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Cardium Presents Gene Activated Matrix Technology and Update on Excellarate Clinical Development Program at ASGT Annual Meeting

SAN DIEGO, May 28 /PRNewswire-FirstCall/ -- Cardium Therapeutics (NYSE Amex: CXM ) and its subsidiary Tissue Repair Company (TRC) today announced a presentation entitled "Phase 2b Study of GAM501 (Ad5PDGF-B/Collagen) in the Treatment of Diabetic Ulcers" at the Late Stage Industry Clinical Trials...

Workplace Creativity Activated by Reflexology, Chair Massage

During the current recession, small businesses turn to reflexology and aromatherapy, as part of chair massage treatments in the workplace, to help promote well-being and increase productivity. Scientific studies back the anecdotal evidence from stressful offices around the US. ...

ICERx.org Activated to Provide Emergency Access to Prescription Medication Information for Hurricane Ike Evacuees

TAMPA, Fla., Sept. 12 /PRNewswire/ -- In the wake of the President's declaration of a state of emergency, ICERx.org (In Case of Emergency prescription history service) has been activated to provide licensed physicians and pharmacists caring for Hurricane Ike evacuees with private, secure onlin...

ACS Facilitates Emergency Prescription Assistance Program Now Activated in Southern Louisiana

DALLAS, Sept. 11 /PRNewswire-FirstCall/ -- Affiliated Computer Services, Inc. (NYSE: ACS ) today announced that it is facilitating the Emergency Prescription Assistance Program (EPAP), now activated for residents in southern Louisiana in the wake of Hurricane Gustav. The EPAP program, estab...

ICERx.org Activated to Provide Emergency Access to Prescription Medication Information for Hurricane Gustav Evacuees

TAMPA, Fla., Aug. 31 /PRNewswire/ -- In the wake of the President's declaration of a state of emergency, ICERx.org (In Case of Emergency prescription history service) has been activated to provide licensed physicians and pharmacists caring for Hurricane Gustav evacuees with private, secure onl...

Schizophrenia linked to dysfunction in molecular brain pathway activated by marijuana

PITTSBURGH, July 7 Alterations in a molecular brain pathway activated by marijuana may contribute to the cognitive symptoms of schizophrenia, according to a report in the July issue of Archives of General Psychiatry , one of the JAMA/Archives journals. Expression of the cannabinoid 1 receptor...

Scientists Identify Genes Activated During Learning and Memory

Researchers have long recognized that for learning and memory to take place, certain genes must be activated to alter neuron activity inside the brain//. Disruptions in normal gene expression within these neurons can lead to alarming consequences, such as seizures and epilepsy. But identifying and ...

Distinct Brain Sections Are Activated While Making Risky Decisions

Duke University Medical Center researchers have discovered that distinct regions of the human brain are activated when people are faced with ambiguous choices versus// choices involving only risk. The investigators found the reason behind why people make risky choices, and how such risk-taking can ...

Stroke victims have new hope with activated protein C

A new study by researchers from the University of Rochester, New York suggests that the activated protein C (APC), a protein with anti-inflammatory and anti-coagulant properties,which until now is being used to treat septic infections, may also help reduce the damage caused by stroke. Researchers w...

Cold, Flu or Pneumonia? Answer May Lie in Blood Test

...were infected with either a live cold virus, respiratory syncytial virus or influenza A virus, the researchers identified changes in 30 genes that are activated as the body responds to infection. The genomic signature is strong enough to reveal whether the infection is viral or bacterial and can identify wh...

Bellicum Pharmaceuticals Announces Initiation of Phase I/II Clinical Trial of Novel Vaccine for Patients With Advanced Prostate Cancer

...in 2010. BP-GMAX-CD1 is a novel cancer vaccine that can be precisely activated at an optimal time and location in the body. It is produced by genetically ... intradermal administration, these genetically modified dendritic cells are activated in draining lymph nodes by intravenous administration of AP1903, a small-mo...

The Reduction of Eye Fatigue Improves Vision in Older Subjects

...in. The researchers suggest that the underlying reason for the improved accommodation ability in the test subjects may be due to the positively activated functions of three muscles in the eye; the constrictor pupillae muscle and dilator pupillae muscle working in coordination with the ciliary muscle. A...

Nanotechnology Transforms Pain Relief

...ase is a nanosphere-encapsulated cooling system . Each nanosphere within the IcePearls(TM) system has a designated release time. Some nanospheres are activated right away, releasing the cooling complex as soon as MyOmega(R) is applied. Other nanospheres are encapsulated within microspheres, which have barrier...

Researchers Identify New Method to Selectively Kill Metastatic Melanoma Cells

...mbent of the Thelma Newmeyer Corman Endowed Chair in Cancer Research with the VCU Massey Cancer Center . According to Fisher, the pathway that is activated involves the melanoma differentiation associated gene-5, or mda-5, a gene initially cloned in Fisher's laboratory, that activates a protein called NOX...

Researchers identify new method to selectively kill metastatic melanoma cells

...ncumbent of the Thelma Newmeyer Corman Endowed Chair in Cancer Research with the VCU Massey Cancer Center. According to Fisher, the pathway that is activated involves the melanoma differentiation associated gene-5, or mda-5, a gene initially cloned in Fisher's laboratory, that activates a protein called NOX...

Food additive may one day help control blood lipids and reduce disease risk

...Metabolism and Lipid Research. "When we gave the animals fibrate drugs that activated PPAR-alpha, the mice returned to normal, leading us to suspect that fatty a...sion studies to isolate the phosphatidylcholine, or lecithin compound, that activated PPAR-alpha in the liver. One reason fatty acid synthase had never been co...

Scientists Track Impact of DNA Damage in the Developing Brain

...ed as the immature cerebellar interneurons, or progenitor cells, were poised to complete differentiation. In those cells, McKinnon said, loss of Xrcc1 activated the p53 pathway and blocked the cells from completing the cell cycle. "The cells appear to undergo permanent arrest," said McKinnon, noting it is one ...

Famous Names Get Single Neurons Fired Up

...three images of the TV host Oprah Winfrey, saw her name appear on a computer screen or listened to an electronic voice saying "Oprah." A single neuron activated in the hippocampus during the Oprah experiment, while a different neuron fired when the subject was "Star Wars" hero Luke Skywalker or another famous ...

Cardium Completes Sale of InnerCool Therapies Business to Royal Philips Electronics

... please visit www.cardiumthx.com . Cardium Therapeutics(TM) and Generx(TM) are trademarks of Cardium Therapeutics, Inc. Tissue Repair(TM), Gene activated Matrix(TM), GAM(TM) and Excellarate(TM) are trademarks of Tissue Repair Company. InnerCool Therapies ((R)) , InnerCool ((R)) , Celsius Control Sys...

Leukemia cells evade immune system by mimicking normal cells, Stanford studies show

...oser look determined why. "These cells have to cross fields of macrophages guarding these tissues," said Jaiswal. "Because the macrophages are also activated by the same stimuli, these elevated levels of CD47 protect the blood stem cells during this process." The macrophages' destructive power is exempl...

Critical link in cell death pathway revealed

...issues, such as in insulin-dependent diabetes. This cell death process is activated by proteins on the surface of cells. The most prominent of these cell surfa...s involved in the immune response), the killing is very direct. When FAS is activated a protein-destroying enzyme called caspase-8 is recruited and activated, le...

New drug candidate prolongs the lives of pancreatic cancer patients

...ast cancers as well as diabetes. Blocking the Ras protein Salirasib works by inhibiting a protein called Ras, which is known to be abnormally activated in one-third of human cancers. In cancer of the pancreas, mutant forms of Ras are found in up to 90% of all tumors. Salirasib's basic component, FTS, ...

Sweetwater Announces Trademarks of State-of-the-Art Healthy Drinking Water Purification Systems

...enic byproducts, along with herbicides and pesticides and other volatile organic compounds. The Urban Defender can be configured with either granular activated carbon for chlorine or the more highly reactive catalytic carbon for chloramine removal. Sweetwater's Kitchen Defender is a unique under sink wa...

Emdeon To Collaborate With Rx Response in Critical Pharmacy Disaster Reporting

...ment officials to communicate pharmaceutical needs and other issues which may impact the supply system. The Pharmacy Status Reporting Tool was first activated during the Kentucky ice storm of January 2009 with much success. "As an integral part of the pharmaceutical supply chain, we are eager to pa...

Max Muscle Sports Nutrition Answers Call For Safe Science-Based Weight Loss

...s, increase energy and elevate the body's metabolism." Max De-Lite activated Weight Loss Formula promotes weight loss and appetite suppression by contai...t and a deterrent on the fat you consume'. Store orders for Max De-Lite activated Weight Loss formula at the more than 150 Max Muscle Sports Nutrition stores...

Researchers map how staph infections alter immune system

...et more severe staphylococcal infections than others. By using gene expression profiling, a process that summarizes how individual genes are being activated or suppressed in response to the infection, UT Southwestern researchers pinpointed how an individual's immune system responds to a S. aureus infecti...

DNA-damaged cells communicate with neighbors to let them know they're in trouble

...st Francis Rodier, PhD, led the team that did the research in the Campisi lab. He was surprised to find that even though the DDR signaling process was activated inside the cultured human cells within minutes of the DNA damage, it took 24 to 48 hours for the damaged cells to start secreting the inflammatory sig...

Fluorescent probes may permit monitoring of chemotherapy effectiveness, Stanford study shows

...re succeeded is by monitoring key early players in apoptosis called caspases, a family of usually quiescent enzymes found inside every mammalian cell. activated by various biochemical cues from within or outside of the cell, caspases commence a cascade of molecular steps that steer the cell to a clean, quiet, ...

Local Heart Doctors First in Nation to Announce Active Investigation of Red Wine (Resveratrol) Pills, Issue Consumer Precautions

...cule. Resveratrol and other small molecules found in red wine can enter living cells and influence genetic machinery. One widely studied gene pathway, activated by resveratrol, is the Sirtuin1 gene, known as a survival gene. The current idea is to develop pills that will mimic the effects of a calorie-restrict...

Post-transplant combo can replace toxic immune-suppressing drugs in monkeys

...le is that we primates have more exposure to infections that require us to develop immunological memory," he says. "Memory cells are quicker to become activated and don't need costimulation as much, so blocking costimulation doesn't slow them down." By themselves, neither costimulation blockers (in this cas...

CU-Boulder study shows brain's immune system may cause chronic seizures

...when a severe brain injury has occurred. "When there has been serious damage to the brain, such as a head injury or infection, the immune system is activated and tries to counteract the damage and repair it," Barth said. "These glial cells migrate to the damaged area and release chemicals called cytokines t...

Microscopic 'beads' could help create 'designer' immune cells that ignore transplanted organs

...works through inhibitory receptors, ILT2, ILT3 and ILT4, on dendritic cells, triggering a signaling pathway in which several suppressive molecules get activated to help protect the transplanted organ or tissue. Human leukocyte antigen G, or HLA-G, actually is a member of a gene family called major histocompati...

Study in Nature: MicroRNAs hold promise for treating diseases in blood vessels

...to functioning muscle cells. miR-143 was found to block the expression of factors that promote proliferation by VSMC precursors. Surprisingly, miR-145 activated the expression of myocardin, which maintains VSMC in their mature form over their high-growth form. In a mouse model, expression of miR-143 and mi...

Cell Pathway May Be Key to Lung Cancer's Spread

...ncer Center, said that the report "for the first time demonstrates that lung cancer acquires the molecular traits necessary to metastasize early on by activated WNT/TCF signaling." The team of eight researchers used bioinformatics -- the highly complex computer analysis of genetic information -- to study lu...

Gene's novel role may provide key to treating liver and neurodegenerative diseases

...nimal, or microorganism) and produced by biotechnology methods. Curious about FAIM's role in immune cells, particularly its increased expression in activated B cells, key effectors of the human immune system responsible for fighting viruses and other pathogens that invade the body, the two scientists began ...

New Drug Could Work Against Leukemia

...n't receive the antibody. The researchers found that 7G3 blocked a signaling pathway in tumor cells, impaired migration of AML-LSCs to bone marrow and activated the immune system to destroy AML-LSCs. The findings, published in the July 2 issue of the journal Cell Stem Cell , hold promise for future cancer ...

Newly appreciated membrane estrogen receptor important therapeutic target for breast cancer

... because it provides a way for invading cells to gain hold once they metastasize to tissues distant to the primary breast cancer. This happens because activated integrin 51 can convert soluble plasma protein fibronectin into an insoluble cage. The breast cancer cells can use this to adapt to a ...

Atlantic Pharmaceuticals, Inc. Announces Completion of Successful Pre-IND Meeting with FDA for Abuse Deterrent Narcotic

...he drug. Once a drug is loaded into Smart/Script(TM) however, it is non-extractable in common injectable solutions, non-crushable and is released when activated in the gastrointestinal system. Anthony Soscia, President of Atlantic, stated, "We appreciate the comprehensive feedback we received from our pre...

Cancer Patients Use New Guided Imagery CD to Help Boost Healthy Immune Functioning

...regulate the body's defenses against cancer. Patients randomly assigned to the relaxation and guided imagery group had significantly higher numbers of activated T-cells, Natural Killer cells and LAK cells than patients who received standard care. It has long been known that guided imagery can improve coping an...

Platelet Rich Plasma Therapy (PRP) Accelerates Healing of Joint Injuries, Osteoarthritis Pain

...ain. When in their resting state, platelets look like sea sponges and when activated form branches. Platelets were initially known to be responsible for blood clotting. In the last 20 years physicians have learned that when activated in the body, platelets release healing proteins called growth factors. ...
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