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Altered in Medical News

Reversing effects of altered enzyme may fight brain tumor growth

An international team of scientists from the Moores Cancer Center at the University of California, San Diego, the University of North Carolina and several institutions in China have explained how a gene alteration can lead to the development of a type of brain cancer, and they have identified a co...

As a Result of the FDA Investigation Into TNF-Alpha Inhibitors, 30 Percent of Surveyed Rheumatologists Have Altered Their Prescription Patterns for Juvenile Idiopathic Arthritis

Twenty Percent of Surveyed MCO Pharmacy Directors Say They Will Alter Reimbursement of TNF-alpha Inhibitors for Juvenile Idiopathic Arthritis and Pediatric Crohn's Disease, According to a New Report from Decision Resources WALTHAM, Mass., March 26 /PRNewswire/ -- Decision Resources, one of th...

Effectiveness of Progesterone in Reducing Preterm Births May Be Altered by Genetic Predisposition

March of Dimes Awards Abstract at SMFM Meeting. SAN DIEGO, Jan. 30 /PRNewswire-USNewswire/ -- New research that may explain why taking progesterone to prevent preterm birth is only effective for some women was unveiled today at the 29th Annual Society...

Premature babies have altered sensory responses in later life

Premature infants who need intensive care or surgery are less sensitive to thermal (hot and cold) sensations later in life, according to research conducted at UCL (University College London). The study, published in the journal Pain , suggests that pain and injury related to major medical interve...

Undiagnosed OSA patients have altered cardiovascular responses during exercise recovery

WESTCHESTER, Ill. A study published in the January 1 issue of the journal SLEEP finds that people with untreated obstructive sleep apnea (OSA) have altered cardiovascular responses during recovery from maximal exercise. These results suggest an imbalance in the autonomic control of heart rate du...

Penguins Altered Diet When Humans Began Hunting Whales and Seals

Adlie penguins living in Antarctica switched from eating fish to krill (shrimp-like marine invertebrate animals) around the time that humans began hunting seals and whales, ancient eggshell fragments reveal. According to Steven Emslie of the University of North Carolina in Wilmington, and...

Genetically Altered Cells Prevent Lethal Infections in Substituted Skin

Researchers have developed modified skin cells which on being added to cultured skin substitutes, may help fight off potentially lethal infections in patients with severe// burns. Cultured skin substitutes are grown in a laboratory using cells from a burn patient's own skin. These cells are c...

The Immune System May Be Altered By Certain Chemicals

A new research have found out that certain inhaled asthma medications and similar chemicals produced in our body during times of high stress // may worsen conditions like lupus, heart failures, asthma and other conditions that involve inflammation. The scientific team led by Raymond Penn, Ph.D....

Schizophrenia Complicates With Altered Receptor Activity

When analyzing the neuronal receptor activity in the postmortem brain tissue from patients with schizophrenia, researchers at the University of Pennsylvania //School of Medicine, in collaboration with scientists at the City University of New York, have found a striking dysregulation in its function...

Cocaine Acts As Suppressant Not Stimulant In Genetically Altered Mice

Researchers at the Ohio State University have found that cutting off the reward pathway of cocaine on mice by genetically altering a vital target in the brain of the mice makes them shun cocaine//. Howard Gu, the study’s lead author and an associate professor of pharmacology and psychiatry at...

Tooth Decay Bacteria Unaffected By Altered Biochemical Pathway

Streptococcus mutans, the bacteria responsible for causing tooth decay, are able to survive and multiply without an essential biochemical pathway that is considered// vital for the survival of normal cells. Researchers at the University of Florida have revealed that the tooth decay causing bact...

Women With Anorexia Have Altered Brain Activity

People suffering from anorexia nervosa have the similar brain activities that are associated anxiety and other emotional disorders. // The study was published in the September issue of Archives of General Psychiatry . Previous evidence has suggested that alterations in the activity of serotonin...

American Health Assistance Foundation & Asbury Methodist Village to Host Special Community Screening and Discussion of the HBO Series, The Alzheimer's Project

...ade of events including accumulation of free radicals, which can run amuck and ultimately lead to Alzheimer's disease. His work also looks at how the altered calcium signaling affects brain cell pathways and communication," notes Guy Eakin, Ph.D., Director of Research Grants, American Health Assistance Foun...

Sperm Cell Insights May Aid Stem Cell Research

...m from Johns Hopkins University School of Medicine in Baltimore genetically altered male fruit flies to reduce the activity of two proteins called Jak and STAT... testis to zero and found that only 60 percent of testis in the genetically altered flies regained stem cells, compared with 97 percent of testis in normal fli...

Dementia induced and blocked in Parkinson's fly model

...icine in St. Louis have modeled Parkinson's-associated dementia for the first time. Scientists showed that a single night of sleep loss in genetically altered fruit flies caused long-lasting disruptions in the flies' cognitive abilities comparable to aspects of Parkinson's-associated dementia. They then bloc...

Comprehensive Look at Rare Leukemia Finds Relatively Few Genetic Changes Launch Disease

... the development of AML may require fewer genetic alterations than other cancers and that a very limited number of biological processes may need to be altered in hematopoietic stem cells, multi-potential progenitors or committed myeloid progenitors to convert them from a normal cell to AML," the authors note...

Kaiser Permanente to Provide Calorie, Nutrition Information on Cafeteria Menus

...f the respondents at the menu board sites noticed the calorie information and nearly one-third of those who noticed the information reported that they altered their purchase as a result of the information. This is one of few studies of its kind to track the impact of menu board labeling on purchasing behavio...

New Anesthesia May Be Safer for Critically Ill

...eral anesthesia has been developed that may be safer for some patients. Preclinical studies done on rats put under with MOC-etomidate, a chemically altered version of the anesthetic etomidate, found the drug does not cause blood pressure to drop suddenly or slow adrenal gland activity, common side effect...

Mass. General team develops potentially safer general anesthetic

...or critically ill patients. In the August issue of Anesthesiology , they describe preclinical studies of the drug called MOC-etomidate a chemically altered version of an exiting anesthetic which does not cause the sudden drop in blood pressure seen with most anesthetics or prolonged suppression of adrena...

Studies Show Genetic Activity of Antioxidants

...its in the aorta, the main artery of the heart. The researchers then isolated genetic material from the mice and exposed it to curcumin. They found altered expression of 2,252 genes, whose activity included cellular signaling and adhesion, inflammation and fat metabolism. The orange juice study was don...

New Gene May Signal Aggressive Breast Cancer

...oliferation. Next, researchers implanted cells with decreased RCP protein expression into mice with an immunodeficiency. Researchers found that the altered cells had less capacity for tumor growth and metastasis. According to the study, RCP overexpression also impacts the RAS protein, which previous re...

American Health Assistance Foundation & Asbury Methodist Village to Host Special Community Screenings and Discussion of HBO Series The Alzheimer's Project

...ade of events including accumulation of free radicals, which can run amuck and ultimately lead to Alzheimer's disease. His work also looks at how the altered calcium signaling affects brain cell pathways and communication," notes Guy Eakin, Ph.D., Director of Research Grants, American Health Assistance Foun...

Gene Connections Key to Brain Tumor Growth

..., up to 50 percent of the 30,000 to 40,000 genes in the human genome may be altered in glioblastoma. The key is discovering which changes are actually impo...he complex genetic changes leading to glioblastoma. These 31 genes were altered in up to 75 percent of glioblastomas, forming a landscape common to about t...

Drug rescues memory lost to Alzheimer's disease

...d in the July 15 edition of the Journal of Immunology . For 12 weeks, Tenner and colleagues added PMX205 to the drinking water of mice genetically altered to develop age-related Alzheimer's-like symptoms. The treatment occurred at an age when plaques were accumulating in their brains. Scientists gave ...

K-State scientist receives grant from National Institutes of Health to research cataracts

...true equilibrium conditions," Takemoto said. "This study will establish the presence of interactions and will determine whether these interactions are altered during cataractogenesis." ...

Simulating medical situations helps students learn, retain basic science concepts

...ical emergency. Students were told that the patient "SimMan," a computerized mannequin that can be programmed to have different medical problems had altered mental status, nausea and vomiting. A team of physicians played the roles of EMS workers, nurses and family members, and the students worked throu...

UCI Medical Affiliates, Inc.'s Internal Investigation Leads to SEC Action and Criminal Charges Against Former Executive Officer

...incurred, thereby causing the Company to overstate its net earnings in the affected periods. To justify capitalizing some of these expenses, Mr. Wells altered invoices from contractors performing work on his personal residences to indicate that the work was for one of the Company's facilities, and provided f...

Reglan Adverse Events More Than Doubled from 2006 to 2008

...ccording to articles published in the Archives of Internal Medicine and other medical journals. Symptoms of NMS include hyperthermia, muscle rigidity, altered consciousness, irregular pulse, blood pressure or heartbeat or other symptoms. “In addition to requiring the manufacturers to place a black ...

New study pinpoints difference in the way children with autism learn new behaviors

... structural and functional connectivity in the brain of children with autism. Additionally, researchers may study if patterns of motor learning can be altered to increase visual connections in specific regions of the brain. Through interventions such as cortical stimulation, biofeedback and behavioral approa...

Caffeine reverses memory impairment in Alzheimer's mice

...on memory from other lifestyle factors such as diet and exercise, Arendash said. The just-published Florida ADRC study included 55 mice genetically altered to develop memory problems mimicking Alzheimer's disease as they aged. After behavioral tests confirmed the mice were exhibiting signs of memory impai...

C-Section Stress Could Alter Baby's Immune Cells

...rolinska Institute in Stockholm, said in a news release from Wiley-Blackwell publishers. "Although the underlying cause is unknown, our theory is that altered birth conditions could cause a genetic imprint in the immune cells that could play a role later in life." Norman and his colleagues analyzed blood ...

Risk of cancer

...gthens the binding of a regulatory factor in cancer cells, which activates pathways that are central to the development of cancer. The impacts of this altered genetic regulation on cell division are probably mediated via the MYC cancer gene, which is one of the best known accelerator genes in cancer. Sing...

Smoking May Trigger Brain Damage

...tack healthy cells, resulting in severe neurological damage. The compound, NNK, is a procarcinogen, which means it becomes cancer-causing when it's altered by the metabolic processes of the body, the researchers wrote. NNK doesn't cause direct harm to brain cells, but appears to cause neuroinflammation th...

Making nanoparticles in artificial cells

...nels, like balloons tied to strings, and stand in a solution that is the same as the one inside them. The researchers working with Rumiana Dimova then altered this situation: they substituted the solution with the first ingredient for the nanoparticles with a second component. This causes no change inside th...

New research discovers link between smoking and brain damage

...arch centers on a compound known as NNK, which is common in tobacco. NNK is a procarinogen, a chemical substance which becomes carcinogenic when it is altered by the metabolic process of the body. Unlike alcohol or drug abuse NNK does not appear to harm brain cells directly, however, the research team bel...

Music Can Make the Heart Beat Faster

...cycles, without music. "I might implement a small pilot program on these subjects, not at rest but while they exercise," he said. "Are their responses altered by simultaneous music? These are debilitated coronary patients in whom small changes might be important." "One logical next step would be to encour...

Study finds that tobacco companies changed design of cigarettes without alerting smokers

...y the same brand of product are not made aware of how that product has been altered and what effect those alterations might have on their levels of addiction o...an result in significant design differences. The resulting product may have altered chemistry or delivery, yet the smoker is largely unaware of these changes. ...

Targeting tumor behavior may lead to new liver cancer drugs

..., Patel says. He notes that several new agents are in development for the disease, but each affects just one or another of the many processes that are altered in liver cancer cells. "We believe that targeting a certain type of tumor behavior might be helpful for liver cancer because many different biochem...

RNA snippet suppresses spread of aggressive breast cancer

...ncreasing miR-31 levels could affect metastasis, Valastyan introduced miR-31 into breast cancer cells that readily metastasize. After injecting these altered cells into mice, the mice had four to 40 times fewer metastases than mice injected with the unaltered cells. Valastyan says that quantifying miR-3...

Finding Raises Hope for Treating ALS

...aster progression. Another study, recently published online in the Proceedings of the National Academy of Sciences , found that mice genetically altered to have ALS experience cell damage well before protein aggregates start to appear, a time that coincides with telltale symptoms of the disease. "...
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