Results of phase III study on Labopharm's novel antidepressant published in Psychiatry (Edgemont) Journal
- Company to Also Present Clinical Data at
Upcoming Scientific Meeting -
LAVAL, QC, May 19 /PRNewswire-FirstCall/ - Labopharm Inc. (TSX: DDS; NASDAQ: DDSS ) today announced the publication of Extended Release Trazodone in Major Depressive Disorder:...
Participants in antidepressant drug trials are atypical patients, UT Southwestern researchers report
DALLAS May 13, 2009 One reason antidepressant
medication treatments do not work as well in real life as they do in clinical studies could be the limited type of study participants selected, researchers at UT Southwestern Medical Center have found.
"We are basing our judgment of clinical care ...
AstraZeneca Licenses Novel Antidepressant Compounds Discovered by Mayo Clinic and Virginia Tech Collaboration
Agreement includes research collaboration to generate follow-up TRI compounds
WILMINGTON, Del., Feb. 9 /PRNewswire-FirstCall/ -- AstraZeneca, Mayo Clinic, and Virginia Tech Intellectual Properties Inc. today announced that AstraZeneca has licensed a portfolio of preclinical Triple Reuptake In...
Mylan Receives Final FDA Approval for the Generic Version of the Antidepressant Sarafem(R) Pulvules(R) Capsules
PITTSBURGH, Nov. 18 /PRNewswire-FirstCall/ -- Mylan Inc. (NYSE: MYL ) today announced that its subsidiary, Mylan Pharmaceuticals Inc., received final approval from the U.S. Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for Fluoxetine Capsules USP, 10 mg and 2...
Gene Variations May Predict Antidepressant Response
Finding could help advance individualized medicine for psychiatric patients
FRIDAY, July 18 (HealthDay News) -- Scientists may have found more evidence that a person's genetic make-up may help determine whether or not they respond to the antidepressant
New study replicates association between genetic variation and antidepressant treatment response
Philadelphia, PA, July 15, 2008 Pharmacogenetics, the study of genetic variation that influences an individual's response to drugs, is an important and growing focus in all of medical research, including psychiatry. It is a complex field, however, revealed by the lack of consistent and replicabl...
Mylan Announces Final FDA Approval for Generic Version of Antidepressant Effexor(R)
PITTSBURGH, June 16 /PRNewswire-FirstCall/ -- Mylan Inc. (NYSE: MYL )
today announced that its subsidiary, Mylan Pharmaceuticals Inc., has
received final approval from the U.S. Food and Drug Administration (FDA)
for its Abbreviated New Drug Application (ANDA) for Venlafaxine
Hunger hormone increases during stress, may have antidepressant effect
DALLAS June 15, 2008 New research at UT Southwestern Medical Center may explain why some people who are stressed or depressed overeat.
While levels of the so-called "hunger hormone" ghrelin are known to increase when a person doesn't eat, findings by UT Southwestern scientists suggest that t...
Inflammation, depression and antidepressant response: Common mechanisms
Major depressive disorder is a common and complex condition that impacts about 15% of the population of the United States, yet very little is known about the mechanisms behind the psychiatric disorder. What is known is that there are clinical parallels between depressive symptoms and the sympto...
A Drug That Carries a Lower Risk of Weight Gain Than AstraZeneca's Seroquel and Has Antimanic and Antidepressant Effects Would Earn a 30 Percent Patient Share in Bipolar Disorder Treatment
Seroquel's Successor, Seroquel XR, Will Earn a 16 Percent Patient Share in the Bipolar Disorder Market by 2016, According to a New Report from Decision Resources
WALTHAM, Mass., April 22 /PRNewswire/ -- Decision Resources, one of the
world's leading research and advis...
Researchers explore the antidepressant effects of ketamine
Philadelphia, PA, February 21, 2008 Drug treatments for depression can take many weeks for the beneficial effects to emerge. The excruciating and disabling nature of depression highlights the urgency of developing treatments that act more rapidly. Ketamine, a drug used in general medicine as an...
Researcher of the University of Navarra discovered potential antidepressant compounds
This release is also available in Spanish .
Luis Berrade, a researcher with the Drug R&D Unit of the University of Navarra, has discovered new compounds with the potential for anti-depressant activity. All told, the chemist of the School of Sciences synthesized 51 compounds whose biologic...
Genetic difference predicts antidepressant response
Researchers have identified subtle genetic variations that predict the efficacy of two widely used antidepressant
drugs. They found that certain variants in the gene for a protective transporter protein that pumps drugs and other substances out of the brain compromise the effectiveness of the anti...
Antidepressant Effectiveness Probably Overstated: Report
Researchers unclear on whether it's reluctance to submit or reluctance to publish negative findings
WEDNESDAY, Jan. 16 (HealthDay News) -- A systematic review of studies on antidepressants concludes that the positive effects of these drugs are probably overstated in the medical litera...
Youth Suicide Warnings Are Slowing Antidepressant Sales
Study finds drop in SSRI prescriptions for children and adults
MONDAY, Jan. 7 (HealthDay News) -- Warnings about the risk of suicidal thoughts and behaviors in young people who take antidepressants may be slowing the pace of antidepressant
prescriptions, new research suggests.
Genetic test announced for suicidal ideation in patients using antidepressant drugs
Boulder, CO, October 1, 2007 NeuroMark, a Boulder, Colorado company, announced today the immediate availability of a genetic test to identify people at risk of suicidal ideationthoughts of committing suicidewhen prescribed an antidepressant
drug. The test, called the Mark-C test, is expected to ...
Genes Might Predispose Antidepressant Users to Suicidal Thoughts
Someday, DNA tests might spot those most at risk, experts say
THURSDAY, Sept. 27 (HealthDay News) -- Variations in two genes may help spur suicidal thinking in individuals taking a commonly prescribed antidepressant, research suggests.
Although preliminary, the findings could pave t...
Labopharm completes enrolment for Phase III clinical study for its once-daily trazodone antidepressant drug
LAVAL, QC, Sept. 25 /PRNewswire-FirstCall/ - Labopharm Inc. (TSX: DDS;
NASDAQ: DDSS) today announced that it has completed patient enrolment in
its North American Phase III clinical trial for its once-daily formulation
of the antidepressant
trazodone (study 04ACL3-001). More than 400 patients
Labopharm receives complete response letter from the U.S. FDA for novel antidepressant
LAVAL, QC, July 20 /PRNewswire-FirstCall/ - Labopharm Inc. (TSX: DDS; NASDAQ: DDSS ) today announced it has received a complete response letter from the U.S. Food and Drug Administration (FDA) for the new drug application (NDA) submission of its novel formulation of the antidepressant
Marijuana-like brain chemicals work as antidepressant
Irvine, Calif., Nov. 5, 2007 American and Italian researchers have found that boosting the amounts of a marijuana-like brain transmitter called anandamide produces antidepressant
effects in test rats.
Led by Daniele Piomelli, the Louise Turner Arnold Chair in Neurosciences and director of the ...
Reduction in Antidepressant Leads to Suicidal Risks
Regulatory warnings regarding the risk of suicidal thoughts and behaviors appear to be associated with reductions in the number of antidepressant
medication prescriptions among children and adolescents covered by Tennessees expanded Medicaid program.
Antidepressant medications are frequently ...
Lupin Gets Tentative Nod from FDA for Antidepressant Drug
Leading pharmaceutical company Lupin Ltd has received tentative approval from the US Food and Drug Administration (FDA) for its generic drug Sertraline Hydrochloride for// treatment of major depressive disorder.
Mumbai based Lupin's Sertraline Hydrochloride tablets will be the AB-rated generic...
Certain antidepressant drugs associated with pronounced suicidal tendencies
Antidepressants such as Prozac, Paxil and Zoloft, prescribed to the elderly, has shown a tendency of inducing suicidal thoughts in its recipients//, especially in the first month of its use, as compared to other types of medication to treat depression.
Earlier studies had shown the prevalence ...
Newborns Affected By Antidepressant Intake Of Mothers
Researchers have advised expectant mothers to reduce the intake of anti-depressant drugs, as it is likely to affect the new born with withdrawal symptoms. // The newborn babies of such mothers display symptoms like disturbed sleep, gastrointestinal problems, high-pitched crying, and tremors within...
Non-addictive antidepressant drug
Professor Gabriella gobbi and his team from Universite de Montreal have found that the new drug URB597 increases the level of endocannabinoids by blocking the degradation in the brain and relaxes depression. //Endocannabinoids are chemicals present in brain which is responsible for relaxing brain, ...
Cannabinoids - Antidepressant And Inflammatory Bowel Disease Treatment
This news article discusses both the treatments of giving Cannabinoids for depression and inflammatory bowel disease.
Cannabis and Cannabinoids:
Cannabinoids is a chemical compound found in Cannabis//. Cannabinoids are an exciting new area for medical research, but it is important to re...
Pharmac to Phase Out Aropax, Well-known Antidepressant
Government Drug Agency, Pharmac, is in the process of doing away with a commonly used antidepressant, Aropax. //
Pharmac intends to phase out the ‘Aropax’ brand of paroxetine and bring in the generic alternative ‘Loxamine’. It is estimated that Aropax is used by about 49,000 New Zealanders. ...
U.S. Spending on Mental Health Care Soaring
...ther mental health woes almost doubled, from 19 million to 36 million.
The new statistics come on the heels of a study, released Monday, that found antidepressant
use among U.S. residents almost doubled between a similar time frame, 1996 and 2005.
Spending on mental illness showed a faster rate of growth over...
Antidepressant Use in U.S. Has Almost Doubled
MONDAY, Aug. 3 (HealthDay News) -- antidepressant
use among U.S. residents almost doubled between 19...es back to the 1980s, with the introduction of the antidepressant
The study found that 5.84...ed despite a "black box" warning mandated for many antidepressant
medications by the U.S. Food and Drug Administrati...
INVEGA(R) Approved as the First and Only Treatment for Schizoaffective Disorder
... given at a stable dose within 30 days of screening. Approximately half the subjects enrolled received ongoing treatment with a mood stabilizer and/or antidepressant
during the studies. The most commonly used mood stabilizers were valproate and lithium. The most commonly used antidepressants were SSRIs and SNRIs.
Almost 1 quarter of Spanish women take antidepressants
...anxiety (9.9%) and insomnia (3.3%).
The scientists also found that benzodiazepine use increases with age. However, they did not find the same with antidepressant
use. "We think that greater training is needed in identifying SLE and family dysfunction, and recording these in patients' records in order to help ps...
The Neutraceutical Company Announces Powerful New 'Feel-Good' Product
...epression. Clinical studies have proven that this proprietary extract supports healthy levels of serotonin, operating in a similar way to prescription antidepressant
drugs -- but without the troublesome side effects. Our suppliers have located a unique, potent source that makes it commercially viable for the first ...
Depression Poses Pregnancy Risks
...d. "It can be harmful to your baby."
What about antidepressant
use during pregnancy?
"What I tell patients who...uding the suggestion that pregnant women avoid the antidepressant
paroxetine (Paxil). In 2005, the U.S. Food and Dru...that babies born to women who are taking a type of antidepressant
known as an SSRI (selective serotonin reuptake inh...
Antidepressants aid electroconvulsive therapy in treating severe depression
... WINSTON-SALEM, N.C. Combining antidepressant
drugs with electroconvulsive therapy (ECT) does a ...ack of prior information on the topic of combining antidepressant
medications with ECT, the American Psychiatric Ass...y loss.
The researchers found that using either antidepressant
during ECT improved depression more than ECT alone...
Anti-Smoking Drugs Get FDA 'Black-Box' Warning
...ficult and complex."
The FDA's review of consumers using nicotine patches did not find a link between patches and psychiatric side effects.
Wellbutrin, which contains the same active ingredient as Zyban, already carries a black-box warning.
For more on how to quit ...
Michael Jackson Joins Tragic List of Accidental Celebrity Deaths Caused by Prescription Drugs, Says eDrugSearch.com
...s at his home.
12. NICK DRAKE. The influential singer-songwriter died at his childhood home in the U.K. in 1974 from an accidental overdose of the antidepressant
13. PAIGE SUMMERS. The 1998 Penthouse Pet of the Year was found dead in her fiance's home in 2003 from a combination of the painkil...
Care management reduces depression and suicidal thoughts in older primary care patients
...atment according to accepted practice guidelines, monitored treatment response and provided follow-up over two years. Practice guidelines included the antidepressant
citalopram (Celexa), with the option of other drugs or psychotherapy.
After two years, nearly 90 percent of patients in the PROSPECT care managemen...
Preliminary report on antidepressants published
... therapy and in the prevention of relapse into seasonal affective disorder, while on the other hand the data provided no indications of harm. The only antidepressant
that was compared with bupropion XL in trials was venlafaxine XR. Bupropion XL showed inferiority to venlafaxine XR in acute therapy. Further informat...
Lilly Resubmits Cymbalta(R) Supplemental New Drug Application for Chronic Pain to U.S. Food and Drug Administration
...a is approved only for adults 18 and over.
Cymbalta is not for everyone. Patients should not take Cymbalta if they have recently taken a type of antidepressant
called a monoamine oxidase inhibitor (MAOI), are taking Mellaril(R) (thioridazine), or have uncontrolled glaucoma. Patients should speak with their do...
Celexa May Not Help Kids With Autism
...s, but not all agree,,,,
MONDAY, June 1 (HealthDay News) -- In contrast to the assumptions of some doctors, new research suggests that the antidepressant
Celexa does not help relieve repetitive behaviors often seen in children and teens with autism.
But the findings still need to be confirmed by oth...