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Lung cancer cells activate inflammation to induce metastasis

A research team from the University of California, San Diego School of Medicine has identified a protein produced by cancerous lung epithelial cells that enhances metastasis by stimulating the activity of inflammatory cells. Their findings, to be published in the January 1 issue of the journal Na...

Money, Praise Similarly Activate Brain's Reward Center

Imaging shows striatum lights up, offering neural explanation for everyday behaviors THURSDAY, April 24 (HealthDay News) -- Your brain may be telling you to be nice because it will pay off -- financially or socially, says a new study. Japanese researchers using functional magnetic ...

Video games activate reward regions of brain in men more than women, Stanford study finds

STANFORD, Calif. - Allan Reiss, MD, and his colleagues have a pretty good idea why your husband or boyfriend can't put down the Halo 3. In a first-of-its-kind imaging study, the Stanford University School of Medicine researchers have shown that the part of the brain that generates rewarding feelin...

Food peptides activate bitter taste receptors

PHILADELPHIA (January 22, 2008) -- Researchers from the Monell Center and Tokyo University of Agriculture have used a novel molecular method to identify chemical compounds from common foods that activate human bitter taste receptors. The findings, published in the journal Biochemical and Bioph...

Smokers' Brain Centers Activate During Nicotine Cravings

Finding could lead to better smoking-cessation aids WEDNESDAY, Dec. 19 (HealthDay News) -- Specific areas of the brain show increased activation in smokers who are deprived of nicotine, says a University of Pennsylvania study. The finding may boost understanding of cigarette cravings, a key ...

Belief, disbelief and uncertainty activate distinct brain regions

The capacity of the human mind to believe or disbelieve a statement is a powerful force for controlling both behavior and emotion, but the basis of these states in the brain is not yet understood. A new study found that belief, disbelief and uncertainty activate distinct regions of the brain, with...

YMCA's Activate America(R) Motivates More Than 1.3 Million People to Take 8 Billion Steps Toward a Healthier Lifestyle During 'America On the Move Week with the YMCA'

More Than 1,500 YMCAs Get Their Communities Moving During Week-Long Event; YMCAs Aim to Keep Communities Active Year-Round WASHINGTON, Oct. 18 /PRNewswire/ -- YMCAs nationwide want the 8 billion small steps logged during "America On the Move Week with the YMCA" to inspire a giant lea...

Scientists Activate New Cancer Drug Using Light and Oxygen

Researchers at the Ontario Cancer Institute at Princess Margaret Hospital have successfully proven that cancer cells alone can be killed by a new cancer drug that is triggered by a laser light, a process known as photodynamic therapy (PDT). In a study published today in the Proceedings of...

Bellicum Pharmaceuticals Announces Initiation of Phase I/II Clinical Trial of Novel Vaccine for Patients With Advanced Prostate Cancer

...ing regulation technology underlying BP-GMAX-CD1 were licensed from ARIAD Pharmaceuticals, Inc. AP1903 is designed to bring together two proteins and activate them. In the case of BP-GMAX-CD1, administration of AP1903 to patients leads to controlled activation of the ARGENT-regulated protein iCD40. AP1903 w...

Micromet, Inc. Reports Second Quarter 2009 Financial Results

...ith its proprietary BiTE(R) antibody platform, as well as conventional monoclonal antibodies. BiTE antibodies represent a new class of antibodies that activate the T cells of a patient's immune system to eliminate cancer cells. Five of Micromet's antibodies are currently in clinical trials. Its BiTE antibody ...

YMCA of the USA Announces 16 Communities Selected for Statewide Policy Change Initiative to Reverse the Childhood Obesity Epidemic

... today. These communities will be part of Y-USA's activate America(R): Pioneering Healthier Communities (PHC...o www.ymca.net/activateamerica About activate America(R): Pioneering Healthier Communities ...ioneering Healthier Communities (PHC) is a part of activate America, the YMCA's response to the nation's growi...

Nanotechnology Transforms Pain Relief

...lied excessively. MyOmega(R) deters excessive application by avoiding the use of Methyl Salicylate and using a gradual release philosophy to naturally activate potent pain relievers throughout the day. The secret behind MyOmega(R)'s extended release is a nanosphere-encapsulated cooling system . Each...

New microchip technology performs 1,000 chemical reactions at once

...re performed using in situ click chemistry, a technique often used to identify potential drug molecules that bind tightly to protein enzymes to either activate or inhibit an effect in a cell, and were analyzed using mass spectrometry. While traditionally only a few chemical reactions could be produced...

UF scientists program blood stem cells to become vision cells

...o the patient, you would give the drugs to their cells. Take the cells out, activate certain chemical pathways, and put the cells back into the patient." In ...icine at UF's McKnight Brain Institute. "As we proceeded, we found we could activate the stem cells by mimicking the body's natural signaling channels with chem...

Food additive may one day help control blood lipids and reduce disease risk

...escribe fibrate drugs to lower triglycerides and elevate good cholesterol in the blood, those drugs work by activating PPAR-alpha. Although fibrates activate the protein, no one previously had identified any naturally occurring substance that could perform that task. Reporting in the Aug. 7 issue of the jou...

Resvera Health Rx Launches All-Natural Resveratrol-Based Supplement with Anti-Aging and Disease-Fighting Properties

...e powerful antioxidants found in Resveratrol along with the heart-healthy benefits of Vitamin D3. Just one or two daily doses of Resvera Health Rx may activate the body's natural defense system against many diseases, including cancer, heart disease, diabetes, obesity, high blood pressure, Alzheimer's and oste...

Famous Names Get Single Neurons Fired Up

...ead her name, your Oprah neuron will probably rev up. An international team of researchers has found that single neurons in the brain's hippocampus activate when people recognize a photo or name, even if the image or name is distorted or presented in less than perfect fashion. "Different pictures of Mar...

Scientists discover key event in prostate cancer progression

...d other tissues. Male sex hormones androgens bind with these receptors to activate genes that control cell growth. The researchers show that in androgen-in...otein associated with that gene enabled androgen receptors to bind with and activate the gene in hormone-independent prostate cancer. Finally, they show that ...

RadioShack Partners With Seven-Time Tour de France Winner Lance Armstrong to Form New Cycling Team in 2010

...dies the spirit of mobility, connectivity and philanthropy - really allows us to accelerate our brand's evolution." RadioShack also plans to activate their 35,000 employees and almost 6,000 stores across the country to raise awareness and funding for the fight against cancer through the Lance Armstr...

Critical link in cell death pathway revealed

...ent of these cell surface proteins is FAS, but curiously it does not always activate apoptosis the same way, Professor Strasser said. "One of the things that's ...al journal Nature . For death to occur in type II cells, caspase-8 must activate the death-promoting protein called BID. Without this activation of BID the ...

Healing Depression The Mind-Body Way Aims to 'Depression-Proof' Your Life

...ervous system is the best pharmacy on earth, authors Nancy Liebler, Ph.D., and Sandra Moss, M.S.P.H., urge that holistic solutions must be utilized to activate the mind-body's ability to heal itself. "There is no one-size-fits-all cure for depression," note the authors. "You have to address each cas...

Stopping harmful oral bacteria in its path is goal for Case Western Reserve researcher

... receptors on the host epithelial and endothelial cells that promote the binding of the oral bacteria. "In some way, the receptors on the host cell activate a signal that puts into action a cascade of processes that allow the bacteria to penetrate the epithelial and endothelial linings and then colonize," ...

Kaiser Permanente Survey Shows Seniors Embrace Internet to Manage Their Health

...cords anywhere. My Health Manager is a free service available to all Kaiser Permanente members. Members can visit kp.org/register to sign up to activate and access their personal health records. About Kaiser Permanente Kaiser Permanente is committed to helping shape the future of health ...

Motion analysis helps soccer players get their kicks

...f the hip abductor and the knee position, could be a factor in the increased ACL injuries seen in female soccer players. Female players also do not activate their medial quad muscles in their standing leg, one way male players could be protecting their patellofemoral joint from injury. The hip flexor activ...

Abatement Technologies Sees Strong Demand as Hospitals Prepare for Stage 6 Flu Pandemic

...idal UV Modules from healthcare facilities as they activate their emergency pandemic preparedness plans. ...idal UV Modules from healthcare facilities as they activate their emergency pandemic preparedness plans. A...tates that, "All countries should immediately activate their pandemic preparedness plans." ...

Study in Nature: MicroRNAs hold promise for treating diseases in blood vessels

...l wall thickening, but that theory will need to be confirmed by further studies. In addition, Rochester investigators found that myocardin and SRF activate genes that may influence the rate at which the brain can remove amyloid beta, the toxic protein that builds up in blood vessels in the brains of patie...

C-Section Stress Could Alter Baby's Immune Cells

...s the degree of DNA-methylation in the white blood cells, which are a key part of the immune system. In DNA-methylation, DNA is chemically modified to activate or turn off genes in response to changes in the external environment. The 16 infants born by C-section had higher DNA-methylation rates immediately...

Fate Therapeutics Granted Exclusive License By The Regents of the University of California to Stem Cell Modulators for Osteo-Regeneration

...Dr. Parhami. "Our work has uncovered novel strategies and mechanisms for lineage-specific differentiation to an osteoblast phenotype. The ability to activate specific populations of stem cells in the body to promote bone regeneration may have many orthopedic clinical applications." Dr. Parhami contin...

Risk of cancer

...duced by lifestyle changes. Colorectal cancer is the third most common cancer worldwide and a major cause of cancer mortality. Mutation mechanisms activate pathways regulating cancer The variant that increases the risk of colorectal cancer was found to be located in a regulatory region, where it chang...

Video: New Online Film Introduces Longevinex Advantage(TM) -- The First Resveratrol-Based Dietary Supplement to Address Both Cellular and Connective Tissue Aging

... quercetin, rice bran IP6, ferulic acid, lutein, grape seed, green tea and cocoa bean extracts which have been demonstrated to work synergistically to activate more longevity genes than plain resveratrol. The film, produced by Michael Gonzales & Associates, is available for viewing online at www.lon...

Smoking May Trigger Brain Damage

...nhealthy cells, but when provoked by NNK, they attack healthy brain cells, the researchers added. "Our findings prove that tobacco compound NNK can activate microglia significantly, which subsequently harms the nerve cells," lead researcher Dr. Anirban Basu said in a news release. The study appears in t...

New research discovers link between smoking and brain damage

...tart to attack healthy brain cells rather than the unhealthy cells they are supposed to attack. "Our findings prove that tobacco compound NNK can activate microglia significantly which subsequently harms the nerve cells," said Basu. While other harmful side effects of smoking, such as lung disease, u...

Statins can protect against Alzheimer's disease, according to new study

...mor necrosis factor has a strong beneficial effect on nerve cells and can protect nerve cells against death. A widely prescribed drug like statins can activate this protective pathway revealing strong beneficial effect. ...

Heart Attacks Less Often Fatal Today

... Myerson and Jacobs agree that public education is the best way to reduce that delay. "When someone has chest pain or chest discomfort, they need to activate the emergency response system as quickly as possible," Myerson said. "We need to educate people on the impending signs of heart attack. "It might n...

Deploying the Power of Music to Save Lives West Africa's Most Beloved Singer Raises His Voice to End Malaria

...ets kicking off in late June. On June 20, the Youssou Ndour Foundation and Malaria No More are launching "Surround Sound: Senegal", a campaign to activate key sectors of society -- including entertainment, sport, faith, local business and government -- to encourage people to use mosquito nets and seek tr...

Phase 1 Study Initiated with Micromet Anti-GM-CS Human Antibody MT203

...ith its proprietary BiTE(R) antibody platform, as well as conventional monoclonal antibodies. BiTE antibodies represent a new class of antibodies that activate the T cells of a patient's immune system to eliminate cancer cells. Five of Micromet's antibodies are currently in clinical trials. Its BiTE antibody ...

2009 ISSSEEM Conference to Have Deepak Chopra Discuss Bridging Science and Spirit

...verberations. Sound vibrations resonate in the heart, engendering sensations, emotions, and visions, while different frequencies and harmonic patterns activate the chakras and nervous system in different ways. The heart is the body's most dynamic field integrator of the subtle energies of the life force. This...

QLT announces 12-month results from Novartis sponsored MONT BLANC study evaluating standard-fluence Visudyne(R) combination therapy

...ocedure involving the intravenous administration of the drug into the patient's arm. A non-thermal laser light is then shone into the patient's eye to activate the drug. This produces a reaction that closes the abnormal leaky vessels, resulting in a stabilization of the corresponding vision loss. Visudyne i...

LSUHSC research finds single gene controls growth of some cancers

... changes in response to excessive levels of free radicals) within the EBV-infected cells. Varying levels of oxidative stress change EBNA1's ability to activate EBV genes responsible for indiscriminate tumor cell growth. "We have shown that in vitro, existing therapeutics such as Vitamin K that can change ox...

Frequent Snoring in Pregnancy Could Signal Blood Sugar Trouble

...ng may be a sign of poor air flow and diminished oxygenation during sleep that can cause a cascade of events in your body," Facco explained. "This may activate your sympathetic nervous system, so your blood pressure rises at night. This can also provoke inflammatory and metabolic changes, increasing the risk ...
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