'solid' cancers, or carcinomas. In the case of breast cancer, the Id1 gene is active only in the more aggressive and metastatic varieties of cancer. Typically those cancers do not pos...

DNA detectives find genetic markers for lung cancers most likely to recur

Researchers at the Johns Hopkins Kimmel Cancer Center have uncovered clearly recognizable genetic alterations in tumors and tissue removed from patients with early-stage lung cancers that look like good predictors of which of these cancers are more likely to recur. The discovery, they say, coul...

Carb Intake, Obesity Tied to Rise in Esophageal Cancers

Increased dietary intake of these refined compounds mirrors growth of disease, study says FRIDAY, Feb. 29 (HealthDay News) -- There may be a link between rising rates of carbohydrate intake and obesity and the increasing number of esophageal cancer cases in the United States, a new stu...

Heart Hormones Beat Back Cancers in Mice

One hormone cured 80 percent of pancreatic cancers, two-thirds of breast cancers, researcher says THURSDAY, Feb. 28 (HealthDay News) -- New research offers early evidence that hormones produced by the heart to control both blood pressure and volume could be harnessed to treat -- and po...

Hormone refractory prostate cancers more likely to spread to other organs

Prostate cancers that are resistant to androgen deprivation therapy are more invasive and more likely to spread to other organs than androgen dependent prostate cancers, UCLA cancer researchers have found. Virtually all prostate cancers are androgen dependent at first, but they progress and be...

Many Prostate Cancers Will Not Need Treatment

Major study finds most older men will die of other causes WEDNESDAY, Feb. 13 (HealthDay News) -- One of the largest studies of its kind concludes that most older men with early prostate cancer do not shorten their survival odds if they adopt a "wait-and-see" approach to the disease. ...