Sensitive in Biological Technology

Winning University of Melbourne Ph.D. research boosts the search for sensitive sensors

Research that could lead to brighter LCD screens, more efficient solar panels, improved biomedical imaging and high-tech security sensors has won the University of Melbourne's Chancellor's Prize for Excellence in PhD. Dr Daniel Gomez, who completed his thesis in the School of Chemistry, has she...

The sensitive side of carbon nanotubes: Creating powerful pressure sensors

Troy, N.Y. Blocks of carbon nanotubes can be used to create effective and powerful pressure sensors, according to a new study by researchers at Rensselaer Polytechnic Institute. Taking advantage of the materials unique electrical and mechanical properties, researchers repeatedly squeezed a 3-m...

Nanotechnology makes supertelescopes much more sensitive

Nanotechnologist Chris Lodewijk has succeeded in significantly increasing the sensitivity of the new supertelescopes in Chile. He will receive his PhD on this topic at Delft University of Technology on Monday 2 February. In Chile's Atacama desert, technicians and astronomers from around the wor...

A highly sensitive ATP-luminescence assay using VICTOR2 with the dispenser option

INTRODUCTION In high sensitivity flash type luminescence assays the measurement is done just after dispensing the activating reagent or after a short delay time. Over the past years luminescence substrates have been improved towards providing more stable signal. These so-call...

The combination of monolithic columns and modern HPLC/MS/MS instrumentation for high chromatographic throughput and sensitive detection of beta-agonists

Beta-agonists are group A substances of the European guideline 93/257/EWG (revision 98/536/EG) having an anabolic effect and not licensed. Thus, they have to be determined in veterinarian samples like muscle, liver, retina, and urine. The coupling of High Pressure Liquid Chromatography (H...

Development of a sensitive enzyme fragment complementation assay for cyclic adenosine 3', 5' monophosphate and its validation for pharmacological screening at G protein-coupled receptors

Key words: cAMP • GPCR • enzyme fragment complementation • LEADseeker • assay miniaturization G protein-coupled receptors (GPCRs) are the largest family of transmembrane receptors and are responsible for the transduction of ...

Highly Sensitive microRNA Array Performance

mir Vana miRNA Probe Set and mir Vana miRNA Labeling Kit Detecting miRNAs on Microarrays MicroRNAs (miRNAs) are extremely small RNA species that represent approximately 0.01% of the total mass ...

Novel MicroRNA Array Technology for Sensitive miRNA Profiling

Uncover Critical Regulatory Pathways by Analyzing a Complete Set of Human and Mouse miRNAs The miRNA gene family contains hundreds of translation regulators, yet their presence and function has only re...

The DIG System Nonradioactive and Highly Sensitive Detection of Nucleic Acids

Roche Applied Science was one of the first companies to offer a nonradioactive technology allowing customers to move away from the use of hazardous radioactive isotopes. Even after 15 years and the increasing availabili...

Gene Expression Arrays: Highly Sensitive Detection of Expression Patterns with Improved Tools for Target Amplification

Introduction As the human genome project is completed, microarray technology offers the potential to study the genomes complexity. This technology facilitates the direct ext...

Simple, Sensitive Isotyping of Mouse Monoclonal Antibodies

Monoclonal antibody isotyping in only 5 minutes Weiping Yang Matt C. Petre Darrel Holmes Peter L. Pingerelli Stratagene Cloning Systems, Inc. Stratagenes IsoDetect mouse monoclonal antibody isotyping kit is a simple, rapid and sensitive method for identifying mouse monoclona...

Five Questions About Protopic (tacrolimus) Ointment

...th breaks in between.(4) After first-line treatments, or when those treatments are not advisable, Protopic has been shown to be safe and effective in sensitive and/or difficult to treat areas when used as directed. Is Protopic suitable for children? Protopic is available in two conc...

1 nano-step closer to weighing a single atom

... at the single molecule level. Researchers are interested in nanosized materials because the smaller the components of a detection device, the more sensitive it is. In this study, the team from the University of Melbourne, Argonne's Center for Nanoscale Materials in Illinois and the University of Chicag...

SEQUENOM Announces Launch of MassARRAY Compact 96 System

...MassARRAY Compact 96 system delivers: exceptional performance which makes it ideal for the most demanding applications; and highly sensitive and specific mass spec-based detection of low frequency mutations that are typically undetected using conventional techniques. The...

Global One Consulting Announces Exclusive Contract to Expand Saigene Biotech, Inc. Sales in Emerging Markets

... It is currently being used by major research and commercial entities worldwide. The Saigene assay enables automated, walk-away testing that is highly sensitive and able to quickly detect the presence of algal cells, even when they are not detectable under a microscope. Algae, the most abundant photosynthetic...

NYU physicists find way to explore microscopic systems through holographic video

...y promises a previously unattainable level of miniaturization for medical diagnostic tests and creates possibilities for running very large numbers of sensitive medical tests in parallel. ...

DermTech and Stiefel Laboratories, Inc. to Further Evaluate EGIR(TM) Technology

...netic material to differentiate potentially life-threatening melanoma from other forms of pigmented lesions. Studies to date show the test to be 100% sensitive and 88% specific. Research is also underway to use the EGIR technology to develop highly accurate, non-invasive tests for other cancers and diseases...

Monitoring Circulating Tumor Cells With the CellSearch(R) System Can Predict Prognosis in Metastatic Breast Cancer

...ng to a newly published report in the July 10 issue of the Journal of Clinical Oncology . The retrospective study compared how well CTCs and a more sensitive than conventional modality, fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT), predicted survival in MBC patients on st...

Nanopillars promise cheap, efficient, flexible solar cells

...more surface for collecting light. Computer simulations have indicated that, compared to flat surfaces, nanopillar semiconductor arrays should be more sensitive to light, have a greatly enhanced ability to separate electrons from holes, and be a more efficient collector of these charge carriers. "Unfortuna...

Study on keeping nuclear bombs from US ports shows misplaced fear over cargo scanning cost

...ousands of containers, stacked up to six-high. Targeted containers must then be moved to an inspection facility where their contents are scanned using sensitive equipment. This is a slow process that involves sophisticated tools and specialized training that only support limited throughput. Consequently, there...

DOR BioPharma Announces Issuance of European Patent for its LPM(TM) Oral Drug Delivery Technology

...erse micelles) that promote the intestinal absorption of peptides and other sensitive drugs that cannot otherwise be given orally. "The issuance of the Eur...ctivation of peptides by enzymes in the upper gastrointestinal tract. Other sensitive drugs that can be delivered orally with the LPM(TM) system include various ...

Researchers unite to distribute quantum keys

... achievable by classical methods. The photons themselves are used to distribute cryptographic key to access encrypted information, such as a highly sensitive transaction file that, say, a bank wishes to keep completely confidential, which can be sent along practical communication lines, made of fibre optics...

Lixte Biotechnology Holdings' Lead Compound, LB-1.2, Enhances the Effectiveness of Standard Cancer Chemotherapy in Animal Models

...improving the effectiveness of several standard anticancer drugs not only against tumors of the brain and neural tissue but also against other cancers sensitive to drugs that work by damaging DNA. Safety, of course, must be demonstrated first in animal studies and subsequently in Phase I clinical trials before...

Unexpectedly long-range effects in advanced magnetic devices

...odern high-density disk drives usually exploit a version of the giant magnetoresistance (GMR) effect, which uses such layered structures for extremely sensitive magnetic field detectors. Arrays of nanoscale sandwiches of a similar type might be used in future data storage devices that would outdo even today's ...

Zvetco Biometrics Delivers a Cohesive Security System Integrating Fingerprint Biometrics with Sun Identity Management Solutions.

...available on Sun's Identity Management Suite to provide strong authentication solutions for government and commercial applications. Whether protecting sensitive enterprise applications, meeting the demands of regulatory compliance, or complying with federal mandates, the Zvetco Verifi™ and BiObex™ ...

Rules-Based Medicine, Inc. Launches DiscoveryMAP(TM) Service for Drug and Diagnostic Development

... Drug developers have increasingly turned to the use of biomarkers in order to increase efficiency and reduce cost and risk. Researchers require sensitive and quantitative data to pinpoint the biomarker patterns that are either directly involved in the disease process or are useful surrogate markers. Wh...

Bilayer graphene gets a bandgap

...ectrical resistance, or transport, they decided to measure its optical transmission. "The problem with transport measurements is that they are too sensitive to defects," says Wang. "A tiny amount of impurity or defect doping can create a big change in the resistance of the graphene and mask the intrinsic b...

MEDomics Announces MitoDx(TM), the First NextGen Mitochondrial Genome Diagnostic Test

... Highly sensitive Genetic Test Provides Early Diagnosis of Mitochondrial Diseases LOS ANGELES, June 9 /PRNewswire/ -- MEDomics, LLC ( www.medomics.com ) announce...

Researchers solve 'bloodcurdling' mystery

... protein von Willebrand factor (VWF). By manipulating single molecules of this A2 domain, the researchers found that the A2 domain acts as a highly sensitive force sensor, responding to very weak tensile forces by unfolding, and losing much of its complex three-dimensional organization. This unfolding event...

ChemImage Works to Improve Existing Methods of Imaging Untreated Fingerprints on Paper Substrates

...cessing techniques for fingerprints, it can also provide a means of examining untreated prints, especially if the evidence may contain DNA or includes sensitive documents or art," said Belechak. About ChemImage ChemImage Corporation, headquartered in Pittsburgh, is a world leader in Chemical Imaging tec...

Pixantrone Significantly Increases Complete Remissions, Overall Response Rates, Frequency of Durable Remissions and Progression Free Survival in Patients with Relapsed and Refractory Aggressive Non-Hodgkin's Lymphoma

...se III single-agent trial of pixantrone for patients with relapsed or refractory, aggressive NHL who received two or more prior therapies and who were sensitive to treatment with anthracyclines. The trial enrolled 140 patients and patients were randomized to receive either pixantrone or another single-agent dr...

Poxel SAS Set up to Find Innovative Solutions for Metabolic Diseases Management

...ipeline. Neither Merck KGaA nor Merck Serono is shareholders of Poxel. About Type 2 Diabetes: Type 2 Diabetes is defined by a failure of sensitive tissues to respond to insulin, a hormone involved in glucose and fatty acid metabolism, Type 2 diabetes hence being known as non-insulin-dependent dia...

Doctors in New Hampshire Now Treating Cancer with Non-Invasive Image-Guided Radiosurgery Using Novalis Tx(TM) Technology

...s already weakened by the patient's chronic pulmonary disease. The Novalis Tx is an exceptional machine for treating tumors and malignancies in highly sensitive areas of the body." The American Cancer Society estimated that in 2008, doctors diagnosed 215,020 new cases of lung cancer in the US, with over 1...

ImmunoVaccine Technologies Collaborates with NRC Institute for Biodiagnostics Atlantic to measure effectiveness of DepoVax(TM) with novel MRI Imaging

...tumour growth. "This research has the potential to deliver extremely sensitive MRI analysis, down to the individual cell level, and we will see, for the f...established in biomedical research. This research aims at developing highly sensitive and quantitative techniques for monitoring tumor progression and vaccine cl...

ImmunoVaccine Technologies Collaborates with NRC Institute for Biodiagnostics Atlantic to measure effectiveness of DepoVax(TM) with novel MRI Imagin

...cing tumour growth. "This research has the potential to deliver extremely sensitive MRI analysis, down to the individual cell level, and we will see, for the f...established in biomedical research. This research aims at developing highly sensitive and quantitative techniques for monitoring tumor progression and vaccine cl...

Low Occurrence of Severe Cardiac Side Effects Despite Extensive Prior Doxorubicin Treatment Reported in Pixantrone Pivotal Trial

...rial was a phase III single-agent trial of pixantrone for patients with relapsed, aggressive NHL who received two or more prior therapies and who were sensitive to treatment with anthracyclines. The trial enrolled 140 patients and patients were randomized to receive either pixantrone or another single-agent dr...

Spectros T-Stat Tissue Oximeter Clinical Studies Presented at PAS (Pediatric Academic Societies') Conference

... devices that shed light on ischemia and cancer. The company's lead product, the T-Stat Tissue Oximeter, was the first medical device FDA-approved as sensitive to ischemia, an insufficient blood flow to tissue. T-Stat is the only commercially-available tissue oximeter that utilizes state-of-the-art visible l...

A New Era in the Application of Lab-on-a-Chip to Rapid Point-of-Care Diagnosis

... and other acute respiratory infections. The MOBILE FIELD UNIT will deliver sensitive and accurate diagnostic capabilities to resource-limited urban, rural and r...the conventional gel-based RT-PCR technique. All three platforms are highly sensitive and specific, giving rapid and accurate results within two to four hours. ...

Brain research shows past experience is invaluable for complex decision making

...similarity between visual patterns," explains Dr. Kourtzi. "Our use of brain imaging in combination with mathematical techniques enabled us to extract sensitive information about brain signals that reflected the participant's choice." "What we've shown is that we don't just get better at the task of picking...

Transgenomic and Power3 Medical Introduce NuroPro(R) Tests for Alzheimer's and Parkinson's Diseases at AAN Annual Meeting

...wer3 operates a state-of-the-art CLIA certified laboratory in The Woodlands (Houston), and continues to evolve and enhance its IP portfolio, employing sensitive and specific combinations of biomarkers it has discovered from a broad range of diseases as the basis of highly selective blood-based tests for ALS, A...