Sequence in Biological Technology

First Catalog Cancer Biochip for Sequence Capture Now Available from febit

LEXINGTON, Mass. and HEIDELBERG, Germany, July 13 /PRNewswire/ -- febit holding gmbh announced today the launch of the first human cancer biochip for HybSelect, febit's highly automated technology for sequence capture, enabling targeted Next-Generation Sequencing (NGS). The new catal...

It's Not Just the Sun: deCODE Discovers Sequence Variants Affecting Susceptibility to Skin Cancer

REYKJAVIK, Iceland, July 6 /PRNewswire-FirstCall/ -- Scientists at deCODE genetics (Nasdaq: DCGN ) and academic colleagues from Europe and the United States today present in the journal Nature Genetics the discovery of common genetic risk factors for basal cell carcinoma (BCC) that affect peop...

GenomeQuest, Inc. Announces Digital Gene Expression Solution Within Its Sequence Data Management Platform

DigEx Solution offers completely interactive gene-level database to explore, understand, manage, and share next-generation sequencing DigEx runs. WESTBOROUGH, Mass., May 5 /PRNewswire/ -- GenomeQuest, Inc., the leader in sequence data management, today announced that it has released a Digital...

New cow genome sequence released

Scientists from the University of Maryland have published their assembly of the domestic cow ( Bos taurus ), an important new resource for the genetics community. The new version of the cow genome improves considerably on other assemblies, in terms of both completeness and accuracy. The article de...

Automated Sequence Capture for Next-Generation Sequencing Paves the Way for Personalized Medicine

HybSelect(TM) first to provide high coverage and megabase capacity for the next generation sequencing community LEXINGTON, Mass. and HEIDELBERG, Germany, March 16 /PRNewswire/ -- febit today announced the official launch of its new sequence capture technology HybSelect. In several biomedica...

Transgenomic Awarded SBIR Grant to Support Development of SURVEYOR(R) Endonuclease Adaptor-ligated Libraries (SEAL) for Determining Whole Genome Sequence Variation

OMAHA, Neb., Nov. 20 /PRNewswire-FirstCall/ -- Transgenomic (OTC Bulletin Board: TBIO) today announced that it has been awarded a Phase I Small Business Innovation Research (SBIR) award by the National Science Foundation (NSF) to support the development of its proposed SURVEYOR Endonuclease Adapto...

RainDance Technologies Delivers RDT 1000, Sequence Enrichment Solution to The Genome Center at Washington University School of Medicine in St. Louis

LEXINGTON, Mass., Nov. 5 /PRNewswire/ -- RainDance Technologies, Inc., a provider of innovative microdroplet-based solutions for human health and disease research, today announced that it has shipped its new RDT 1000 instrument and Sequence Enrichment application to The Genome Center (GC) at t...

RainDance Technologies to Present Workshop on Sequence Enrichment Using Innovative Microdroplet-Based Solutions at ASHG 2008

LEXINGTON, Mass., Nov. 3 /PRNewswire/ -- RainDance Technologies will present a workshop on sequence enrichment using innovative microdroplet-based solutions at the American Society of Human Genetics (ASHG) 58th Annual Meeting in Philadelphia on Thursday, November 13th. Recent advances in DNA...

RainDance Technologies Delivers RDT 1000, Sequence Enrichment Solution to JCVI

LEXINGTON, Mass., Oct. 30 /PRNewswire/ -- RainDance Technologies, Inc., a provider of innovative droplet-based microfluidic solutions for human health and disease research, today announced that the J. Craig Venter Institute (JCVI), a not for profit genomic research organization located in Rock...

New Online Tutorials for Sequence Similarity Search Tools BLAST and FASTA

Comprehensive tutorials on sequence similarity search tools BLAST and FASTA enable researchers to quickly and effectively use these invaluable resources. Seattle (PRWEB) July 17, 2008 -- OpenHelix today announced the availability of new tutorial suites on two highly u...

Transgenomic Introduces SURVEYOR(R) Endonuclease Adaptor-Ligated Libraries (SEAL) for Determining Whole Genome Sequence Variation

High Throughput Technology Identifies DNA Variations Between a Reference Genome and Test Genome OMAHA, Neb., June 17 /PRNewswire-FirstCall/ -- Transgenomic (OTC Bulletin Board: TBIO) today announced that it is developing SURVEYOR Endonuclease Adaptor-ligated Libraries (...

A Smoking Gene: deCODE Shows How a Single Variant in the Sequence of the Genome Confers Nicotine Dependence and Risk of Lung Cancer and Other Disease

Findings will be applied to diagnostic efforts and will be integrated into the deCODEme(TM) service REYKJAVIK, Iceland, April 2, 2008 /PRNewswire-FirstCall/ -- Cigarette smoking is a major public health problem that contributes to millions of deaths around the world each ...

Gene Codes Corporation Announces Version 4.8 of Sequencher Software for DNA Sequence Assembly & Analysis

ANN ARBOR, Mich., Oct. 24 /PRNewswire/ -- Gene Codes Corporation, a leading bioinformatics software developer, announced the immediate availability of the next version of Sequencher, its award-winning Deoxyribonucleic acid (DNA) sequence assembly and analysis program. Researchers in academic ...

International science consortium publishes analysis of domestic cattle genome sequence

The U.S. Department of Agriculture and the National Institutes of Health announced today that an international consortium of researchers has published the genome of domestic cattle, the first livestock mammal to have its genetic blueprint sequenced and analyzed. The landmark research will bolster ...

Intradigm Receives Notice of Allowance for Key RNA Interference (RNAi) Patent Covering Potent siRNA Sequence

Issuance Will Give Company Patents in Each of the Three Critical Areas of RNAi Therapeutic Development PALO ALTO, Calif., March 17 /PRNewswire/ -- Intradigm Corporation, a leading developer of targeted, systemic RNA interference (RNAi) therapeutics, today announced that the United States Pate...

A simple method to sequence from bacterial colonies using [a-33P] radiolabeled ddNTPs and Thermo Sequenase

Introduction In traditional DNA sequencing systems, sequencing products are radioactively labeled using either endlabeled primers or by the incorporation of radiolabeled dNTPs during primer extension. Successful sequencing results produced by these two labeling methods are hi...

Monitoring Bacterial Genetic Diversity in a Freshwater Lake Using TTGE and DNA Sequence Analysis

Richard Hastings, Jon Saunders and Alan McCarthy School of Biological Sciences, University of Liverpool, Liverpool, UK Introduction Microbial ecology is now firmly focused on the genotypic analysis of naturally-occurring assemblages...

Using the DCode System to Identify DNA Sequence Variation for Studies of Population Structure in Marine Organisms

Patrick M. Gaffney, Elizabeth A. Orbacz, and Ziniu Yu, College of Marine Studies, University of Delaware, Lewes, Delaware. Introduction DNA polymorphisms are useful tools for ecological and evolutionary studies ...

CastAway Precast Gels for Rapid Automated DNA Sequence Analysis

The first precast gels for automated sequencing and genetic analysis Stephen Roemer Mary Jensen Harry Osterman Mark Vanek LI-COR Biotechnology Division LI-COR and Stratagene release the first commercially available precast gels for automated DNA sequencing and g...

Detect Single Nucleotide Sequence Changes with Mx4000 Molecular Beacon Allelic Discrimination Kits

Allelic discrimination kits with excellent specificity, sensitivity, and assay throughput Xiuyuan Hu Lingyu Chen Stratagene Because of their unique hairpin conformation, molecular beacon probes can recognize single base differences, making them ideal fo...

Expression and Purification of Recombinant Proteins That Have Native Amino Acid Sequence

One column purification of protein with native amino acid sequence Denise L. Wyborski * John C. Bauer * Barbara McGowan * Joseph A. Sorge * Peter Vaillancourt Stratagene Cloning Systems, Inc. Stratagene has improved the Affinity protein expression and purification system by t...

Novavax Reports Second Quarter 2009 Financial Results

...uenza program by manufacturing a cGMP-quality batch of the company's VLP vaccine candidate against this virus within 11 weeks of receiving the genetic sequence of the pandemic virus strain from the Centers of Disease Control. "Our progress since the first quarter has been transformational," said...

SmartGene's Services for Faster, More Precise Identification of Bacteria and Fungi to be Used by The Johns Hopkins Hospital

...dentification of bacterial and fungal pathogens by sequence analysis. Some bacteria and fungi do not gr...s DNA, by integrating a number of tasks, including sequence editing, alignment, interpretation, creation of de...ers to manage and more fully utilize their genetic sequence data over time, completely independent of laborato...

Sangamo BioSciences Reports Second Quarter 2009 Financial Results

...g zinc finger DNA-binding protein (ZFP) technology for therapeutic gene regulation and modification. By engineering ZFPs that recognize a specific DNA sequence Sangamo has created ZFP transcription factors (ZFP TF(TM)) that can control gene expression and, consequently, cell function. Sangamo is also developi...

SEQUENOM Announces Launch of MassARRAY Compact 96 System

... including SNP genotyping and allelotyping, CNV analysis, quantitative gene expression analysis, quantitative methylation marker analysis, comparative sequence analysis of haploid organisms, SNP discovery, and oligonucleotide quality control. About SEQUENOM SEQUENOM is a life sciences company commi...

Sangamo BioSciences Announces Second Quarter 2009 Conference Call and Webcast

...g zinc finger DNA-binding protein (ZFP) technology for therapeutic gene regulation and modification. By engineering ZFPs that recognize a specific DNA sequence Sangamo has created ZFP transcription factors (ZFP TF(TM)) that can control gene expression and, consequently, cell function. Sangamo is also developi...

DNA Software, Inc. Awarded $2.5 M in NIH Funding to Develop Pioneering Nucleic Acid-based Technologies

... that have developed drug resistance. DNA Software has a breakthrough technology, called Nucleic Acid CADTM (NA-CADTM), which expands nucleic acid sequence information into all-atom 3D structure predictions of diverse RNA-based structures with near-crystal structure accuracy. With this NIH project, DNA S...

New and Updated Online Tutorials for dbGaP, GAD, and DGV from OpenHelix

... find, understand and link to more genomic variation details to navigate and customize your data using the genome browser how to perform a BLAT sequence search With the tutorials, researchers can quickly learn to effectively and efficiently use these resources. The scripts, handouts and other mat...

Researchers enlist DNA to bring carbon nanotubes' promise closer to reality

...roven to be insurmountable to date." The Nature article is titled "DNA sequence motifs for structure-specific recognition and separation of carbon nanotube...iscovery made by Tu and Zheng," says Jagota, "is that if you choose the DNA sequence correctly, it recognizes a particular type of CNT and enables us to sort th...

febit First to Offer Newly Published Mouse Genome on a Chip for DNA/RNA Detection and Enrichment

... febit Technology Enables the Conversion of New sequence Data into Biochips for Gene Expression Profiling and sequence Capture for Next-Generation Sequencing Within Days... efficient option for transforming digital genetic sequence information directly into a fully-applicable micro...

CEL-SCI Files Patent Application to Support Company's Treatment for More Virulent Strain of H1N1 Swine and Other Influenza Viruses

... novel T-cell modulation platform technology that enables CEL-SCI to design and synthesize proprietary immunogens. Any disease for which an antigenic sequence has been identified, such as infectious, parasitic, malignant or autoimmune diseases and allergies, are potential therapeutic or preventive sites for ...

Israeli scientists show bacteria can plan ahead

...ts that change in predictable ways. Their findings show that these microorganisms' genetic networks are hard-wired to 'foresee' what comes next in the sequence of events and begin responding to the new state of affairs before its onset. E. coli bacteria, for instance, which normally cruise harmlessly d...

Lethality of H1N1 Influenza Virus Increasing According to Latest Analysis of Virus Peptide Genomic Data

...lobal outbreak of H1N1 is increasing in its capacity for lethality. The new sequence data on PubMed of the past two weeks through June 10, 2009 showed an increa... lethality. Since the software also permitted the automated analysis of all sequence data available on PubMed for all previous years, it was noted that this is ...

DNA2.0 Awarded US Patents for Breakthrough Gene Optimization Technology -- Company's Unique Algorithm Enables Expression Yields up to 50 Times Greater than Competing Approaches

...erstood. DNA2.0 has cracked the code on optimizing sequence design and has been awarded two US patents coverin... expression by designing the most effective coding sequence is therefore essential. Despite the high value of sequence design, most currently used algorithms are based o...

Novavax and the NIH Agree to Evaluate a Virus-like Particle (VLP) Vaccine Candidate Against the Novel Influenza A (H1N1) Virus

...ovavax scientists produced the first batch of H1N1 VLPs within the company's laboratories in May, just three weeks after the CDC announced the genetic sequence of a novel influenza A (H1N1) virus. This strain of influenza was isolated from an infected person located in California. These VLPs contain the hema...

Sangamo BioSciences Announces Presentation at the Needham Life Sciences Conference

...the engineering of a class of DNA-binding proteins known as zinc finger DNA-binding proteins (ZFPs). By engineering ZFPs that recognize a specific DNA sequence Sangamo has created ZFP transcription factors (ZFP TF(TM)) that can control gene expression and, consequently, cell function. Sangamo is also develop...

MIT, BU engineer cellular circuits that count events

... the number of times a cell divides, or to study a sequence of developmental stages. They could also serve as ...rent RNA polymerase. The number of steps in the sequence is, in theory, limited only by the number of disti...DNA, flips it over and re-inserts it, altering the sequence in a predictable way. The DIC Counter consists...

Penguin Computing Forms OEM Agreement with Applied Biosystems for Scyld ClusterWare

...times. Scyld ClusterWare is seamlessly integrated with the SOLiD platform to execute primary and secondary analysis tasks such as image processing and sequence alignment. "After evaluating multiple cluster management products, we chose the Scyld ClusterWare for the processing of large amounts of ima...

CEL-SCI Developing Immune-Based Treatment Against Swine and Other H1N1 Flu Viruses Using Proprietary L.E.A.P.S. Technology

...a novel T-cell modulation platform technology that enables CEL-SCI to design and synthesize proprietary immunogens. Any disease for which an antigenic sequence has been identified, such as infectious, parasitic, malignant or autoimmune diseases and allergies, are potential therapeutic or preventive sites for ...

Swine Flu (H1N1) Infectivity to Increase Markedly and Lethality to Remain Low According to Latest Replikin* Peptide Genomic Data

...last week analyzed the most recent peptide genomic sequence data available and determined that the infectivity...company's quantitative analysis of the most recent sequence data available on PubMed, a standard scientific re...last week analyzed the most recent peptide genomic sequence data available and determined that the infectivity...