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SNP in Biological Technology

QMed, Inc. Reports July Medicare SNP Enrollments

EATONTOWN, N.J., Aug. 16 /PRNewswire-FirstCall/ -- QMed, Inc., (Nasdaq: QMED) today reported new enrollment figures for its Medicare Special Needs Plans in New Jersey and South Dakota, including its SNP for dual eligible members. QMedCare of New Jersey added 55 new members to its SNP for the c...

Third Wave Achieves Milestone, Delivers 200,000 SNP Assays to RIKEN In Japan

MADISON, Wis. -- Third Wave Technologies Inc. (Nasdaq: TWTI) today announced it delivered a total of 200,000 single nucleotide polymorphism (SNP) assays to RIKEN in Japan for use in various large scale genotyping projects. Since the beginning of 2003, Third Wave has been supplying its Invader ...

Oragene is compatible with TaqMan SNP genotyping

J. Chartier and H.C. Birnboim DNA Genotek Inc., Ottawa, ON, Canada DNA collected with Oragene works well with TaqMan SNP Genotyping Assays. SNPs in the thymidylate synthetase and apolipoprotein E genes were reliably detected. ...

Real-Time PCR/Melt-Curve Analysis: SNP Detection With FRET, Rev A

Larissa Tan, Marni Brisson, Robert Park, and Keith Hamby, Bio-Rad Laboratories, 2000 Alfred Nobel Drive, Hercules, CA 94547 USA Introduction The detection of fluorescence resonance energy transfer (FRET) through real-tim...

Rapid SNP Genotyping of the Pharmacogenomically Important Allele CYP2D6*4 Using Real-Time qPCR on the DNA Engine Opticon 2 System

Surekha Karudapuram, Ph.D. and David Batey Ph.D. MJ Research, Inc., South San Francisco, CA Abstract A two-color real-time quantitative PCR (qPCR) protocol was used on the MJ Research DNA Engine Opticon 2 system to genotype the CYP2D...

SEQUENOM Announces Launch of MassARRAY Compact 96 System

...system facilitates a number of nucleic acid analysis applications including snp genotyping and allelotyping, CNV analysis, quantitative gene expression ana...lation marker analysis, comparative sequence analysis of haploid organisms, snp discovery, and oligonucleotide quality control. About SEQUENOM S...

DNA Software, Inc. Awarded $2.5 M in NIH Funding to Develop Pioneering Nucleic Acid-based Technologies

...s a platform program for the design, simulation, and analysis of probes/primers, RT-PCR, qPCR, Multiplex PCR, Taqman, Beacons, Scorpions, Microarrays, snp detection, FRET assays, RNAi, LATE-PCR, plus new formats. OMP Developer EditionTM (OMP DE™) brings customizable, command line, high-throughput ...

It's Not Just the Sun: deCODE Discovers Sequence Variants Affecting Susceptibility to Skin Cancer

... The study also provided conclusive evidence that a previously identified snp in the TERT-CLPTM1L region of chromosome 5 confers susceptibility to BCC but protects agains cutaneous melanoma. A previously known snp in the SLC45A2 gene on chromosome 5 was confirmed to confer risk of squamou...

deCODE Discovers a Gene Linked to Risk of Kidney Stones and Osteoporosis

... upcoming print edition of the journal. The snp is in the gene encoding claudin 14 (CLDN14), a pro...etabolism of calcium. The results suggest that the snp may be contributing to increased calcium excretion... task is to build on our understanding of how this snp increases risk of these diseases and how this path...

Best of Show Awards Winners Named at Bio-IT World Conference & Expo

... Workbench: Reference assembly of Sanger and Next Generation Sequencing data De novo assembly of Sanger and Next Generation Sequencing data snp detection on whole genomes of any size CT Renaissance™, a deliverable centric, enterprise-class completely integrated and automated software ...

DNA Software, Inc. Honored as One of the 2009 "Michigan 50 Companies to Watch"

...s a platform program for the design, simulation, and analysis of probes/primers, RT-PCR, qPCR, Multiplex PCR, Taqman, Beacons, Scorpions, Microarrays, snp detection, FRET assays, RNAi, LATE-PCR, plus new formats. OMP Developer EditionTM (OMP DE™) brings customizable, command line, high-throughput ...

Real Time Genomics to Show SLIM Search(TM) Technology on Windows HPC Server 2008 at Bio-IT World Conference

... functions that are highly tolerant of mismatches such as indels and substitutions. This makes SLIM Search well suited to challenging problems such as snp discovery during disease investigation, where millions of reads must be accurately mapped against the full human genome. Working with Microsoft, ...

Beyond associations: Colorectal cancer culprit found

...," that are more prevalent in patients with a specific disease. However, a snp associated with a disease is not necessarily the culprit but it raises a r... to test the biological consequences of this SNP. The group found that the snp causes the expression of a nearby gene, called SMAD7 , to decrease. SMAD7...

Frost & Sullivan Lauds BioTrove for Providing Research-Enabling Life Sciences and Drug Discovery Technologies

...Platform enables genomics researchers to generate snp and real time qPCR data in the hundreds of thousan... Life Technologies globally markets the OpenArray snp genotyping platform under the TaqMan(R) OpenArray(R) snp Genotyping brand. BioTrove is a licensee of Life ...

Discovery of a new retinal gene involved in childhood blindness

...ents that are negative for this detailed screen are then subjected to a second DNA chip, this one to identify significant stretches of homozygosity in snp markers. SNPs are single nucleotide repeats, which are natural variations in the human genome. These homozygous regions may contain new genes and are ...

Speid & Associates Partners With Genizon BioSciences to Reduce Attrition Rates of New Drug Compounds

...nslated into clinical practice through collaborative research with academic and clinical leaders. Genizon also provides high throughput, high quality snp genotyping, genetic analysis, gene expression and pharmacogenomics services to academic institutions, research organizations and the biopharmaceutical...

Pigs to Be Genotyped to Improve Selection and Breeding for Pancreatic Islet Cell Research

...ompany serving the agribusiness, food safety, biomedical and pharmaceutical markets. GeneSeek's high throughput genotyping capabilities range from one snp to a million SNPs per sample and are relevant to gene discovery, diagnostic testing, marker-assisted breeding and identity management across many spec...

Multinational deCODE Study Identifies New Link Between Inflammation and Heart Attack

...ntries above as well as from Germany, Sweden, Australia, and South Korea. A snp on chromosome 2q12 was associated with increased risk of asthma, and three ...d Kari Stefansson, CEO of deCODE and senior author on the study. The snp on chromosome 12q24 associated with heart attack risk is in the SH2B3 gene ...

deCODE Discovers First Genetic Variant Conferring Increased Risk of Essential Tremor

...ase is and directly point the way to the development of new therapies. This snp is in a gene involved in many of the processes that one would expect to be ... 20% of the general population carry one copy of the at-risk version of the snp and 5% carry two copies, corresponding to a roughly 55% and 140% higher lik...

deCODE to Integrate New Genetic Risk Factor for Type 2 Diabetes Into Its deCODEme(TM) Personal Genome Scan Service

...m Europe and the United States. The analysis identified a version of single snp within the gene encoding melatonin receptor IB (MTNR1B) that was associated...levels. The deCODE team then demonstrated in its Icelandic cohort that this snp also associated with an increased risk of T2D, a finding that was then repl...

deCODE genetics Announces Third Quarter 2008 Financial Results

...f European descent carry two copies of the first variant, a version of a snp on chromosome 8q24, putting them at a 50% higher risk of developing blad...variant. Individuals who carry two copies of a common version of another snp on chromosome 3 were found to be at a 40% higher risk of the disease tha...

Diagenic Partners With DNAVision to Offer First Breast Cancer and Alzheimers Gene-Expression Blood Tests

... of applied pharmacogenetic & pharmacogenomic services. DNAVision offers the powerful combination of different technologies in expression profiling, snp genotyping and sequencing in a high quality environment (First European laboratory to be ISO17025 accredited). DNAVision is a spin-off of University o...

BioNanomatrix Announces Appointment of Dr. Pui-Yan Kwok to Its Scientific Advisory Board

... - Pioneer in High Throughput snp Discovery Brings Expertise in Human Genome Haplotyping - PHILADELPHIA, Oc...p Consortium Steering Committee. The inventor of several fluorescence-based snp genotyping methods, Dr. Kwok more recently has been developing mapping and ...

LI-COR Biosciences Offers $1.75 Million in Matching Funds for Undergraduate Genomics Education

...OR genomic analysis systems are used in academic labs worldwide for a variety of research applications including sequencing, microsatellites, AFLP(R), snp discovery and reverse genetics research. Complete information on how schools may apply for a grant is available at http://www.licor.com/gemf . Dead...

deCODE genetics Announces Second Quarter 2008 Financial Results

...the ASIP (agouti signaling protein) gene on chromosome 20 that greatly increase the likelihood of an individual being prone to freckles and sunburn. A snp in the TYR (tyrosinase) gene on chromosome 11, previously linked by deCODE to eye color, was here shown also to confer susceptibility to sunburn. The ...

Norgen Biotek Corp. Launches Four New Kits for the Purification of RNA and DNA from Plants and Fungi

...he procedure yields sufficient fungal DNA to be used in a number of downstream applications including Real-Time PCR, sequencing, Southern blotting and snp analysis and the total procedure can be completed less than 60 minutes. "Our new line of kits to isolate RNA and DNA from plants represents an excit...

deCODE genetics Announces First Quarter 2008 Financial Results

...cer. In April, deCODE scientists reported a clear link between a single snp and susceptibility to nicotine dependence. Moreover, in part because of... this impact on smoking behavior, each copy of the risk variant of this snp confers an approximately 30% increase in risk of lung cancer and a 20% ...

Olympus FluoroPoint(TM) System Provides High-Sensitivity Single Molecule and Protein Interaction Analysis for Screening and Research

...oint provides scientists with highly accurate and reliable data for studies involving protein-protein interactions, DNA, RNA, receptor binding, siRNA, snp genotyping, enzyme reactions, polymerization, thermodynamics, and other processes and mechanisms. Useful in a wide variety of facilities, it provides ...

A Smoking Gene: deCODE Shows How a Single Variant in the Sequence of the Genome Confers Nicotine Dependence and Risk of Lung Cancer and Other Disease

...health challenges. Not only have we made a convincing link between a single snp and a behavioral disorder -- greater smoking quantity and addiction to nico...than 10,000 smokers participating in deCODE's research, and the "T" version snp rs1051730 was shown to be more common in heavier smokers than in smokers ov...

Center for Molecular Medicine Selected to Provide DNA Analysis for Children's Oncology Group Leukemia Study

...lly occurring variations in human DNA, known as Single Nucleotide Polymorphisms (SNPs), serve as signposts or markers in the genome. Associating these snp markers with diseases in different individuals provides opportunity for highly specific diagnostic tests, and, even more exciting, provides insights i...

GeneSeek Selects the British Midlands as Base for New UK/European Operations

...tic protein production and discovery. GeneSeek enables development, testing and pilot production under one roof for products ranging from diagnostic snp panels to biologics for use in agriculture, pharmacogenomics, clinical diagnostics and health care. GeneSeek has developed unique expertise and capabi...

Susan G. Komen for the Cure Announces Recipients of 2007 Komen Brinker Award for Scientific Distinction

...(BES) and, more recently, nanotechnology. Dr. Gray was an early adopter of technologies such as transcriptional profiling, high throughput analysis, snp array CGH and molecular inversion probes. By integrating data received from these technologies, Dr. Gray has made significant advancements in developi...

RainDance Technologies Appoints McNary President and CEO

...t a variety of industrial and research applications, including DNA sequencing preparation, enzyme engineering, functional cell sorting, multiplex PCR, snp detection, gene expression, and RNAi functional assays. "Our Professional Laboratory System is game-changing technology that has attracted a tremend...

Consortium publishes Phase II map of human genetic variation

...led by the HapMap consortiums decision to make its snp datasets immediately available in public databases...more exciting findings in the future. The improved snp coverage offered by the Phase II HapMap, along wit...tested virtually the entire known catalog of human snp variation on the HapMap samples, as well as contri...

SeqWright Unveils ABI SOLiD(TM) Next Generation Genetic Analysis System

...Wright's ability to offer cutting-edge services in areas including whole genome sequencing, re-sequencing, Transciptome analysis, small RNA discovery, snp detection, Epigenomic and Metagenomic studies. In addition, the SOLiD(TM) platform significantly increases the sequencing capacity at SeqWright and p...

REPLI-g Mitochondrial DNA Kit

... Applications REPLI-g amplified mitochondrial DNA can be used in a variety of downstream applications, including: snp and STR genotyping RFLP and Southern blot analysis Sequence analysis ...

REPLI-g UltraFast Mini Kit

... Applications REPLI-g amplified genomic can be used in a variety of downstream applications, including: snp and STR genotyping RFLP and Southern blot analysis Comparative genome hybridization (CGH) PCR and real-time PCR ...

FlexiPlate siRNA

... potential to cause off-target effects are selected. snp avoidance siRNA design is optimized to avoid all known single n...P database. This increases siRNA potency, as an siRNA spanning a snp will vary in its effectiveness. Interferon motif avoidance ...

SNPs Powerful Tools for Association Studies

...rited from their mother and one from their father, snp analysis will result in one of the possible diplotypes. (Figure 2.) At this snp locus there are two alleles: T or C. Persons A and...ow frequencies. In the Applera genomic initiative, snp assays in the initial release of the off-the-shelf...

Oragene and Whole Genome Amplification with GenomiPhi

... test the quality of the amplified DNA for PCR and snp genotyping. Materials and M...thymidylate synthetase gene. snp genotyping A TaqMan snp Genotyping Assay for the thymidylate synthetase (T...
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