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cycle in Biological Technology

Paper in Cell Cycle Reports Alfacell's ONCONASE(R) Targets siRNA

SOMERSET, N.J., Oct. 9 /PRNewswire-FirstCall/ -- Alfacell Corporation (Nasdaq: ACEL ) today announced that a paper published in Cell Cycle (2008; Vol. 7, Issue 20) reports that ONCONASE (ranpirnase) targets small interfering RNA (siRNA), likely within the RNA-induced silencing complex (RISC) ...

ValGenesis, Inc. Announces Worldwide Release of Validation Life Cycle Management System - ValGenesis 2.0

FREMONT, Calif., June 26 /PRNewswire/ -- ValGenesis, Inc., a leading provider of Enterprise Validation Management software solutions, announced the worldwide availability of ValGenesis 2.0, the latest version of its breakthrough Web-based, multi-site, scalable validation life cycle management ...

HealthEast Care System Selects Concuity's ClearContracts to Increase Contract Analysis and Negotiation Capabilities and Improve Revenue Cycle Management

VERNON HILLS, Ill. and DUBLIN, Ireland, April 21 /PRNewswire-FirstCall/ -- Concuity, a healthcare division of Trintech (Nasdaq: TTPA ) and a leading provider of contract management and revenue recovery technology ("Peer Reviewed by HFMA") and services, today announced that HealthEast Care Sys...

Canadian Centre for DNA Barcoding to Participate in Microchip Biotechnologies Early Access Program for Microchip-Based DNA Sample Preparation and Cycle Sequencing

DUBLIN, Calif., April 8, 2008 /PRNewswire/ -- Microchip Biotechnologies, Inc. (MBI) is pleased to announce that the Canadian Centre for DNA Barcoding (CCDB), at the Biodiversity Institute of Ontario, University of Guelph, will be the first participant to join MBI's early access program for the...

FluForecast(R) Replikin Count(TM) Predicts That the H5N1 Cycle Which Began in 1996 Is Now Over

BOSTON, Feb. 11 /PRNewswire/ -- Replikins Ltd. announced that the quantitative analysis of Replikin Count(TM) in the virus gene structure predicts that the current H5N1 cycle is over. Sporadic outbreaks may continue, but the rapid epidemic spread and high mortality characteristics are expected...

IMPAC Medical Systems to Offer Revenue Cycle Inc.'s Array of Oncology Products and Services to Customers

LOS ANGELES, Oct. 28 /PRNewswire/ -- IMPAC Medical Systems, Inc., an Elekta company, and global leader in oncology information technology solutions, and Revenue Cycle Inc., a comprehensive business-side evaluation, analysis and solutions provider for the oncology market, today announced an agr...

Pacific Cycle rides full speed into RFID

Pacific Cycle built a significant presence in the bicycle industry by buying some of the most traditional, old-line brands on the market. But the Madison, Wis.-based company has jumped full speed into the future with the integration of radio frequency identification (RFID) technology into its sys...

Quantitative Analysis of the Cell Cycle in Imaging Applications

Introduction Quantitative analysis of stages in the cell cycle is commonly used in cell biology since many pharmacological interventions aim to modulate the cell cycle in some way. We present here an application that can be used in adherent cells and optionally mul...

siRNA screening of the cell cycle with two dynamic GFP sensors (from Discovery Matters Issue 1, July 2005)

M. Kenrick, S. Hancock, S. Stubbs, and N. Thomas GE Healthcare, The Maynard Centre, Cardiff, UK Recent advances in siRNA methodologies and the development of high-throughput image analysis platforms such as the IN Cell Analyzer have revolutio...

Automated Fluorescent-Tag Cycle Sequencing

Application of the RoboCycler Gradient 96 temperature cycler Douglas Drake Stratagene Cloning Systems, Inc. Stratagenes RoboCycler Gradient 96 temperature cycler *,# with Hot Top Assembly can be used to perform fluorescent-tag cycle sequencing using the ABI PRISM dye te...

Biotech industry reaches midpoint in 50-year maturation cycle

If we assume that the biotech industry started in the late 1970s with the first IPOs taking place in 1980 (Amgen and Cetus), then biotech is already an industry more than 25 years old. An interesting article in Genetic Engineering News ( GEN ) on March 1 states unequivocally that most indust...

Is venture capital dead? No, but its beginning a new cycle

Howard Anderson, who teaches courses on early-stage companies at the Massachusetts Institute of Technology, founded or co-founded three venture capital funds. He was a self-described financial samurai. Now, hes hanging up his sword, declining to raise new money for his funds. Theres too much ven...

Synthetech Reports First Quarter Fiscal 2010 Results

...hipments arising from these projects. Synthetech operates in a challenging business environment, characterized by the unpredictable dynamics and life cycle of pharmaceutical projects, which can lead to rapid fluctuations in the mix of projects and revenues. As the uncertainties inherent in drug developme...

Cardinal Health Completes Biotech Acquisition

...ity, and deliver better care to patients. With a focus on making supply chains more efficient, reducing hospital-acquired infections and breaking the cycle of harmful medication errors, Cardinal Health develops market-leading technologies, including Alaris(r) IV pumps, Pyxis(r) automated dispensing and pa...

Cornerstone Therapeutics Announces Closing of Chiesi Transaction

...re rights to underpromoted, patent-protected, branded respiratory or related pharmaceutical products, or late-stage product candidates; implement life cycle management strategies to maximize the potential value and competitive position of the Company's currently marketed products, newly acquired products a...

Kendle Realigns C-Suite Leadership to Drive Increased Innovation, Productivity and Organizational Efficiency

...nge of early- to late-stage clinical development services for the world's biopharmaceutical industry. Our focus is on innovative solutions that reduce cycle times for our customers and accelerate the delivery of life-enhancing drugs to market for the benefit of patients worldwide. As one of the world's lar...

Kendle Appoints Stephen Cutler, PhD Senior Vice President and Chief Operating Officer

...nge of early- to late-stage clinical development services for the world's biopharmaceutical industry. Our focus is on innovative solutions that reduce cycle times for our customers and accelerate the delivery of life-enhancing drugs to market for the benefit of patients worldwide. As one of the world's lar...

WuXi PharmaTech Schedules Second-Quarter 2009 Earnings Release

...services throughout the drug and medical device R&D process. WuXi PharmaTech's services are designed to help its global partners in shortening the cycle and lowering the cost of drug and medical device R&D. The operating subsidiaries of WuXi PharmaTech are known as WuXi AppTec. For more information...

UCSF researchers help crack parasite genome, identify drug leads

...as senior author on the PLoS paper on the compound discovery work. The current drug also is not ideal as it mainly targets the adult stage in the life cycle of the parasite, enabling immature parasites to escape and re-establish the infection. "Together, these two projects offer powerful tools to combat...

University of Florida Shands Cancer Center Selects OnCore(r) to Support its Collaborative Research Goals

...s. OnCore-CRM offers a comprehensive set of modules for managing all aspects of clinical research:   Protocol & Subject Life cycle Management Subject Safety Management Protocol & Subject Calendar Management Study Financials Management Electronic Data Capture and Da...

Significant Milestone Marks the Beginning of FDA-Authorized Breast Cancer Trial

...er patients who have failed conventional therapy. According to Mr. Chuck Broes, CEO of QI, "This achievement marks a significant milestone in the life cycle of our company, and we look forward with great hope and commitment as we aspire to a successful trial outcome." The clinical trials involve t...

Cornerstone Therapeutics Inc. Announces Record Date and Meeting Date for Special Meeting of Stockholders for Vote with Respect to Charter Amendments

...d pharmaceutical products, or late-stage product candidates; implement life cycle management strategies to maximize the potential value and competitive posit...ed pharmaceutical products or late-stage product candidates; implement life cycle management strategies to maximize the potential value and competitive posit...

Schering-Plough Announces Phase II and III Data for Corifollitropin Alfa

... mean (SD) number of oocytes retrieved per started cycle in the corifollitropin alfa group was 13.3 (+/-7.3... injections of 0.1 mg of GnRH agonist (starting on cycle day 21). Ovarian stimulation was started with a si... mean (SD) number of oocytes retrieved per started cycle was 15.4 (+/-6.7) in the 100 mcg dose group and 17...

Vega Picks Tennessee Firm to Assist with Construction of Biomass Plant in Georgia

...bi-products. For example, manure, garden waste and crop residues are all sources of biomass. It is a renewable energy source based on the carbon cycle , unlike other natural resources such as petroleum , coal , and nuclear fuels. The use of biomass fuels can therefore contribute to wa...

Hospira Announces New Contract With MedAssets for Intravenous Solutions, Renewal of Infusion Devices Agreement

... MedAssets (Nasdaq: MDAS ) partners with healthcare providers to improve their financial strength by implementing spend management and revenue cycle solutions that help control cost, improve margins and cash flow, increase regulatory compliance, and optimize operational efficiency. MedAssets serves...

Kendle Names Jarrod Pontius Chief Legal Officer

...nge of early- to late-stage clinical development services for the world's biopharmaceutical industry. Our focus is on innovative solutions that reduce cycle times for our customers and accelerate the delivery of life-enhancing drugs to market for the benefit of patients worldwide. As one of the fastest-gro...

Natural Fuels Industries Eyes 'Biomass Rich' Georgia for Production Facility

...by-products. For example, manure, garden waste and crop residues are all sources of biomass. It is a renewable energy source based on the carbon cycle , unlike other natural resources such as petroleum , coal , and nuclear fuels. The use of biomass fuels can therefore contribute to wa...

Helix BioPharma to Present L-DOS47 Analytical Method Development Findings at 2009 AAPS National Biotechnology Conference

...alled the urea cycle, to produce an anti-cancer effect. It is based upon a naturally occurring enzyme called urease that essentially reverses the urea cycle by breaking down urea into metabolites that include ammonia and hydroxyl ions. By doing so at the site of cancerous tissues in the body, L-DOS47 is be...

WuXi PharmaTech to Present at Third Annual Jefferies Healthcare Conference

...rvices throughout the drug and medical device R&D process. WuXi PharmaTech's services are designed to assist its global partners in shortening the cycle and lowering the cost of drug and medical device R&D. WuXi PharmaTech's operating subsidiaries are known as WuXi AppTec. For more information, ple...

NeurogesX Provides U.S. Regulatory Update for Qutenza(TM)

...y complete enrollment, analyze the data, and submit an NDA amendment prior to the assigned PDUFA date. Submission of this amendment during the review cycle may result in an extension of the PDUFA date. Anthony DiTonno, CEO of NeurogesX, commented, "With the FDA's approval of our protocol, we believe...

Proteolix Presents Clinical Data from Two Clinical Studies of Carfilzomib in Multiple Myeloma at the 14th Congress of the European Hematology Association

...-one percent of the 18 patients evaluable for efficacy achieved very good partial, partial or minor responses. Responses occurred in the first 28-day cycle of treatment at doses well below the maximum-tolerated dose for either lenalidomide or carfilzomib alone. Initial responses improved with continued t...

Kendle Expands Asia/Pacific Operations with Opening of Offices in Kuala Lumpur, Bangkok and Manila

...nge of early- to late-stage clinical development services for the world's biopharmaceutical industry. Our focus is on innovative solutions that reduce cycle times for our customers and accelerate the delivery of life-enhancing drugs to market for the benefit of patients worldwide. As one of the fastest-gro...

Cimzia(R) (certolizumab pegol) Provides Long-Term Remission and Response Rates in Infliximab-Refractory Crohn's Patients

...y and hospitalization. Crohn's disease has been estimated to affect as many as half a million Americans. People with Crohn's can experience an ongoing cycle of flare-up and remission throughout their lives. Together with ulcerative colitis, Crohn's disease is an inflammatory bowel disease (IBD). Abo...

Ascenta Therapeutics Announces Presentation of Promising Results From Clinical Trials of AT-101 in Prostate, Brain, and Lung Cancers at 2009 ASCO Annual Meeting

...cent of those with measurable disease achieved partial responses per RECIST. A reduction in circulating tumor cells was also reported after the first cycle of treatment and tended to be predictive of RECIST response. AT-101 was well tolerated in this combination as the majority of adverse events were Gra...

OncoGenex Pharmaceuticals Announces OGX-011 Treatment Provides Survival Benefit in Randomized Phase 2 Trial in Advanced Metastatic Prostate Cancer

...fect in the OGX-011 plus docetaxel arm was observed with statistically significant declines in serum clusterin levels within the first cycle of trial treatment when compared to levels in the docetaxel arm. OGX-011 has been shown to primarily target tissue clusterin levels wi...

OncoGenex Pharmaceuticals Announces OGX-427 Treatment Demonstrates Safety, Evidence of Declines in Circulating Tumor Cells and Reductions in Tumor Markers in a Phase 1 Cancer Trial

...rogression or toxicity. In those groups receiving OGX-427 in combination with docetaxel, 75mg/M(2) docetaxel was administered on Day 1 of every 3-week cycle starting after completion of the OGX-427 loading doses. Safety Results Patients enrolled had a diagnosis of breast, ovarian, prostate or non...

MIT, BU engineer cellular circuits that count events

...r, ending its own transcription and setting up the gene for the second invertase to be transcribed next. When the second stimulus is received, the cycle repeats: The second invertase is produced, then flips the DNA, setting up the third invertase gene for transcription. The output of the system can be ...

DuPont Innovation Addressing Major Global Market Trends

...," Kullman said at the Sanford Bernstein Strategic Decisions Conference. "That simple statement describes us whether we're at the peak of an economic cycle or experiencing a global recession -- innovation is a critical lever at all times for DuPont. Our innovation objectives are focused on key global mar...

Gene Network Sciences Announces Broad Cancer Collaboration With UCSF and Initial Results

...NS. Financial terms of the agreement were not disclosed. GNS and UCSF have utilized REFS(TM) to discover and validate novel mediators of the cell cycle transition, which is a critical determinant of the rate of cancer cell proliferation and tumor growth. These results were presented by UCSF researcher...

Amgen Exercises Option for Exclusive License to Cytokinetics' Cardiac Contractility Program That Includes CK-1827452

...myosin activators accelerate the rate-limiting step of the myosin enzymatic cycle and shift the enzymatic cycle in favor of the force-producing state. This inotropic mechanism results no...
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