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Promising pre-clinical results support advance to clinical study for third
combination chemotherapy from Celator based on the company's proprietary CombiPlex(TM) technology platform.
PRINCETON, N.J., Oct. 26 /PRNewswire/ -- Celator Pharmaceuticals today
announced positive re...
...hed in Cell Stem Cell suggests that reducing the ratio of these cells within tumors may dramatically impr...hemotherapeutic agents significantly decreases the ratio of cancer stem cells found in colon and breast tum...hemotherapy alone was demonstrated to increase the ratio of tumorigenic stem cells found in colon and breas...
...e formulated into small (0.3 micron), neutral liposomes that enable penetration of the biofilm and are highly efficient, with a very low lipid-to-drug ratio (0.65). ARIKACE can be delivered through nebulization, which enables the small aerosol droplet size (1 to 5 microns) to facilitate more effective d...
...debt and return $60 million to shareholders through share repurchases and a 12% increase in the 2009 quarterly dividend. The Company's debt to capital ratio was reduced to 28.6% at June 30, 2009 from 34.6% at December 31, 2008. The Company has not experienced any problem in placing its short-term debt in ...
...1 in 4 pre-teen cases of anorexia are male. There are thousands of males with eating disorders in our society. Historically, it was thought that the ratio of boys to girls with eating disorders was 1:10, but more recent research indicates that it may be closer to 1:3. "Over the past 10 years, the ma...
....9 months for patients treated with docetaxel alone -- a 6.9 month observed survival advantage for the OGX-011 arm. Furthermore, the unadjusted hazard ratio (HR), a measure used to compare the death rates between treatment groups, was 0.61, representing a 39% lower rate of death for patients treated with O...
...ery four weeks plus daily ribavirin in treatment-naive patients with genotypes 2 and 3 chronic hepatitis C. 391 patients were randomized in a 4:4:4:3 ratio into four treatment groups, including three that will receive albinterferon alfa-2b administered once every four weeks (900 mcg, 1200 mcg or 1500 mcg)...
...to brain tumors while minimizing radiation exposure to healthy organs, including the thyroid, are very encouraging," said Dr. Shen. "With a mean dose ratio showing 300-fold greater delivery of radiation to the tumor as compared to other organs, Cotara represents a potentially valuable new therapy for GBM ...
...l investment in new instrumentation. The CCHAR probe offers high-aspect ratio imaging capability and is designed for materials science, metrology and lif...e science applications. It offers stability and durability in a high-aspect ratio probe designed for difficult to resolve scanning operations such as deep-tr...
...ive control (phenelzine) and a comparator drug (selegiline). The study results were based on the Tyramine Sensitivity Factor (TSF), which measures the ratio of tyramine pressor dose before (baseline) and after MAO inhibitor administration. Geometric mean TSFs of all doses of rasagiline were substantially l...
...opulation with chronic HCV infection, and to compare it with two indices that employ nonspecific biomarkers, aspartate aminotranaminase (AST)-platelet ratio index (APRI) and Fibrosis-4 (FIB-4). Three hundred and ninety one patients with chronic HCV infection undergoing liver biopsy were enrolled from the L...
...omal encapsulation maintains the desired 5:1 molar ratio of cytarabine:daunorubicin in CPX-351, extends bio...firmed that CPX-351 maintained the fixed 5:1 molar ratio of cytarabine:daunorubicin for prolonged periods o... allowing the release of the synergistic 5:1 molar ratio of the active agents intracellularly, and demonstr...
... cancer, patients in the PROSTVAC(TM) group had a significantly longer median overall survival by 8.5 months compared to the control group. The hazard ratio estimate for overall survival from the study is 0.56 (95% CI 0.37-0.85). The statistical significance in the final data set is (p=0.006). ...
...nt improvement in PFS, was not met, the docetaxel plus AT-101 arm demonstrated a positive trend in OS, as reflected in the Kaplan-Meier curves (hazard ratio 0.82). This group also demonstrated a 33 percent increase in median survival and a 34 percent increase in 6-month survival compared to the docetaxel ...
... survival advantage for the OGX-011 arm. 2) The unadjusted hazard ratio (HR), a measure used to compare the death rates between treatment g... is a clear separation of the survival curves," said Blumenstein. "A hazard ratio of 0.61 indicates a distinct difference in survival rates and fully justifi...
...es. For CABG patients, the primary endpoint is the ratio of obstructed/occluded grafts (defined here as (gr...r CABG patients, the overall obstruction/occlusion ratio at 15 months was 16 percent, with six percent of g... On a per patient basis, the obstruction/occlusion ratio was 27 percent, with nine percent of patients havi...
...ith OGX-011 plus docetaxel in a randomized Phase 2 trial was 27.5 months compared to 16.9 months for patients treated with docetaxel alone. The hazard ratio (HR), a measure used to determine the difference in survival between treatment groups, was 0.60, representing a 40% reduction in the rate of death for...
...Agency. The study is 90 percent powered to show a 33 percent reduction in risk in overall survival for the treatment arm compared to BSC alone (hazard ratio = 0.67) (p < 0.05). Our Phase 2 study in resistant or refractory disease or patients who relapsed within 180 days of first-line platinum therapy, d...
...ichment demonstrated to date varies from 3 to 100-fold, which will contribute to Transgenomic's target of achieving a 1/10,000 mutant to normal allele ratio detection in a routine, cost-effective and high throughput protocol. This level of detection will allow straightforward tumor analysis via surrogate t...
... the nonwoven product for different applications. The polymer allows the benefit of altering properties such as the shape of the nonwoven, core sheath ratio and the weight and structure of the nonwovens. The polymer is also highly compatible with polypropylene. This is of value particularly during the maki...
Determining the Signal-to-Noise Ratio and Optimal Photomultiplier gain setting in the GenePix 4000B
Siobhan Pickett, M.S., Sean Carriedo, Ph.D. and Chang Wang, Ph.D. Axon Instruments, Inc. 3280 Whipple Road, Union City, CA 94587 Last updated: September 13, 2001 Introduction An important criterion for comparing the perf...OncoGenex Reports Second Quarter 2009 Financial Results
...9 months for patients treated with docetaxel alone -- a 6.9 month observed survival advantage for the OGX-011 arm. The unadjusted hazard ratio (HR), a measure used to compare the death rates between treatment groups, was 0.61, representing a 39% lower rate of death for patients ......hed in Cell Stem Cell suggests that reducing the ratio of these cells within tumors may dramatically impr...hemotherapeutic agents significantly decreases the ratio of cancer stem cells found in colon and breast tum...hemotherapy alone was demonstrated to increase the ratio of tumorigenic stem cells found in colon and breas...
...e formulated into small (0.3 micron), neutral liposomes that enable penetration of the biofilm and are highly efficient, with a very low lipid-to-drug ratio (0.65). ARIKACE can be delivered through nebulization, which enables the small aerosol droplet size (1 to 5 microns) to facilitate more effective d...
Sanofi-aventis Announces Second Quarter 2009 Results
... 13.6%, or of 7.0% at constant exchange rates. The ratio of cost of sales to net sales improved by 1.2 poin...onstant exchange rates, to euro 1,895 million. The ratio of selling and general expenses to net sales fell ... At constant exchange rates, growth was 16.0%. The ratio of operating income - current to net sales improve...Zimmer Launches New Medical Education and BioSkills Training Program
...dividual surgeon's experience level, providing in-depth knowledge on products and procedures. Zimmer Institute courses have a high faculty-to-student ratio and incorporate new technologies, promoting greater interaction with faculty trainers and participant collaboration. Courses are offered at many regio......debt and return $60 million to shareholders through share repurchases and a 12% increase in the 2009 quarterly dividend. The Company's debt to capital ratio was reduced to 28.6% at June 30, 2009 from 34.6% at December 31, 2008. The Company has not experienced any problem in placing its short-term debt in ...
...1 in 4 pre-teen cases of anorexia are male. There are thousands of males with eating disorders in our society. Historically, it was thought that the ratio of boys to girls with eating disorders was 1:10, but more recent research indicates that it may be closer to 1:3. "Over the past 10 years, the ma...
Schering-Plough Announces Phase II and III Data for Corifollitropin Alfa
...SURE The ENSURE trial is a multinational (Europe/Asia), double-blind, randomized trial; 396 patients weighing 60 kg or less were randomized in a 2:1 ratio to treatment with either a single dose of 100 mcg corifollitropin alfa or daily 150 IU rFSH (follitropin beta) followed by daily follitropin beta (max...Stanford researchers find a quicker, cheaper way to sort isotopes
...e chemistry department. The tool can calculate the ratio of isotopes in a sample by simply "counting the co...l now, the analysis has been done using an isotope ratio mass spectrometer, which works by giving individua...be used with minimal training. Existing isotope ratio mass spectrometers can weigh as much as 1500 pound...Kewaunee Scientific Reports Record Results Net Earnings for Year Increase 36%, Sales Increase 16%
...rrowings and capital lease obligations were $6.1 million at year-end, as compared to $5.0 million at the end of the prior year, and the debt-to-equity ratio was .23-to-1 at year-end, as compared to .19-to-1 at the end of the prior year. "This past year was a rewarding, yet challenging year," said Will.......9 months for patients treated with docetaxel alone -- a 6.9 month observed survival advantage for the OGX-011 arm. Furthermore, the unadjusted hazard ratio (HR), a measure used to compare the death rates between treatment groups, was 0.61, representing a 39% lower rate of death for patients treated with O...
...ery four weeks plus daily ribavirin in treatment-naive patients with genotypes 2 and 3 chronic hepatitis C. 391 patients were randomized in a 4:4:4:3 ratio into four treatment groups, including three that will receive albinterferon alfa-2b administered once every four weeks (900 mcg, 1200 mcg or 1500 mcg)...
...to brain tumors while minimizing radiation exposure to healthy organs, including the thyroid, are very encouraging," said Dr. Shen. "With a mean dose ratio showing 300-fold greater delivery of radiation to the tumor as compared to other organs, Cotara represents a potentially valuable new therapy for GBM ...
...l investment in new instrumentation. The CCHAR probe offers high-aspect ratio imaging capability and is designed for materials science, metrology and lif...e science applications. It offers stability and durability in a high-aspect ratio probe designed for difficult to resolve scanning operations such as deep-tr...
...ive control (phenelzine) and a comparator drug (selegiline). The study results were based on the Tyramine Sensitivity Factor (TSF), which measures the ratio of tyramine pressor dose before (baseline) and after MAO inhibitor administration. Geometric mean TSFs of all doses of rasagiline were substantially l...
...opulation with chronic HCV infection, and to compare it with two indices that employ nonspecific biomarkers, aspartate aminotranaminase (AST)-platelet ratio index (APRI) and Fibrosis-4 (FIB-4). Three hundred and ninety one patients with chronic HCV infection undergoing liver biopsy were enrolled from the L...
...omal encapsulation maintains the desired 5:1 molar ratio of cytarabine:daunorubicin in CPX-351, extends bio...firmed that CPX-351 maintained the fixed 5:1 molar ratio of cytarabine:daunorubicin for prolonged periods o... allowing the release of the synergistic 5:1 molar ratio of the active agents intracellularly, and demonstr...
... cancer, patients in the PROSTVAC(TM) group had a significantly longer median overall survival by 8.5 months compared to the control group. The hazard ratio estimate for overall survival from the study is 0.56 (95% CI 0.37-0.85). The statistical significance in the final data set is (p=0.006). ...
...nt improvement in PFS, was not met, the docetaxel plus AT-101 arm demonstrated a positive trend in OS, as reflected in the Kaplan-Meier curves (hazard ratio 0.82). This group also demonstrated a 33 percent increase in median survival and a 34 percent increase in 6-month survival compared to the docetaxel ...
... survival advantage for the OGX-011 arm. 2) The unadjusted hazard ratio (HR), a measure used to compare the death rates between treatment g... is a clear separation of the survival curves," said Blumenstein. "A hazard ratio of 0.61 indicates a distinct difference in survival rates and fully justifi...
AFFiRiS AG: Atherosclerosis Vaccine Development Receives EU Support
...fer protein (CETP). By transferring cholesteryl ester from HDLc to LDLc and VLDLc, this protein reduces "good" HDL and has a detrimental impact on the ratio of LDLc to HDLc. In the future, our vaccine will reduce the activity of this protein and shift the balance of HDLc and LDLc in the blood back in favou......es. For CABG patients, the primary endpoint is the ratio of obstructed/occluded grafts (defined here as (gr...r CABG patients, the overall obstruction/occlusion ratio at 15 months was 16 percent, with six percent of g... On a per patient basis, the obstruction/occlusion ratio was 27 percent, with nine percent of patients havi...
China Biologic Products Announces Strong First Quarter 2009 Results
... Financial Condition As of March 31, 2009, the Company had $34.0 million in cash, approximately $2.2 million in working capital and a current ratio of 1.0. Shareholder's equity at the end of the first quarter of 2009 was $39.9 million, compared to $37.2 million at the end of 2008. The Company gen......ith OGX-011 plus docetaxel in a randomized Phase 2 trial was 27.5 months compared to 16.9 months for patients treated with docetaxel alone. The hazard ratio (HR), a measure used to determine the difference in survival between treatment groups, was 0.60, representing a 40% reduction in the rate of death for...
ChanTest Awarded $4.8 Million Through the Ohio Third Frontier Research and Commercialization Program
...aceutical customers create better, safer drugs. The 2006 grant added four additional jobs for each job it provided. We expect to greatly increase this ratio and the total number of new jobs in the next three years." About ChanTest - The Ion Channel/GPCR Company ( www.chantest.com ) The le......Agency. The study is 90 percent powered to show a 33 percent reduction in risk in overall survival for the treatment arm compared to BSC alone (hazard ratio = 0.67) (p < 0.05). Our Phase 2 study in resistant or refractory disease or patients who relapsed within 180 days of first-line platinum therapy, d...
Covance Reports First Quarter Revenue of $441M and EPS of $0.63; Updates Full Year Financial Targets
...vious record high). "On the commercial front, adjusted net orders in the first quarter were $589 million, representing an adjusted book-to-bill ratio of 1.34 to 1. Central laboratory and clinical development services each delivered record adjusted net orders in the quarter, leading to a trailing twe...PAREXEL Reports Third Quarter Fiscal Year 2009 Financial Results
... - Diluted earnings per share of $0.25 - Net quarterly book-to-bill ratio equates to 1.25 BOSTON, April 27 /PRNewswire-FirstCall/ -- PAREXEL Int... impact from foreign exchange rates of $37.4 million. The net book-to-bill ratio was 1.25 in the quarter (defined as gross new business less cancellations d...China Yongxin Pharmaceuticals, Inc. Announces 2008 Fourth Quarter and Full Year Financial Results
...portunity, while creating further value for our shareholders," concluded Mr. Liu. Balance Sheet and Cash Flow The Company had a current ratio of 1.8 to 1 and $0.6 million in cash and cash equivalents on December 31, 2008. Stockholders' equity was $13.6 million, with working capital of $10.2 ......ichment demonstrated to date varies from 3 to 100-fold, which will contribute to Transgenomic's target of achieving a 1/10,000 mutant to normal allele ratio detection in a routine, cost-effective and high throughput protocol. This level of detection will allow straightforward tumor analysis via surrogate t...
China Biologic Products Announces Strong 2008 Results
... Financial Condition As of December 31, 2008, the Company had $8.8 million in cash, approximately $6.3 million in working capital and a current ratio of 1.3. Shareholder's equity at 2008 year-end was $37.8 million, compared to $22.4 million at the end of 2007. The Company generated $20.0 million in ...... the nonwoven product for different applications. The polymer allows the benefit of altering properties such as the shape of the nonwoven, core sheath ratio and the weight and structure of the nonwovens. The polymer is also highly compatible with polypropylene. This is of value particularly during the maki...
MIT: 'Alarming' use of energy in modern manufacturing methods
...he inherent inefficiency of current solar panel manufacturing methods could drastically reduce the technology's lifecycle energy balance that is, the ratio of the energy the panel would produce over its useful lifetime to the energy required to manufacture it. The new study is just "the first step in d...China Bio Energy Reports Fourth Quarter and Record 2008 Financial Results
...d in October 2008), compared to $1.4 million on December 31, 2007. The Company had working capital of $67.5 million on December 31, 2008 and a current ratio of 7.3 to 1. Inventories were $22.3 million and the accounts receivable balance was $8.2 million on December 31, 2008, compared to $12.0 and $0.3 mill...Extraordinary General Meetings Statement -- XTL Also Announces Board and Management Changes
...of the shareholders, the Company will take the necessary steps to implement and effect the reverse split, increase in registered share capital and the ratio change of the Company's ADRs. David Grossman, the Company's CEO, commented, "On behalf of XTL's new management and Board, we are very excited to...Atherotech to Exhibit the VAP(R) Cholesterol Test at ACC.09 in Orlando
... Cardio-diagnostic company adds new apoAI measurement and apoB/apoAI ratio to advanced lipid profile for heart disease risk stratification BIRMIN...cluding INTERHEART and the AMORIS trials, have clearly shown the apoB/apoAI ratio to be superior to all other cardiovascular disease risk marker ratios. ...Atherotech Announces Addition of ApoAI Heart Disease, Diabetes Risk Marker to VAP(R) Test
... ApoAI and apoB/apoAI ratio now available with VAP Cholesterol Test at no addi... Cholesterol Test at no added cost. "The new ratio gives physicians and their patients a single, easy...RIS trials, have clearly shown that the apoB/apoAI ratio is superior to all other cardiovascular disease ri...ERT Reports Fourth Quarter and Full Year 2008 Results
... very pleased that we could increase our gross margin to 57.3%. We were also pleased with the $45.1 million in new bookings and our gross book-to-bill ratio of 1.5, both up from the third quarter. As a whole, 2008 was very strong. We recorded record revenues, bookings and backlog. Our 2008 operating inc...Other TagsABCABCcelebratecelebrateNSANSANSAdoubledstressesportportportportportportportportlagsOther Contentstreatmenttreatmenttreatmenttreatmenttreatmenttreatmenttreatmenttreatmenttreatmenttreatmentempiricalempiricalempiricalempiricalisolatedisolatedisolatedisolatedisolatedisolatedisolatedisolatedisolatedscanscanscanscanscanscanscanextracorporealextracorporealliftliftliftliftliftlift
(Date:11/23/2009)...research presents strong evidence that the "synerg...or traffic-related pollution and indoor endotoxin ...he other exposure alone. , Environmental healt...College of Medicine have shown that children expos...s and indoor endotoxin during early life are six t...
(Date:11/23/2009)...by the Wildlife Conservation Society says that wes...he Republic of Congopart of the "mother lode" of m...becoming increasingly threatened by growing humans...protection of the swamp forests adjacent to the so...ecent surveys confirmed that high densities of the...
(Date:11/23/2009)... The only swine vaccine available for the H1N1 vir...d with the virus. The vaccination marks the first ...ed with the pandemic flu., Iowa State University...oped the vaccine this summer and has been shipping...as and Illinois for several weeks., The latest v...
Breaking Biology News(10 mins):Exposure to both traffic, indoor pollutants puts some kids at higher risk for asthma later 2A year after discovery, Congo's 'mother lode' of gorillas remains vulnerable 2Iowa State researcher produces, ships only H1N1 vaccine available for swine 2Congressmen Mike Ross and Kendrick Meek Introduce Bill to Protect Medicare Patients Who Require Medical Oxygen Therapy at Home 51965 1Congressmen Mike Ross and Kendrick Meek Introduce Bill to Protect Medicare Patients Who Require Medical Oxygen Therapy at Home 51965 2Congressmen Mike Ross and Kendrick Meek Introduce Bill to Protect Medicare Patients Who Require Medical Oxygen Therapy at Home 51965 3GSK to Announce Q2 Results July 22 2009 51962 1GoHealthInsurance Announces Appointment of Mike Owens as Senior Vice President 51959 1GoHealthInsurance Announces Appointment of Mike Owens as Senior Vice President 51959 2(Date:11/27/2009)...lus low-emission vehicles may reduce future diseas...v. 27 (HealthDay News) -- Encouraging city dweller...offer much greater public health benefits than inc...hers have found. , The study compared the proje...and transport scenarios for London, England, and D...
(Date:11/27/2009)... , SEATTLE, Nov. 27 Allrecipe...d-high Thanksgiving traffic numbers, with more tha..., providing a clear picture of what was served on ...Thanksgiving meal in 2009 weighed in at 2,225 calo...ear,s feast. According to the Allrecipes site, Sw...
(Date:11/27/2009)... Multi-purpose bilingual coloring books design...the business community to educate - inform parents...Safety issues to Dinosuars to ABC,S and a host of ...is, MO (PRWEB) November 27, 2009 -- Today’s ...to keep them busy any hour of the day, but one of ...
(Date:11/27/2009)... Three new interactive anatomy education apps ...s expand health sciences learning opportunities fo... Durham, NC (Vocus) November 27, 2009 -- Modality...), a division of Wolters Kluwer Health, today anno...ion apps on the App Store. Clemente’s Anatom...
(Date:11/26/2009)...ON, N.J., Nov. 27 The diabetes pop...er the next 25 years and annual medical spending o... from $113 billion today, according to a study pub...The National Changing Diabetes ® Program (NC...nalysis by a team from the University of Chicago. ...
Breaking Medicine News(10 mins):Health News:More Foot Power, Less Car Pollution Best for Health 2Health News:It's Black Friday - Time to Shop Off the Calories! Allrecipes Finds Average Thanksgiving Meal Weighed in at 2,225 Calories 2Health News:It's Black Friday - Time to Shop Off the Calories! Allrecipes Finds Average Thanksgiving Meal Weighed in at 2,225 Calories 3Health News:It's Black Friday - Time to Shop Off the Calories! Allrecipes Finds Average Thanksgiving Meal Weighed in at 2,225 Calories 4Health News:Really Big Coloring Books Debuts Bi-Lingual Spanish-English Line of Custom and Imprintable Coloring Books 2Health News:Clemente's Anatomy, Rohen's Photographic Anatomy, and Moore's Clinical Anatomy Customizable Apps Now Available on App Store 2Health News:Clemente's Anatomy, Rohen's Photographic Anatomy, and Moore's Clinical Anatomy Customizable Apps Now Available on App Store 3Health News:Clemente's Anatomy, Rohen's Photographic Anatomy, and Moore's Clinical Anatomy Customizable Apps Now Available on App Store 4Health News:Clemente's Anatomy, Rohen's Photographic Anatomy, and Moore's Clinical Anatomy Customizable Apps Now Available on App Store 5Health News:Diabetes Population to Double, Diabetes Costs to Nearly Triple, in 25 Years, New Study Shows 2Health News:Diabetes Population to Double, Diabetes Costs to Nearly Triple, in 25 Years, New Study Shows 3Health News:Diabetes Population to Double, Diabetes Costs to Nearly Triple, in 25 Years, New Study Shows 4[0] More Foot Power, Less Car Pollution Best for Health[0] It's Black Friday - Time to Shop Off the Calories! Allrecipes Finds Average Thanksgiving Meal Weighed in at 2,225 Calories[1] Really Big Coloring Books Debuts Bi-Lingual Spanish-English Line of Custom and Imprintable Coloring Books [0] Clemente's Anatomy, Rohen's Photographic Anatomy, and Moore's Clinical Anatomy Customizable Apps Now Available on App Store[1] Diabetes Population to Double, Diabetes Costs to Nearly Triple, in 25 Years, New Study Shows
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