Sensitivity in Biological Technology

Breast-Specific Gamma Imaging (BSGI) Offers Greater Sensitivity Over Mammography, Ultrasound and MRI

American Journal of Roentgenology Study Reveals Conclusive Findings in the Detection of Invasive Lobular Carcinoma NEWPORT NEWS, Va., March 3 /PRNewswire/ -- Breast-Specific Gamma Imaging (BSGI) has been proven to be a highly sensitive imaging technique for the diagnosis of invasive lobular ...

SACHEM Launches 2-D HPLC e-Learning Program : New e-Learning Program Teaches Scientists How to Better Analyze and Prove Product Purity Through Greater Sensitivity and Precision in Identification of Trace Components

SACHEM announced today the launch of a new displacement chromatography e-Learning program. With the growing popularity of SACHEM’s Isolis™ displacers, SACHEM is offering scientists worldwide the ability to learn more about applying displacement chromatography in two dimensional High P...

New Dual Cold Probe From Varian, Inc. Increases Sensitivity and Reduces Analysis Times for 13C NMR Experiments

PALO ALTO, Calif., March 10 /PRNewswire-FirstCall/ -- Varian, Inc. (Nasdaq: VARI ) announced today its new XSens(TM) Dual Cold Probe. Designed for use with the Varian NMR System, the new probe is Varian's most sensitive probe for 13C detected NMR experiments. The XSens Probe offers producti...

Agendia Acquires Rights to the Discovery of a Major Drug Resistance Mechanism in Breast Cancer Potentially Leading to a Herceptin(R) Sensitivity Test

AMSTERDAM, October 15 /PRNewswire/ -- Agendia BV, world leader in the rapidly evolving field of molecular diagnostics, announced today that it has acquired the rights to the discovery of a major mechanism of resistance to the frequently-used breast cancer drug Herceptin(R), which is published ...

Clinical Pharmacology Study With AZILECT(R) (Rasagiline Tablets) Demonstrated It Does Not Increase Tyramine Sensitivity

Study Indicated Rasagiline Selectivity for Inhibiting MAO-B at Maximum Approved Dose KANSAS CITY, Mo., June 9 /PRNewswire/ -- Teva Neuroscience, Inc. today presented results from a clinical pharmacology study in which AZILECT(R) (rasagiline tablets) did not increase the risk of tyramine sensi...

Data Presented on Monogram HIV Tropism Tests at Retrovirus Conference sets New Standards of Assay Sensitivity

Company Continues to Lead Tropism Testing Field SOUTH SAN FRANCISCO, Calif., Feb. 7 /PRNewswire-FirstCall/ -- Monogram Biosciences, Inc (Nasdaq: MGRM ) today announced that data related to the company's advanced HIV tropism assay have been presented as multiple posters during the ...

Trace Analysis Optimizing Sensitivity Finnigan Surveyor PDA Detector

Chromatography and Mass Spectrometry Application Note L.Pereira, 1 M.Woodruff, 1 P.Deland, 2 D.Elmashni, 2 M.Euerby 3 1 Thermo Electron Corporation, Runcorn,UK 2 Thermo Electron Corporation, San Jose CA,USA 3 Astra Zeneca R&D, Charn...

Increased Analyte Sensitivity through the Utility of Enhanced Mass-Resolution on the FinniganTSQ Quantum Discovery

Chromatography and Mass Spectrometry Application Note Key Words Sensitivity Quantitation Finnigan TSQ Quantum Discovery Enhanced Mass- Resolution Xiaoying Xu 1 , Gary Paul 2 , Qiao Zhou1, Gregory Tucker 1 , and Walter Korfmacher 1 1 Department of D...

Wideband sensitivity of the FluoroLog-3

Introduction Many companies claim high sensitivity for their spectrofluorometers. In their specifications, instrument vendors often cite excitation of de-ionized water at 350 nm, which results in Raman emission at 397 nm (an energy loss of 3380 cm 1 ). This Rama...

Maintaining High Sensitivity when Working with Small-Volume Samples

Reduced-Volume Samples 20 L, 50 L, 250 L, or 1 mL

Biological Samples
enzymes polymers amino acids

Maximum Sensitivity
photon-counting superb imaging quality

Samples can be valuable. Either you dont want to waste them,...

Femtogram Sensitivity of the Antipsychotic Drugs Raclopride and Ritanserin Using a Varian 1200L LC/MS/MS

J. Beck and C. Schmidt Varian, Inc. Introduction Ritanserin (Tisterton) is a serotonin-2 antagonist drug shown to be effective in the treatment of anxiety and depression 1 while Raclopride acts as a dopamine D2 receptor antagonist. 2 These two compound...

High sensitivity quantitation of metabolites of nitrofuran antibiotics in animal tissue using LC/MS/MS

A sensitive and simple high performance liquid chromatograph tandem mass spectrometry (LC/MS/MS) method is presented for a simultaneous analysis of the metabolites of four nitrofuran antibiotics in chicken tissue. Abstract The animal meat samples were prepared by ho...

HIGH SENSITIVITY qRT-PCR

MessageSensor Reverse Transcription Kit For One Step qRT-PCR More sensitive than SuperScript II and other RNase H MMLV reverse transcriptases Linear quantitation of mRNA targets over a 106-fold range Quantita...

Increased Sensitivity in Microarray Analysis

Transcriptor Reverse Transcriptase in the Eberwine Target Preparation Workflow Reproducibility and sensitivity are key parameters for the quality of a gene expression profiling experimen...

Increase the Power and Sensitivity for Your cDNA Synthesis with the New Transcriptor Reverse Transcriptase

Transcriptor Reverse Transcriptase is a new recombinant reverse transcriptase (RT) expressed in E. coli. The enzyme has RNA-directed DNA polymerase activity, DNA-dependent DNA polymerase activity, unwinding activity, an...

Enhancing Ruggedness and Full-Scan MS Sensitivity Using Ion Sweep Technology

RohanA.Thakur, AndrewW. Guzzetta, and Julie A.Horner Ion Trap Analysis The data presented here can be acquired using a Thermo Finnigan LCQ Advantage, LCQ Deca XP, an...

cMaster RTplusPCR System for increased sensitivity and product length in RT-PCR

Abstract RT-PCR has become an essential method that allows researchers to determine the presence, structure and level of expression of an mRNA transcript in the organism, tissue or cell of interest. The basic protoc...

Improved Sensitivity for Staining RNA with SYBR Gold Stain

Eagle Eye II still video system provides quality images from nanogram quantities of RNA Genina Troutman Ian Miller Jeff Mueller Mike Kobrin Stratagene The SYBR Gold nucleic acid gel stain (Molecular Probes), combined with Stratagenes Eagle Eye II stil...

A Screen of shRNAs Targeting Tumor Suppressor Genes to Identify Factors Involved in Paclitaxel Sensitivity

Diana Ji, Stacy L. Deeds, and Edward J. Weinstein RNA interference methodologies have been utilized in small to large scale screening projects. The technology has allowed researchers to perform gene-silencing experiments in timeframes and target cells prev...

ALPCO Introduces a Mouse HMW and Total Adiponectin ELISA

...ource of bias in the ratio. The interest in animal models of insulin sensitivity in obese and pre-diabetic conditions continues to grow. Dr. Kelly Scribner ...lyst with ALPCO, states, "Adiponectin is positively associated with insulin sensitivity and this kit is specifically designed for mouse samples so it aids preclini...

Webcast Alert: Transgenomic Inc. Announces Second Quarter 2009 Earnings Release Conference Call Webcast

...0-1116. About Transgenomic: Transgenomic is a global biotechnology company that provides unique products and services for automated high sensitivity genetic variation and mutation analysis. Their offerings include systems, products, discovery and laboratory testing services to the academic and medi...

Debiopharm and MSM Protein Technologies Sign Agreement for Research and Development of Debio 0929, a Novel Oncology Biologic

...ounding scientist and subsequently licensed to MSM. Since then the Company has developed additional, novel technologies that provide greater power and sensitivity to the search for antibody drugs to multispanners. For more information on MSM, please visit: http://www.msmprotein.com About G-protei...

NeoGenomics Reports Second Quarter 2009 Results

...anoma from pre-malignant or dysplastic nevi with a sensitivity of approximately 87-90% and a specificity of appro...sible combination of genes to further maximize the sensitivity and specificity of this FISH test for the diagnosis of melanoma. Given the already high levels of sensitivity and specificity reported for this new test, we bel...

1 nano-step closer to weighing a single atom

...y of vibration when an eraser is attached, nanomechanical mass sensors work by measuring their change in vibration frequency as mass is added. The sensitivity of such nanomechanical devices is intimately connected to how much energy they displace. So researchers needed to understand how damping (loss of ener...

DNA Software, Inc. Awarded $2.5 M in NIH Funding to Develop Pioneering Nucleic Acid-based Technologies

...el DNA or RNA. None can accurately model the large variety of modified nucleotides that are added to or replace DNA and RNA sequences to increase the sensitivity and specificity of nucleic acid-based diagnostic tests and therapeutics. DNA Software is combining the unique features of kinetics and modified nucle...

American Mothers Seriously Concerned About Childhood Allergies, Siemens Survey Reveals

..., dust and a host of other allergens,( )may have higher rates of precision, sensitivity and in some instances safety, than other diagnostic options.(4,5) Blood tes... The reason third-generation allergen-specific IgE assays offer improved sensitivity and reliability is three-fold: They are quantitative -- able to m...

Hygeia Therapeutics Signs an Exclusive License with Yale University for Potent, Safe Topical Anti-Androgens

...i-androgens. The compounds are expected to be devoid of systemic activity and will be developed for skin and hair disorders associated with increased sensitivity to androgens. Holden, MA (PRWEB) July 20, 2009 -- Hygeia Therapeutics Inc. (the "Company" or "Hygeia") ...

Encorium Group Completes Sale of its U.S. Business to Pierrel Research USA; Announces Management Changes

...ies; (vii) the ability to maintain profit margins in a competitive marketplace; (viii) our ability to attract and retain qualified personnel; (ix) the sensitivity of our business to general economic conditions; (x) other economic, competitive, governmental and technological factors affecting our operations, mark...

Material world: Graphene's versatility promises new applications

...ory. This can be accomplished by adding counter ions to balance the charges resulting from impurities, thereby further lowering capacitance. The sensitivity of graphene's single atomic layer geometry and low capacitance promise a significant boost for biosensor applications. Such applications are a central...

Data on WaferGen's SmartChip(TM) System to be Presented at 3rd Annual Rediscovering Biomarkers Conference

...Chip Real-Time PCR System will be the first platform to combine the high-throughput capability and cost efficiencies of existing microarrays, with the sensitivity and accuracy of real-time PCR. This innovative system, combined with next-generation chemistry and optimized assays being developed by WaferGen, prom...

It's Not Just the Sun: deCODE Discovers Sequence Variants Affecting Susceptibility to Skin Cancer

... if inherited from the father than from the mother. "It is important to find genetic causes of BCC that do not appear to be modulated directly by sensitivity to the sun. This may bring us closer to understanding the underlying biology of a very common form of cancer, and KRT5 in particular may point us to n...

Encorium Group Updates Expected Timeframe with Respect to the Sale of its U.S. Business

...ies; (vii) the ability to maintain profit margins in a competitive marketplace; (viii) our ability to attract and retain qualified personnel; (ix) the sensitivity of our business to general economic conditions; (x) other economic, competitive, governmental and technological factors affecting our operations, mark...

Enigma Diagnostics Announces Successful Evaluation of the Enigma FL by the UK's Veterinary Laboratories Agency

...agnostic instrument platforms for decentralised and point-of-care settings. Enigma's innovative and proprietary technology combines the speed and sensitivity of real-time PCR (polymerase chain reaction) with the simplicity needed for field-based, decentralised and point-of-care tests providing results from ...

Insmed Announces Results of IPLEX(TM) Phase II Trial in Myotonic Muscular Dystrophy

...(TM) did, however, demonstrate improvements in standard measures of insulin sensitivity and reductions in fasting glucose, fasting insulin, cholesterol and triglyc...al endpoints. However, the statistically significant improvement in insulin sensitivity seen in this study suggests that an additional phase II study in MMD patien...

Exosome Diagnostics and DxS Diagnostic Innovations Collaborate to Develop Blood-Based Tests for Key Cancer Mutations

...corpion probes target directly from blood." "Combining the ability to pull high-quality mutations from a simple blood draw with the unparalleled sensitivity and specificity of our Scorpion assays will provide our pharmaceutical and research customers with an ideal solution in personalized medicine," said D...

BRAHMS, Cezanne and Lumiphore Announce Partnership for Diagnostic Tests

...gnostic markets, from central labs to point-of-care applications. Detection sensitivity and simplicity of use as well as material cost reductions in reagent use, l...Lumi4(R)-Tb to replace the current Europium Cryptate will not only increase sensitivity of BRAHMS diagnostic tests, but will also allow the development of multiple...

Knocking the Wind Out of Asthmatics: Help from Hippocrates

... About Cell Science Systems Cell Science Systems (CSS) is a vertically integrated life sciences company and the worldwide market leader in food sensitivity testing as the manufacturer of the ALCAT Test. ALCAT identifies cellular reactions to over 300 foods and chemicals. These inflammatory reactions are l...

Light sensor breakthrough could enhance digital cameras

...rrent that flows as a result. Normally, each photon is converted into at most one exciton. This lowers the efficiency of solar cells and it limits the sensitivity of digital cameras. When a scene is dimly lit, small portable cameras like those in laptops suffer from noise and grainy images as a result of the sma...

Three Rivers Announces Positive Results from Phase 3 DIRECT Trial of Once-Daily INFERGEN(R) with Ribavirin in Hepatitis C Virus Treatment Failures

... Patients with cirrhosis were less likely to benefit from retreatment with INFERGEN and RBV unless they displayed previous interferon sensitivity of at least 1-log drop in viral levels on prior therapy. About Consensus Interferon (INFERGEN(R)) Consensus Interferon or INFERGEN (R) is ...

invivodata Announces ePROficiency 2009 Web Seminar Series

...s delivering insight on specific aspects of PRO in clinical research and answering questions on topics including: Improving Measure sensitivity in Early Stage Research - June 18 A Conceptual Model in the Context of a Global Drug Development Program - July 30 Developing PROs: C...