load in Biological Technology

InterMune Reports Second Quarter 2009 Financial Results and Business Highlights

...n, in patients with HCV infection. Data from the first four dosage cohorts of the study demonstrated that the combination resulted in sustained viral load reductions over the dosing period in all cohorts. The combination was well tolerated over 14 days, with no treatment-related serious adverse events (...

Anadys Pharmaceuticals Receives FDA Clearance of Phase II Protocol to Study ANA598 in Combination With Interferon-Alpha and Ribavirin in HCV Patients

...vity and good tolerability. In a monotherapy study in naive genotype 1 patients, treatment with ANA598 for three days led to median declines in viral load ranging from 2.4 to 2.9 log10 in three separate dose groups. No patient at any dose level showed evidence of viral rebound while on ANA598, and there...

Anadys Pharmaceuticals Reports Second Quarter 2009 Financial Results and Program Highlights

...udy in HCV patients were reported at the EASL conference. The median viral load reduction over three days ranged from 2.4 to 2.9 log10 in the three dose gr...ng dosed. During the second quarter the Company reported evidence of viral load reduction in a majority of patients who received ANA773 at 1600 mg. Anadys...

PROTOMED SA Chooses HyperWorks to Simulate Implantable Medical Devices

...and to develop new and innovative implantable medical devices. PROTOMED engineers use CAE to predict physical responses of biological systems to known load conditions and will use HyperWorks to model medical devices for various applications, ranging from coronary stents to orthopedics implant. "We...

Three Rivers Announces Positive Results from Phase 3 DIRECT Trial of Once-Daily INFERGEN(R) with Ribavirin in Hepatitis C Virus Treatment Failures

...d-interferon plus ribavirin therapy. The best SVR rates were seen in: Patients achieving the greatest reduction in baseline viral load with peg-IFN/RBV therapy, especially in patients demonstrating > 1-log drop with initial therapy Patients with fibrosis scores of F0 to...

Phase 3 Cystic Fibrosis Trial Results Presented at European Conference

...n microbial growth for specific microorganisms between treatment groups, confirming that Bronchitol does not contribute to the bacterial load in the lung. Bronchitol has received Orphan Drug Designation and fast track status for cystic fibrosis from the U.S. Food and Drug Administrat...

Valeant Pharmaceuticals Reports Encouraging Final Results With Taribavirin Phase IIb Study

...enotype 1 patients were randomized with the following patient demographics: mean age 48.8 yrs, 61.1% male, 30% African-American or Latino, 80.7% viral load >=400,000 IU/mL and 82.1 kg mean weight. About Valeant Valeant Pharmaceuticals International (NYSE: VRX ) is a multinational special...

ImmunoVaccine Technologies Partners with FIT Biotech to advance a therapeutic HIV vaccine

...eed for effective HIV therapeutic vaccines. Therapeutic vaccination offers the most hope for HIV infected individuals because it maintains a low viral load and has the potential to modify the course of the infection and its progression towards the AIDS disease. ABOUT IVT ImmunoVaccine Technologi...

Veteran-Owned Biotech Startup Company Charges Health Agency (NYSDOH) with Blackballing its Initiatives

...oses of ozone administered to blood, as reported by researchers in Italy, Germany, Russia, and Japan. Such immune enhancement is said to lead to viral load reduction and to the normalization of liver enzyme levels. Dr. Sunnen added, "This study carried special significance for Egypt which is overwhelmed w...

Sangamo BioSciences Receives $100,000 Grand Challenges Explorations Grant for Innovative Global Health Research

...nfection ZFN-modified human immune cells survived and multiplied preferentially, leading to an increase in CD4+ T-cell counts and a reduction in viral load suggesting resistance to HIV ( Nat Biotechnol. 2008 Jul; 26(7):808-16). A Phase 1 clinical trial is ongoing at the University of Pennsylvania to ev...

Opus Environmental Introduces Innovative Food Waste Elimination Equipment to U.S. Food Industry

...umpsters, it saves the food-service operator money. Less weight goes into the dumpster, and the fewer times the waste hauler has to come and pick up a load -- saving the operator money. Opus will be displaying the product line at the 2009 NRA show at McCormick Place. One very hot topic at this year&rs...

InterMune Reports First Quarter 2009 Financial Results and Business Highlights

...dy were as follows: The combination resulted in sustained viral load reductions over the dosing period in all cohorts. Seventy percent (70%) of...w-dose groups, after only three days of dosing, the mean reduction in viral load levels was 0.6 log10 greater with combination treatment (-2.9) compared to ...

Real Time Genomics to Show SLIM Search(TM) Technology on Windows HPC Server 2008 at Bio-IT World Conference

...o the highest level," said Dr. Hugh Young Rienhoff, Jr., Founder, MyDaughtersDNA.org. "Whoever builds the interpretive platform for this massive data load will take the prize." About Real Time Genomics Real Time Genomics, Inc. ( http://www.realtimegenomics.com ) offers solutions for deep genomic...

Anadys Pharmaceuticals Reports First Quarter 2009 Financial Results and Highlights

... all dose levels. At 200 mg bid, the median viral load reduction was 2.4 log10 (range of 0.4 to 3.4); at ...12 genotype 1a patients who received ANA598, viral load was still declining at the end of the three days o... was a statistically significant decrease in viral load in the group dosed at 1600 mg compared to placebo,...

Idenix Pharmaceuticals Reports Data From Three Hepatitis C Development Programs at the 44th Annual Meeting of the European Association for the Study of the Liver

...elationship between nucleoside metabolite concentrations in serum and viral load reductions in this study. Trough serum nucleoside metabolite levels were lo...s a direct correlation between levels of NM and HCV RNA, with greater viral load reductions observed as the NM levels increased. Specifically, serum trough ...

Virco Lab, Inc. Enters Into Collaboration with SmartGene, Inc. Enhancing HIV Resistance Test Services for Laboratories and Physicians

... virologic failure or when treatment response is incomplete. RT is also recommended for all pregnant women before starting ARV treatment or when viral load is detectable while on therapy.(1) In cases of virologic failure, DHHS guidelines recommend consideration of not only the current resistance test...

Bridging the gap in nanoantennas

...tal evidence that the local antenna fields can be controlled by gap-loading. This opens the door for designing near-field patterns in the nanoscale by load manipulation, without the need to change antenna length, which could be highly valuable for the development of compact and integrated nanophotonic dev...

Impact Systems' Compliance-in-a-Box™ Video is Announced as "Be the Buzz of Bio" Contest Finalist

... EMC® Documentum® platform. The company has developed a proprietary suite of configuration management, content and metadata transfer, and bulk load software tools that provide significant time and cost savings for deployments, migrations and ongoing electronic content needs. Impact Systems special...

Aethlon Medical Announces Data Supported Strategy to Increase Hepatitis-C (HCV) Cure Rates

... over 20 HCV treatments indicates an average viral load reduction of 41% during each four-hour Hemopurifie...ment. In the studies, average pre-treatment viral load of 22,868,000 HCV virus copies/ml blood (cpm) was ...tinuous Hemopurifier(R) treatment can reduce viral load to low to undetectable levels, thus improving the ...

AcroMetrix Announces the Release of OptiQuant-S Hepatitis C Virus (HCV) Panel

...in the amount of virus (i.e. viral load) present in the patient when undergoing therapy for the disease. Physicians rely on the accuracy of the viral load test result provided by the laboratory to adjust and manage the drug regiment for the patient. "OptiQuant-S HCV represents our continued commitme...

Romark Announces Presentation of New Data for Controlled Release Nitazoxanide in Chronic Hepatitis C

...ference of the Asian Pacific Association for the Study of the Liver (APASL) Demonstrated Favorable Pharmacokinetics and Significant Reduction in Viral load TAMPA, Fla., Feb. 17 /PRNewswire/ -- Romark Laboratories, a privately held biopharmaceutical company, today announced results from international ...

VAP Cholesterol Test Helps In Search For New Heart Disease Drugs

...sociated with an increased risk of coronary artery disease. Those with the gene abnormality also had lower triglycerides both before and after the fat load and better lipid profiles overall. "This is a brilliant GWAS study that beautifully illustrates the value of advanced lipid profiling, direct LDL...

Beckman Coulter Announces Fourth Quarter and Full Year 2008 Results; Earnings Outlook Achieved on Strong Fundamentals

...s relating to testing for the hepatitis C virus (HCV). Under the agreement, we can develop, manufacture and sell a quantitative viral load HCV blood test for use on our molecular diagnostic instrument, which is in development. e) NexGen Acquisition - In November 2007, we acqu...

Sangamo BioSciences Reports Fourth Quarter and Full Year 2008 Financial Results

...een shown to lead to an increase in CD4 T-cell counts, a reduction in viral load and expansion of CCR5-modified T-cells that are resistant to the virus in a...n T-cells and the positive effects on HIV resistance and reduction in viral load in an animal model of HIV infection. Sangamo's ZFN technology rec...

While Most Companies and Industries Struggled in 2008, LifeModeler, Inc. Used Unique Products to Post Aggressive Business Gains in All Areas

...gth than being called upon to help NASA put men on Mars? LMI's software is integral to the space agency's determinations as to how large a weight load astronauts are able to handle under differing circumstances in a weightless environment. The company has worked with NASA for a few years and 2008 sa...

Sangamo BioSciences Initiates Phase 1 Trial of CCR5-ZFP Therapeutic to Treat HIV/AIDS

...nfection to lead to an increase in CD4+ T-cell counts, a reduction in viral load and expansion of CCR5-modified T-cells, suggesting resistance to HIV. ...ed numbers of CD4 cells and a statistically significant reduction in viral load in their peripheral blood (P<0.001) compared to mice given control cells...

Frost & Sullivan Recognizes ESBATech's Innovation in Developing Antibody Fragments for Biologic Therapeutics

... antibody fragment's unique capacity to topically and locally deliver high drug concentrations to targeted sites, coupled with strikingly low systemic load and the resulting lowered risk of drug interactions, puts it at the forefront of innovation ushering in a new era in medicine." In recognition of...

Researchers: Molecular forklifts overcome obstacle to 'smart dust'

...appens with traditional assays. But then, activated by a flash of light, molecular shuttles start pushing the forklifts into a second zone, where they load aboard fluorescent particles, or tags. They move their cargo to the third zone, at the edge of the circle. There, over several hours, they crowd again...

GridGain 2.1 - Open Cloud Platform Enables Development of Native Cloud Applications

... Cloud-aware class loading Virtualized cloud support with cross-cloud deployment Advance MapReduce implementation Comprehensive early and late load balancing capabilities Automatic and dynamic data partitioning and processing co-location Advanced scheduling management Revamped deployment i...

Human Genome Sciences Announces Albuferon(R) Meets Primary Endpoint in Phase 3 Trial in Chronic Hepatitis C

...nd the primary efficacy endpoint was non-inferiority to peginterferon alfa-2a, based on a comparison of the rate of SVR, defined as undetectable viral load (HCV RNA < 10 IU/mL) at Week 48 (24 weeks following completion of treatment). "We are encouraged that albinterferon alfa-2b met the prim...

Dr. Gail Naughton Speaks on Histogen's Business Plan and the Rise of Bioaesthetic Medicine during Commercial Translation of Regenerative Medicine

... in the field of oncology." Dr. Naughton presented data for the first time supporting the ability of ExCeltrix to diminish or eliminate tumor load in preclinical trials. Studies were performed with three rapidly growing human tumor cell lines: melanoma, adenocarcinoma, and glioma. Cancer cells we...

Bio-Tec Environmental Introduces Their New Plastic Additive Showing 45% Biodegradation of Plastics in Just 14 Days

...ecessor in economy and performance. Their new formulation biodegrades materials up to five times faster than Bio-Batch. It can be used at 0.7% by load weight to render most plastic materials 100% biodegradable in time. As validated by the ASTM method of anaerobic biodegradation, the accelerated rate ...

TIBCO Speeds Drug Discovery for Chemists

...ture-searching capabilities -- Share analysis, workflow, and decision points with key collaborators in a common analysis environment. -- load chemical data from chemical cartridges and SD files About TIBCO TIBCO Software Inc. (Nasdaq: TIBX ) is a leading provider of enterprise analytics ...

TorreyPines Therapeutics Sells Alzheimer's Disease Genetics Program to Eisai

...r's disease, the other being a gamma secretase modulator (GSM) program. Recently, a lead compound from the GSM program has been shown to reduce plaque load and Abeta peptide levels in the brains of Tg2576 Alzheimer's disease model mice after seven months of oral dosing. TorreyPines is currently seeking a ...

The Elmasonic S Ultrasonic Cleaner: Designed for the Scientific Laboratory

...in Degas mode for 10 minutes. The Elmasonic S Ultrasonic cleaner assures reproducible sample preparation with its microprocessor, which senses the load and modulates the generator to deliver the same mixing for every run. The Autostart feature begins sonication only after the set temperature is reach...

Idenix Pharmaceuticals Reports Third Quarter and Nine Month Financial Results

...treatment in each of the 800 mg, 400 mg, 200 mg and 100 mg dosing cohorts (n=8 per treatment group). Patients receiving placebo (n=8) had a mean viral load increase of 0.10 log10 over the same treatment period. The safety profile of IDX899 observed during this study was comparable to placebo, with no seri...

Anadys Pharmaceuticals Commences Dosing ANA773 in Hepatitis C Patients

...subsequent cohorts will be selected based on viral load and tolerability data from the 800 mg cohort. "T... complementary HCV programs advancing toward viral load data, we look forward to demonstrating the breadth...subsequent cohorts will be selected based on viral load and tolerability data from the 800 mg cohort. Anad...

Sangamo BioSciences Presents Data at ICAAC Demonstrating 'In Vivo' Protection Against HIV Infection by CCR5-ZFN Therapeutic

...TM)) resulting in an increase in CD4 T-cell counts and a reduction in viral load in an animal model of HIV infection. The presentation, entitled, "Establish... of CD4 cells and a statistically significant seven-fold reduction in viral load in their peripheral blood (P<0.001) compared to mice given control cells. A...

Abbott's XIENCE V(TM) Drug Eluting Stent Wins Prestigious Chicago Innovation Award

... Abbott has received in six years. Most recently, the company's m2000(TM) molecular diagnostic instrument in combination with the RealTime HIV-1 viral load test received the honor in 2007. In 2005, the company's PathVysion(TM) breast cancer test received the honor, and in 2003, HUMIRA(TM), the first human...

Anadys Pharmaceuticals Reports Third Quarter 2008 Financial Results and Highlights

...period of three days. Anadys expects to have viral load data from this study in the first quarter of 2009....subsequent cohorts will be selected based on viral load and tolerability data from the 800 mg cohort. --...re clinical trials, the timing for obtaining viral load data and expectations regarding such data, as well...