Stem cell treatment for brittle bones in the womb
The extraordinary results of an in utero stem cell treatment could lead to a new
treatment for babies with brittle
bones, as well as a range of other disabling
conditions, according to a maternal-fetal medicine researcher, now based at The
University of Queensland (UQ).
Action Medical Research h...
Stem Cell Treatment may Prolong Lives of Children With Brittle Bone Disease
Researchers at Imperial College London have found that injections of stem cells during the gestation period may help prolong the lives of children with brittle
bone disease , osteogenesis imperfecta (OI).
The genetic defect, detected in human foetuses by DNA testing or ultrasound, disrupts ...
Researchers Discovered the Gene Responsible for Brittle Bone Disease
Researchers at the National Institutes of Health have discovered that a previously unexplained fatal form of Osteogenesis //Imperfecta--a disorder that weakens bones and which may cause frequent fractures--results from a genetic defect in a protein involved in the production of collagen.
Teriparatide for Brittle Bone Disorder
Researchers are seeking a treatment and thereby finding a drug which can prevent the further breaking of the bones of patients suffering// from osteogenesis imperfecta (OI). Jimmy Fox is one of them though he is not suffering from that disease he still wants to be part of the team in finding the dr...
Stem of Hope: Stem Cell Research Acquires a Brittle Star As A model Brittle
star is forming the basis upon which Scientists at the Royal Swedish Academy of Sciences Kristineberg Marine Research Station are studying// stem cells with the capacity to probe into human and vertebral research, without having to bother about ethical issues.
Amphiura filiformis, o...
Use parathyroid hormone to fight brittle bone disease
A study conducted on more than 1600 women reveals that parathyroid hormone (parathormone) increases the patient’s bone density and cut the risk of fractures in them. The same hormone is also useful in regulating calcium levels in the body.
The new aspect of the hormone guarding aga...
Vitamin Shields Brittle Bones
Osteoporosis, wherein the density of the bone is lost and becomes brittle, is one of the dreaded complications in women after they attain their menopause. This happens as a result of decreased levels of estrogen, which is responsible for maintaining the bone density.
Dr. Sunil J. Wimalawansa, of...
Vitamin D Linked to HDL Cholesterol - Shaklee Corporation Research Links Vitamin D with Key Biomarkers for Metabolic Syndrome and Heart Disease
... vitamin D to address the suboptimal vitamin D blood levels found in many Americans. Researchers have linked low vitamin D intakes to osteoporosis or brittle
bones, high blood pressure, heart disease, autoimmune diseases and certain cancers.
This cross-sectional study assessed the relationships between...
America's Beauty Show Challenges Toxic Salons
...itional poorly recognized danger from salon and personal use relates to hair straighteners based on thioglycolic acid. Besides causing hair to become brittle
and break, they can also irritate the scalp and cause pustular and allergic reactions.
Of particular concern are hair dyes. About 35 percent of...
Arm Fractures Indicate Greater Risk of Hip Fractures in Elderly Patients
... subsequent fracture."
"The older population is at a greater risk for fall-related fractures, due to the fact that their bones are generally more brittle
than the younger population," Dr. Clinton adds. "These types of low-energy fractures are referred to in the literature as 'fragility fractures.'"
Osteoporosis Drug Prompts Increase in Certain Bone Cells
... News) -- Women who took the osteoporosis drug Fosamax for up to three years saw an increase in their number of osteoclasts, or cells that remove old, brittle
bone, a new study says.
These women also had "giant" osteoclasts -- single cells fused together -- with as many as 40 nuclei. Normally, one would s...
New study shows that a cough medicine ingredient could effectively treat prostate cancer
...d to slow the progression of advanced prostate cancer. Side effects resulting from these treatments include impotence, incontinence, fatigue, anemia, brittle
bones, hair loss, reduced appetite, nausea and diarrhea. No toxic side effects were observed in the laboratory study of noscapine.
American Academy of Dermatology: How You Feel on the Inside Could be Affecting How You Look on the Outside
...tice that their hair is
thinning, their skin is inflamed or their nails are brittle
-- which can be
physical manifestations of their mental state. These unwant...d, result in acne lesions that
are more inflamed and more persistent, cause brittle
nails and ridging of
the nails, cause hair loss, cause or worsen hives, and...
Genetic disorder sheds light on enzyme's role in bone metabolism
...nown as cathepsin K which hampers osteoclasts (the cells that break down bone in bone modeling and repair), leading to poor bone resorption and dense, brittle
Cathepsin K's role in bone metabolism has largely been studied using mouse models, but a new study examines the enzyme's role in bone resor...
Dr. Lark Creates Nutritional Supplement to Restore Thick Hair and Strong Nails
...FAs) are critical to bring luster back to dull and brittle
hair and nails. Plus, they're necessary for hydrat... B-complex vitamins, biotin is known to strengthen brittle
fingernails in humans. It also has antioxidant eff...tion increases nail plate thickness in people with brittle
nails. Silica--This critical nutrient makes hai...
Live to 100 ... And Feel Great
...ease endurance. It may
also promote heart health.
-- Calcium is a must: Calcium is necessary for maintaining strong
bones, which tend to become more brittle
as one ages. However, taking
calcium alone can contribute to constipation, which is why Dr. Oz
recommends taking calcium with magnesium for optimal he...
July 2008 Mayo Clinic Women's HealthSource Highlights Vitamin D, Savvy Use of Sunscreen and Gastrointestinal Upset and Celiac Disease
...and Much More
Researchers identifying new health benefits
Vitamin D is essential to strong bones. Inadequate vitamin D can lead
to osteoporosis, a brittle
Recently, researchers have found that vitamin D may help reduce the
risk of other diseases. The July issue of Mayo Clinic Women's Heal...
Do Antidepressants Make Bones Brittle?
...ee if there are any effects from the drugs on growing bones. The researchers want to determine if there's a genetic predilection for osteoporosis, the brittle
bone disease that can lead to fractures, that's induced by the antidepressants.
While the studies suggest an association between antidepressant use...
2008 NAC Kids Olympics Celebrates the Achievements and Persevering Spirits of Hundreds of Children with Disabilities and Chronic Illnesses on Saturday, June 21, 2008 at Riverbank State Park
...0% use wheelchairs. Diagnoses
include spina bifida, cerebral palsy, muscular dystrophy, sickle cell
disease, cancer, HIV/AIDS, traumatic brain injury, brittle
autism or other chronic illnesses or disabilities. Through intensive family
support, medical, mental health, educational, and recreation...
Stem Cells Might Treat Tough Fractures
... who lack the proper healing process and to individuals prone to broken bones, such as those with osteoporosis and the rare genetic condition known as brittle
bone disease," senior author Dr. Anna Spagnoli, associate professor of pediatrics and biomedical engineering in the UNC School of Medicine, said in a ...
American Chemical Society's Weekly PressPac -- June 4, 2008
...gredient in composites and other materials in a wide range of products. Although cellulose-based composites have high strength, existing materials are brittle
and snap easily when pulled.
The study described a solution to this problem. It involves exposing wood pulp to certain chemicals to produce cellulo...
Soccer's a Winner for Building Bone Health in Girls
...ty during the teen years is considered crucial for healthy bone development, helping to ward off osteoporosis, the disease that causes bones to become brittle
and break later on in life. Peak bone mass is typically achieved by age 30, according to the National Osteoporosis Foundation.
"It's those years of...
Press Preview to Unveil Miracle Manny
...mmigrant now living in Chicago -- exhibiting haunting drawings of soldiers wounded in Iraq -- and Jon Wos, an Oshkosh, WI artist whose genetic brittle
bone condition has inspired prize-winning glass sculptural self- portraits of his lifetime of fractures and surgeries.
-- eMotion Pictures is fr...
Dental Erosion on Rise in U.S.
...nks, some fruit juices and herbal teas.
"When consumed in excess, these products can easily strip the enamel from the teeth, leaving the teeth more brittle
and sensitive to pain. The acids in these products can be so corrosive that not even cavity-causing bacteria can survive when exposed to them," Amaech...
Drugs to bulk up muscles may make injuries more likely
...hey may also bring a troubling side effect small, brittle
tendons that could make muscle injuries more likel...gin with, and get stiffer with age. If tendons are brittle
and short, as they were in myostatin-lacking mice ...ently in people with muscular dystrophy so short, brittle
tendons could aggravate the problem if myostatin i...
Tel Aviv University gives preemies a fighting chance
...re and more than one in ten infants in the U.S. is its future is already compromised. One of the common problems associated with premature births is brittle
bones, or osteopenia of prematurity (OOP). It can cause bone fractures and rickets in the infant, and osteoporosis later in life.
Tel Aviv Univers...
... While everyone knows that
stress can take a toll on a person physically and psychologically, it also
can lead to dermatologic problems, such as acne, brittle
nails or even hair
loss. Speaking today at the American Academy of Dermatology's Skin Academy
(Academy), dermatologist Flor A. Mayoral, MD, FAAD, cli...
FDA Advisory Committee Votes in Favor of Earlier Use of Phosphate Binders in Stage 4 Kidney Disease Patients With Hyperphosphatemia
...isorder of mineral and
bone metabolism due to CKD. CKD-MBD often manifests as hyperphosphatemia,
which causes bone disease characterized by bone pain, brittle
skeletal deformities and fractures, and vascular or other soft tissue
calcification. Evidence also shows that hyperphosphatemia contributes to
International study strengthens case for daily calcium pill
...ular events such as strokes and heart attacks," Dr Tang says.
If mineral loss from the bones is left unchecked over time it will make bones porous, brittle
and prone to fracture - a condition called osteoporosis.
Two million Australians have osteoporosis and the disease costs the nation's economy $7.4 ...
Protein That may Prevent Eye Damage in Premature Babies Identified
In newborns with the disease, oxygen-starved areas of the retina compensate by rapidly growing new blood vessels, but these new vessels are brittle
"We've identified a protein that is part of the body's natural defenses in oxygen-deprived conditions," said Maria B. Grant, M....
Women Urged to Be Wary of Ads Promoting Unwanted Drugs
...ing Fosamax over the long term, the jawbone will start to crumble. And some research now suggests that the type of new bone created by Fosamax is more brittle
and more prone to fracturing over time.
But that side of the story takes a while to get through. Meantime the coffers of the drug firm should be...
Scientists Create Fire-proof, Eco-friendly Plastic
...lastic: it is clear, flexible, durable and much cheaper to make than the high-temperature and heat-resistant plastics in current use, which tend to be brittle
and dark in color.
The great thing about BHDB is that its really a two-birds-with-one-stone approach for a new polymer, says Coughlin. It is e...
Give Up Sugar to Keep Yourself Young
...gen is your skins mattress and the elastin fibres are the coils holding it together. The sugar attacks these fibres, making them less elastic and more brittle
so they break. The result is that your once-youthful skin starts to sag and look old, he added.
The glycation process makes these fibres to ch...
Researchers Develop Material That Self Heals Like Human Skin
...ed and the ink which liquefied was extracted, leaving behind a substrate with a network of interlocking microchannels.
In the final steps, a brittle
epoxy coating was deposited on top of the substrate, to fill the network with a liquid healing agent. The coating and substrate were also bent until a...
Anti-fungal Drug Block Angiogenesis
Itraconazole is a well known antifungal drug and it works by blocking a key enzyme for making fungal cholesterol and thus making them brittle
and split apart.
"The best outcome was to find an already approved drug that worked, and the fact that we did was very satisfying," says Liu, w...
Measuring Calcium Intake Help to Identify Osteoporosis in Prostate Cancer Patient
...ts who hadn’t received hormone treatment also developed osteoporosis."
Osteoporosis is caused by loss of bone mineral density, which makes bones brittle
and significantly more likely to fracture. It is more common in older people and has been strongly linked to hormonal changes, such as the female meno...
Estradiol Guards Against Osteoporosis
...estrogen is reduced, as occurs normally in postmenopausal women and pathogenically after exposure to radiation or chemotherapeutic drugs, bones become brittle
and break easily. However, the mechanisms involved aren’t clearly understood.
The new study found that one way estradiol helps to maintain bone ...
Taking Drugs for Heartburn may Cause Fractured Hip
...n the intestinal tract in order to dissolve calcium salts, so that it may be absorbed into the cells. Without calcium the bones will ultimately become brittle
and suffer fractures.
Fractures in the hip are often life threatening if it occurs in the elderly. Unless left with no other option, doctors should...
Osteoporosis Meds and Jaw Pain: What's the Risk?
...December issue of Mayo Clinic Health Letter.
In contrast, the health risks associated with osteoporosis — a disease that causes bones to become brittle
and to fracture — are high. More than half of Americans over 50 either have or are at risk of developing osteoporosis. If a fracture occurs, you're at...
Botox – The 'Celebrity' Dru
...dismal emotions that are attached to growing old. While most humans romanticize youth, they shrink from the thought of greying hair, sagging flesh and brittle
bones, which are identified as the infirmities of old age.
With the changing trends, the concept of ageing gracefully by enhancing one’s inner be...