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Vector in Biological Technology
Lentigen Licenses Fundamental Lentiviral Vector Technology Patent From the University of Cambridge
BALTIMORE, April 3, 2008 /PRNewswire/ -- Lentigen Corporation today announced an exclusive licensing agreement with Cambridge Enterprise, the organization responsible for licensing technologies from the University of Cambridge (U.K.), for a fundamental patent in the area of lentiviral vector t...OriGene Announces 37,000 ORF cDNA Clones in a GFP Vector
ROCKVILLE, Md., Oct. 31 /PRNewswire/ -- OriGene Technologies, Inc. announces its flagship products, TrueORF cDNA clones, are available now in a GFP (green fluorescence protein) vector, enabling easy transfection monitoring and protein expression. With this launch, over 25,000 human ORF (open re...Key words: adenoviral vector ● viral transduction ● NTR ● IN Cell Analyzer ● gene delivery Biological assays developed in cultured and primary cells can greatly aid secondary screening as well as lead and target validation, but ...
Performance of Ad-A-Gene EGFP-MAPKAP-k2: an adenoviral vector gene delivery system
Key words: adenoviral vector • viral transduction • EGFP • IN Cell Analyzer • gene delivery Biological assays developed in cultured and primary cells can greatly aid secondary screening as well as lead and target validation, but the...Key words: adenoviral vector • viral transduction • EGFP • IN Cell Analyzer • gene delivery There is a requirement in the drug discovery process to investigate lead candidate drugs arising from primary screens and to validate those ...
Iezzi M, Kouri G, Fukuda M, Wollheim CB (2004) Synaptotagmin V and IX isoforms control Ca 2+ -dependent insulin exocytosis. J Cell Sci 117:3119-3127. In a recently published paper in the ...
Mammalian Expression Vector for Efficient Cloning of PCR Fragments
Fast and efficient PCR cloning with pcmv-script PCR cloning kit Tanya Hosfield Kerstien Padgett Tim Sanchez Quinn Lu Stratagene Cloning Systems, Inc. Stratagene has expanded the applications of the PCR-Script cloning strategy by introducing a new vector for high-ef...A New Lambda Vector for Mammalian Expression
The Lambda ZAP -CMV vector for efficient library construction and mammalian expression Quinn Lu Tanya Hosfield Cherie Dewar Tim Sanchez Mike Kobrin Stratagene Stratagenes new lambda cloning vector, the Lambda ZAP -CMV vector,* contains the left...An Epitope Tagging Vector for Gene Expression in Mammalian Cells
An Epitope Tagging Vector for Gene Expression in Mammalian Cells Use tag-specific antibodies to study expressed genes Tanya Hosfield Quinn Lu Stratagene The pCMV-Tag1 vector is an epitope tagging vector designed for gene expression in mammalian cells. A target gene insert...Efficient gene transfer and high-level protein expression within a variety of cells Tanya Hosfield Lisa Eldridge Stratagene Recombinant adenoviruses provide a versatile means of gene delivery and expression. We describe the AdEasy adenoviral vector system, ###,W ...
A New C-Terminal GST Vector for Protein Production in S. pombe
Versatile eukaryotic expression and protein purification vector Quinn Lu Tanya Hosfield Stratagene Stratagene has constructed and tested the new pESP-3 vector, which can be used for C-terminal fusion with glutathione-S-transferase (GST) and for protein production i...Mammalian and Bacterial Expression in One Vector
Novel pdual expression vector for high-level expression in both mammalian and bacterial cells Kerstien A. Padgett Joseph A. Sorge Stratagene Stratagene has developed the pdual expression vector,* which permits high-level expression of heterologous genes in both eukaryotic ......inson's Disease CERE-120 is composed of an adeno-associated virus (AAV) vector carrying the gene for neurturin, a naturally occurring protein known to rep...ene delivery. Ceregene's clinical programs include CERE-110, an AAV2 based vector expressing nerve growth factor that is currently in a multi-center, control...
...gene delivery that allows for localized control of gene uptake. The Gene Activated Matrix comprises any biocompatible matrix containing a gene or DNA vector encoding for a growth factor or any therapeutic protein. The Gene Activated Matrix technology allows for a broad spectrum of formulations and the use...
...issued by Clavis Pharma. About Clavis Pharma Clavis Pharma ASA is an oncology focused pharmaceutical company using its proprietary Lipid vector Technology (LVT) platform to create New Chemical Entities (NCEs), by significantly improving already established drugs. The improvements are achieved ...
...y over the coming years. About Clavis Pharma Clavis Pharma ASA is an oncology focused pharmaceutical company using its proprietary Lipid vector Technology (LVT) platform to create New Chemical Entities (NCEs), by significantly improving already established drugs. The improvements are achieved ...
Cynvec to Present at The 2009 New York Venture Summit
... CYN 101 is a replication defective, apoptotic RNA vector that has shown tumor eradication and highly signif...motherapies. Cynvec is also developing a companion vector that will provide an in vivo, quantitative, real t... CYN 101 in the third quarter of 2009. The sindbis vector has demonstrated in vivo efficacy delivering a var......ation titled "Cynvec: Breakthrough Oncolytic Viral vector Therapy with Sindbis" at the 11th Annual Shanghai ... CYN 101 is a replication defective, apoptotic RNA vector that has shown tumor eradication and highly signif...motherapies. Cynvec is also developing a companion vector that will provide an in vivo, quantitative, real t...
...e final data set is (p=0.006). There were no major clinically meaningful imbalances in baseline characteristics in the PROSTVAC(TM) and control vector treated arms. PROSTVAC(TM) immunotherapy was well tolerated, with some patients having injection site reactions (40-60%), and systemic symptoms...
Vaxart Begins Animal Testing of H1N1 Flu Vaccine Candidate
...matching the pandemic strain into Vaxart's pre-constructed vector. Vaxart's vector grows quickly and reproducibly in cell culture using a standard process. ...s under development. Vaxart has shown that prior exposure to their platform vector does not impact the performance of later vaccinations. The company has prev...ImmunoVaccine Technologies Partners with FIT Biotech to advance a therapeutic HIV vaccine
...iotech's GTU(R) MultiHIV DNA plasmid with IVT's DepoVax(TM) vaccine delivery system to advance a therapeutic HIV vaccine. "DepoVax(TM) will act as a vector to deliver FIT Biotech's GTU(R) MultiHIV DNA vaccine and our goal is to develop a more sophisticated and efficient HIV vaccine candidate," commented D......nuated strain of the company's core technology, MVA-BN(R), which is the basis for its smallpox vaccine, IMVAMUNE(R). MVA-BN(R) also holds promise as a vector for delivering recombinant vaccines. Bavarian Nordic has asserted four US patents as a basis for its infringement action. The claim in this case is th...
Cynvec to Present at New York Biotechnology Association 18th Annual Meeting
... CYN 101 is a replication defective, apoptotic RNA vector that has shown tumor eradication and highly signif...motherapies. Cynvec is also developing a companion vector that will provide an in vivo, quantitative, real t...n cancer in the third quarter of 2009. The sindbis vector has also demonstrated in vivo efficacy delivering ......tients) and left ventricular function/remodeling (5 patients). Of the nine patients treated, two with low levels of pre-existing antibodies to the AAV vector did not show improvement in these parameters. "This peer reviewed publication of our results further validates our target and approach and we are...
Atritech Completes $30 Million Financing
... Partners and insider investments from Prism Ventures, Tullis-Dickerson and vector Group. Over the past 3 years, the Company has raised approximately $75 mil... Venture Partners, Thomas McNerney Partners, Tullis-Dickerson Partners, The vector Group, Thoma Cressey Funds, SightLine Funds and Affinity Capital. For more ...Cynvec to Present at the BIO National Venture Conference
... CYN 101 is a replication defective, apoptotic RNA vector that has shown tumor eradication and highly signif...motherapies. Cynvec is also developing a companion vector that will provide an in vivo, quantitative, real t...n cancer in the third quarter of 2009. The sindbis vector has also demonstrated in vivo efficacy delivering ...Energy Leaders Gather in Houston; Call for Balanced, Careful Approach to Energy Policy
...earch, American Biofuels Council; Steve Winn, CEO, Nuclear Innovation North America LLC; Kevin Howell, President, NRG Texas; Brett Perlman, President, vector Associates; and Mark Kapner, Senior Strategy Planner, Austin Energy. Video of the event will soon be made available on www.houston.org and at w...DNA2.0 Introduces Freedom of Expression With a New Family of Bacterial Expression Vect:ors
...provider of synthetic genes. DNA2.0 will continue to develop new vectors with additional features in order to provide customers with the most advanced vector technology available. "DNA2.0's pJexpress vectors routinely express protein more efficiently than traditional pET vectors and without IP cons...GeoVax Labs, Inc. Reports Fourth Quarter and Year-End 2008 Financial Results
...the developer of the vaccine and GeoVax's Vice President of Research and Development, also presented these same results at the Viral vector Vaccines 2008 meeting, at the Wellcome Trust Conference Center near Cambridge, U.K., on September 28, 2008. * Phase 2a Preventive Hum...Cynvec LLC(SM) to Present at the Cowen and Company 29th Annual Health Care Conference
...nation with licensed chemotherapies. Cynvec is also developing a companion vector that will provide an in vivo, quantitative, real time cancer diagnostic. Cy...ials of CYN 101 in ovarian cancer in the third quarter of 2009. The sindbis vector has also demonstrated in vivo efficacy delivering a variety of cytokines di...GeneCopoeia Introduces Genome-Wide MicroRNA (miRNA) Functional Analysis Tools
... reagents and tools. They include 1) miExpress(TM) vector based precursor miRNA expression clones; 2) miTarg...A RT-qPCR system. Constructed in a lentiviral vector system, miExpress(TM) precursor miRNA expression ...750), mouse (450), and rat (270). These lentiviral vector based expression constructs allow efficient transd...Genetic information personalizes warfarin prescribing
...san older technique called linear regression and a newer one called support vector regressionwere equally successful when a combination of clinical informatio...ence for it because it's much easier to understand and use than the support vector regression model," says Page, noting that the program is easily accessed in...Lentigen and Expression Therapeutics Sign Hemophilia Co-Development Agreement
...ic need." About Lentigen Corporation Lentigen Corporation is a privately owned biotechnology company focused on the development of lentiviral vector technology for a wide range of therapeutic, vaccine, and research applications in biotechnology and medicine. Lentiviral vectors are the most efficien...Bavarian Nordic's Case Against Oxford BioMedica
...nuated strain of the company's core technology, MVA-BN(R), which is the basis for its smallpox vaccine, IMVAMUNE(R). MVA-BN(R) also holds promise as a vector for delivering recombinant vaccines. Bavarian Nordic has asserted three US patents as a basis for its infringement action. The claim in this case is t...Imugene and Merial Establish Strategic Alliance
... and drugs. Imugene owns the worldwide rights to the Fowl Adenoviral vector Delivery System for poultry and the Porcine Adenoviral vector Delivery System for pigs. For more information please visit the Imug......o elevate drooping cheeks, chin, or eye brows. The difference of the Frame Thread Lift procedure as opposed the Contour Lift is that Dr. Woo Jung Ho's vector technique creates a "frame" on the face. The frame effect supports the structure and tissues--from low to high. There have been more than a ...
Virginia Tech researchers discover how mosquitoes avoid succumbing to viruses they transmit
...erived small RNAs modulate pathogenesis in disease vector mosquitoes," by Myles; Michael R. Wiley of Ambler,...cted a mosquito called Aedes aegypti, an important vector of yellow fever and dengue. In response, the mosqu...virus a virus that is transmitted by an arthropod vector , said Myles. The researchers used an Illumina mac...Ceregene Announces Clinical Data From Phase 2 Clinical Trial of CERE-120 for Parkinson's Disease
...ut CERE-120 CERE-120 is composed of an adeno-associated virus (AAV) vector carrying the gene for neurturin (NTN), a naturally occurring protein known ...ene delivery. Ceregene's clinical programs include CERE-110, an AAV2 based vector expressing nerve growth factor that is about to enter a Phase 2 study for t...TRIDELITY Display Solutions Partners With Two Of The World's Leading Imaging Software Companies
...nterfaces and powerful tools to satisfy the most demanding needs in image data analysis, optical or electron microscopy imaging, molecular simulation, vector and flow visualization, and finite element modeling. "For a long time we were in doubt whether autosterescopic 3D display technology can me......tors as standalone oncolytic therapeutics, delivery systems for monoclonal antibodies and cytokines as well as cancer diagnostic products. The Sindbis vector system, originally developed at NYU School of Medicine, represents a unique, patented platform technology for numerous commercial applications. The co...
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